Osteopetrosis: ndi chiyani, zizindikiro ndi chithandizo

Zamkati

• Zizindikiro za Osteopetrosis
• Zifukwa za osteopetrosis
• Momwe mankhwalawa amachitikira

Osteopetrosis ndi matenda obadwa nawo osakanikirana ndi mafupa omwe mafupa amakhala owopsa kuposa momwe zimakhalira, zomwe zimachitika chifukwa cha kusalingana kwa maselo omwe amachititsa kuti mafupa apangike komanso kusweka, zomwe zimapangitsa kuti mafupa awonjezeke kwambiri ndipo izi zimawonekera monga mafupa olimba kwambiri, kumva movutikira ndikusintha pakukula kwa mitsempha, mwachitsanzo.

Chithandizo cha osteopetrosis chiyenera kulimbikitsidwa ndi gulu lachipatala lomwe limaphatikizapo dokotala wa ana, hematologist ndi orthopedist, ndipo kupatsirana mafupa a mafupa nthawi zambiri kumalimbikitsidwa kuti zithandizire kugwira ntchito kwa maselo okhudzana ndi mafupa.

Zizindikiro za Osteopetrosis

Zizindikiro za osteopetrosis zimatha kudziwika atangobadwa, chifukwa ndi matenda obadwa nawo, kapena pakhoza kukhala zizindikilo zokha atakula. Chikhalidwe chachikulu cha osteopetrosis ndikukula kwa kuchuluka kwa mafupa, komwe kumatha kuwonedwa pofufuza densitometry ya mafupa.

Kuphatikiza apo, palinso mwayi wambiri wophulika, chifukwa chifukwa cha kuchepa kwa maselo omwe amachititsa kuti mafupa apangike ndikuwonongeka, mafupa amakhala osalimba.

Zizindikiro za osteopetrosis ndizokhudzana ndi kuti pali mafupa ambiri mthupi, omwe angapangitse kusintha mthupi lonse, zizindikilo zazikulu ndi izi:

• Masomphenya olakwika;
• Kuvuta kumva;
• Matenda opatsirana a mano ndi nkhama;
• Kukulitsa chiwindi ndi ndulu, zomwe zimapangitsa kusintha kwa maselo amwazi;
• Kusintha kwa chitukuko cha neuronal;
• Kuchedwa kubadwa kwa mano;
• Kuwonjezeka kwachangu.

Matenda a osteopetrosis amapangidwa ndi a orthopedist kudzera pakuyesa zithunzi monga X-ray ndi bone densitometry, komwe ndi kafukufuku wosavuta komanso wopanda zowawa womwe cholinga chake ndi kutsimikizira kuchuluka kwa mafupa a munthuyo, kulola kuyesa kuwonongeka kwa mafupa, mwachitsanzo. Mvetsetsani chomwe osteopetrosis ndi momwe zimachitikira.

Komabe, kuti atsimikizire mtundu ndi zovuta za osteopetrosis, adokotala amathanso kuyitanitsa mayeso ena opatsirana, monga computed tomography kapena maginito ojambula zithunzi kuti awone kupezeka kwa zotupa m'ziwalo zina monga maso ndi makutu, kuphatikiza pakuyezetsa magazi.

Zifukwa za osteopetrosis

Osteopetrosis amayamba chifukwa cha zofooka mumtundu umodzi kapena zingapo zomwe zimayambitsa kupangika kwa ma osteoclast, omwe ndi maselo omwe amachotsa mafupa akale ndikulowa m'malo atsopano, athanzi. Kutengera komwe magwero amasinthidwe adachokera, mtundu wa osteopetrosis umatha kusiyanasiyana:

• Malignant ubwana osteopetrosis: mwanayo ali ndi matenda kuyambira atabadwa chifukwa cha zolakwika m'matenda obadwa nawo kuchokera kwa abambo ndi amayi;
• Wamkulu osteopetrosis: osteopetrosis imangopezeka muubwana kapena ukalamba, chifukwa cha majini omwe asinthidwa kuchokera kwa abambo kapena amayi okha.

Pankhani ya wamkulu osteopetrosis, kusintha kwa majini kungayambitsenso kusintha, osalandira cholowa cha makolo.

Momwe mankhwalawa amachitikira

Chithandizo cha osteopetrosis chiyenera kutsogozedwa ndi gulu la akatswiri angapo azaumoyo, monga dokotala wa ana, orthopedist, hematologist, endocrinologist ndi physiotherapist.

Pakadali pano, chithandizo chothandiza kwambiri cha osteopetrosis ndikumuika m'mafupa, popeza ma cell omwe amalembedwa amapangidwa mgululi. Chifukwa chake, pakuchita kumuika, ndizotheka kuwongolera magwiridwe antchito am'magazi omwe amachititsa kuti mafupa apangidwe ndikuwonongeka, akumenyana ndi osteopetrosis. Mvetsetsani momwe kusintha kwa mafupa kumachitikira.

Ngakhale kumuika fupa lamankhwala ndi njira yovomerezeka yochiritsira matendawa, mankhwala ena atha kulimbikitsidwa kuti athandizire kupumula kwa zizindikilo, monga:

• Jekeseni wa Interferon gamma-1b, omwe ndi mankhwala omwe amatha kuchepetsa kukula kwa matendawa;
• Kudya kwa Kalcitriol, yomwe ndi mtundu wa vitamini D womwe umathandizira kupangitsa kuti mafupa akule bwino ndikuchepetsa kuchepa kwa mafupa;
• Kuyamwa kwa Prednisone, yomwe ndi mahomoni ofanana ndi cortisone omwe amatha kupititsa patsogolo kupanga maselo oteteza m'thupi, omwe amapangidwa m'mafupa;
• Physiotherapy magawo.

Adotolo angakulimbikitseninso kuti mufunsane ndi wazakudya kuti musinthe zakudya zanu kuti zizikhala ndi zakudya zomwe zimathandizira kukulitsa thupi ndi mafupa, makamaka paubwana.

Kuphatikiza apo, ndikofunikira kuyendera pafupipafupi kwa ophthalmologist, otolaryngologist ndi dokotala wa mano kuti akawone kukula ndi kuwoneka kotheka kwa zotupa zina kapena zolakwika m'maso, mano, mphuno, makutu ndi mmero, mwachitsanzo.