Alireza (@ alireza_bb7)

Zamkati

• Ajovy ndi chiyani?
• Mtundu watsopano wa mankhwala
• Kuchita bwino
• Ajovy generic
• Ajovy amagwiritsa
• Ajovy wa mutu waching'alang'ala
• Kuchita bwino kwa mutu wa migraine
• Zotsatira zoyipa za Ajovy
• Zotsatira zofala kwambiri
• Zotsatira zoyipa
• Matupi awo sagwirizana
• Zotsatira zoyipa zazitali
• Njira zina ku Ajovy
• Otsutsa a CGRP
• Ajovy vs. mankhwala ena
• Ajovy vs. Aimovig
• Ajovy vs. Emgality
• Ajovy vs. Botox
• Mtengo wa Ajovy
• Thandizo lazachuma
• Mlingo wa Ajovy
• Mitundu ya mankhwala ndi mphamvu
• Mlingo wopewa mutu waching'alang'ala
• Ndingatani ngati ndaphonya mlingo?
• Kodi ndiyenera kugwiritsa ntchito mankhwalawa kwa nthawi yayitali?
• Momwe mungatenge Ajovy
• Momwe mungapangire jakisoni
• Kusunga nthawi
• Kutenga Ajovy ndi chakudya
• Momwe Ajovy amagwirira ntchito
• Zimatenga nthawi yayitali bwanji kuti zigwire ntchito?
• Ajovy ndi mowa
• Kuyanjana kwa Ajovy
• Ajovy ndi mimba
• Ajovy ndi kuyamwitsa
• Mafunso wamba za Ajovy
• Kodi Ajovy atha kugwiritsidwa ntchito pochiza mutu waching'alang'ala?
• Kodi Ajovy amasiyana bwanji ndi mankhwala ena a migraine?
• Kodi Ajovy amachiritsa mutu waching'alang'ala?
• Ndikatenga Ajovy, kodi nditha kusiya kumwa mankhwala anga ena?
• Ajovy bongo
• Zizindikiro zambiri za bongo
• Zomwe muyenera kuchita mukamagwiritsa ntchito bongo
• Machenjezo a Ajovy
• Kutha kwa Ajovy

Ajovy ndi chiyani?

Ajovy ndi dzina lachidziwitso la mankhwala omwe amagwiritsidwa ntchito popewera mutu wa mutu wa migraine mwa akulu. Zimabwera ngati syringe yoyambira kale. Mutha kudzichitira nokha Ajovy, kapena kulandira jakisoni wa Ajovy kuchokera kwa othandizira azaumoyo kuofesi ya dokotala wanu. Ajovy amatha kubayidwa mwezi uliwonse kapena kotala (kamodzi pa miyezi itatu iliyonse).

Ajovy muli mankhwala a fremanezumab, omwe ndi antioclonal antibody. Wotsutsana ndi monoclonal ndi mtundu wa mankhwala omwe amapangidwa kuchokera kuma cell a immune. Zimagwira ntchito poletsa mapuloteni ena amthupi lanu kuti asamagwire ntchito. Ajovy atha kugwiritsidwa ntchito popewa kupwetekedwa komanso kupwetekedwa mutu kwa mutu waching'alang'ala.

Mtundu watsopano wa mankhwala

Ajovy ndi gawo la mankhwala osokoneza bongo omwe amadziwika kuti calcitonin gene-peptide (CGRP) antagonists. Mankhwalawa ndiye mankhwala oyamba kupangidwa kuti ateteze mutu waching'alang'ala.

Food and Drug Administration (FDA) idavomereza Ajovy mu Seputembara 2018. Ajovy anali mankhwala achiwiri mgulu la otsutsana ndi CGRP omwe a FDA adavomereza kuti athandizire kupewa mutu waching'alang'ala.

Palinso otsutsana ena awiri a CGRP omwe alipo. Mankhwalawa amatchedwa Emgality (galcanezumab) ndi Aimovig (erenumab). Pali wotsutsa wachinayi wa CGRP wotchedwa eptinezumab yemwenso akuphunzira. Zikuyembekezeka kuvomerezedwa ndi FDA mtsogolomo.

Kuchita bwino

Kuti mudziwe zamphamvu za Ajovy, onani gawo la "Ajovy uses" pansipa.

Ajovy generic

Ajovy imangopezeka ngati mankhwala odziwika ndi dzina. Sikupezeka pakadali pano mu mawonekedwe achibadwa.

Ajovy imakhala ndi mankhwala a fremanezumab, omwe amatchedwanso fremanezumab-vfrm. Chifukwa "-vfrm" chikuwonekera kumapeto kwa dzinalo ndikuwonetsa kuti mankhwalawa ndi osiyana ndi mankhwala omwewo omwe angapangidwe mtsogolo. Ma antibodies ena monoclonal amatchulidwanso chimodzimodzi.

Ajovy amagwiritsa

US Food and Drug Administration (FDA) imavomereza mankhwala akuchipatala monga Ajovy kuti athetse kapena kupewa zovuta zina.

Ajovy wa mutu waching'alang'ala

A FDA avomereza Ajovy kuthandiza kupewa mutu wa migraine mwa akulu. Izi zimandipweteka kwambiri. Amakhalanso chizindikiro chachikulu cha mutu waching'alang'ala, womwe ndi matenda amitsempha. Kuzindikira kuwala ndi mawu, kunyansidwa, kusanza, ndi kuyankhula molakwika ndi zizindikilo zina zomwe zimatha kuchitika ndi mutu wa migraine.

Ajovy adavomerezedwa kuti ateteze mutu waching'onoting'ono wa migraine komanso episodic migraine. International Headache Society inanena kuti anthu omwe ali ndi ma episodic migraine amamva zowawa zosakwana 15 migraine kapena masiku opweteka mwezi uliwonse. Anthu omwe ali ndi mutu wopweteka kwambiri wa migraine, kumbali inayo, amakumana ndi masiku 15 kapena kupitilira apo mwezi uliwonse kwa miyezi itatu. Ndipo osachepera 8 a masiku awa ndi masiku a migraine.

Kuchita bwino kwa mutu wa migraine

Ajovy wapezeka kuti ndiwothandiza popewa mutu waching'alang'ala. Kuti mumve zambiri za momwe Ajovy adagwirira ntchito m'maphunziro azachipatala, onani zamankhwalawa.

American Headache Society ilimbikitsa kugwiritsa ntchito Ajovy popewa mutu waching'alang'ala mwa akulu omwe sangathe kuchepetsa kuchuluka kwa masiku ake a migraine ndimankhwala ena. Imalimbikitsanso Ajovy kwa anthu omwe sangathe kumwa mankhwala ena opewera migraine chifukwa chazovuta kapena kugwiritsa ntchito mankhwala osokoneza bongo.

