Mlembi: Clyde Lopez
Tsiku La Chilengedwe: 20 Kulayi 2021
Sinthani Tsiku: 18 Novembala 2024
Anonim
Pharmacology 881 c AIDS HIV Treatment Therapy Tenofovir Lamiuvdine Emtricitabine EfaVirenz
Kanema: Pharmacology 881 c AIDS HIV Treatment Therapy Tenofovir Lamiuvdine Emtricitabine EfaVirenz

Zamkati

Efavirenz, lamivudine ndi tenofovir siziyenera kugwiritsidwa ntchito pochiza matenda a chiwindi a hepatitis B (HBV; matenda opitilira chiwindi). Uzani dokotala wanu ngati muli ndi HBV kapena mukuganiza kuti mwina muli ndi HBV. Dokotala wanu angakuyeseni kuti muone ngati muli ndi HBV musanayambe kumwa mankhwala ndi efavirenz, lamivudine ndi tenofovir. Ngati muli ndi HBV ndipo mumamwa efavirenz, lamivudine ndi tenofovir, matenda anu akhoza kukulirakwirani mwadzidzidzi mukasiya kumwa efavirenz, lamivudine ndi tenofovir. Dokotala wanu amakupimirani ndikukuyesani mayeso a labu pafupipafupi kwa miyezi ingapo mutasiya kumwa efavirenz, lamivudine ndi tenofovir kuti muwone ngati HBV yanu yaipiraipira.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira efavirenz, lamivudine, ndi tenofovir.

Kuphatikiza kwa efavirenz, lamivudine, ndi tenofovir amagwiritsidwa ntchito pochiza HIV mwa akulu ndi ana. Efavirenz ali mgulu la mankhwala otchedwa non-nucleoside reverse transcriptase inhibitors (NNRTIs). Lamivudine ndi tenofovir ali mgulu la mankhwala otchedwa nucleoside ndi nucleotide reverse transcriptase inhibitors (NRTIs). Amagwira ntchito pochepetsa kuchuluka kwa kachilombo ka HIV mthupi. Ngakhale efavirenz, lamivudine ndi tenofovir sizingachiritse HIV, mankhwalawa amachepetsa mwayi wanu wopeza matenda a immunodeficiency syndrome (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa pamodzi ndi kugonana mosatekeseka ndikusintha zina pamoyo wanu kumachepetsa chiopsezo chotenga kapena kufalitsa kachilombo ka HIV kwa anthu ena.


Kuphatikiza kwa efavirenz, lamivudine, ndi tenofovir kumabwera ngati piritsi loti mutenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku opanda kanthu m'mimba (osachepera ola limodzi musanadye kapena maola awiri mutadya). Tengani efavirenz, lamivudine, ndi tenofovir mozungulira nthawi yomweyo tsiku lililonse. Kutenga efavirenz, lamivudine, ndi tenofovir nthawi yogona kungapangitse zovuta zina kukhala zosavutitsa. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani efavirenz, lamivudine, ndi tenofovir ndendende monga mwalamulira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Pitirizani kumwa efavirenz, lamivudine, ndi tenofovir ngakhale mutakhala bwino. Osasiya kumwa efavirenz, lamivudine, ndi tenofovir osalankhula ndi dokotala. Mukasiya kumwa efavirenz, lamivudine, ndi tenofovir ngakhale kwakanthawi kochepa, kapena kudumpha mlingo, kachilomboka kakhoza kulimbana ndi mankhwala ndipo kumakhala kovuta kuchiza.

Kuphatikiza kwa efavirenz, lamivudine, ndi tenofovir kumapezeka ndi mayina amtundu wa Symfi ndi Symfi Lo. Mitundu iwiriyi imakhala ndi mankhwala ofanana, ndipo sangasinthane. Onetsetsani kuti mukulandira efavirenz, lamivudine, ndi tenofovir kokha omwe adakupatsani dokotala. Funsani wamankhwala wanu ngati muli ndi mafunso okhudza mtundu wa efavirenz, lamivudine, ndi tenofovir yomwe mudapatsidwa.


Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge efavirenz, lamivudine, ndi tenofovir,

  • uzani dokotala wanu komanso wamankhwala kuti ngati muli ndi vuto la efavirenz, lamivudine, tenofovir, mankhwala ena aliwonse, kapena chilichonse chopezeka mu efavirenz, lamivudine, ndi piritsi la tenofovir. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • Muyenera kudziwa kuti efavirenz, lamivudine ndi tenofovir amapezekanso payekhapayekha ndi mayina a Sustiva, Epivir, Epivir-HBV (omwe amagwiritsidwa ntchito pochizira matenda a hepatitis B), Vemlidy (omwe amagwiritsidwa ntchito pochizira hepatitis B), ndi Viread, komanso kuphatikiza ndi mankhwala ena omwe ali ndi mayina a Atripla, Biktarvy, Combivir, Complera, Descovy, Epzicom, Genvoya, Odefsey, Stribild, Symfi, Triumeq, Trizivir, ndi Truvada. Uzani dokotala wanu ngati mukumwa mankhwala aliwonsewa kuti mutsimikizire kuti simulandiranso mankhwala omwewo kawiri.
  • Uzani dokotala wanu ngati mukumwa elbasvir / grazoprevir (Zepatier). Dokotala wanu angakuuzeni kuti musamwe efavirenz, lamivudine, ndi tenofovir ngati mukumwa mankhwalawa.
  • Uzani dokotala ndi wazamankhwala mankhwala ena omwe mumalandira kapena mavitamini omwe mumalandira kapena mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: acyclovir (Sitavig, Zovirax); adefovir (Hepsera); aminoglycosides monga gentamicin; artemether / lumefantine (Coartem); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) ndi naproxen (Aleve, Naprosyn); atorvastatin (Lipitor, mu Caduet); atovaquone / proguanil (Malarone); bupropion (Forfivo, Wellbutrin, Zyban, ena); calcium blockers monga diltiazem (Cardizem, Cartia, Diltzac, ena), felodipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab, Procardia), ndi verapamil (Calan, Verelan, ku Tarka); carbamazepine (Carbatrol, Equetro, Tegretol, ena); cidofovir; cyclosporine (Gengraf, Neoral, Sandimmune); ganciclovir (cytovene); glecaprevir / pibrentasvir (Mavynet); itraconazole (Sporanox, Onmel); ketoconazole; ledipasvir / sofosbuvir (Harvoni); mankhwala a macrolide monga clarithromycin (Biaxin, mu Prevpac); methadone (Dolophine, Methadose); phenobarbital; phenytoin (Dilantin, mu Phenytek); posaconazole (Noxafil); pravastatin (Pravachol); rifabutin (Mycobutin); rifampin (Rimactane, ku Rifamate, Rifater); mankhwala opatsirana (Zoloft); simeprevir (Olyslo); simvastatin (Flolopid, Zocor, ku Vytorin); mankhwala (Rapamune); sofosbuvir / velpatasvir (Epculsa); sofosbuvir / velpatasvir / voxilaprevir (Vosevi); sorbitol kapena mankhwala omwe amatsekemera ndi sorbitol; tacrolimus (Astagraf, Envarsus, Prograf); trimethoprim (Primsol, ku Bactrim, Septra); valacyclovir (Valtrex); valganciclovir (Valcyte); ndi warfarin (Coumadin, Jantoven). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi efavirenz, lamivudine ndi tenofovir, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
  • auzeni adotolo ngati muli ndi zina mwazomwe zatchulidwa mgawo la CHENJEZO LOFUNIKA, kapena ngati mwakhala ndi nthawi yayitali ya QT (vuto losowa mtima lomwe lingayambitse kugunda kwamtima, kukomoka, kapena kufa mwadzidzidzi), potaziyamu kapena magnesium m'magazi anu, mavuto am'mafupa kuphatikiza kufooka kwa mafupa (vuto lomwe mafupa amafooka ndi kufooka ndikuphwanya mosavuta) kapena kuphwanya kwa mafupa, khunyu, chiwindi C kapena matenda ena a chiwindi, kapena matenda a impso.Komanso muuzeni dokotala ngati mumamwa kapena mumamwa mowa wambiri, kumwa kapena kugwiritsa ntchito mankhwala osokoneza bongo, kumwa mopitirira muyeso kapena kumwa mankhwala osokoneza bongo, kapena mwakhala mukuvutika maganizo kapena matenda ena amisala. Kwa ana omwe amamwa mankhwalawa, uzani dokotala ngati adadwalapo kapena adakhalapo ndi kapamba kapena adalandirapo mankhwala ndi mankhwala a nucleoside analog monga NRTI m'mbuyomu.
