Kafukufuku Watsopano pa Endometriosis: Zomwe Muyenera Kudziwa

Zamkati

• Zomwe zaposachedwa pakuchiza endometriosis
• Mankhwala atsopano amlomo
• Zosankha zochitira opareshoni ndi mayeso azachipatala akubwera
• Zatsopano pakuzindikira endometriosis
• Kafukufuku wowonjezera wa endometriosis posachedwa
• Makina omwe amasinthiranso
• Mankhwala a Gene
• Kutenga

Chidule

Endometriosis imakhudza azimayi pafupifupi. Ngati mukukhala ndi endometriosis, mutha kuchitapo kanthu kuti muchepetse zizindikilo za vutoli. Pakadali pano palibe mankhwala, koma asayansi akugwira ntchito molimbika kuphunzira endometriosis ndi momwe angachiritsidwire bwino.

M'zaka zaposachedwa, kafukufuku wochulukirapo wafufuza zomwe zingayambitse endometriosis, njira zosasokoneza zomwe zimagwiritsidwa ntchito pozindikira vutoli, komanso njira zamankhwala zazitali. Pemphani kuti mudziwe zamtsogolo zatsopano.

Zomwe zaposachedwa pakuchiza endometriosis

Kusamalira ululu ndicho cholinga chachikulu cha mankhwala ambiri a endometriosis. Mankhwala awiri opatsirana ndi owerengera komanso othandizira ma hormone nthawi zambiri amalimbikitsidwa. Kuchita opaleshoni ndichonso njira yothandizira.

Mankhwala atsopano amlomo

M'chilimwe cha 2018, US Food and Drug Administration (FDA) idavomereza mdani woyamba wamlomo otulutsa gonadotropin-release hormone (GnRH) kuti athandize azimayi omwe ali ndi ululu wopweteka kwambiri kuchokera ku endometriosis.

Elagolix ndi. Zimagwira ntchito poletsa kupanga estrogen. Mahomoni a estrogen amathandizira kukulira kwa mabala a endometrial komanso zizindikilo zosasangalatsa.

Ndikofunikira kudziwa kuti omwe akutsutsana ndi GnRH kwenikweni amayika thupi kuti lithe kusamba. Izi zikutanthauza kuti zotsatirapo zimatha kuphatikizira kuchepa kwa mafupa, kutentha, kapena kuuma kwa ukazi, pakati pa ena.

Zosankha zochitira opareshoni ndi mayeso azachipatala akubwera

Endometriosis Foundation of America imawona kuti opaleshoni ya laparoscopic ndiyo njira yagolide yochizira matendawa. Cholinga cha opaleshoniyi ndi kuchotsa zotupa za endometrial posungira minofu yathanzi.

Opaleshoni itha kukhala yothandiza pochepetsa ululu wokhudzana ndi endometriosis, ikutero ndemanga mu magazini ya Women's Health. Ndizothekanso, ndi chilolezo chodziwitsidwa kale, kuti dokotalayo azichita opareshoni yochizira endometriosis ngati gawo limodzi la njira yodziwira vutoli. Kafukufuku wa 2018 wokhudza anthu opitilira 4,000 adapeza kuti opaleshoni yochotsa laparoscopic imathandizanso kuthana ndi ululu wam'mimba komanso matumbo okhudzana ndi endometriosis.

Kuyesedwa kwachipatala kwatsopano ku Netherlands kukufuna kuti opaleshoni izikhala yothandiza kwambiri. Imodzi mwa njira zamakono zopangira opaleshoni ndikuti ngati zotupa za endometriosis sizichotsedwa kwathunthu, zizindikilo zimatha kubwereranso. Izi zikachitika, opaleshoniyi angafunike kuibwereza. Kuyesedwa kwachipatala kwatsopano kukuwunika kugwiritsa ntchito kujambula kwa fluorescence kuti athandize kupewa kufunika kochitidwa maopaleshoni mobwerezabwereza.