Zotsatira zoyipa za Ajovy

Ajovy amatha kuyambitsa zovuta kapena zoyipa. Mndandanda wotsatirawu muli zina mwazovuta zomwe zingachitike mukamatenga Ajovy. Mndandandawu mulibe zovuta zonse zomwe zingachitike.

Kuti mumve zambiri pazomwe zingachitike chifukwa cha Ajovy, kapena maupangiri amomwe mungachitire ndi zovuta zina, lankhulani ndi dokotala kapena wamankhwala.

Zotsatira zofala kwambiri

Zotsatira zofala kwambiri za Ajovy ndikutengera malo obayira jekeseni. Izi zitha kuphatikizira zotsatirazi patsamba lomwe mumayamwa mankhwalawo:

• kufiira
• kuyabwa
• ululu
• chifundo

Zochita patsamba la jakisoni nthawi zambiri sizikhala zazikulu kapena zosakhalitsa. Zambiri mwa zotsatirazi zimatha kutha masiku angapo kapena milungu ingapo. Lankhulani ndi dokotala kapena wamankhwala ngati mavuto anu akukula kwambiri kapena samatha.

Zotsatira zoyipa

Sizachilendo kukhala ndi zovuta zoyipa kuchokera ku Ajovy, koma ndizotheka. Zotsatira zoyipa zazikulu za Ajovy ndizowopsa zomwe zimachitika chifukwa cha mankhwalawa. Onani pansipa kuti mumve zambiri.

Matupi awo sagwirizana

Monga momwe zimakhalira ndi mankhwala ambiri, anthu ena amatha kusokonezeka atatenga Ajovy. Zizindikiro za kuchepa pang'ono zimatha kuphatikiza:

• kuyabwa
• zotupa pakhungu
• Kutentha (kutentha ndi kufiira pakhungu lanu)

Zowonongeka kwambiri pa Ajovy ndizochepa. Zizindikiro zowopsa zakuphatikizika ndi izi:

• kutupa lilime, pakamwa, kapena pakhosi
• angioedema (kutupa pansi pa khungu lanu, makamaka m'maziso anu, milomo, manja, kapena mapazi)
• kuvuta kupuma

Ngati simukugwirizana ndi Ajovy, pitani kuchipatala nthawi yomweyo. Ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukukumana ndi vuto lachipatala, itanani 911.

Zotsatira zoyipa zazitali

Ajovy ndi mankhwala omwe avomerezedwa posachedwa mgulu latsopano la mankhwala. Zotsatira zake, pali kafukufuku wochepa kwambiri wazanthawi yayitali pankhani yachitetezo cha Ajovy, ndipo samadziwika pang'ono pazotsatira zake zazitali. Phunziro lalitali kwambiri lazachipatala (PS30) la Ajovy lidatenga chaka chimodzi, ndipo anthu omwe adafufuza sanafotokoze zovuta zilizonse.

Kuyankha tsamba la jakisoni ndiye zotsatira zofala kwambiri zomwe zafotokozedwera chaka chonse. Anthu anafotokoza zotsatirazi m'dera lomwe jakisoni anapatsidwa:

• ululu
• kufiira
• magazi
• kuyabwa
• khungu lopunduka kapena lokwezeka

Njira zina ku Ajovy

Palinso mankhwala ena omwe angathandize kupewa mutu waching'alang'ala. Zina zitha kukuyenererani kuposa ena. Ngati mukufuna kupeza njira ina m'malo mwa Ajovy, lankhulani ndi dokotala wanu. Amatha kukuthandizani kuti muphunzire zamankhwala ena omwe angakhale oyenera kwa inu.

Nazi zitsanzo za mankhwala ena omwe a FDA avomereza kuti athandize kupewa mutu waching'alang'ala:

• beta-blocker propranolol (Inderal, Inderal LA)
• mankhwala a neurotoxin onabotulinumtoxinA (Botox)
• mankhwala ena olanda, monga divalproex sodium (Depakote) kapena topiramate (Topamax, Trokendi XR)
• Otsutsana ndi peptide ena okhudzana ndi majini a calcitonin (CGRP): erenumab-aooe (Aimovig) ndi galcanezumab-gnlm (Emgality)

Nazi zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito polemba za kupewa mutu wa migraine:

• mankhwala ena olanda, monga valproate sodium
• mankhwala opatsirana pogonana, monga amitriptyline kapena venlafaxine (Effexor XR)
• beta-blockers, monga metoprolol (Lopressor, Toprol XL) kapena atenolol (Tenormin)

Otsutsa a CGRP

Ajovy ndi mtundu watsopano wamankhwala wotchedwa calcitonin peptide wokhudzana ndi majini (CGRP). Mu 2018, a FDA adavomereza Ajovy kuti ateteze mutu waching'alang'ala, pamodzi ndi ena awiri omwe amatsutsana ndi CGRP: Emgality ndi Aimovig. Mankhwala achinayi (eptinezumab) akuyembekezeka kuvomerezedwa posachedwa.

Momwe amagwirira ntchito

Otsutsana atatu a CGRP omwe alipo pakadali pano amagwira ntchito m'njira zosiyanasiyana kuti athetse mutu wa migraine.

CGRP ndi puloteni m'thupi lanu. Amalumikizidwa ndi vasodilation (kukulira kwa mitsempha yam'magazi) ndi kutupa muubongo, zomwe zimatha kubweretsa mutu wa mutu wa migraine. Kuti izi zitheke muubongo, CGRP iyenera kumangiriza (kulumikizana) ndi omwe amalandila. Olandira ndi mamolekyulu pamakoma am'magazi anu am'magazi.

Ajovy ndi Emgality amagwira ntchito yolumikizira CGRP. Izi zimalepheretsa CGRP kuti igwirizane ndi omwe amalandila. Aimovig, komano, imagwira ntchito yolumikizira kwa omwe amalandira. Izi zimapangitsa CGRP kuti isawalumikize.

Poletsa CGRP kuti isagwirizane ndi cholandirira chake, mankhwala atatuwa amathandiza kupewa kupuma kwa magazi ndi kutupa. Zotsatira zake, amatha kuthandiza kupewa mutu waching'alang'ala.

Mbali ndi mbali

Tchati ichi chikufanizira zambiri za Aimovig, Ajovy, and Emgality. Mankhwalawa ndi omwe amatsutsana nawo atatu a CGRP omwe akuvomerezedwa pakadali pano kuti athandize kupewa mutu wa migraine. (Kuti mumve zambiri za momwe Ajovy amafananira ndi mankhwalawa, onani gawo la "Ajovy vs. mankhwala ena" pansipa.)

