Jekeseni wa Bamlanivimab

Zamkati

• Asanalandire bamlanivimab,
• Bamlanivimab amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zili mgulu la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi.

Pa Epulo 16, 2021, US Food and Drug Administration idathetsa Emergency Use Authorization (EUA) ya jekeseni ya bamlanivimab yogwiritsa ntchito yokha pochiza matenda a coronavirus 2019 (COVID-19) oyambitsidwa ndi kachilombo ka SARS-CoV-2. Chifukwa chakuchulukirachulukira kwa ma virus a SARS-CoV-2 omwe sakugwiritsa ntchito bamlanivimab okha, a FDA aganiza kuti zabwino zogwiritsa ntchito mankhwalawa sizithandizidwanso. Komabe, jakisoni wa bamlanivimab kuphatikiza jakisoni wa etesevimab akupitilizabe kuvomerezedwa ndi EUA yothandizira COVID-19.

Jekeseni wa Bamlanivimab pano ukuphunziridwa pochiza matenda a coronavirus 2019 (COVID-19) oyambitsidwa ndi kachilombo ka SARS-CoV-2.

Zambiri pazoyeserera zamankhwala zomwe zilipo pakadali pano zothandizira kugwiritsa ntchito bamlanivimab pochiza COVID-19. Zambiri zimafunikira kuti mudziwe momwe bamlanivimab amagwirira ntchito pochiza COVID-19 komanso zovuta zomwe zingachitike.

Jekeseni wa Bamlanivimab sanapezenso kuwunika kovomerezeka kuti kuvomerezedwe ndi FDA kuti agwiritse ntchito.Komabe, a FDA adavomereza Chilolezo Chogwiritsa Ntchito Mwadzidzidzi (EUA) kuti alole achikulire ena omwe sanalandire chipatala ndi ana azaka 12 kapena kupitilira omwe ali ndi zizindikiro zochepa za COVID-19 kuti alandire jekeseni la bamlanivimab.

Lankhulani ndi dokotala wanu za kuopsa ndi ubwino wolandira mankhwalawa.

Jekeseni wa Bamlanivimab amagwiritsidwa ntchito pochiza matenda a COVID-19 mwa anthu ena osagonekedwa mchipatala ndi ana azaka 12 zakubadwa kapena kupitilira apo omwe amalemera pafupifupi 40 kg (40 kg) komanso omwe ali ndi zizindikiro zochepa za COVID-19. Amagwiritsidwa ntchito kwa anthu omwe ali ndi zovuta zina zamankhwala zomwe zimawapangitsa kuti akhale pachiwopsezo chachikulu chokhala ndi zisonyezo zazikulu za COVID-19 kapena kufunika kogonekedwa mchipatala kuchokera ku matenda a COVID-19. Bamlanivimab ali mgulu la mankhwala otchedwa monoclonal antibodies. Zimagwira ntchito poletsa kuchita zinthu zina zachilengedwe m'thupi kuti zithetse kufalikira kwa kachilomboka.

Bamlanivimab amabwera ngati yankho (madzi) kuti asakanikidwe ndi madzi ndikubayidwa pang'onopang'ono mumtsinje kwa mphindi 60 ndi dokotala kapena namwino. Amapatsidwa ngati nthawi imodzi posachedwa atayesedwa bwino kwa COVID-19 ndipo pasanathe masiku 10 kuchokera pomwe matenda a COVID-19 ayamba monga malungo, chifuwa, kapena kupuma pang'ono.

