Kodi Ndingakhale Ndi Chipatso Champhesa Ndikugwiritsa Ntchito Metformin?

Zamkati

• Kodi metformin ndi chiyani?
• Momwe kulumikizirana kwa mankhwala ndi zipatso zamtengo wapatali kumagwirira ntchito
• Ndi mankhwala ati omwe amalumikizana ndi zipatso zamphesa?
• Kodi zipatso zamphesa zimakhudza bwanji metformin?
• Zinthu zina zomwe muyenera kupewa mukakhala pa metformin
• Momwe mphesa zimathandizira anthu omwe ali ndi matenda ashuga
• Tengera kwina

Mu Meyi 2020, adalimbikitsa kuti ena opanga metformin awonjezere kutulutsa ena mwa mapiritsi awo kumsika waku US. Izi ndichifukwa choti mulingo wosavomerezeka wa khansa yotenga khansa (wothandizira khansa) udapezeka m'mapiritsi ena a metformin. Ngati mukumwa mankhwalawa, itanani woyang'anira zaumoyo wanu. Adzakulangizani ngati mupitiliza kumwa mankhwala anu kapena ngati mukufuna mankhwala atsopano.

Mankhwala ambiri, monga ma statins ndi ma antihistamines, amalumikizana molakwika ndi manyumwa. Metformin imagwiritsidwa ntchito pochiza matenda amtundu wa 2.

Kodi kukhala ndi zipatso zamphesa mukamamwa metformin kumabweretsa zovuta zina? Pali kafukufuku wochepa, koma izi ndi zomwe muyenera kudziwa.

Kodi metformin ndi chiyani?

Metformin ndi mankhwala omwe amapatsidwa kuti athetse matenda ashuga amtundu wa 2. Anthu omwe ali ndi matenda a shuga amtundu wa 2 sangathe kugwiritsa ntchito insulini mwachizolowezi. Izi zikutanthauza kuti sangathe kuwongolera kuchuluka kwa shuga m'magazi awo. Metformin imathandiza anthu omwe ali ndi matenda a shuga amtundu wa 2 kuwongolera kuchuluka kwa shuga m'magazi awo m'njira zingapo, kuphatikiza:

• Kuchepetsa kuchuluka kwa shuga komwe thupi lanu limamwa kuchokera pachakudya
• kuchepetsa kuchuluka kwa shuga wopangidwa ndi chiwindi
• kukulitsa kuyankha kwa thupi lanu ku insulini yomwe imapanga mwachilengedwe

Metformin sichingayambitse vuto lalikulu komanso lowopsa lotchedwa lactic acidosis. Anthu omwe ali ndi vuto la chiwindi, impso, kapena mtima ayenera kupewa kumwa metformin.

Momwe kulumikizirana kwa mankhwala ndi zipatso zamtengo wapatali kumagwirira ntchito

Pali zoposa zomwe zimadziwika kuti zimalumikizana ndi zipatso zamphesa. Mwa mankhwalawa, zimatha kubweretsa zovuta zoyipa. Mitundu yonse ya zipatso zamphesa - kuphatikiza msuzi wothyidwa kumene, kusungunuka kwa mazira, ndi zipatso zonse - zimatha kubweretsa kulumikizana kwa mankhwala.

Mankhwala ena omwe amapezeka mu zipatso za manyumwa amatha kumangirira ndi kuyambitsa ma enzyme mthupi lanu omwe amapezeka m'matumbo ndi chiwindi. Enzyme iyi imathandizira kuwononga mankhwala omwe mumamwa.

Nthawi zambiri mukamwa mankhwala pakamwa, amathyoledwa pang'ono ndi michere asanafike m'magazi anu. Izi zikutanthauza kuti mumalandira mankhwala ocheperako pang'ono m'magazi anu kuposa momwe mumadyera poyamba.

Koma enzyme ikaletsedwa - monga momwe imagwirira ntchito ndi mankhwala amphesa - pamakhala mankhwala ochulukirapo kwambiri omwe amalowa m'magazi anu. Izi zimabweretsa chiopsezo chachikulu cha bongo. Onaninso mozama kuyanjana kwa mankhwala amphesa.

Ndi mankhwala ati omwe amalumikizana ndi zipatso zamphesa?

Malinga ndi, mitundu yotsatirayi ya mankhwala itha kukhala yolumikizana ndi manyumwa:

• ma statins, monga simvastatin (Zocor) ndi atorvastatin (Lipitor)
• mankhwala othamanga magazi, monga nifedipine (Procardia)
• mankhwala osokoneza bongo, monga cyclosporine (Sandimmune)
• corticosteroids amagwiritsidwa ntchito pochiza matenda a Crohn kapena ulcerative colitis, monga budesonide (Entocort EC)
• mankhwala omwe amachititsa mitima yachilendo, monga amiodarone (Pacerone)
• antihistamines, monga fexofenadine (Allegra)
• mankhwala ena odana ndi nkhawa, monga buspirone (BuSpar)

Madzi amphesa samakhudza mankhwala aliwonse m'magulu omwe ali pamwambapa. Kulumikizana ndi msuzi wamphesa ndizomwe zimayenderana ndi mankhwala, osati mankhwala.

Mukayamba mankhwala atsopano, ndikofunikira kuti mufunse dokotala kapena wamankhwala ngati mungathe kudya zipatso zamphesa kapena zogulitsa zipatso.

Kodi zipatso zamphesa zimakhudza bwanji metformin?

Ndikofunika kudziwa kuti metformin sikuphwanyidwa ndi enzyme yofanana ndi mankhwala omwe atchulidwa pamwambapa. Sichikusinthidwa ndi thupi lanu ndikuchotsedwa mumkodzo wanu.