Mitengo imatha kusiyanasiyana kutengera komwe muli, mankhwala omwe amagwiritsidwa ntchito, inshuwaransi yanu, ndi mapulogalamu othandizira opanga.

Ajovy vs. mankhwala ena

Mutha kudabwa momwe Ajovy amafananira ndi mankhwala ena omwe amaperekedwa kuti agwiritse ntchito chimodzimodzi. M'munsimu pali kufananiza pakati pa Ajovy ndi mankhwala angapo.

Ajovy vs. Aimovig

Ajovy muli mankhwala a fremanezumab, omwe ndi antioclonal antibody. Aimovig ili ndi erenumab, yemwenso ndi antioclonal antibody. Ma antibodies a monoclonal ndi mankhwala omwe apangidwa kuchokera kuma cell a immune. Amaletsa ntchito ya mapuloteni ena m'thupi lanu.

Ajovy ndi Aimovig amagwira ntchito mosiyanasiyana. Komabe, onsewa amayimitsa ntchito ya protein yotchedwa calcitonin peptide yokhudzana ndi jini (CGRP). CGRP imayambitsa vasodilation (kukulira kwa mitsempha yamagazi) ndi kutupa muubongo. Zotsatirazi zitha kubweretsa mutu waching'alang'ala.

Poletsa CGRP, Ajovy ndi Aimovig amathandizira kupewa kupuma kwa magazi komanso kutupa. Izi zitha kuthandiza kupewa mutu wa migraine.

Ntchito

Ajovy ndi Aimovig onse ndi ovomerezeka ndi FDA kuti ateteze mutu waching'alang'ala mwa akulu.

Mafomu ndi makonzedwe

Mankhwala a Ajovy ndi Aimovig onse amabwera ngati mawonekedwe a jakisoni omwe amaperekedwa pansi pa khungu lanu (subcutaneous). Mutha kudzipiritsa nokha mankhwala kunyumba. Mankhwala onsewa amatha kudzilowetsa m'malo atatu: kutsogolo kwa ntchafu zanu, kumbuyo kwa mikono yanu yakumtunda, kapena mimba yanu.

Ajovy amabwera mu mawonekedwe a syringe yomwe imadzazidwa ndi muyeso umodzi. Ajovy amatha kuperekedwa ngati jakisoni mmodzi wa 225 mg kamodzi pamwezi. Monga njira ina, itha kuperekedwa ngati majakisoni atatu a 675 mg omwe amaperekedwa kamodzi pachaka (kamodzi pa miyezi itatu iliyonse).

Aimovig imabwera ngati mawonekedwe a autoinjector omwe amadzaza ndi mlingo umodzi. Nthawi zambiri amaperekedwa ngati jakisoni wa 70-mg kamodzi pamwezi. Koma mlingo wa 140-mg pamwezi ukhoza kukhala wabwino kwa anthu ena.

Zotsatira zoyipa ndi zoopsa

Ajovy ndi Aimovig amagwira ntchito mofananamo chifukwa chake amayambitsa zovuta zina. Zimayambitsanso zovuta zina.

Zotsatira zofala kwambiri

Mndandandandawu muli zitsanzo za zovuta zoyipa zomwe zimatha kuchitika ndi Ajovy, ndi Aimovig, kapena ndi mankhwala onse (akamwedwa payekhapayekha).

• Zitha kuchitika ndi Ajovy:
  • Palibe zovuta zodziwika bwino
• Zitha kuchitika ndi Aimovig:
  • kudzimbidwa
  • kukokana kwa minofu kapena kuphipha
  • matenda opatsirana apamwamba monga chimfine kapena matenda a sinus
  • zizindikiro ngati chimfine
  • kupweteka kwa msana
• Zitha kuchitika ndi Ajovy ndi Aimovig:
  • zochita za jakisoni monga kupweteka, kuyabwa, kapena kufiira

Zotsatira zoyipa

Zotsatira zoyipa zoyipa kwa Ajovy ndi Aimovig ndizowopsa. Kuchita kotero sikofala, koma ndizotheka. (Kuti mumve zambiri, onani "Allergic reaction" mu gawo la "Zotsatira za Ajovy" pamwambapa).

Chitetezo cha mthupi

M'mayesero azachipatala amankhwala onsewa, anthu ochepa anali ndi chitetezo chamthupi. Izi zidapangitsa kuti matupi awo apange ma antibodies motsutsana ndi Ajovy kapena Aimovig.

Ma antibodies ndi mapuloteni omwe amateteza zinthu zakunja mthupi lanu. Thupi lanu limatha kupanga ma antibodies pazinthu zilizonse zakunja. Izi zimaphatikizapo ma antibodies monoclonal. Ngati thupi lanu limapanga ma antibodies ku Ajovy kapena Aimovig, mankhwalawa sangakugwiritseni ntchito. Koma kumbukirani kuti chifukwa Ajovy ndi Aimovig adavomerezedwa mu 2018, kudakali molawirira kwambiri kuti mudziwe momwe izi zingakhalire zofala komanso momwe zingakhudzire momwe anthu adzagwiritsire ntchito mankhwalawa mtsogolo.

Kuchita bwino

Mankhwalawa sanafanane mwachindunji pakuyesa kwamankhwala. Komabe, kafukufuku wapeza kuti Ajovy ndi Aimovig akhala othandiza popewera mutu wama episodic komanso wopweteka wa migraine.

Kuphatikiza apo, malangizo azithandizo za migraine amalimbikitsa kuti mankhwala azisankho ngati njira yosankhira anthu ena. Izi zikuphatikizapo anthu omwe sanathe kuchepetsa masiku awo a migraine pamwezi ndi mankhwala ena. Amaphatikizaponso anthu omwe sangalolere mankhwala ena chifukwa cha zovuta zina kapena kugwiritsa ntchito mankhwala osokoneza bongo.

Mtengo

Mtengo wa Ajovy kapena Aimovig umasiyana malinga ndi dongosolo lanu la mankhwala. Poyerekeza mitengo yamankhwalawa, onani GoodRx.com. Mtengo weniweni womwe mungalipire imodzi mwa mankhwalawa umadalira dongosolo lanu la inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Ajovy vs. Emgality

Ajovy ili ndi fremanezumab, yomwe ndi antioclonal antibody. Mphamvu imakhala ndi galcanezumab, yemwenso ndi antioclonal antibody. A monoclonal antibody ndi mtundu wa mankhwala opangidwa kuchokera kuma cell a immune. Imaletsa ntchito ya mapuloteni ena m'thupi lanu.

