Dermatitis Herpetiformis ndi Kusagwirizana kwa Gluten

Zamkati

• Zithunzi za dermatitis herpetiformis
• Nchiyani chimayambitsa dermatitis herpetiformis?
• Ndani ali pachiwopsezo cha dermatitis herpetiformis?
• Kodi zizindikiro za dermatitis herpetiformis ndi ziti?
• Kodi dermatitis herpetiformis imapezeka bwanji?
• Kodi ndi mankhwala ati omwe amapezeka a dermatitis herpetiformis?
• Kodi zovuta za dermatitis herpetiformis ndi ziti?
• Kodi chiyembekezo cha nthawi yayitali cha dermatitis herpetiformis ndi chiyani?

Kodi dermatitis herpetiformis ndi chiyani?

Kukhwima, kuphulika, kutentha kwa khungu, dermatitis herpetiformis (DH) ndizovuta kukhala nazo. Kutupa ndi kuyabwa kumachitika pazitsulo, mawondo, khungu, kumbuyo, ndi matako. Kuphulika kumeneku kumawonetsa kusalekerera kwa gluteni, komwe kumatha kukhala kokhudzana ndi vuto lalikulu lomwe limadziwika kuti matenda a leliac. DH nthawi zina amatchedwa matenda a Duhring kapena zotupa za gluten. Anthu omwe ali ndi vutoli ayenera kudya zakudya zopanda thanzi.

Zithunzi za dermatitis herpetiformis

Nchiyani chimayambitsa dermatitis herpetiformis?

Kuchokera pakumveka kwa dzinalo, anthu ambiri amaganiza kuti kuthamanga uku kumayambitsidwa ndi mtundu wina wa kachilombo ka herpes. Izi sizili choncho, chifukwa sizikugwirizana ndi herpes. Dermatitis herpetiformis imapezeka mwa anthu omwe ali ndi matenda a leliac. Matenda a Celiac (omwe amatchedwanso kuti celiac sprue, kusagwirizana kwa gluten, kapena matenda osokoneza bongo a gluten) ndi matenda omwe amayamba chifukwa cha tsankho. Gluten ndi mapuloteni omwe amapezeka mu tirigu, rye, ndi barele. Nthawi zina imapezekanso mu oats omwe adakonzedwa m'mitengo yomwe imagwira mbewu zina.

Malinga ndi National Institutes of Health (NIH), 15 mpaka 25 peresenti ya anthu omwe ali ndi matenda a leliac ali ndi DH. Matenda a Celiac amathanso kupweteketsa m'mimba, kudzimbidwa, nseru, ndi kusanza. Anthu omwe ali ndi DH nthawi zambiri alibe zizindikiro zilizonse zam'mimba. Komabe, ngakhale sakukumana ndi zizindikiro zilizonse zamatumbo, 80 peresenti kapena kupitilira apo anthu omwe ali ndi DH amakhalabe ndi vuto la m'mimba, makamaka ngati adya chakudya chomwe chili ndi mchere wambiri, malinga ndi National Foundation for Celiac Awareness (NFCA).

Kuwonongeka kwa m'mimba ndi zotupa zimachitika chifukwa cha mapuloteni amtundu wa gluten omwe ali ndi mtundu wina wa antibody wotchedwa immunoglobulin A (IgA). Thupi lanu limapanga ma antibodies a IgA kuti amenyane ndi mapuloteni a gluten. Ma antibodies a IgA akaukira gilateni, amawononga matumbo omwe amakulolani kuyamwa mavitamini ndi michere. Kumva kwa gluteni nthawi zambiri kumachitika m'mabanja.

Zomwe zimapangidwa IgA ikamamatira ku gluten kenako imalowa m'magazi, pomwe imayamba kutseka mitsempha yaying'ono yamagazi, makamaka yomwe ili pakhungu. Maselo oyera amakopeka ndi ma clogs awa. Maselo oyera amatulutsa mankhwala otchedwa "complement" omwe amayambitsa zotupa, zotupa.

Ndani ali pachiwopsezo cha dermatitis herpetiformis?

Matenda a Celiac amatha kukhudza aliyense, koma amakhala ofala kwambiri kwa anthu omwe ali ndi wachibale wina yemwe ali ndi matenda a leliac kapena DH.

Ngakhale azimayi ambiri kuposa amuna amapezeka kuti ali ndi matenda a leliac, amuna amatha kukhala ndi DH kuposa akazi, malinga ndi NIH. Kuthamanga kumayambira mzaka 20 kapena 30, ngakhale kumatha kuyambira ali mwana. Vutoli limapezeka kwambiri ndi anthu ochokera ku Europe. Sizimakhudza kwenikweni anthu ochokera ku Africa kapena ku Asia.

Kodi zizindikiro za dermatitis herpetiformis ndi ziti?

DH ndi imodzi mwaziphuphu zoyipa kwambiri zotheka. Malo omwe amapezeka pafupipafupi ndi awa:

• zigongono
• mawondo
• kutsikira kumbuyo
• tsitsi
• kumbuyo kwa khosi
• mapewa
• matako
• khungu

Ziphuphu nthawi zambiri zimakhala zofanana komanso mawonekedwe mbali zonse ziwiri za thupi ndipo nthawi zambiri zimabwera ndikupita.

