Chithandizo cha HIV: ndi mankhwala ati omwe akuwerengedwa

Zamkati

• 1. Cocktail mu njira imodzi yokha
• 2. Kuphatikiza ma antiretrovirals, mchere wagolide ndi nicotinamide
• 3. Chithandizo cha katemera kwa anthu omwe ali ndi HIV
• 4. Chithandizo ndi timinofu ta tsinde
• 5. Kugwiritsa ntchito PEP
• 6. Mankhwala a Gene ndi nanotechnology
• Chifukwa Edzi ilibe mankhwala

Pali kafukufuku wasayansi wambiri wokhudza kuchiza Edzi ndipo pazaka zapitazi kupita patsogolo kambiri kwakhala kukuwonekera, kuphatikizapo kuthetseratu kachilomboka m'magazi a anthu ena, powaganizira kuti akuchiritsidwa ku HIV, ndipo amayenera kuyang'aniridwa nthawi ndi nthawi kuti atsimikizire mankhwala.

Ngakhale pali kale mankhwala ena, kafukufuku wothana ndi kachilombo ka HIV akupitilizabe, chifukwa chithandizo chomwe chimagwira munthu wina sichingakhale cha wina, ngakhale chifukwa kachilomboko kamatha kusintha mosavuta, komwe kumapangitsa kwambiri chithandizo chovuta.

Zina mwazomwe zikuchitika pokhudzana ndi kuchiza kachilombo ka HIV ndi izi:

1. Cocktail mu njira imodzi yokha

Pofuna kuchiza HIV ndikofunikira kugwiritsa ntchito mitundu itatu yamankhwala tsiku lililonse. Kupambana pankhaniyi kunali kukhazikitsa njira ya 3-in-1, yomwe imaphatikiza mankhwala atatu mu kapisozi kamodzi. Dziwani zambiri za mankhwala atatu mwa 1 a Edzi pano.

Mankhwalawa, amalephera kuthetsa mavairasi a HIV mthupi, koma amachepetsa kuchuluka kwa ma virus, ndikusiya HIV osadziwika. Izi sizikuyimira chithandizo chotsimikizika cha HIV, chifukwa kachilomboka zikawona momwe mankhwala amathandizira, amabisala m'malo omwe mankhwala sangathe kulowa, monga ubongo, thumba losunga mazira ndi machende. Chifukwa chake, munthu akasiya kumwa mankhwala a HIV, amachulukanso mwachangu.

2. Kuphatikiza ma antiretrovirals, mchere wagolide ndi nicotinamide

Chithandizo chophatikiza zinthu zosiyanasiyana 7 chakhala ndi zotsatira zabwino chifukwa zimagwirira ntchito limodzi kuti kachilombo ka HIV katuluke mthupi. Zinthu izi zimatha kuthana ndi ma virus omwe ali mthupi, amakakamiza ma virus omwe abisala m'malo monga ubongo, mazira ndi machende kuti abwererenso, ndikukakamiza ma cell omwe ali ndi virus kuti adziphe.

Kafukufuku wokhudza anthu akuchitika motere, koma maphunzirowa sanamalizidwe.Ngakhale adachotsa ma virus ambiri otsalira, sikunali kotheka kuthetseratu ma virus a HIV. Amakhulupirira kuti izi zitatheka, kufufuza kwina kudzafunikabe chifukwa munthu aliyense angafunike mankhwala ake. Imodzi mwa njira zomwe zikuwerengedwa ndikupanga ma dendritic cell. Dziwani zambiri zamaselowa pano.

3. Chithandizo cha katemera kwa anthu omwe ali ndi HIV

Katemera wachithandizo wapangidwa yemwe amathandiza thupi kuzindikira maselo omwe ali ndi kachilombo ka HIV omwe amayenera kugwiritsidwa ntchito limodzi ndi mankhwala otchedwa Vorinostat, omwe amachititsa ma cell omwe 'akugona' mthupi.

Pa kafukufuku yemwe adachitika ku United Kingdom, wodwala adatha kuthana ndi kachirombo ka HIV, koma ena onse omwe sanatenge nawo gawo 49 sanakhale ndi zotsatira zofananira chifukwa chake pakufunika kafukufuku wambiri pamagwiridwe awo kufikira njira yothandizila itapangidwa. yokhoza kugwiritsidwa ntchito padziko lonse lapansi. Ichi ndichifukwa chake kafukufuku wina adzachitika motere m'zaka zikubwerazi.

4. Chithandizo ndi timinofu ta tsinde

Chithandizo china, chokhala ndi maselo am'madzi, chakwanitsanso kuthana ndi kachilombo ka HIV, koma popeza chimakhudza njira zovuta kwambiri, sichingagwiritsidwe ntchito pamlingo waukulu chifukwa ndi mankhwala ovuta komanso owopsa, chifukwa pafupifupi 1 mwa 5 omwe amalandira amamwalira panthawiyi.

