Glyburide ndi Metformin

Zamkati

• Musanatenge glyburide ndi metformin,
• Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.
• Glyburide ndi metformin zimatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo zizindikiro za hypoglycemia komanso izi:

Metformin nthawi zambiri imayambitsa matenda oopsa, otchedwa lactic acidosis. Uzani dokotala wanu ngati muli ndi matenda a impso. Dokotala wanu angakuuzeni kuti musatenge glyburide ndi metformin. Komanso, uzani dokotala ngati muli ndi zaka zopitilira 65 ndipo ngati mudadwalapo mtima; sitiroko; ketoacidosis ya shuga (shuga wamagazi wokwanira kwambiri kuti athe kuyambitsa zizindikilo zowopsa ndipo amafunikira chithandizo chadzidzidzi); chikomokere; kapena matenda a mtima kapena chiwindi. Uzani dokotala wanu ngati mukumwa acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, ku Qsymia), kapena zonisamide (Zonegran).

Uzani dokotala wanu ngati mwakhalapo ndi izi, kapena ngati mukukula mukalandira chithandizo: matenda akulu; kutsegula m'mimba kwambiri, kusanza, kapena kutentha thupi; kapena ngati mumamwa madzi ocheperako kuposa masiku onse pazifukwa zilizonse. Muyenera kusiya kumwa glyburide ndi metformin mpaka mutachira.

Ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, kapena njira iliyonse yayikulu yazachipatala, uzani adotolo kuti mukumwa glyburide ndi metformin. Komanso, auzeni dokotala ngati mukufuna kukhala ndi njira iliyonse ya x-ray yomwe amadyetsera utoto, makamaka ngati mumamwa kapena mumamwa mowa wambiri kapena mwakhala mukudwala matenda a chiwindi kapena mtima. Mungafunike kusiya kumwa glyburide ndi metformin musanachitike ndikuyembekezera maola 48 kuti muyambirenso kumwa mankhwala. Dokotala wanu angakuuzeni nthawi yoyenera kusiya kumwa glyburide ndi metformin komanso nthawi yomwe muyenera kuyambiranso.

Ngati mukumane ndi izi, siyani kumwa glyburide ndi metformin ndipo itanani dokotala nthawi yomweyo: kutopa kwambiri, kufooka, kapena kusapeza bwino; nseru; kusanza; kupweteka m'mimba; kuchepa kwa njala; kupuma mwamphamvu komanso mwachangu kapena kupuma movutikira; chizungulire; mutu wopepuka; kuthamanga kapena kuchepa kwa mtima; khungu lakuthwa; kupweteka kwa minofu; kapena kumva kuzizira m'manja kapena m'miyendo.

Uzani dokotala wanu ngati mumamwa mowa nthawi zonse kapena nthawi zina mumamwa mowa wambiri nthawi yochepa (kumwa mowa mwauchidakwa). Kumwa mowa kumawonjezera chiopsezo chokhala ndi lactic acidosis kapena kungayambitse shuga. Kumwa mowa mukamamwa glyburide ndi metformin nthawi zambiri kumatha kuyambitsa zizindikilo monga kutsuka (kufiira nkhope), kupweteka mutu, nseru, kusanza, kupweteka pachifuwa, kufooka, kusawona bwino, kusokonezeka m'maganizo, thukuta, kutsamwa, kupuma movutikira, ndi nkhawa. Funsani dokotala wanu zakumwa zoledzeretsa zomwe muyenera kumwa mukamamwa glyburide ndi metformin.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena asanalandire chithandizo komanso mukamalandira chithandizo kuti muwone momwe impso zanu zikugwirira ntchito komanso momwe thupi lanu limayankhira glyburide ndi metformin. Lankhulani ndi dokotala wanu za kuopsa kwakumwa glyburide ndi metformin.