Musanaphulike kwathunthu, mutha kumva kuti khungu m'dera lomwe limakonda kuphulika limayaka kapena kuyabwa. Ziphuphu zomwe zimawoneka ngati ziphuphu zodzaza ndi madzi owoneka bwino zimayamba kupangika. Izi zimakanda mwachangu. Ziphuphu zimachira m'masiku ochepa ndikusiya chizindikiro chofiirira chomwe chimatha milungu ingapo. Koma ziphuphu zatsopano zikupitirizabe kupangika pamene zakale zimachira. Izi zitha kupitilira kwa zaka zambiri, kapena zimatha kukhululukidwa kenako nkubwerera.

Ngakhale zizindikilozi zimakonda kuphatikizika ndi dermatitis herpetiformis, zimatha kuyambanso chifukwa cha khungu lina monga atopic dermatitis, zopweteketsa kapena zosagwirizana ndi dermatitis, psoriasis, pemphigoid, kapena mphere.

Kodi dermatitis herpetiformis imapezeka bwanji?

DH imapezeka bwino kwambiri ndi khungu. Dokotala amatenga khungu pang'ono ndikulipenda ndi makina oonera zinthu zing'onozing'ono. Nthawi zina, mayeso owunika a immunofluorescence amachitika, pomwe khungu lozungulira zotupa limadetsedwa ndi utoto womwe ungawonetse kupezeka kwa ma anti-IgA. Khungu la khungu limathandizanso kudziwa ngati zizindikirazi zimayambitsidwa ndi khungu lina.

Kuyezetsa magazi kuti muwone ngati ma antibodies m'magazi amathanso kuchitidwa. Matenda a m'mimba amatha kuchitidwa kuti atsimikizire kupezeka kwa kuwonongeka chifukwa cha matenda a leliac.

Ngati matendawa sadziwika, kapena matenda ena atha, mayeso ena atha kuchitidwa. Kuyezetsa magazi ndi njira yabwino kwambiri yozindikiritsa matenda opatsirana a dermatitis, omwe ndi omwe amachititsa zizindikilo zofanana ndi dermatitis herpetiformis.

Kodi ndi mankhwala ati omwe amapezeka a dermatitis herpetiformis?

DH imatha kuchiritsidwa ndi maantibayotiki otchedwa dapsone. Dapsone ndi mankhwala amphamvu okhala ndi zovuta zoyipa. Mlingowo uyenera kuwonjezeka pang'onopang'ono kwa miyezi ingapo isanakwane.

Anthu ambiri amawona mpumulo potenga dapsone, koma zoyipa zimatha kuphatikiza:

• mavuto a chiwindi
• kutengeka ndi kuwala kwa dzuwa
• kuchepa kwa magazi m'thupi
• kufooka kwa minofu
• zotumphukira za m'mitsempha

Dapsone amathanso kukhala ndi mayanjano olakwika ndi mankhwala ena, monga aminobenzoate potaziyamu, clofazimine, kapena trimethoprim.

Mankhwala ena omwe angagwiritsidwe ntchito ndi tetracycline, sulfapyridine, ndi mankhwala osokoneza bongo. Izi sizothandiza kwenikweni kuposa dapsone.

Mankhwala othandiza kwambiri omwe alibe zotsatirapo zake ndi kutsatira mosamalitsa zakudya zopanda thanzi. Izi zikutanthauza kuti muyenera kupewa zakudya, zakumwa, kapena mankhwala okhala ndi izi:

• tirigu
• rye
• balere
• phala

Ngakhale kuti chakudyachi chimakhala chovuta kutsatira, chimakhala ndi zotsatira zabwino kwambiri paumoyo wanu ngati muli ndi matenda a leliac. Kuchepetsa kudya kwa gluteni kumathandizira kuchepetsa kuchuluka kwa mankhwala omwe muyenera kumwa.

Kodi zovuta za dermatitis herpetiformis ndi ziti?

Anthu omwe ali ndi matenda a DH komanso matenda a leliac omwe sathandizidwe akhoza kukhala ndi chiopsezo chachikulu cha khansa yam'mimba chifukwa chotupa m'matumbo. Kuperewera kwa mavitamini ndi kuchepa kwa magazi kumathanso kukhala vuto ngati matumbo samayamwa michere moyenera.

Popeza DH ndimatenda amthupi okhaokha, apeza kuti imakhudzidwanso ndi mitundu ina yamatenda amthupi okha. Izi zikuphatikiza:

• hypothyroidism
• vitiligo
• lembani 1 matenda a shuga
• myasthenia gravis
• Matenda a Sjögren
• nyamakazi

Kodi chiyembekezo cha nthawi yayitali cha dermatitis herpetiformis ndi chiyani?

DH ndi matenda amoyo wonse. Mutha kupita kukakhululukidwa, koma nthawi iliyonse mukakumana ndi gilateni, mutha kuphulika. Popanda chithandizo, DH ndi matenda a leliac angayambitse mavuto ambiri azaumoyo, kuphatikizapo kuperewera kwama vitamini, kuchepa kwa magazi m'thupi, ndi khansa ya m'mimba.

Kuchiza ndi dapsone kumatha kuletsa ziwombankhanga m'malo mwachangu. Komabe, kuwonongeka kwa m'matumbo komwe kumayambitsidwa ndi matenda a leliac kumatha kuthandizidwa ndikungodya zakudya zopanda thanzi. Onetsetsani kuti mukukambirana ndi dokotala kapena katswiri wazakudya pazakudya zilizonse.