Ajovy ndi Emgality zonse zimayimitsa ntchito ya peptide yokhudzana ndi jini ya calcitonin (CGRP). CGRP ndi puloteni m'thupi lanu. Zimayambitsa vasodilation (kufutukuka kwa mitsempha yamagazi) ndi kutupa muubongo, komwe kumatha kubweretsa mutu waching'alang'ala.

Poletsa CGRP kuti isagwire ntchito, Ajovy ndi Emgality zimathandiza kupewa kupuma kwa magazi ndi kutupa muubongo. Izi zitha kuthandiza kupewa mutu wa migraine.

Ntchito

Ajovy ndi Emgality onse ndi ovomerezeka ndi FDA kuti ateteze mutu waching'alang'ala mwa akulu.

Mafomu ndi makonzedwe

Ajovy amabwera mu mawonekedwe a syringe yomwe imadzazidwa ndi muyeso umodzi. Mphamvu ya umunthu imabwera ngati jakisoni kapena cholembera chimodzi.

Mankhwala onsewa amabayidwa pansi pa khungu lanu (subcutaneous). Mutha kudzichitira nokha Ajovy ndi Emgality kunyumba.

Ajovy atha kudzibaya jekeseni pogwiritsa ntchito imodzi mwamasanjidwe awiri osiyana. Itha kuperekedwa ngati jakisoni wa 225 mg kamodzi pamwezi, kapena jakisoni atatu (okwanira 675 mg) kamodzi pa miyezi itatu iliyonse. Dokotala wanu adzakusankhirani nthawi yoyenera.

Mphamvu imaperekedwa ngati jakisoni wa 120 mg kamodzi pamwezi. (Mlingo woyamba mwezi woyamba ndi jakisoni wawiri okwana 240 mg.)

Onse Ajovy ndi Emgality atha kubayidwa m'malo atatu: kutsogolo kwa ntchafu zanu, kumbuyo kwa mikono yanu yakumtunda, kapena mimba yanu. Kuphatikiza apo, Emgality itha kubayidwa m'matako mwanu.

Zotsatira zoyipa ndi zoopsa

Ajovy and Emgality ndi mankhwala ofanana kwambiri ndipo amayambitsa mavuto ofanana.

Zotsatira zofala kwambiri

Mndandandandawu muli zitsanzo za zovuta zoyipa zomwe zimatha kuchitika ndi Ajovy, ndi Emgality, kapena ndi mankhwala onse (akamwedwa payekhapayekha).

• Zitha kuchitika ndi Ajovy:
  • Palibe zovuta zodziwika bwino
• Zitha kuchitika ndi Emgality:
  • kupweteka kwa msana
  • matenda opatsirana
  • chikhure
  • nkusani matenda
• Zitha kuchitika ndi Ajovy komanso Emgality:
  • zochita za jakisoni monga kupweteka, kuyabwa, kapena kufiira

Zotsatira zoyipa

Zomwe zimachitika mwazovuta ndizo zoyipa zazikulu za Ajovy ndi Emgality. Si zachilendo kukhala ndi zotere, koma ndizotheka. (Kuti mumve zambiri, onani "Allergic reaction" mu gawo la "Zotsatira za Ajovy" pamwambapa).

Chitetezo cha mthupi

M'mayeso osiyana azachipatala a mankhwala a Ajovy and Emgality, anthu ochepa adakumana ndi vuto lodziteteza ku matenda. Izi zimathandizira kuti matupi awo apange ma antibodies motsutsana ndi mankhwalawa.

Ma antibodies ndi mapuloteni amthupi omwe amateteza zakunja mthupi lanu. Thupi lanu limatha kupanga ma antibodies pachinthu chilichonse chakunja. Izi zimaphatikizapo ma antibodies monoclonal monga Ajovy ndi Emgality.

Ngati thupi lanu limapanga ma antibodies ku Ajovy kapena Emgality, mankhwalawa sangakuthandizeninso.

Komabe, ndizosachedwa kwambiri kudziwa kuti izi zitha kukhala zofala bwanji chifukwa Ajovy ndi Emgality adavomerezedwa mu 2018. Ndizofulumira kwambiri kudziwa momwe zingakhudzire momwe anthu adzagwiritsire ntchito mankhwala awiriwa mtsogolo.

Kuchita bwino

Mankhwalawa sanafanane mwachindunji pakuyesa kwamankhwala. Komabe, kafukufuku wapeza kuti Ajovy ndi Emgality ndizothandiza popewa mutu wama episodic komanso wopweteka wa migraine.

Kuphatikiza apo, Ajovy ndi Emgality amalimbikitsidwa ndi malangizo azithandizo kwa anthu omwe sangathe kumwa mankhwala ena chifukwa cha zovuta zina kapena chifukwa chogwiritsa ntchito mankhwala osokoneza bongo. Amalimbikitsidwanso kwa anthu omwe sangakwanitse kuchepetsa kuchuluka kwa migraine pamwezi ndi mankhwala ena.

Mtengo

Mtengo wa Ajovy kapena Emgality umatha kusiyanasiyana kutengera dongosolo lanu lamankhwala. Poyerekeza mitengo yamankhwalawa, onani GoodRx.com. Mtengo weniweni womwe mungalipire imodzi mwa mankhwalawa umadalira dongosolo lanu la inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Ajovy vs. Botox

Ajovy ili ndi fremanezumab, yomwe ndi antioclonal antibody. A monoclonal antibody ndi mtundu wa mankhwala opangidwa kuchokera kuma cell a immune. Ajovy amathandiza kupewa mutu wa mutu waching'alang'ala pomaletsa ntchito ya mapuloteni ena omwe amayambitsa migraine.

Chowonjezera chachikulu cha mankhwala ku Botox ndi onabotulinumtoxinA. Mankhwalawa ndi gawo limodzi la mankhwala omwe amadziwika kuti ma neurotoxin. Botox imagwira ntchito polepheretsa kwakanthawi minofu yomwe idalowetsedwa. Izi zimakhudza minofu kuti zizindikire zopweteka zisasinthidwe. Zimaganiziridwa kuti izi zimathandiza kupewa mutu wa migraine asanayambe.

Ntchito

A FDA avomereza Ajovy popewa kupweteka kwa mutu kwa anthu akuluakulu.