Kuphatikizika kwa glyburide ndi metformin kumagwiritsidwa ntchito pochiza matenda amtundu wa 2 (momwe thupi siligwiritsa ntchito insulini mwachizolowezi motero silingathe kuwongolera kuchuluka kwa shuga m'magazi) mwa anthu omwe matenda awo ashuga sangathe kuwongoleredwa ndi zakudya komanso masewera olimbitsa thupi okha. Glyburide ndi gulu la mankhwala otchedwa sulfonylureas, ndipo metformin ali mgulu la mankhwala otchedwa biguanides. Glyburide imachepetsa shuga wamagazi popangitsa kuti kapamba apange insulin (chinthu chachilengedwe chomwe chimafunikira kuwononga shuga m'thupi) ndikuthandizira thupi kugwiritsa ntchito insulini moyenera. Mankhwalawa amangothandiza kuchepetsa shuga m'magazi mwa anthu omwe matupi awo amapanga insulin mwachilengedwe. Metformin imathandiza thupi lanu kuwongolera kuchuluka kwa shuga (shuga) m'magazi anu. Amachepetsa kuchuluka kwa shuga komwe mumamwa kuchokera pachakudya chanu komanso kuchuluka kwa shuga wopangidwa ndi chiwindi chanu. Zimathandizanso kuti thupi lanu lizigwiritsa ntchito insulini yake moyenera. Glyburide ndi metformin sagwiritsidwa ntchito pochiza matenda ashuga amtundu wa 1 (momwe thupi silimatulutsa insulin motero silingathe kuwongolera kuchuluka kwa shuga m'magazi) kapena matenda ashuga ketoacidosis (vuto lalikulu lomwe lingachitike ngati shuga wambiri asakuchiritsidwa ).

Kuphatikizana kwa Glyburide ndi metformin kumabwera ngati piritsi kuti mutenge pakamwa. Nthawi zambiri amatengedwa kamodzi kapena kawiri tsiku lililonse ndikudya. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani glyburide ndi metformin ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu mwina angakuyambitseni pa mlingo wochepa wa glyburide ndi metformin ndipo pang'onopang'ono akhoza kukulitsa mlingo wanu, osapitilira kamodzi pamasabata awiri aliwonse. kutengera yankho lanu. Onetsetsani magazi anu a magazi mosamala.

Glyburide ndi metformin kuphatikiza amawongolera matenda ashuga koma samachiritsa. Pitirizani kumwa glyburide ndi metformin ngakhale mukumva bwino. Osasiya kumwa glyburide ndi metformin osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa nthawi zina amapatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge glyburide ndi metformin,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la glyburide, metformin, chilichonse mwazomwe zimaphatikizidwa ndi glyburide ndi mapiritsi a metformin, kapena mankhwala ena aliwonse. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu ngati mukumwa bosentan (Tracleer). Dokotala wanu angakuuzeni kuti musamamwe glyburide ngati mukumwa mankhwalawa.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: amiloride (Midamor); ma angiotensin otembenuza enzyme (ACE) zoletsa monga benazepril (Lotensin, ku Lotrel), captopril, enalapril (Vasotec, mu Vaseretic), fosinopril, lisinopril (mu Zestoretic), moexipril (Univasc), perindopril (Aceon) , ramipril (Altace), ndi trandolapril (Mavik); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); aspirin kapena mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) kapena naproxen (Aleve, Naprosyn); beta-blockers monga atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard, ku Corzide), ndi propranolol (Hemangeol, Inderal, InnoPran); calcium blockers monga amlodipine (Norvasc), diltiazem (Cardizem, Cartia, Diltzac, ena), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), kapena verapamil (Calan, Covera, Verelan, in Zolemba); mankhwala enaake; cimetidine (Tagamet); clarithromycin (Biaxin, mu Prevpac); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); disopyramide (Norpace); okodzetsa ('mapiritsi amadzi'); fluconazole (Diflucan); fluoxetine (Prozac, Sarafem, Selfemra); furosemide (Lasix); mankhwala othandizira mahomoni; insulin kapena mankhwala ena a shuga; isoniazid (Laniazid, ku Rifamate, ku Rifater); MaO inhibitors monga isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ndi tranylcypromine (Parnate); mankhwala a chifuwa, mphumu, ndi chimfine; mankhwala a matenda amisala ndi nseru; miconazole (Lotrimin, Monistat, ena); morphine (MS Contin, ena); kachilombo; njira zakulera zam'kamwa (mapiritsi olera); oral steroids monga dexamethasone, methylprednisolone (Medrol), ndi prednisone (Rayos); phenytoin (Dilantin, Phenytek); probenecid (Benemid, ku Colbenemid); kupeza; quinidine (mu Nuedexta); quinine; mankhwala a quinolone ndi fluoroquinolone monga cinoxacin (sakupezekanso ku US, Cinobac), ciprofloxacin (Cipro), enoxacin (sikupezeka ku US, Penetrex), gatifloxacin, levofloxacin (Levaquin), lomefloxacin (sikupezeka ku US , Maxaquin), moxifloxacin (Avelox), nalidixic acid (sakupezekanso ku US, NegGram), norfloxacin (sikupezeka ku US, Noroxin), ofloxacin (sikupezeka ku US, Floxin), sparfloxacin likupezeka ku US, Zagam), trovafloxacin ndi alatrofloxacin kuphatikiza (sikupezeka ku US, Trovan); ranitidine (Zantac); mfuti; kupweteka kwa salicylate kumachepetsa monga choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal, magnesium salicylate (Doan's, ena), kapena salsalate (Argesic, Disalcid, Salgesic); sulfa maantibayotiki monga cotrimoxazole (Bactrim, Septra); sulfasalazine (Azulfidine); mankhwala a chithokomiro; triamterene (Dyrenium, ku Maxzide, ena); trimethoprim (Primsol, ku Bactrim, mu Septra); kapena vancomycin (Vancocin, ena).
• Kuphatikiza pa zomwe zalembedwa mu gawo LOFUNIKITSA CHENJEZO, uzani adotolo ngati inu kapena abale anu muli ndi vuto la G6PD (cholowa chobadwa chomwe chimawononga msanga maselo ofiira kapena kuchepa kwa magazi m'thupi); muuzeni dokotala ngati mwakhalapo kapena mudakhalapo ndi vuto la mahomoni okhudzana ndi adrenal, pituitary, kapena chithokomiro; kapena pachimake kapena matenda kagayidwe kachakudya acidosis.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga glyburide ndi metformin, itanani dokotala wanu.
• konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Glyburide ndi metformin zitha kupangitsa khungu lanu kukhala lowala ndi dzuwa.
• uzani dokotala ngati mumadya pang'ono kapena kuchita masewera olimbitsa thupi kuposa masiku onse. Izi zingakhudze shuga wanu wamagazi. Dokotala wanu adzakupatsani malangizo ngati izi zichitika.

Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Ndikofunika kudya chakudya chopatsa thanzi.

Musanayambe kumwa glyburide ndi metformin, funsani dokotala zomwe muyenera kuchita mukaiwala kumwa mankhwala kapena mwangozi mutenge owonjezera. Lembani malangizo awa kuti muthe kuwawunikiranso mtsogolo.

Monga mwalamulo, tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.

Glyburide ndi metformin zimatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kupweteka m'mimba
• nseru kapena kusanza
• kutsegula m'mimba
• chizungulire

Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu nthawi yomweyo:

• kupweteka pachifuwa
• zidzolo
• chikasu cha khungu kapena maso
• mipando yoyera
• mkodzo wakuda
• kupweteka kumtunda chakumanja kwam'mimba
• kutuluka mwachilendo kapena kuphwanya
• malungo
• chikhure
• kutupa kwa maso, nkhope, milomo, lilime, kapena mmero

Kafukufuku wina, anthu omwe adamwa mankhwala ofanana ndi glyburide kuti athe kuchiza matenda awo ashuga amatha kufa ndi mavuto amtima kuposa omwe amathandizidwa ndi insulin komanso kusintha kwa zakudya.

Glyburide ndi metformin zimatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri, ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo zizindikiro za hypoglycemia komanso izi:

• kugwidwa
• kutaya chidziwitso
• kutopa kwambiri
• kufooka
• kusapeza bwino
• kusanza
• nseru
• kupweteka m'mimba
• kuchepa kudya
• kupuma mwakathithi, mwachangu
• kupuma movutikira
• chizungulire
• wamisala
• kuthamanga kwa mtima mosafulumira kapena pang'onopang'ono
• khungu lakuthwa
• kupweteka kwa minofu
• kumva kuzizira

Dokotala wanu adzakuuzani momwe mungayang'anire mayankho anu ku glyburide ndi metformin poyeza kuchuluka kwa shuga wamagazi kunyumba. Tsatirani malangizowa mosamala.

Muyenera kuvala chibangili chizindikiritso cha ashuga kuti mutsimikizire kuti mumalandira chithandizo chadzidzidzi pakagwa mwadzidzidzi.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Kuzindikira^® (yokhala ndi Glyburide, Metformin)