Efavirenz

Zamkati

• Musanayambe kumwa efavirenz,
• Efavirenz ikhoza kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zatchulidwa mgulu la ZOCHITIKA, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo:

Efavirenz imagwiritsidwa ntchito limodzi ndi mankhwala ena kuchiza kachilombo ka HIV. Efavirenz ali mgulu la mankhwala otchedwa non-nucleoside reverse transcriptase inhibitors (NNRTIs). Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka HIV m'magazi. Ngakhale efavirenz sichitha kachilombo ka HIV, imatha kuchepetsa mwayi wanu wopeza matenda a immunodeficiency syndrome (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa pamodzi ndi kugonana mosatekeseka ndikusintha zina pamoyo wanu kumachepetsa chiopsezo chotenga (kufalitsa) kachirombo ka HIV kwa anthu ena.

Efavirenz imabwera ngati kapisozi komanso ngati piritsi yomwe imamwa. Nthawi zambiri amatengedwa kamodzi patsiku ndimadzi ambiri pamimba yopanda kanthu (osachepera ola limodzi musanadye kapena maola awiri mutadya). Imwani efavirenz nthawi yofanana tsiku lililonse. Kutenga efavirenz panthaŵi yogona kungapangitse kuti mavuto ena asakhale ovuta. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani efavirenz ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi ndi makapisozi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Ngati mukulephera kumeza mankhwala onse, mutha kumwa efavirenz posakaniza zomwe zili mu kapisozi ndi zakudya zofewa komanso kudya. Kuti mukonzekere mlingo uliwonse, tsegulitsani kapisozi ndikuwaza zomwe zili mkati mwa ma supuni 1-2 a chakudya chofewa mchidebe chaching'ono. Mutha kugwiritsa ntchito zakudya zofewa monga maapulosi, odzola mphesa, kapena yogurt. Mukakonkha, samalani kuti musataye zomwe zili mu kapisozi, kapena kuziyala mlengalenga. Sakanizani mankhwala ndi chakudya chofewa. Chosakanikacho chiyenera kuwoneka chonyezimira koma sayenera kukhala chotupa. Muyenera kudya mankhwala osakaniza ndi zakudya zofewa pasanathe mphindi 30 kuchokera pamene mwasakaniza. Mukamaliza, onjezerani supuni 2 za chakudya chofewa mu chidebe chopanda kanthu, sakanizani, ndi kudya kuti mutsimikizire kuti mwalandira mankhwala athunthu. Osadya maola awiri otsatira.

Ngati efavirenz ikupatsidwa kwa mwana yemwe sangadyebe zakudya zolimba, zomwe zili mu kapisozi zimatha kusakanizidwa ndi masupuni awiri a firiji yamwana wakhanda muchidebe chaching'ono. Mukamatulutsa kapisozi, samalani kuti musataye zomwe zili mkatimo, kapena kuziyala mlengalenga. Chosakanikacho chiyenera kuwoneka chonyezimira koma sayenera kukhala chotupa. Chosakanikacho chiyenera kulandira syringe kwa mwana mkati mwa mphindi 30 zosakaniza. Mukamaliza, onjezerani supuni 2 zowonjezera za mkaka mu chidebe chopanda kanthu, sakanizani, ndi syringe chakudya kwa mwana kuti mutsimikizire kuti mwamupatsa mankhwala okwanira. Osapereka mankhwala kwa mwana mu botolo. Osamadyetsa mwana kwa maola awiri otsatira.

Efavirenz imayang'anira kachilombo ka HIV, koma siyimachiza. Pitirizani kumwa efavirenz ngakhale mukumva bwino. Osasiya kumwa efavirenz osalankhula ndi dokotala. Efavirenz yanu ikayamba kuchepa, pezani zambiri kuchokera kwa dokotala kapena wamankhwala. Mukaphonya Mlingo kapena kusiya kumwa efavirenz, matenda anu akhoza kukhala ovuta kuchiza.