Botox yavomerezedwa kuti ipewe matenda opweteka a migraine mwa akulu. Botox idavomerezedwanso kuti ichiritse zinthu zambiri, kuphatikiza:

• kufalikira kwa minofu
• chikhodzodzo chopitirira muyeso
• thukuta kwambiri
• khomo lachiberekero dystonia (khosi lopindika lopweteka)
• kupweteka kwa chikope

Mafomu ndi makonzedwe

Ajovy amabwera ngati syringe ya mlingo umodzi. Amapatsidwa ngati jakisoni pansi pa khungu lanu (subcutaneous) yomwe mutha kudzipatsa nokha kunyumba, kapena kukhala ndi othandizira azaumoyo omwe amakupatsani kuofesi ya dokotala wanu.

Ajovy atha kupatsidwa kamodzi kapena kawiri: jakisoni 225-mg kamodzi pamwezi, kapena jakisoni atatu (675 mg) kamodzi pamiyezi itatu iliyonse. Dokotala wanu adzakusankhirani nthawi yoyenera.

Ajovy itha kubayidwa m'malo atatu: kutsogolo kwa ntchafu zanu, kumbuyo kwa mikono yanu yakumtunda, kapena mimba yanu.

Botox imaperekedwanso ngati jakisoni, koma nthawi zonse imaperekedwa kuofesi ya dokotala. Imabayidwa mu mnofu (mnofu), nthawi zambiri pamasabata 12 aliwonse.

Malo omwe Botox amajambulidwa amaphatikizapo pamphumi panu, pamwamba ndi pafupi ndi makutu anu, pafupi ndi tsitsi lanu pamutu panu, komanso kumbuyo kwa khosi ndi mapewa anu. Paulendo uliwonse, dokotala wanu amakupatsani jakisoni 31 mderali.

Zotsatira zoyipa ndi zoopsa

Ajovy ndi Botox onse amagwiritsidwa ntchito popewa mutu waching'alang'ala, koma amagwira ntchito m'njira zosiyanasiyana mthupi. Chifukwa chake, ali ndi zovuta zina zofanana, ndipo zina zosiyana.

Zotsatira zofala kwambiri

Mndandandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Ajovy, ndi Botox, kapena ndi mankhwala onse (akamwedwa payekhapayekha).

• Zitha kuchitika ndi Ajovy:
  • zotsatira zochepa wamba wamba
• Zitha kuchitika ndi Botox:
  • zizindikiro ngati chimfine
  • kupweteka mutu kapena kupweteka mutu kwa mutu waching'alang'ala
  • chikope kugwa
  • ziwalo zaminyewa yamaso
  • kupweteka kwa khosi
  • kuuma minofu
  • kupweteka kwa minofu ndi kufooka
• Zitha kuchitika ndi Ajovy ndi Botox:
  • jakisoni malo zochita

Zotsatira zoyipa

Mndandandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Ajovy, ndi Xultophy, kapena ndi mankhwala onse (akamwedwa payekhapayekha).

• Zitha kuchitika ndi Ajovy:
  • zotsatira zoyipa zingapo zoyipa
• Zitha kuchitika ndi Botox:
  • kufalikira kwa ziwalo ku minofu yapafupi *
  • vuto kumeza komanso kupuma
  • matenda akulu
• Zitha kuchitika ndi Ajovy ndi Botox:
  • aakulu thupi lawo siligwirizana

* Botox ali ndi chenjezo lolembedwa kuchokera ku FDA lonena za kufalikira kwa ziwalo ku minofu yapafupi ikutsatira jakisoni. Chenjezo la nkhonya ndiye chenjezo lamphamvu kwambiri lomwe a FDA amafunikira. Imachenjeza madokotala ndi odwala za zovuta zamankhwala zomwe zitha kukhala zowopsa.

Kuchita bwino

Kupweteka kwa migraine nthawi zonse ndi vuto lokhalo lomwe Ajovy ndi Botox amagwiritsidwa ntchito popewa.

Maupangiri azithandizo amalimbikitsa Ajovy ngati njira yothetsera anthu omwe sangachepetse kuchuluka kwa mutu waching'alang'ala wokwanira ndi mankhwala ena. Ajovy amalimbikitsidwanso kwa anthu omwe sangathe kulekerera mankhwala ena chifukwa cha zovuta zawo kapena kulumikizana kwa mankhwala.

American Academy of Neurology imalimbikitsa Botox ngati njira yothandizira anthu omwe ali ndi mutu wopweteka wa migraine.

Maphunziro azachipatala sanafananitse mwachindunji mphamvu ya Ajovy ndi Botox. Koma kafukufuku wosiyana adawonetsa Ajovy ndi Botox kukhala othandiza popewa mutu wopweteka wa migraine.

Mtengo

Mtengo wa Ajovy kapena Botox umasiyana malinga ndi dongosolo lanu la mankhwala. Poyerekeza mitengo yamankhwalawa, onani GoodRx.com. Mtengo weniweni womwe mungalipire imodzi mwa mankhwalawa umadalira dongosolo lanu la inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Mtengo wa Ajovy

Monga mankhwala onse, mitengo ya Ajovy imatha kusiyanasiyana.

Mtengo wanu weniweni umadalira kukutetezani kwanu pa inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Thandizo lazachuma

Ngati mukufuna thandizo lazachuma kuti mulipire Ajovy, thandizo lilipo.

A Teva Pharmaceuticals, omwe amapanga Ajovy, ali ndi mwayi wosunga ndalama womwe ungakuthandizeni kuti muchepetse ndalama za Ajovy. Kuti mumve zambiri komanso kuti mudziwe ngati mukuyenera, pitani patsamba lino.

Mlingo wa Ajovy

Zotsatirazi zikufotokozera miyezo yanthawi zonse ya Ajovy. Komabe, onetsetsani kuti mwatenga mlingo womwe dokotala akukulemberani. Dokotala wanu adzakusankhirani dongosolo labwino kwambiri la dosing.

Mitundu ya mankhwala ndi mphamvu

Ajovy amabwera mu syringe imodzi yamtundu umodzi. Sirinji iliyonse imakhala ndi 225 mg ya fremanezumab mu 1.5 mL yankho.

Ajovy amaperekedwa ngati jakisoni pansi pa khungu lanu (subcutaneous). Mutha kudzipiritsa mankhwala kunyumba, kapena wothandizira zaumoyo akhoza kukupatsani jakisoni kuofesi yanu.

Mlingo wopewa mutu waching'alang'ala

Pali magawo awiri amiyeso yolimbikitsira:

• jakisoni mmodzi wa 225-mg subcutaneous woperekedwa mwezi uliwonse, kapena
• jakisoni atatu 225-mg subcutaneous operekedwa limodzi (mmodzimmodzi) kamodzi pa miyezi itatu iliyonse

Inu ndi dokotala wanu mudzapeza dongosolo labwino kwambiri la dosing kwa inu, kutengera zomwe mumakonda komanso moyo wanu.

