Carbamazepine

Zamkati

• Musanatenge carbamazepine,
• Carbamazepine angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mgawo LOFUNIKA KUCHENJEZA NDI CHITSANZO, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo izi:

Carbamazepine imatha kuyambitsa matenda omwe amatchedwa Stevens-Johnson syndrome (SJS) kapena poizoni wa epidermal necrolysis (TEN). Izi zimapangitsa kuti khungu ndi ziwalo zamkati ziwonongeke kwambiri. Chiwopsezo cha SJS kapena TEN chimakhala chachikulu kwambiri mwa anthu ochokera ku Asia omwe ali ndi vuto lobadwa nalo. Ngati ndinu waku Asia, dokotala wanu nthawi zambiri amayitanitsa mayeso kuti awone ngati muli ndi chiopsezo cha majini musanapereke mankhwala a carbamazepine. Ngati mulibe chiopsezo chotengera chibadwa ichi, dokotala akhoza kukupatsani carbamazepine, komabe pali chiopsezo chochepa choti mungakhale ndi SJS kapena TEN. Itanani dokotala wanu nthawi yomweyo mukayamba kuphulika, ming'oma, kuphulika kapena khungu, kupweteketsa, zilonda mkamwa, kapena malungo mukamalandira carbamazepine. Matenda a Stevens-Johnson kapena poizoni epidermal necrolysis nthawi zambiri amapezeka miyezi ingapo yoyambirira ya mankhwala ndi carbamazepine.

Carbamazepine ikhoza kuchepetsa kuchuluka kwa maselo amwazi wopangidwa ndi thupi lanu. Nthawi zambiri, kuchuluka kwama cell am'magazi kumatha kutsika kokwanira kupangitsa mavuto azaumoyo kapena owopsa. Uzani dokotala wanu ngati mudakhalapo ndi vuto lamafupa (kuchepa kwa maselo amwazi) kapena matenda ena aliwonse amwazi, makamaka ngati adayambitsidwa ndi mankhwala ena. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: zilonda zapakhosi, malungo, kuzizira, kapena zizindikilo zina zamatenda omwe amabwera ndikutha kapena osatha; kupuma movutikira; kutopa; kutuluka mwachilendo kapena kuvulaza monga kutuluka magazi msambo, kutuluka magazi m'mphuno, kapena m'kamwa; madontho ofiira kapena ofiirira pakhungu; kapena zilonda za mkamwa ..

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira ku carbamazepine.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi carbamazepine ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) kapena tsamba laopanga kuti mupeze Chithandizo cha Mankhwala.

Carbamazepine imagwiritsidwa ntchito yokha kapena kuphatikiza mankhwala ena kuti athetse mitundu ina ya khunyu mwa anthu omwe ali ndi khunyu. Amagwiritsidwanso ntchito pochiza trigeminal neuralgia (zomwe zimayambitsa kupweteka kwa nkhope). Ma carbamazepine omwe amatulutsa makapisozi (Equetro brand okha) amagwiritsidwanso ntchito kuthana ndi ma mania (okwiya, okhumudwa kapena osakwiya) kapena magawo osakanikirana (zizindikilo za mania ndi kukhumudwa zomwe zimachitika nthawi yomweyo) kwa odwala omwe ali ndi matenda a bipolar I disorder ( Matenda a manic-depression; matenda omwe amayambitsa magawo okhumudwa, magawo amanjenje, ndimikhalidwe zina zosazolowereka). Carbamazepine ali mgulu la mankhwala otchedwa anticonvulsants. Zimagwira ntchito pochepetsa magwiridwe antchito amagetsi muubongo.

Carbamazepine amabwera ngati piritsi, piritsi losavuta, piritsi lotulutsa nthawi yayitali, kapisozi womasulidwa, komanso kuyimitsidwa (madzi) kutenga pakamwa. Piritsi lokhazikika, piritsi losavuta kudya, ndi kuyimitsa nthawi zambiri amatengedwa kawiri kapena kanayi patsiku ndikudya. Piritsi lotulutsa (Tegretol XR) nthawi zambiri limatengedwa kawiri patsiku ndikudya. Capsule yotulutsidwa yochulukirapo (Carbatrol, Equetro) nthawi zambiri imamwedwa kawiri patsiku kapena osadya. Kukuthandizani kukumbukira kukumbukira kutenga carbamazepine, tengani mozungulira nthawi imodzimodzi tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani carbamazepine ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi otulutsidwa otalikiratu; osagawana, kutafuna, kapena kuwaphwanya. Makapisozi otulutsidwa nthawi yayitali amatha kutsegulidwa ndipo mikanda mkati mwake imakonkhedwa pa chakudya, monga supuni ya tiyi ya maapulo kapena chakudya chofananira. Osaphwanya kapena kutafuna makapisozi otulutsidwa kapena mikanda mkati mwake.