  • Uzani dokotala wanu ngati muli ndi pakati, kapena konzekerani kutenga pakati. Simuyenera kutenga pakati mukamalandira chithandizo. Ngati mutha kukhala ndi pakati, muyenera kukhala ndi mayeso olakwika musanatenge mankhwalawa ndikugwiritsa ntchito njira yolerera panthawi yachipatala. Efavirenz, lamivudine, ndi tenofovir zingasokoneze zochita za njira zolerera za mahomoni (mapiritsi oletsa kubala, zigamba, mphete, zopangira, kapena jakisoni), chifukwa chake simuyenera kugwiritsa ntchito njirayi yokhayo yolerera panthawi yachipatala. Muyenera kugwiritsa ntchito njira yoletsa kulera pamodzi ndi njira ina iliyonse yolerera yomwe mwasankha mukamalandira chithandizo komanso kwa milungu 12 mutalandira mankhwala omaliza. Funsani dokotala wanu kuti akuthandizeni kusankha njira yolerera yomwe ingakuthandizeni. Mukakhala ndi pakati mukatenga efavirenz, lamivudine, ndi tenofovir, itanani dokotala wanu mwachangu.
  • simuyenera kuyamwa ngati muli ndi kachilombo ka HIV kapena mukumwa efavirenz, lamivudine, ndi tenofovir.
  • muyenera kudziwa kuti mafuta anu amthupi amatha kuchuluka kapena kusunthira mbali zosiyanasiyana za thupi lanu, monga msana wanu wam'mwamba, khosi ('' njati hump ''), mabere, komanso mozungulira m'mimba mwanu. Mutha kuwona kutaya mafuta m'thupi, kumaso, miyendo, ndi mikono.
  • muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu kapena amayambitsa zina. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa kapena mikhalidwe. Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka mukamamwa mankhwala a efavirenz, lamivudine, ndi tenofovir onetsetsani kuti mwauza dokotala wanu.
  • muyenera kudziwa kuti efavirenz, lamivudine, ndi tenofovir zimatha kukupangitsani kukhala ozunguzika, kugona, osatha kusinkhasinkha, kukhala ndi tulo tofa nato kapena kugona tulo, kukhala ndi maloto achilendo kapena kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe) Zotsatirazi nthawi zambiri zimatha milungu iwiri kapena inayi mutayamba kulandira chithandizo. Zotsatirazi zitha kukhala zoyipa mukamamwa mowa, kapena kumwa mankhwala ena monga kuponderezana, mankhwala a nkhawa, mankhwala amisala, mankhwala ogwidwa, mankhwala opatsirana, mapiritsi ogona, kapena opewetsa nkhawa. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
  • muyenera kudziwa kuti efavirenz, lamivudine, ndi tenofovir zimatha kusintha malingaliro anu, machitidwe anu, kapena thanzi lanu. Itanani dokotala wanu nthawi yomweyo mukakhala ndi zizindikiro izi mukamamwa efavirenz, lamivudine ndi tenofovir: kukhumudwa, kuganiza zodzipha kapena kukonzekera kapena kuyesa kutero, kukwiya kapena kuchita nkhanza, kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe amachita kulibeko), malingaliro achilendo, kusakhudzana ndi zenizeni, kapena kusakhoza kuyenda kapena kuyankhula bwinobwino. Onetsetsani kuti banja lanu likudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati simungathe kupeza chithandizo chanokha.
  • Muyenera kudziwa kuti efavirenz imatha kubweretsa mavuto amanjenje, kuphatikizapo encephalopathy (matenda owopsa omwe amatha kupha ubongo) miyezi kapena zaka mutangotenga efavirenz, lamivudine, ndi tenofovir. Ngakhale mavuto amanjenje amatha kuyamba mutamwa efavirenz, lamivudine, ndi tenofovir kwakanthawi, ndikofunikira kuti inu ndi dokotala muzindikire kuti atha kuyambitsidwa ndi efavirenz. Itanani dokotala wanu nthawi yomweyo ngati mukukumana ndi mavuto moyenera kapena molumikizana, kusokonezeka, mavuto akumbukiro, ndi zovuta zina zomwe zimadza chifukwa cha magwiridwe antchito aubongo, nthawi iliyonse mukamamwa mankhwala a efavirenz, lamivudine, ndi tenofovir. Dokotala wanu angakuuzeni kuti musiye kumwa efavirenz, lamivudine, ndi tenofovir.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Efavirenz, lamivudine, ndi tenofovir zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • mutu
  • kupweteka m'mimba
  • kutsegula m'mimba
  • kutentha pa chifuwa
  • nseru
  • kusanza
  • msana, kulumikizana, kapena kupweteka kwa minofu
  • kusowa mphamvu
  • kuluma, kuwotcha, kapena kumva kupweteka m'manja kapena m'miyendo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zili mgulu la ZOCHITIKA ZOKHUDZA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