Ndingatani ngati ndaphonya mlingo?

Mukaiwala kapena kuphonya mlingo, perekani mlingowo mukakumbukira.Pambuyo pake, pitilizani ndandanda yovomerezeka.

Mwachitsanzo, ngati muli pa ndandanda ya mwezi uliwonse, konzekerani mlingo wotsatirawo kwa milungu inayi mutadzipiritsa. Ngati mukukhala pamndandanda wa miyezi itatu iliyonse, perekani mlingo wotsatira masabata 12 mutadzipiritsa.

Kodi ndiyenera kugwiritsa ntchito mankhwalawa kwa nthawi yayitali?

Ngati inu ndi dokotala mukuwona kuti Ajovy ndiwotetezeka komanso wogwira ntchito kwa inu, mutha kugwiritsa ntchito mankhwalawa nthawi yayitali popewa mutu waching'alang'ala.

Momwe mungatenge Ajovy

Ajovy ndi jakisoni yemwe amaperekedwa pansi pa khungu (subcutaneous) kamodzi pamwezi kapena kamodzi miyezi itatu iliyonse. Mutha kudzipatsa jekeseni kunyumba, kapena kukhala ndi wothandizira zaumoyo amakupatsani jakisoni kuofesi ya dokotala wanu. Nthawi yoyamba mukalandira mankhwala a Ajovy, wothandizira zaumoyo wanu akhoza kufotokoza momwe mungadzibayire nokha mankhwalawo.

Ajovy amabwera ngati muyezo umodzi, 225-mg syringe yodzaza. Sirinji iliyonse imakhala ndi mlingo umodzi wokha ndipo imayenera kugwiritsidwa ntchito kamodzi kenako nkuitaya.

Pansipa pali zambiri zamomwe mungagwiritsire ntchito syringe woyikiratu. Kuti mumve zambiri, kanema, ndi zithunzi za malangizo a jakisoni, onani tsamba la wopanga.

Momwe mungapangire jakisoni

Dokotala wanu amakupatsirani 225 mg kamodzi pamwezi, kapena 675 mg kamodzi miyezi itatu (kotala). Ngati mwapatsidwa 225 mg pamwezi, mudzadzipatsa jekeseni imodzi. Ngati mwapatsidwa 675 mg kotala, mudzadzipatsa jakisoni atatu osiyana wina ndi mnzake.

Kukonzekera jekeseni

• Patatha mphindi makumi atatu musanabaye jakisoni wamankhwala, chotsani sirinjiyo m'firiji. Izi zimapangitsa kuti mankhwalawa azitha kutentha ndikutentha. Sungani kapu pa syringe mpaka mutakonzeka kugwiritsa ntchito syringe. (Ajovy akhoza kusungidwa kutentha mpaka maola 24. Ngati Ajovy amasungidwa kunja kwa firiji kwa maola 24 osagwiritsidwa ntchito, osayikanso mufiriji. Itayireni mu chidebe chanu chakuthwa.)
• Musayese kutentha syringe mwachangu poika ma microwave kapena kuyendetsa madzi otentha. Komanso, musagwedeze sirinji. Kuchita izi kumapangitsa kuti Ajovy asakhale otetezeka komanso ogwira ntchito.
• Mukamatulutsa sirinji m'phukusi mwake, onetsetsani kuti mumateteza ku kuwala.
• Mukamayembekezera kuti syringe izitenthetsa kutentha, pezani gauze kapena thonje, chopukutira mowa, ndi chidebe chanu chotayira. Onetsetsani kuti muli ndi masilinji oyenerera mulingo woyenera.
• Yang'anani pa syringe kuti muwonetsetse kuti mankhwalawo alibe mitambo kapena kutha ntchito. Madziwo ayenera kukhala omveka pang'ono achikaso. Palibe vuto ngati pali thovu. Koma ngati madziwo atuluka mtundu kapena mitambo, kapena ngati muli tizidutswa tating'ono tolimba, musagwiritse ntchito. Ndipo ngati pali ming'alu kapena zotuluka mu syringe, musazigwiritse ntchito. Ngati kuli kotheka, funsani dokotala wanu za kupeza chatsopano.
• Gwiritsani ntchito sopo ndi madzi kusamba m'manja, kenako sankhani malo obayira jekeseni wanu. Mutha kubaya pansi pa khungu lanu m'malo atatu awa:
• patsogolo pa ntchafu zanu (mainchesi awiri pamwamba pa bondo lanu kapena mainchesi awiri pansi pa kubuula kwanu)
• kumbuyo kwa mikono yanu yakumtunda
• mimba yanu (osachepera mainchesi awiri kuchokera kumimba kwanu)
• Ngati mukufuna kubaya mankhwalawo kumbuyo kwa mkono wanu, wina angafunike kuti akubayireni mankhwalawo.
• Gwiritsani ntchito chopukutira chakumwa choledzeretsa kuti muyeretse malo omwe mwasankha. Onetsetsani kuti mowa ndi wouma musanawapatse mankhwalawo.
• Ngati mukudzipatsa jakisoni atatu, musadzipatse jakisoni pamalo omwewo. Ndipo musalowe m'malo omwe ali ndi zovulala, zofiira, zipsera, zolembedwa mphini, kapena zovuta kuzikhudza.

Kubayira jekeseni wa Ajovy

1. Tengani kapu ya singano pa syringe ndikuiponya mu zinyalala.
2. Dulani pang'onopang'ono khungu limodzi la khungu lomwe mukufuna kulibaya.
3. Ikani singanoyo pakhungu latsinalo pamtunda wa madigiri 45 mpaka 90.
4. Singanoyo italowetsedwa kwathunthu, gwiritsani ntchito chala chanu chachikulu kuti mukankhire pang'onopang'ono plunger momwe angathere.
5. Pambuyo pobayira Ajovy, kokani singanoyo pakhungu ndikumasula khungu. Pofuna kuti musadziphatikize, musabwezeretse singano.
6. Lembani pang'onopang'ono mpira wa thonje kapena gauze pamalo opangira jekeseni kwa masekondi pang'ono. Osapukuta malowa.
7. Ponyani syringe ndi singano zomwe mumagwiritsa ntchito nthawi yomweyo.

Kusunga nthawi

Ajovy imayenera kutengedwa kamodzi mwezi uliwonse kapena kamodzi miyezi itatu (kotala), kutengera zomwe dokotala akukuuzani. Ikhoza kumwedwa nthawi iliyonse patsiku.