Sambani kuyimitsidwa bwino musanagwiritse ntchito kusakaniza mankhwala mofanana.

Dokotala wanu akuyambitsani pa carbamazepine yochepa ndipo pang'onopang'ono mukulitse mlingo wanu.

Carbamazepine itha kuthandizira kuwongolera matenda anu koma sangachiritse. Zitha kutenga milungu ingapo kapena kupitilira apo kuti mumve bwino carbamazepine. Pitirizani kumwa carbamazepine ngakhale mukumva bwino. Osasiya kumwa carbamazepine osalankhula ndi dokotala, ngakhale mutakhala ndi zovuta monga kusintha kosasintha kwamakhalidwe kapena malingaliro. Ngati muli ndi matenda okomoka ndipo mwadzidzidzi mukusiya kumwa carbamazepine, kugwa kwanu kumatha kukulirakulira. Dokotala wanu mwina amachepetsa mlingo wanu pang'onopang'ono.

Carbamazepine nthawi zina amagwiritsidwanso ntchito kuthana ndi matenda amisala, kukhumudwa, kusokonezeka kwa m'maganizo, kusiya kumwa mankhwala osokoneza bongo ndi mowa, matenda osapumira a miyendo, matenda a shuga insipidus, ma syndromes ena opweteka, ndi matenda mwa ana otchedwa chorea. Lankhulani ndi dokotala wanu za kuopsa kokugwiritsa ntchito mankhwalawa.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge carbamazepine,