Pali zochepa zopezeka momwe kukhala ndi zipatso zamphesa mukamamwa metformin kumakhudza anthu omwe ali ndi matenda amtundu wa 2.

A adakambirana za zipatso za mphesa ndi metformin mu makoswe osavomerezeka. Makoswe ena adapezeka ndi madzi amphesa ndi metformin. Ena adakumana ndi metformin yokha. Ofufuzawo apeza kuti kuwonjezeka kwa kuchuluka kwa lactic acid mu makoswe omwe amapezeka mumadzi amphesa ndi metformin.

Ochita kafukufuku anaganiza kuti madzi amphesa amathandizira kukulitsa metformin m'chiwindi. Izi, nawonso, zidapangitsa kuchuluka kwa kupanga lactic acid. Chifukwa cha ichi, ofufuzawo akuti kumwa madzi amphesa kumatha kubweretsa chiopsezo chachikulu cha lactic acidosis mwa anthu omwe amatenga metformin.

Komabe, zotsatirazi zidawonedwa mu makoswe osagwirizana ndi shuga, osati mwa anthu omwe ali ndi matenda amtundu wa 2. Mpaka pano, sipanakhalepo kafukufuku wina mwa anthu omwe akuwonetsa kuti kutenga metformin ndi msuzi wamphesa kumabweretsa lactic acidosis.

Zinthu zina zomwe muyenera kupewa mukakhala pa metformin

Kutenga mankhwala ena mukamamwa metformin kumatha kuonjezera chiopsezo chokhala ndi lactic acidosis. Muyenera kudziwitsa dokotala ngati mukumwa mankhwala aliwonse awa:

• okodzetsa, monga acetazolamide
• corticosteroids, monga prednisone
• mankhwala a kuthamanga kwa magazi, monga amlodipine (Norvasc)
• anticonvulsants, monga topiramate (Topamax) ndi zonisamide (Zonegran)
• njira zakulera zam'kamwa
• mankhwala oletsa antipsychotic, monga chlorpromazine

Pewani kumwa mowa wambiri mukakhala pa metformin. Kumwa mowa mukamamwa metformin kumawonjezera chiopsezo chokhala ndi shuga wotsika kapena lactic acidosis.

Malinga ndi University of Michigan, muyenera kupewa kudya zakudya zopatsa mphamvu mukatenga metformin. Izi ndichifukwa choti fiber imatha kumangirira kumankhwala osokoneza bongo ndikuchepetsa kuchepa kwawo. Maseŵera a Metformin amachepetsedwa akatengedwa ndi fiber yambiri (kuposa 30 milligrams patsiku).

Malangizo ena azakudya za anthu odwala matenda ashuga ndi awa:

• Phatikizani chakudya chomwe chimachokera ku masamba, zipatso, ndi mbewu zonse. Onetsetsani kuti mumayang'anira momwe mumadya, chifukwa izi zimakhudza shuga wanu wamagazi.
• Pewani chakudya chomwe chili ndi mafuta ambiri. M'malo mwake, idyani mafuta ochokera ku nsomba, mtedza, ndi mafuta. Nazi njira 10 zowonjezera mafuta athanzi pazakudya zanu.
• Kudya mamiligalamu 25 mpaka 30 a fiber tsiku lililonse kungathandize kuchepetsa magazi m'magazi. Onani mndandanda wazakudya 22 zapamwamba kwambiri kuti muyambe.
• Pewani sodium. Yesetsani kumwa zosakwana mamiligalamu 2,300 patsiku.

Momwe mphesa zimathandizira anthu omwe ali ndi matenda ashuga

Kumwa msuzi wamphesa kungakhale kopindulitsa ngati muli ndi matenda ashuga.

Anawonetsa kuti kukonzekera zakumwa za madzi amphesa omveka bwino kumachepetsa kusala kudya kwa glucose ndi kunenepa. Zotsatira zomwe zimawonedwa zinali zofanana ndi zotsatira za metformin. Panalibe zotsatira zabwino pamene madzi amphesa amphesa ndi metformin adayesedwa limodzi.

Ngakhale ndikulonjeza, ndikofunikira kuzindikira kuti izi zidapangidwa mu mbewa ya matenda ashuga.

Udindo wa zipatso za manyumwa pazakudya ndi kulumikizana ndi mankhwala akuwonetsanso kuti zipatso zamtengo wapatali zimakhudzana ndi kuchepa kwa thupi komanso kupewetsa mphamvu ya insulin. Kuphatikiza apo, kuwunikiraku kunanenanso kuti gulu la madzi amphesa (naringin) lapezeka kuti limathandizira hyperglycemia ndi cholesterol m'mtundu wachiwiri wa nyama ya shuga. Dziwani zambiri zakukhala ndi matenda ashuga komanso cholesterol.

Tengera kwina

Zipatso zamphesa zimayambitsa kusamvana ndi mankhwala ena. Komabe, palibe maphunziro omwe amadya madzi amphesa akamamwa metformin adadzetsa mavuto mwa anthu.

Pali umboni wina woyesera woyesera kuti kuphatikiza zipatso za manyumwa muzakudya zanu zitha kuthandiza kulimbikitsa kuchepa thupi komanso kuchepetsa kusala kwa glucose.

Ngati mukumwa metformin ndipo mukuda nkhawa ndi momwe mungagwiritsire ntchito mankhwala osokoneza bongo kapena kugwiritsa ntchito mankhwala osokoneza bongo, lankhulani ndi omwe amakuthandizani.