Ngati mwaphonya mlingo, tengani Ajovy mukamakumbukira. Mlingo wotsatira uyenera kukhala mwezi umodzi kapena miyezi itatu mutamutenga, kutengera dongosolo lanu la dosing. Chida chokumbutsirani mankhwala chingakuthandizeni kukumbukira kutenga Ajovy panthawi yake.

Kutenga Ajovy ndi chakudya

Ajovy atha kumwedwa kapena wopanda chakudya.

Momwe Ajovy amagwirira ntchito

Ajovy ndi anti-monoclonal antibody. Mtundu uwu wa mankhwala ndi mapuloteni apadera amthupi omwe amapangidwa mu labu. Ajovy amagwira ntchito poletsa ntchito ya protein yotchedwa calcitonin peptide yokhudzana ndi jini (CGRP). CGRP imakhudzidwa ndi vasodilation (kukulitsa mitsempha yamagazi) ndi kutupa muubongo wanu.

CGRP imakhulupirira kuti imathandiza kwambiri pakumayambitsa mutu wa migraine. M'malo mwake, anthu akamayamba kudwala mutu waching'alang'ala, amakhala ndi CGRP m'magazi awo ambiri. Ajovy amathandiza kuti mutu waching'alang'ala usayambike poyimitsa ntchito ya CGRP.

Mankhwala ambiri amayang'ana (kuchitapo kanthu) mankhwala ambiri kapena ziwalo zama cell mthupi lanu. Koma Ajovy ndi ma antibodies ena monoclonal amangolimbana ndi chinthu chimodzi mthupi. Zotsatira zake, pakhoza kukhala kulumikizana pang'ono kwa mankhwala ndi zovuta zina ndi Ajovy. Izi zitha kupangitsa chisankho chabwino kwa anthu omwe sangamwe mankhwala ena chifukwa cha zovuta zina kapena kulumikizana ndi mankhwala.

Ajovy amathanso kukhala chisankho chabwino kwa anthu omwe ayesa mankhwala ena, koma mankhwalawo sanachite zokwanira kuti achepetse masiku awo a migraine.

Zimatenga nthawi yayitali bwanji kuti zigwire ntchito?

Zitha kutenga milungu ingapo kusintha kwa migraine kulikonse komwe Ajovy amachititsa kuti aoneke. Ndipo zingatenge miyezi ingapo kuti Ajovy achite bwino.

Zotsatira zamaphunziro azachipatala zidawonetsa kuti anthu ambiri omwe adatenga Ajovy adakumana ndi masiku ochepa a migraine pasanathe mwezi umodzi atamwa mankhwala oyamba. Kwa miyezi ingapo, kuchuluka kwa masiku a migraine kunapitilira kuchepa kwa anthu omwe anali phunziroli.

Ajovy ndi mowa

Palibe kulumikizana pakati pa Ajovy ndi mowa.

Komabe, kwa anthu ena, kumwa mowa ndikumwa Ajovy kumawoneka kuti kumapangitsa mankhwalawa kukhala osagwira ntchito. Izi ndichifukwa choti mowa umayambitsa matenda a migraine kwa anthu ambiri, ndipo ngakhale mowa pang'ono ungayambitse mutu wa migraine kwa iwo.

Mukawona kuti mowa umayambitsa kupweteka kwambiri kapena kupweteka mutu kwa migraine, muyenera kupewa zakumwa zomwe zili ndi mowa.

Kuyanjana kwa Ajovy

Ajovy sanawonetsedwe kuti akuyanjana ndi mankhwala ena. Komabe, nkofunikirabe kukambirana ndi dokotala kapena wamankhwala zamankhwala zilizonse, mavitamini, zowonjezera, komanso mankhwala owonjezera omwe mumamwa musanayambe Ajovy.

Ajovy ndi mimba

Sizikudziwika ngati Ajovy ndiotetezeka kugwiritsa ntchito nthawi yapakati. Pamene Ajovy adapatsidwa kwa akazi apakati m'maphunziro a nyama, palibe chiopsezo chomwe chidawonetsedwa pamimba. Koma zotsatira za maphunziro a nyama sizimaneneratu nthawi zonse momwe mankhwala angakhudzire anthu.

Ngati muli ndi pakati kapena mukuganiza zokhala ndi pakati, lankhulani ndi dokotala wanu. Amatha kuthandizira kudziwa ngati Ajovy ndi chisankho chabwino kwa inu. Mungafunike kudikirira kuti mugwiritse ntchito Ajovy mpaka simudzakhalanso ndi pakati.

Ajovy ndi kuyamwitsa

Sizikudziwika ngati Ajovy amadutsa mkaka wa m'mawere wa anthu. Chifukwa chake, sizikudziwika ngati Ajovy ndiotetezeka kugwiritsa ntchito poyamwitsa.

Ngati mukuganiza zokhala ndi chithandizo cha Ajovy mukamayamwitsa, lankhulani ndi adokotala zaubwino ndi zoopsa zomwe zingachitike. Mukayamba kumwa Ajovy, mungafunikire kusiya kuyamwitsa.

Mafunso wamba za Ajovy

Nawa mayankho pamafunso omwe amafunsidwa zambiri za Ajovy.

Kodi Ajovy atha kugwiritsidwa ntchito pochiza mutu waching'alang'ala?

Ayi, Ajovy si chithandizo cha mutu waching'alang'ala. Ajovy amathandiza kupewa mutu waching'alang'ala asanayambe.

Kodi Ajovy amasiyana bwanji ndi mankhwala ena a migraine?

Ajovy amasiyana ndimankhwala ena ambiri a migraine chifukwa ndi imodzi mwamankhwala oyamba kupangidwa kuti athandize kupewa mutu waching'alang'ala. Ajovy ndi gawo la mankhwala atsopano otchedwa calcitonin peptide okhudzana ndi majini (CGRP) antagonists.

Mankhwala ambiri omwe amagwiritsidwa ntchito popewera mutu waching'alang'ala amapangidwira ntchito zosiyanasiyana, monga kuchiza khunyu, kukhumudwa, kapena kuthamanga kwa magazi. Ambiri mwa mankhwalawa amagwiritsidwa ntchito ngati malembo othandiza kupewa mutu waching'alang'ala.

Ajovy amasiyana ndi mankhwala ena ambiri a migraine chifukwa amabayidwa kamodzi pamwezi kapena kamodzi miyezi itatu iliyonse. Mankhwala ambiri omwe amagwiritsidwa ntchito popewera mutu waching'alang'ala amabwera ngati mapiritsi omwe muyenera kumwa kamodzi tsiku lililonse.