• uzani adotolo ndi wazamankhwala ngati muli ndi ziwengo (zotupa, zopumira, ming'oma, zovuta kumeza kapena kupuma, kutupa kwa nkhope yanu, maso, zikope, milomo, kapena lilime) ku carbamazepine, amitriptyline (Elavil), amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor, Zonalon), imipramine (Tofranil), nortriptyline (Pamelor), oxcarbazepine (Trileptal), protriptyline (Vivactil), mankhwala ena ogwidwa monga phenobarbital, phenytoin (Dilantin, Mysoline), mankhwala ena aliwonse, kapena zosakaniza zilizonse za kukonzekera kwa carbamazepine. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• uzani dokotala ngati mukumwa nefazadone kapena non-nucleoside reverse transcriptase inhibitors (NNRTIs) monga delavirdine (Rescriptor). Dokotala wanu angakuuzeni kuti musamwe carbamazepine ndi mankhwalawa. Komanso, uzani dokotala ngati mukumwa monoamine oxidase (MAO) inhibitor monga isocarboxazid (Marplan), linezolid (Zyvox), methylene buluu, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ndi tranylcypromine (Parnate) , kapena ngati mwasiya kumwa MAO inhibitor m'masiku 14 apitawa. Dokotala wanu angakuuzeni kuti musatenge carbamazepine. Mukasiya kumwa carbamazepine, muyenera kudikirira masiku osachepera 14 musanayambe kumwa MAO inhibitor.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: acetaminophen (Tylenol); acetazolamide (Diamox); albendazole (Albenza); alprazolam (Panax); aminophylline; anticoagulants ('blood thinners') monga apixaban (Eliquis), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban powder (Xarelto), ndi warfarin (Coumadin, Jantoven); antidepressants monga amitriptyline (Elavil), bupropion (Wellbutrin, Zyban), buspirone (BuSpar), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvoapine) ), nortriptyline (Pamelor); antifungals monga fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, ndi voriconazole (Vfend); Aprepitant (Emend); aripiprazole (Limbikitsani); buprenorphine (Butrans, Sublocade); bupropion (Aplenzin, Wellbutrin, Zyban); cimetidine (Tagamet); ciprofloxacin; cisplatin (Platinol); corticosteroids monga dexamethasone ndi prednisolone (Prelone); clarithromycin (Biaxin, mu Prevpac); clonazepam (Klonopin); clozapine (Clozaril); cyclophosphamide; cyclosporine (Gengraf, Neoral, Sandimmune); dalfopristin ndi quinupristin (Synercid); danazol (Danocrine); dantrolene (Dantrium); diltiazem (Cardizem, Diltzac, Tiazac, ena); okodzetsa (mapiritsi amadzi); doxorubicin (Adriamycin, Rubex); doxycycline (Vibramycin); erythromycin (EES, E-Mycin, Erythrocin); eslicarbazepine (Aptiom); everolimus (Wothandizira, Zortress); felodipine (Kukongola); haloperidol (Haldol); HIV protease inhibitors kuphatikiza atazanavir (Reyataz), indinavir (Crixivan), lopinavir (ku Kaletra), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Fortovase, Invirase); ibuprofen (Advil); imatinib (Gleevec); isoniazid (INH, Laniazid, ku Rifater); levothyroxine (Levoxyl, Synthroid); lifiyamu (Lithobid); loratadine (Claritin); lorazepam (Ativan); loxapine (Adasuve); mankhwala ena ochizira malungo monga chloroquine (Aralen) ndi mefloquine; mankhwala a nkhawa kapena matenda amisala; mankhwala ena ogwidwa monga ethosuximide (Zarontin), felbamate (Felbatol), fosphenytoin (Cerebyx); lamotrigine (Lamictal), methsuximide (Celontin), oxcarbazepine (Trileptal), phenobarbital, phensuximide (Milontin) (sakupezeka ku US), phenytoin (Dilantin, Phenytek), primidone (Mysoline), tiagabine (Gabitrilama), topiramate , ndi valproic acid (Depakene, Depakote); lapatinib; methadone (Dolophine, Methadose); masewera; niacinamide (nicotinamide, Vitamini B3); olanzapine; omeprazole; mpweya; chotsitsa (Darvon); praziquantel (Biltricide); quetiapine; quinine; rifampin (Rifadin, Rimactane); mankhwala; mankhwala ogonetsa; mankhwala opatsirana (Zoloft); sirolimus; mapiritsi ogona; tacrolimus (Prograf); tadalafil (Adcirca, Cialis); temsirolimus (Torisel); terfenadine (Seldane) (sikupezeka ku US); theophylline (Theo-24, Theochron, ena); ticlopidine; tramadol (Ultram); zotetezera; trazodone; troleandomycin (TAO); verapamil (Calan, Verelan); zileuton (Zyflo); ziprasidone (Geodon), ndi zonisamide (Zonegran). Mankhwala ena ambiri amathanso kulumikizana ndi carbamazepine, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa mankhwala ena aliwonse amadzimadzi, musamamwe nthawi yomweyo kuyimitsidwa kwa carbamazepine.
• auzeni adotolo ngati mwakhala mukudwala matenda a glaucoma (vuto lomwe kuchuluka kwa diso kumatha kubweretsa kutaya kwamaso pang'onopang'ono); kapena matenda a mtima, impso, chithokomiro, kapena chiwindi.
• muyenera kudziwa kuti carbamazepine imatha kuchepetsa mphamvu yolera yolerera (mapiritsi oletsa kubala, zigamba, mphete, jakisoni, zopangira, kapena zida za intrauterine). Gwiritsani ntchito njira ina yolerera mukamamwa carbamazepine. Uzani dokotala wanu ngati muli ndi magazi mwadzidzidzi m'mimba kapena mukuganiza kuti mutha kukhala ndi pakati mukatenga carbamazepine.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Carbamazepine atha kuvulaza mwana wosabadwayo. Mukakhala ndi pakati mukatenga carbamazepine, itanani dokotala wanu mwachangu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa carbamazepine.
• muyenera kudziwa kuti carbamazepine imatha kukupangitsani kugona. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• kumbukirani kuti mowa umatha kuwonjezera ku tulo chifukwa cha mankhwalawa.
• muyenera kudziwa kuti thanzi lanu lingasinthe m'njira zosayembekezereka ndipo mutha kudzipha (kuganiza zodzipweteka kapena kudzipha nokha kapena kukonzekera kapena kuyesa kutero) mukamamwa carbamazepine pochiza khunyu, matenda amisala, kapena zina. Chiwerengero chochepa cha achikulire ndi ana azaka 5 zakubadwa kapena kupitilira (pafupifupi 1 mwa anthu 500) omwe adatenga ma anticonvulsants monga carbamazepine kuti athetse mavuto osiyanasiyana panthawi yamaphunziro azachipatala adadzipha panthawi yomwe amathandizidwa. Ena mwa anthuwa adayamba kudzipha sabata limodzi atayamba kumwa mankhwalawo. Pali chiopsezo kuti mutha kusintha kusintha kwaumoyo wanu ngati mutamwa mankhwala a anticonvulsant monga carbamazepine, koma pakhoza kukhala pachiwopsezo kuti musinthe thanzi lanu lamankhwala ngati matenda anu sakuchiritsidwa. Inu ndi dokotala wanu muwona ngati kuopsa kokumwa mankhwala a anticonvulsant ndiokulirapo kuposa kuopsa kosamwa mankhwalawo. Inu, banja lanu, kapena amene amakusamalirani muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: mantha; kusakhazikika kapena kusakhazikika; kukwiya kwatsopano kapena kukulira, nkhawa, kapena kukhumudwa; kuchita zofuna zawo; kuvuta kugona kapena kugona; aukali, aukali, kapena achiwawa; mania (kukwiya, kusangalala modabwitsa); kuyankhula kapena kuganiza zofuna kudzipweteka kapena kudzipha; kudzipatula kwa abwenzi ndi abale; kutanganidwa ndi imfa ndi kufa; kupereka zinthu zamtengo wapatali; kapena kusintha kwina kulikonse pamakhalidwe kapena malingaliro. Onetsetsani kuti banja lanu kapena amene akukusamalirani akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati mukulephera kupeza chithandizo chanokha.
• ngati muli ndi fructose intolerance (mkhalidwe wobadwa nawo momwe thupi limasowa mapuloteni ofunikira kuti awononge fructose [shuga wazipatso wopezeka muzotsekemera zina monga sorbitol], muyenera kudziwa kuti kuyimitsidwa pakamwa kumakoma ndi sorbitol. Uzani dokotala wanu ngati muli ndi tsankho la fructose.