Efavirenz imagwiritsidwanso ntchito ndi mankhwala ena othandiza kupewa matenda mwa ogwira ntchito zaumoyo kapena anthu ena omwe adapezeka mwangozi mwa kachilombo ka HIV. Lankhulani ndi dokotala wanu za kuopsa kokugwiritsa ntchito mankhwalawa.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanayambe kumwa efavirenz,

• auzeni adotolo komanso asayansi yanu ngati mankhwala ena aliwonse sagwirizana ndi efavirenz, kapena ngati simugwirizana ndi zilizonse zomwe zili m'mapiritsi a efavirenz. Funsani dokotala wanu kapena wamankhwala mndandanda wa zosakaniza.
• muyenera kudziwa kuti efavirenz imapezekanso pophatikiza ndi mankhwala ena omwe ali ndi dzina la Atripla. Uzani dokotala wanu ngati mukumwa mankhwalawa kuti mutsimikizire kuti simulandiranso mankhwala omwewo kawiri.
• uzani dokotala wanu ngati mukumwa elbasvir ndi grazoprevir (Zepatier). Dokotala wanu angakuuzeni kuti musamwe efavirenz ngati mukumwa mankhwalawa.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: antidepressants, artemether ndi lumefantrine (Coartem), atazanavir (Reyataz), atorvastatin (Lipitor, ku Caduet), atovaquone ndi proguanil, bupropion (Wellbutrin, Zyban, ena, ku Contrave), carbamroline (Carbatrol) , Epitol, Equetro, Tegretol, Teril), clarithromycin (Biaxin, ku Prevpac), cyclosporine (Gengraf, Neoral, Sandimmune), delavirdine (Rescriptor), diltiazem (Cardizem CD, Cartia XT, Diltzac, Taztia XT), ethinylrimate (Estarylla, Ortho-Tri-Cyclen, Sprintec, ena), etravirine (Intelence), etonogestrel (Implanon, Nexplanon, Nuvaring), felodipine, fosamprenavir (Lexiva), itraconazole (Sporanox), indinavir (Crixivanrel), levonorgest B sitepe imodzi, Skyla, ku Climera Pro, Seasonale, ena), lopinavir (ku Kaletra), maraviroc (Selzentry), mankhwala a nkhawa, mankhwala a matenda amisala, mankhwala ogwidwa, methadone (Dolophine, Methadose), nevirapine (Viramune) , nicardipine (Cardene), nifedipine (A dalat, Afeditab, Procardia XL), norelgestromin (ku Xulane), phenobarbital, phenytoin (Dilantin, Phenytek), posaconazole (Noxafil), pravastatin (Pravachol), rifabutin (Mycobutin), rifampin (Rifadin, Rifate rilpivirine (Edurant, ku Complera, Odefsey), ritonavir (Norvir, ku Kaletra, Technivie, Viekira), saquinavir (Invirase), mankhwala, sertraline (Zoloft), simeprevir (Olysio), simvastatin (Zocor, ku Vytorin), sirolim ), mapiritsi ogona, tacrolimus (Envarsus XR, Prograf), opewetsa nkhawa, verapamil (Calan, Covera, Verelan, ku Tarka), voriconazole (Vfend), ndi warfarin (Coumadin, Jantoven). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi efavirenz, kapena atha kuonjezera chiopsezo kuti mungakhale ndi kugunda kwamtima kosazolowereka, onetsetsani kuti mwauza adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• auzeni adotolo ngati mwakhala mukukhala ndi nthawi yayitali ya QT (vuto losowa la mtima lomwe lingayambitse kukomoka kapena kugunda kwamtima mosasinthasintha), kugunda kwamtima kosazolowereka, mavuto ena amtima, adamwa mowa wambiri, kugwiritsa ntchito mankhwala osokoneza bongo, kapena kumwa kwambiri mankhwala akuchipatala. Muuzeni dokotala ngati mwakhalapo ndi vuto la matenda amisala kapena matenda amisala, khunyu, matenda a chiwindi (matenda opatsirana a chiwindi) kapena matenda aliwonse a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Simuyenera kutenga pakati mukamalandira chithandizo komanso kwa milungu 12 mutatha kumwa. Ngati mutha kukhala ndi pakati, muyenera kukhala ndi mayeso olakwika musanatenge mankhwalawa ndikugwiritsa ntchito njira yolerera panthawi yachipatala. Efavirenz ichepetsa kuchepa kwa mphamvu ya njira zolerera za mahomoni (mapiritsi oletsa kubala, zigamba, mphete, zopangira, kapena jakisoni), chifukwa chake simuyenera kugwiritsa ntchito njira yokhayo yolerera panthawi yachithandizo. Muyenera kugwiritsa ntchito njira yolepheretsa kulera (chipangizo chomwe chimatseketsa umuna kuti usalowe muchiberekero monga kondomu kapena diaphragm) limodzi ndi njira ina iliyonse yolerera yomwe mwasankha. Funsani dokotala wanu kuti akuthandizeni kusankha njira yolerera yomwe ingakuthandizeni. Mukakhala ndi pakati mukatenga efavirenz, itanani dokotala wanu.
• simuyenera kuyamwitsa ngati muli ndi kachilombo ka HIV kapena mukumwa efavirenz.
• Muyenera kudziwa kuti efavirenz imatha kukupangitsani kuti mukhale osinza, ozunguzika, kapena osatha kusinkhasinkha. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• Funsani adotolo za zakumwa zoledzeretsa pamene mukumwa efavirenz. Mowa umatha kukulitsa mavuto obwera chifukwa cha efavirenz.
• muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu kapena amayambitsa zina. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa kapena mikhalidwe. Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka mukamamwa mankhwala a efavirenz, onetsetsani kuti mwauza dokotala wanu.
• muyenera kudziwa kuti mafuta anu athupi amatha kuchuluka kapena kusunthira mbali zosiyanasiyana za thupi lanu monga mabere ndi msana, khosi ('' njati hump ''), komanso mozungulira m'mimba mwanu. Mutha kuwona kutaya mafuta m'thupi, kumaso, miyendo, ndi mikono.
• muyenera kudziwa kuti efavirenz imatha kusintha malingaliro anu, machitidwe anu, kapena thanzi lanu. Itanani dokotala wanu nthawi yomweyo mukakhala ndi zizindikiro izi mukamamwa efavirenz: kukhumudwa, kuganiza zodzipha kapena kukonzekera kapena kuyesa kutero, kukwiya kapena kuchita ndewu, kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe), kutaya kulumikizana ndi zenizeni, kapena malingaliro ena achilendo. Onetsetsani kuti banja lanu likudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati simungathe kupeza chithandizo chanokha.
• Muyenera kudziwa kuti efavirenz imatha kubweretsa mavuto amanjenje, kuphatikizapo encephalopathy (matenda owopsa omwe amatha kupha ubongo) miyezi kapena zaka mutangotenga efavirenz. Ngakhale mavuto amanjenje amatha kuyamba mutamwa efavirenz kwakanthawi, ndikofunikira kuti inu ndi dokotala muzindikire kuti akhoza kuyambitsidwa ndi efavirenz. Itanani dokotala wanu nthawi yomweyo ngati mukukumana ndi mavuto moyenera kapena molumikizana, kusokonezeka, mavuto akumbukiro, ndi zovuta zina zomwe zimayambitsidwa ndi ubongo, nthawi iliyonse mukamamwa mankhwala a efavirenz. Dokotala wanu angakuuzeni kuti musiye kumwa efavirenz.

Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Efavirenz ikhoza kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kupweteka m'mimba
• kutsegula m'mimba
• kudzimbidwa
• mutu
• chisokonezo
• kuyiwala
• kumva kuda nkhawa, kuchita mantha, kapena kukhumudwa
• chisangalalo chachilendo
• kuvuta kugona kapena kugona
• maloto achilendo
• kupweteka

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zatchulidwa mgulu la ZOCHITIKA, itanani dokotala wanu mwachangu:

• malungo
• zidzolo
• kuyabwa
• khungu, kuphulika, kapena khungu
• zilonda mkamwa
• diso la pinki
• kutupa kwa nkhope yako
• kukomoka
• kugunda kwamtima kosasintha
• kutopa kwambiri
• kusowa mphamvu
• kusowa chilakolako
• kupweteka kumtunda chakumanja kwam'mimba
• kutuluka mwachilendo kapena kuphwanya
• chikasu cha khungu kapena maso
• zizindikiro ngati chimfine
• kugwidwa

Efavirenz ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana.Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• mayendedwe amthupi lanu omwe simungathe kuwongolera
• chizungulire
• mutu
• zovuta kulingalira
• manjenje
• chisokonezo
• kuyiwala
• kuvuta kugona kapena kugona
• maloto achilendo
• Kusinza
• kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
• chisangalalo chachilendo
• malingaliro achilendo

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti awone kuyankha kwa thupi lanu ku efavirenz.

Musanayezetsedwe labotale, uzani adotolo ndi ogwira nawo ntchito kuti mukumwa efavirenz.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Sustiva^®

• Atripla^® (yokhala ndi Efavirenz, Emtricitabine, Tenofovir)