Mankhwala osakanikirana ndi Botox. Botox ndi jakisoni, koma mumalandira kamodzi pakatha miyezi itatu kuofesi ya dokotala wanu. Mutha kudzipiritsa nokha Ajovy kunyumba kapena kukhala ndi othandizira azaumoyo amakupatsani jakisoni kuofesi ya dokotala wanu.

Komanso, Ajovy ndi anti-monoclonal antibody, womwe ndi mtundu wa mankhwala opangidwa kuchokera kuma cell amthupi. Chiwindi sichimaphwanya mankhwalawa, monganso mankhwala ena ambiri omwe amagwiritsidwa ntchito popewa mutu waching'alang'ala. Izi zikutanthauza kuti Ajovy ndi ma anti-monoclonal antibodies ena amalumikizana pang'ono ndi mankhwala kuposa mankhwala ena omwe amathandiza kupewa mutu waching'alang'ala.

Kodi Ajovy amachiritsa mutu waching'alang'ala?

Ayi, Ajovy samathandiza kuchiza mutu waching'alang'ala. Pakadali pano palibe mankhwala omwe angachiritse mutu waching'alang'ala. Mankhwala a migraine omwe alipo angathandize kupewa kapena kuchiza mutu waching'alang'ala.

Ndikatenga Ajovy, kodi nditha kusiya kumwa mankhwala anga ena?

Izi zimadalira. Yankho la aliyense pa Ajovy ndi losiyana. Ngati mankhwalawa amachepetsa kuchuluka kwa mutu wanu wa migraine mpaka kuchuluka kwake, ndizotheka kuti mutha kusiya kugwiritsa ntchito mankhwala ena oteteza. Koma mukayamba kumwa Ajovy, dokotala wanu angakulembereni limodzi ndi mankhwala ena oteteza.

Kafukufuku wazachipatala adapeza kuti Ajovy ndiotetezeka komanso yothandiza kugwiritsidwa ntchito ndi mankhwala ena oteteza. Mankhwala ena omwe dokotala angakupatseni ndi Ajovy ndi topiramate (Topamax), propranolol (Inderal), ndi mankhwala ena opatsirana. Ajovy itha kugwiritsidwanso ntchito ndi onabotulinumtoxinA (Botox).

Mukayesa Ajovy kwa miyezi iwiri kapena itatu, dokotala wanu angakambirane nanu kuti awone momwe mankhwalawa amakuthandizirani. Pamenepo, nonse awiri mutha kusankha kuti musiye kumwa mankhwala ena otetezera, kapena kuti muchepetse kuchuluka kwa mankhwalawa.

Ajovy bongo

Kubaya jakisoni wambiri wa Ajovy kumatha kukulitsa chiopsezo chazomwe zimachitika patsamba lanu. Ngati simugwirizana ndi Ajovy, mutha kukhala pachiwopsezo chazovuta zina.

Zizindikiro zambiri za bongo

Zizindikiro za bongo zingaphatikizepo:

• kupweteka kwambiri, kuyabwa, kapena kufiira mdera lomwe lili pafupi ndi jakisoni
• kuchapa
• ming'oma
• angioedema (kutupa pansi pakhungu)
• kutupa kwa lilime, mmero, kapena pakamwa
• kuvuta kupuma

Zomwe muyenera kuchita mukamagwiritsa ntchito bongo

Ngati mukuganiza kuti mwamwa kwambiri mankhwalawa, itanani dokotala wanu kapena funsani malangizo kuchokera ku American Association of Poison Control Center ku 800-222-1222 kapena kudzera pa chida chawo pa intaneti. Koma ngati matenda anu akukulira, itanani 911 kapena pitani kuchipatala chapafupi pomwepo.

Machenjezo a Ajovy

Musanatenge Ajovy, lankhulani ndi dokotala wanu za mbiri yanu. Simuyenera kutenga Ajovy ngati muli ndi mbiri yokhudzidwa kwambiri ndi Ajovy kapena zina zake. Kuchepetsa chidwi cha hypersensitivity kungayambitse zizindikiro monga:

• zotupa pakhungu
• kuyabwa
• kuvuta kupuma
• angioedema (kutupa pansi pakhungu)
• kutupa kwa lilime, pakamwa, ndi pakhosi

Kutha kwa Ajovy

Ajovy akatulutsidwa ku pharmacy, wamankhwalayo adzawonjezera tsiku lotha ntchito pazolemba zomwe zili pachidebecho. Tsikuli limakhala chaka chimodzi kuchokera tsiku lomwe mankhwalawa adaperekedwa.

Cholinga cha masiku otha ntchitowa ndikutsimikizira kuti mankhwalawa ndi othandiza panthawiyi. Maganizo apano a Food and Drug Administration (FDA) ndikupewa kugwiritsa ntchito mankhwala omwe atha ntchito.

Kutalika kwa nthawi yayitali kumadalira mankhwala, kuphatikiza momwe mankhwalawo amasungidwira.

Masirinji a Ajovy ayenera kusungidwa mufiriji muchidebe choyambirira kuti muwateteze ku kuwala. Amatha kusungidwa bwino m'firiji kwa miyezi 24, kapena mpaka tsiku lomalizira lidzaikidwa pachidebecho. Mukatulutsidwa mufiriji, sirinji iliyonse imayenera kugwiritsidwa ntchito pasanathe maola 24.

Ngati mwagwiritsa ntchito mankhwala omwe sanadutse tsiku lomaliza, lankhulani ndi wamankhwala wanu ngati mungakwanitse kuugwiritsabe ntchito.

Chodzikanira:Nkhani Zamankhwala Masiku Ano yachita khama kwambiri kuti zitsimikizire kuti zidziwitso zonse ndizolondola, zomveka bwino, komanso zatsopano. Komabe, nkhaniyi sikuyenera kugwiritsidwa ntchito m'malo mwa chidziwitso ndi ukadaulo wa akatswiri pazachipatala. Muyenera kufunsa adotolo kapena akatswiri azaumoyo musanamwe mankhwala aliwonse. Zambiri zamankhwala zomwe zili pano zitha kusintha ndipo sizingapangidwe kuti zigwiritse ntchito, mayendedwe, zodzitetezera, machenjezo, kulumikizana ndi mankhwala, kusokonezeka, kapena zovuta zina. Kusapezeka kwa machenjezo kapena zidziwitso za mankhwala omwe apatsidwa sikuwonetsa kuti kuphatikiza mankhwala kapena mankhwalawa ndiwotetezeka, ogwira ntchito, komanso oyenera kwa odwala onse kapena ntchito zina zilizonse.