Lankhulani ndi dokotala wanu za kudya zipatso zamtengo wapatali kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Carbamazepine angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• chizungulire
• kuganiza zachilendo
• zovuta kuyankhula
• kugwedezeka kosalamulirika kwa gawo lina la thupi
• kudzimbidwa
• pakamwa pouma

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mgawo LOFUNIKA KUCHENJEZA NDI CHITSANZO, itanani dokotala wanu mwachangu:

• chisokonezo
• zidzolo
• kuthamanga, kuchepa, kapena kugunda kwamtima
• chikasu cha khungu kapena maso
• mkodzo wakuda
• kupweteka kumanja kwa gawo m'mimba mwanu
• kusowa chilakolako
• nseru
• kusanza
• masomphenya amasintha
• kutopa
• kutupa kwa nkhope yanu, maso, zikope, milomo, kapena lilime
• zovuta kumeza kapena kupuma
• kupweteka kwa mutu, kugwa kwatsopano kapena kuchuluka kwa zovuta, kuvutika kuganizira, kusokonezeka, kufooka, kapena kusakhazikika
• Kutupa kwakukulu ndi chimodzi kapena zingapo zotsatirazi: malungo, minofu kapena molumikizana mafupa, maso ofiira kapena otupa, zotupa kapena khungu, khungu zilonda, kapena kutupa kwa nkhope kapena khosi

Carbamazepine angayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha, kutali ndi kuwala, kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kukomoka
• kugwidwa
• kusakhazikika
• kugwedezeka kwa minofu
• kusuntha kosazolowereka
• kugwedeza gawo la thupi lanu lomwe simungathe kulilamulira
• kusakhazikika
• Kusinza
• chizungulire
• masomphenya amasintha
• kupuma kosalekeza kapena kwakanthawi
• kuthamanga kapena kugunda kwamtima
• nseru
• kusanza
• kuvuta kukodza

Musanayesedwe mu labotale, uzani adotolo ndi omwe akuwagwiritsa ntchito kuti mukumwa carbamazepine.

Carbamazepine imatha kusokoneza zotsatira za mayeso apakhomo. Lankhulani ndi dokotala ngati mukuganiza kuti mutha kukhala ndi pakati mukatenga carbamazepine. Musayese kuyesa kutenga mimba kunyumba.

Piritsi lotulutsidwalo silimasungunuka m'mimba mutatha kumeza. Imatulutsa mankhwala pang'onopang'ono ikamadutsa m'thupi lanu. Mutha kuwona zokutira piritsi mu chopondapo chanu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Carbatrol^®
• Epitol^®
• Gulu la Equetro^®
• Tegretol^®
• Tegretol^®-XR