Bamlanivimab ndi Etesevimab jekeseni

Zamkati

• Asanalandire bamlanivimab ndi jakisoni wa etesevimab,
• Bamlanivimab ndi jakisoni wa etesevimab angayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa m'gawo la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

Kuphatikiza kwa bamlanivimab ndi jakisoni wa etesevimab akuwerengedwa pakadali pano pochiza matenda a coronavirus 2019 (COVID-19) oyambitsidwa ndi kachilombo ka SARS-CoV-2.

Zidziwitso zochepa zokha zoyeserera zamankhwala zomwe zilipo pakadali pano zothandizira kugwiritsa ntchito bamlanivimab ndi etesevimab pochiza COVID-19. Zambiri zimafunikira kuti mudziwe momwe bamlanivimab ndi etesevimab amagwirira ntchito pochiza COVID-19 komanso zovuta zomwe zingachitike.

Kuphatikiza kwa bamlanivimab ndi etesevimab sikunayambebe kuwunikiridwa kovomerezeka kuti kuvomerezedwe ndi a FDA kuti agwiritse ntchito. Komabe, a FDA avomereza Chilolezo Chogwiritsa Ntchito Mwadzidzidzi (EUA) kuti alole achikulire ena omwe sanalandire chipatala ndi ana azaka 12 kapena kupitilira omwe ali ndi zizindikiro zochepa za COVID-19 kuti alandire jekeseni wa bamlanivimab ndi etesevimab.

Kuphatikiza kwa bamlanivimab ndi jakisoni wa etesevimab amagwiritsidwa ntchito pochiza matenda a COVID-19 mwa anthu ena osagonekedwa mchipatala ndi ana azaka 12 zakubadwa kapena kupitilira omwe amalemera mapaundi 88 (40 kg) komanso omwe ali ndi zizindikiro zochepa za COVID-19. Amagwiritsidwa ntchito kwa anthu omwe ali ndi matenda ena monga matenda ashuga, matenda opatsirana pogonana, kapena impso, mtima, kapena matenda am'mapapo omwe amawaika pachiwopsezo chachikulu chokhala ndi zisonyezo zazikulu za COVID-19 komanso / kapena ofuna kupita kuchipatala kuchokera ku COVID-19. Bamlanivimab ndi etesevimab ali m'kalasi lotchedwa ma monoclonal antibodies. Mankhwalawa amagwira ntchito poletsa kuchitapo kanthu kwachilengedwe m'thupi kuti athetse kufalikira kwa kachilomboka.

Bamlanivimab ndi etesevimab amadza ngati zothetsera (zamadzimadzi) kuti azisakanikirana ndi madzi owonjezera ndikubayidwa pang'onopang'ono mumitsempha ndi dokotala kapena namwino. Amapatsidwa limodzi ngati gawo limodzi nthawi yomweyo atayesedwa bwino kwa COVID-19 ndipo pasanathe masiku 10 kuchokera pomwe matenda a COVID-19 ayamba monga malungo, chifuwa, kapena kupuma pang'ono.

Kuphatikiza kwa bamlanivimab ndi jakisoni wa etesevimab kumatha kubweretsa zovuta kapena zoopsa pamoyo pakulowetsedwa komanso pambuyo pake. Dokotala kapena namwino adzakuyang'anirani mosamala mukalandira mankhwalawa komanso kwa ola limodzi mutalandira. Uzani dokotala wanu kapena namwino nthawi yomweyo mukakumana ndi izi: kutentha thupi, kupuma movutikira, kuzizira, kutopa, kupweteka pachifuwa, kusapeza bwino pachifuwa, kufooka, kusokonezeka, nseru, kupweteka mutu, kupuma movutikira, kupuma, kukhosi Kupsa mtima, zidzolo, ming'oma, kuyabwa, kuthamanga, kupweteka kwa minofu kapena chizungulire, makamaka mukaimirira, kutuluka thukuta, kapena kutupa kwa nkhope, mmero, lilime, milomo, kapena maso. Dokotala wanu angafunikire kuchepetsa kulowetsedwa kwanu kapena kusiya chithandizo chanu mukakumana ndi zina mwa zotsatirazi.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire bamlanivimab ndi jakisoni wa etesevimab,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi bamlanivimab, etesevimab, mankhwala ena aliwonse, kapena zosakaniza zilizonse za bamlanivimab ndi jakisoni wa etesevimab. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala osagwiritsa ntchito chitetezo chamankhwala monga cyclosporine (Gengraf, Neoral, Sandimmune), prednisone, ndi tacrolimus (Astagraf, Envarsus, Prograf). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni dokotala ngati mwakhalapo kapena munakhalapo ndi matenda aliwonse.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukalandira jekeseni wa bamlanivimab ndi etesevimab, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Bamlanivimab ndi jakisoni wa etesevimab angayambitse zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutuluka magazi, mabala, kupweteka, kupweteka, kapena kutupa pamalo obayira

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa m'gawo la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

• malungo, kupuma movutikira, kusintha kwa kugunda kwa mtima, kutopa, kufooka, kapena kusokonezeka

Bamlanivimab ndi jakisoni wa etesevimab angayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudza bamlanivimab ndi jakisoni wa etesevimab.

Muyenera kupitiriza kudzipatula monga adanenera adotolo ndikutsatira njira zathanzi monga kuvala mask, kusayenda pagulu, komanso kusamba m'manja pafupipafupi.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

American Society of Health-System Pharmacists, Inc. ikuyimira kuti chidziwitso chokhudza bamlanivimab ndi etesevimab chidapangidwa ndi chisamaliro choyenera, komanso mogwirizana ndi miyezo yaukadaulo pamunda. Owerenga akuchenjezedwa kuti bamlanivimab ndi etesevimab si mankhwala ovomerezeka a matenda a coronavirus 2019 (COVID-19) oyambitsidwa ndi SARS-CoV-2, koma, akufufuzidwa ndipo akupezeka pano, chilolezo chogwiritsa ntchito mwadzidzidzi cha FDA (EUA) zochizira COVID-19 wofatsa pang'ono kapena pang'ono. American Society of Health-System Pharmacists, Inc. sipanga zisonyezero kapena zitsimikizo, kufotokoza kapena kutanthawuza, kuphatikiza, koma kutha, chitsimikizo chilichonse chokhudzana ndi kugulitsika komanso / kapena kukhala ndi thanzi labwino pazolinga zina, mokhudzana ndi zambiri, makamaka imatulutsa zitsimikizo zonsezi. Owerenga za bamlanivimab ndi etesevimab amalangizidwa kuti ASHP siyomwe imayambitsa ndalama zomwe zimapitilizidwa, pazolakwitsa zilizonse, kapena / kapena pazotsatira zilizonse zomwe zingabwere chifukwa chogwiritsa ntchito izi. Owerenga amalangizidwa kuti zisankho zokhudzana ndi mankhwala ndizovuta kusankha zamankhwala zomwe zimafunikira ufulu wodziyimira pawokha, wodziwa za akatswiri oyenera azaumoyo, ndipo zomwe zili munkhaniyi zimaperekedwa kuti zidziwitse okha. American Society of Health-System Pharmacists, Inc. sivomereza kapena kuvomereza kugwiritsa ntchito mankhwala aliwonse. Izi zokhudza bamlanivimab ndi etesevimab siziyenera kutengedwa ngati upangiri wa odwala. Chifukwa cha kusintha kwa chidziwitso cha mankhwala, mukukulangizidwa kuti mufunsane ndi dokotala kapena wamankhwala za momwe mungagwiritsire ntchito mankhwala aliwonse.