  • ming'oma, kupuma movutikira kapena kumeza, kutupa kwa nkhope, mmero, lilime, milomo, kapena maso, kuwuma
  • kutupa, khungu kapena khungu lotupa, kuyabwa, malungo, kutupa kwa nkhope, zilonda mkamwa, maso ofiira kapena otupa
  • kupweteka kwa mitsempha yachilendo, kupuma movutikira, kupweteka m'mimba, nseru, kusanza, kumva kuzizira makamaka m'manja kapena m'miyendo, kumva chizungulire kapena mutu wopepuka, kutopa kwambiri kapena kufooka, kugunda kwamtima kapena kosasinthasintha
  • chikasu cha khungu kapena maso, mkodzo wakuda, ndowe zowala, nseru, kusanza, kusowa kwa njala, kupweteka, kupweteka, kapena kukoma mtima kumtunda chakumanja kwa m'mimba, kutupa m'mimba, kutopa kwambiri, kufooka, kusokonezeka
  • kuchepa kukodza, kutupa kwa miyendo
  • kupweteka kwa mafupa, kupweteka m'manja kapena miyendo, kuphwanya kwa mafupa, kupweteka kwa minofu kapena kufooka, kupweteka kwa mafupa
  • kugwidwa
  • kumverera kukomoka, mutu wopepuka, kapena chizungulire; kugunda kosasinthasintha kapena kofulumira
  • kupweteka kosalekeza komwe kumayambira kumtunda kumanzere kapena pakati pamimba koma kumafalikira kumbuyo, nseru, kusanza

Efavirenz, lamivudine, ndi tenofovir zimatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

  • chizungulire
  • zovuta kulingalira
  • kugona
  • kuvuta kugona kapena kugona
  • maloto achilendo
  • kuwona kapena kumva zinthu zomwe kulibe
  • kusuntha kwa minofu kapena kugwedezeka komwe simungathe kulamulira

Musanayezetsedwe kwa labotale, uzani adotolo ndi ogwira nawo ntchito kuti mukumwa efavirenz, lamivudine, ndi tenofovir.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Khalani ndi efavirenz, lamivudine, ndi tenofovir m'manja. Musayembekezere mpaka mutatsala pang'ono kumwa mankhwala kuti mudzaze mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Symfi®
  • Symfi Lo®
  • EFV, 3TC ndi TDF
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