Kubaya kwa Bamlanivimab kumatha kubweretsa zovuta kapena zoopsa pamoyo wamankhwalawo atatha. Dokotala kapena namwino adzakuyang'anirani mosamala mukalandira mankhwalawa komanso kwa ola limodzi mutalandira. Uzani dokotala wanu kapena namwino nthawi yomweyo ngati mukukumana ndi izi mwa izi: kuzizira; nseru; mutu; kupuma movutikira; kuthamanga kapena kuthamanga kwa magazi; kugunda pang'onopang'ono kapena mwachangu; kupweteka pachifuwa kapena kusapeza bwino; kufooka; chisokonezo; kutopa; kupuma; zidzolo, ming'oma, kapena kuyabwa; kupweteka kwa minofu kapena kupweteka; chizungulire; thukuta; kapena kutupa kwa nkhope, mmero, lilime, kapena milomo. Dokotala wanu angafunikire kuchepetsa kulowetsedwa kwanu kapena kusiya chithandizo chanu mukakumana ndi zina mwa zotsatirazi.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire bamlanivimab,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi bamlanivimab, mankhwala aliwonse, kapena chilichonse chomwe chingaphatikizidwe mu jakisoni wa bamlanivimab. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala osagwiritsa ntchito chitetezo chamankhwala monga cyclosporine (Gengraf, Neoral, Sandimmune), prednisone, ndi tacrolimus (Astagraf, Envarsus, Prograf). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni dokotala ngati mwakhalapo kapena munakhalapo ndi matenda aliwonse.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukalandira bamlanivimab, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Bamlanivimab amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kutuluka magazi, mabala, kupweteka, kupweteka, kapena kutupa pamalo obayira

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zili mgulu la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi.

• malungo
• kuvuta kupuma
• kusintha kwa kugunda kwa mtima
• kutopa kapena kufooka
• chisokonezo

Jekeseni wa Bamlanivimab imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani maimidwe onse ndi dokotala wanu.

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudza jekeseni wa bamlanivimab.

Muyenera kupitiriza kudzipatula monga adanenera dokotala ndikutsatira njira zathanzi monga kuvala chophimba kumaso, kusayenda pagulu, komanso kusamba m'manja pafupipafupi.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

American Society of Health-System Pharmacists, Inc. ikuyimira kuti izi zokhudza bamlanivimab zidapangidwa ndi chisamaliro choyenera, komanso mogwirizana ndi miyezo yaukadaulo pamunda. Owerenga akuchenjezedwa kuti bamlanivimab si chithandizo chovomerezeka cha matenda a coronavirus 2019 (COVID-19) yoyambitsidwa ndi SARS-CoV-2, koma, ikufufuzidwa ndipo ikupezeka pansi pake, chilolezo chogwiritsa ntchito mwadzidzidzi cha FDA (EUA) kwa chithandizo cha COVID-19 wofatsa pang'ono kapena pang'ono. American Society of Health-System Pharmacists, Inc. sipanga zisonyezero kapena zitsimikizo, kufotokoza kapena kutanthawuza, kuphatikiza, koma kutha, chitsimikizo chilichonse chokhudzana ndi kugulitsika komanso / kapena kukhala ndi thanzi labwino pazolinga zina, mokhudzana ndi zambiri, makamaka imatulutsa zitsimikizo zonsezi. Owerenga za bamlanivimab akulangizidwa kuti ASHP siyomwe imayambitsa ndalama zomwe zimapitilizidwa, pazolakwitsa zilizonse kapena kusiyidwa, komanso / kapena zovuta zilizonse zomwe zingabwere chifukwa chogwiritsa ntchito izi. Owerenga amalangizidwa kuti zisankho zokhudzana ndi mankhwala ndizovuta kusankha zamankhwala zomwe zimafunikira ufulu wodziyimira pawokha, wodziwa za akatswiri oyenera azaumoyo, ndipo zomwe zili munkhaniyi zimaperekedwa kuti zidziwitse okha. American Society of Health-System Pharmacists, Inc. sivomereza kapena kuvomereza kugwiritsa ntchito mankhwala aliwonse. Izi zokhudza bamlanivimab sizoyenera kuwerengedwa ngati upangiri wa odwala. Chifukwa cha kusintha kwa chidziwitso cha mankhwala, mukukulangizidwa kuti mufunsane ndi dokotala kapena wamankhwala za momwe mungagwiritsire ntchito mankhwala aliwonse.

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