Chithandizo cha visceral leishmaniasis: mankhwala ndi chisamaliro

Zamkati

• Mankhwala ambiri ogwiritsidwa ntchito
• Kusamalira panthawi ya chithandizo
• Zizindikiro zakusintha
• Zizindikiro zakukula

Mankhwala a visceral leishmaniasis, omwe amadziwikanso kuti kala azar, amachitika, makamaka, ndi Pentavalent Antimonial Compound, masiku 20 mpaka 30, ndi cholinga chothana ndi zizindikilo za matendawa.

Visceral Leishmaniasis ndi matenda omwe amayamba ku Brazil ndi protozoanLeishmania chagasi, yomwe imafalikira ndi tizilombo tating'onoting'onoLutzomyia longipalpis ndipoLutzomyia cruzi. Matendawa amakula pang'onopang'ono ndipo amatha kukhala owopsa, chifukwa chake, pamaso pazizindikiro zomwe zimawonetsa visceral Leishmaniasis, ndikofunikira kupita kuchipatala, kuti mupeze matenda oyenera ndi chithandizo. Phunzirani zambiri za momwe mungadziwire visceral leishmaniasis.

Kuphatikiza pa mankhwala omwe amachotsa protozoan, chithandizo chamankhwala chiyenera kuphatikizira kuwongolera zovuta zamatendawa, monga kuchepa kwa magazi, kutsegula m'mimba, kuperewera kwa zakudya m'thupi, magazi ndi matenda chifukwa chakuchepa kwa chitetezo chamthupi, chifukwa izi ndi zomwe zimafooka ndipo zimatha kuyika moyo wa munthu pachiwopsezo.

Mankhwala ambiri ogwiritsidwa ntchito

Mankhwala omwe amagwiritsidwa ntchito pochiza visceral Leishmaniasis ndi Pentavalent Antimonial Compound, monga meglumine antimoniate ndi sodium stibogluconate, omwe ndi njira yofunika kwambiri yothandizira, yogwiritsidwa ntchito m'mitsempha yam'mimba kapena ya venous, masiku 20 mpaka 30. Dziwani zambiri za momwe amagwiritsidwira ntchito komanso mtengo wamankhwala omwe amagwiritsidwa ntchito kwambiri pochiza Leishmaniasis.

Nthawi zingapo, mankhwalawa amatha kuyambitsa zovuta zina, monga arrhythmias, kupweteka kwa thupi komanso kusowa chakudya, ndipo amatsutsana ndi anthu omwe ali ndi impso kapena chiwindi kulephera, mwa amayi apakati m'zaka ziwiri zoyambirira za mimba komanso milandu yomwe imawonetsa zizindikiro za kusintha kwa electrocardiogram, yotchedwa kuwonjezeka kwa nthawi ya QT.

Njira zina zosowa pakakhala kusowa kapena zotsutsana ndi mankhwalawa ndi liposomal Amphotericin B, kufalikira kwa colloidal-Amphotericin B, Pentamidines ndi ma immunomodulators, monga gamma interferon ndi GM-CSF, kuphatikiza pa Miltefosina, yomwe imathandizanso pakamwa wa leishmaniasis.

Kusamalira panthawi ya chithandizo

Musanayambe kulandira chithandizo, muyenera kusamala mosamala, kuphatikiza kuwunika ndi kukhazikika kwazomwe zimayambitsa matendawa, monga mavalidwe kapena kuthiridwa magazi, magazi ndi mavitamini m'malo mwake, ngati kuli kofunikira, kuthiridwa magazi kuchira chifukwa cha kuchepa kwa magazi m'thupi, zakudya zomanga thupi ndi zomanga thupi komanso zopatsa mphamvu kuti athetse kuperewera kwa zakudya m'thupi komanso kugwiritsa ntchito maantibayotiki kuti athetse matenda.

Chithandizochi chitha kuchitidwa kunyumba, bola ngati munthuyo atha kulandira chisamaliro chofunikira mderali ndipo amatha kupita kuchipatala kukalandira mankhwala komanso kukapimidwa kuchipatala. Kuphatikiza apo, kuchipatala kuyenera kulimbikitsidwa ngati kuli:

• Kuchepa kwa magazi m'thupi, ndi hemoglobin yosakwana 5 g / dL;
• Kutsegula m'mimba kwambiri kapena kwa nthawi yayitali;
• Kusowa zakudya m'thupi kwakukulu;
• Kukhalapo kwa magazi;
• Kutupa kwathunthu;
• Kupezeka kwa matenda ena okhudzana ndi matendawa, monga kuthamanga kwa magazi, matenda amtima, nephropathy kapena matenda a chiwindi;
• Ana ochepera miyezi isanu ndi umodzi kapena okalamba azaka zopitilira 65;
• Matendawa akabwerera mankhwala atatha kapena palibe yankho ku mankhwalawo.

Kuphatikiza apo, mankhwalawa akamalizidwa, munthuyo ayenera kutsatiridwa ndi dokotala pambuyo pa miyezi 3, 6 ndi 12 ndipo, ngati atakhazikika pakuwunika komaliza, wodwalayo amaonedwa kuti wachiritsidwa.

Zizindikiro zakusintha

Zizindikiro zakusintha zimatha kuwonekera patatha sabata yoyamba mankhwala atayamba ndipo amadziwika ndi kuchepa kwa malungo, kuchepa kwa mimba yotupa, kunenepa komanso kuchira.

Zizindikiro zakukula

Zizindikirozi ndizofala kwambiri ngati chithandizo sichinayambike mwachangu ndipo chimaphatikizapo kuwonjezeka kapena kubwereza kutentha thupi, kuchepa thupi, kufooka kosalekeza, matenda a bakiteriya mthupi ndi magazi.