Zatsopano pakuzindikira endometriosis

Kuchokera pamayeso amchiuno mpaka ma ultrasound mpaka opaleshoni ya laparoscopic, njira zothandiza kwambiri zodziwira endometriosis ndizowopsa. Madokotala ambiri amatha kudziwa endometriosis kutengera mbiri yazachipatala ndikuwunika. Komabe, opareshoni ya laparoscopic - yomwe imaphatikizapo kuyika kamera yaying'ono kuti muwone zipsera zam'mapapo - ndi njira yodziwikiratu yodziwira.

Endometriosis imatha kutenga zaka pafupifupi 7 mpaka 10 kuti mupeze matenda. Kuperewera kwa mayeso osazindikirika ndi chimodzi mwazifukwa zakanthawi kwakanthawi.

Izi zitha kusintha tsiku lina. Posachedwa, asayansi omwe ali ndi Feinstein Institute of Medical Research adasindikiza kafukufuku yemwe akuwonetsa kuti kuyesa pamasamba am'magazi kusamba kumatha kupereka njira yothandiza, yosasokoneza yodziwira endometriosis.

Ofufuzawa adapeza kuti maselo omwe ali m'magazi azimayi akusamba omwe ali ndi endometriosis ali ndi mawonekedwe ena. Makamaka, magazi akusamba amakhala ndi ma cell ochepa opha aziberekero ochepa. Amakhalanso ndi ma cell omwe ali ndi vuto la "decidualization," njira yomwe imakonzekeretsa chiberekero kuti chikhale ndi pakati.

Kafufuzidwe kena kofunikira. Koma ndizotheka kuti zolembazi tsiku lina zitha kupereka njira mwachangu komanso yosasokoneza yodziwitsa endometriosis.

Kafukufuku wowonjezera wa endometriosis posachedwa

Kafukufuku wokhudzana ndi matenda a endometriosis ndi chithandizo chikuchitika. Maphunziro awiri akulu - komanso sci-fi - adatuluka kumapeto kwa 2018:

Makina omwe amasinthiranso

Pakafukufuku wochokera ku Northwestern Medicine, ofufuza adapeza kuti ma cell a pluripotent stem (iPS) atha "kusinthidwa" kuti asinthe kukhala maselo abwinobwino, obwezeretsa chiberekero. Izi zikutanthauza kuti maselo achiberekero omwe amayambitsa kupweteka kapena kutupa amatha kusinthidwa ndi maselo athanzi.

Maselowa amapangidwa kuchokera pakupezeka kwa mkazi ma cell a iPS. Izi zikutanthauza kuti palibe chiopsezo chokana ziwalo, monga zilili ndi mitundu ina yosanjikiza.

Kafufuzidwe kena kofunikira. Koma pali kuthekera kwakuti chithandizo chama cell kukhala yankho lalitali ku endometriosis.

Mankhwala a Gene

Zomwe zimayambitsa endometriosis sizikudziwika. Kafukufuku wina akuwonetsa kuti kuponderezedwa kwa majini ena kutha kutengapo gawo.

Asayansi ku Yale University adafufuza kafukufuku wopeza kuti microRNA Let-7b - yomwe imayambitsa matendawa - imaponderezedwa mwa azimayi omwe ali ndi endometriosis. Yankho lake? Kupereka Let-7b kwa amayi kungathandize kuthandizira vutoli.

Pakadali pano, chithandizochi chawonetsedwa kuti chimagwira mbewa. Ochita kafukufuku adawona kuchepa kwakukulu kwa zotupa za endometrial atabaya mbewa ndi Let-7b. Kafukufuku wochuluka amafunika musanayesedwe mwa anthu.

Ngati chithandizo cha majini chithandizadi mwa anthu, ikhoza kukhala njira yopanda opaleshoni, yosasokoneza, komanso yopanda mahomoni yochizira endometriosis.

Kutenga

Ngakhale kulibe mankhwala a endometriosis, amatha kuchiritsidwa. Kafufuzidwe pamatchulidwe, zosankha zamankhwala, ndi kasamalidwe kake kakuchitika. Ngati mukufuna kuphunzira zambiri, lankhulani ndi dokotala wanu. Atha kuyankha mafunso anu ndi kukuwuzani zofunikira kuti mudziwe zambiri.