Timothy Ray Brown anali wodwala woyamba kulandira chithandizo cha Edzi atadulidwa mafupa kuti amuchiritse khansa ya m'magazi ndipo atatha kuchita izi kuchuluka kwa ma virus ake kumachepa kwambiri mpaka pomwe mayeso aposachedwa atsimikizira kuti alibe kachilombo ka HIV ndipo angathe kunenedwa kuti ndi munthu woyamba kuchiritsidwa ku Edzi padziko lapansi.

Timothy adalandira maselo am'magazi kuchokera kwa munthu yemwe adasinthidwa mwanjira inayake kuti 1% yokha ya anthu kumpoto kwa Europe ali ndi: Kusapezeka kwa CCR5 receptor, zomwe zimamupangitsa kukhala wolimbana ndi kachilombo ka HIV. Izi zidalepheretsa wodwalayo kupanga maselo omwe ali ndi HIV ndipo, ndi chithandizo, maselo omwe anali ndi kachilombo kale adachotsedwa.

5. Kugwiritsa ntchito PEP

Post-exposure prophylaxis, yotchedwanso PEP, ndi mtundu wamankhwala omwe amaphatikizapo kugwiritsa ntchito mankhwala atangochita zoopsa, momwe munthuyo atha kutenga kachilomboka. Monga munthawi yaposachedwa pambuyo pakhalidweli pali ma virus ochepa omwe akuyenda m'magazi, pali mwayi woti 'muchiritse'. Izi zikutanthauza kuti, mwamwambowo munthuyo anali ndi kachirombo ka HIV koma analandira chithandizo msanga ndipo izi zinali zokwanira kuthetsa kachirombo ka HIV.

Ndikofunika kuti kugwiritsa ntchito mankhwalawa kumachitika m'maola awiri oyambilira kuwonekera, chifukwa izi ndizothandiza kwambiri. Ngakhale zili choncho, ndikofunikira kuyesedwa kuti mupeze kachilombo ka HIV patatha masiku 30 ndi 90 mutagonana mosadziteteza.

Mankhwalawa amachepetsa mwayi wopatsirana pogonana ndi 100% komanso 70% pogwiritsa ntchito masingano omwe agawana nawo. Komabe, kugwiritsa ntchito kwake sikukutanthauza kufunikira kogwiritsa ntchito kondomu moyandikana kwambiri, komanso sikupatula njira zina zopewera HIV.

6. Mankhwala a Gene ndi nanotechnology

Njira ina yothetsera kachilombo ka HIV ndi kudzera mu chithandizo cha majini, chomwe chimakhala chophatikiza kusintha kwa ma virus omwe ali mthupi, m'njira yomwe imalepheretsa kuchulukana kwake. Nanotechnology ingathandizenso ndipo imagwirizana ndi njira yomwe ingatheke kuyika njira zonse zolimbirana ndi kachilomboka mu kapisozi kamodzi kokha, kamene kamayenera kutengedwa ndi wodwalayo kwa miyezi ingapo, pokhala mankhwala othandiza kwambiri osavulaza .

Chifukwa Edzi ilibe mankhwala

Edzi ndi matenda owopsa omwe sanachiritsidwebe, koma pali mankhwala omwe angachepetse kuchuluka kwa ma virus ndikutalikitsa moyo wa munthu yemwe ali ndi HIV, ndikukhala moyo wabwino.

Pakadali pano chithandizo cha kachilombo ka HIV pamlingo waukulu chikuchitika ndikugwiritsa ntchito malo ogulitsa, omwe, ngakhale sangathe kuthana ndi kachilombo ka HIV m'magazi, amatha kuwonjezera chiyembekezo cha moyo wa munthuyo. Dziwani zambiri za malo ogulitsira awa: Chithandizo cha Edzi.

Chithandizo chenicheni cha Edzi sichinapezeke, komabe chili pafupi, ndipo ndikofunikira kuti odwala omwe amaonedwa kuti achiritsidwa matendawa aziwunikidwa nthawi ndi nthawi kuti awone momwe chitetezo chamthupi chikuyendera komanso ngati pali chizindikiro chilichonse chosonyeza kupezeka kwa kachilombo ka HIV.

Amakhulupirira kuti kutha kwa kachirombo ka HIV kungakhale kokhudzana ndi kuyendetsa bwino chitetezo cha mthupi ndipo kungachitike thupi la munthu likatha kuzindikira kachilomboka ndi kusintha kwake konse, kuthana nalo kwathunthu, kapena pogwiritsa ntchito matekinoloje atsopano kuti cholinga chawo sikungolimbikitsa chitetezo cha mthupi, monga momwe zimakhalira ndi ma gene ndi nanotechnology, omwe amagwira ntchito m'njira zosiyanasiyana.