Kukaniza kwa Leptin ndi Leptin: Chilichonse Chimene Muyenera Kudziwa
Zamkati
- Kumanani ndi Leptin - Hormone Yemwe Amawongolera Kulemera Kwa Thupi
- Zomwe Zimakhudza Ubongo Wanu
- Kodi Leptin Resistance Ndi Chiyani?
- Zovuta pa Kudya
- Zomwe Zimayambitsa Kukanika kwa Leptin?
- Kodi Kukana kwa Leptin Kungasinthidwe?
- Mfundo Yofunika Kwambiri
Anthu ambiri amakhulupirira kuti kunenepa ndi kutayika kumangokhudza zopatsa mphamvu komanso mphamvu.
Komabe, kafukufuku wamakono wonenepa kwambiri sagwirizana. Asayansi akunenanso kuti mahomoni otchedwa leptin amakhudzidwa ().
Leptin kukana, momwe thupi lanu silimayankhira hormone iyi, tsopano akukhulupirira kuti ndi amene amayendetsa bwino mafuta mwa anthu (2).
Nkhaniyi ikufotokoza zonse zomwe muyenera kudziwa za leptin ndi momwe zimakhudzira kunenepa kwambiri.
Kumanani ndi Leptin - Hormone Yemwe Amawongolera Kulemera Kwa Thupi
Leptin ndi mahomoni omwe amapangidwa ndimaselo amafuta amthupi ().
Nthawi zambiri amatchedwa "mahomoni okhuta" kapena "timadzi ta njala."
Cholinga chachikulu cha Leptin chili muubongo - makamaka dera lotchedwa hypothalamus.
Leptin akuyenera kuuza ubongo wanu kuti - mukakhala ndi mafuta okwanira osungidwa - simuyenera kudya ndipo mutha kuwotcha zopatsa mphamvu pamlingo woyenera (4).
Ilinso ndi ntchito zina zambiri zokhudzana ndi kubala, chitetezo chokwanira ndi magwiridwe antchito aubongo (5).
Komabe, udindo waukulu wa leptin ndikuwongolera mphamvu kwakanthawi, kuphatikiza kuchuluka kwa zopatsa mphamvu zomwe mumadya ndikugwiritsa ntchito, komanso kuchuluka kwamafuta omwe mumasunga mthupi lanu ().
Dongosolo la leptin lidasinthika kuti anthu asafe ndi njala kapena kudya mopitirira muyeso, zonse zomwe zikadakupangitsani kuti musakhale m'chilengedwe.
Masiku ano, leptin imathandiza kwambiri kuti tisafe ndi njala. Koma china chake chathyoledwa pamakina omwe amayenera kutilepheretsa kudya mopitirira muyeso.
ChiduleLeptin ndi timadzi tomwe timapangidwa ndimaselo amafuta mthupi lanu. Udindo wake waukulu ndikuwongolera kusungira mafuta ndi kuchuluka kwa ma calories omwe mumadya ndikuwotcha.
Zomwe Zimakhudza Ubongo Wanu
Leptin amapangidwa ndimaselo amafuta amthupi lanu. Akakhala ndi mafuta ochuluka m'thupi, amatulutsa leptin wochuluka ().
Leptin imanyamulidwa ndi magazi kulowa muubongo wanu, komwe amatumiza chizindikiro ku hypothalamus - gawo lomwe limayang'anira nthawi komanso kuchuluka kwa zomwe mumadya ().
Maselo amafuta amagwiritsa ntchito leptin kufotokozera ubongo wanu kuchuluka kwa mafuta omwe amakhala nawo. Milingo yambiri ya leptin imauza ubongo wanu kuti muli ndi mafuta ochuluka, pomwe otsika amauza ubongo wanu kuti malo ogulitsira mafuta ndi ochepa ndipo muyenera kudya ().
Mukamadya, thupi lanu limakwera m'mwamba, zomwe zimapangitsa kuti leptin yanu ikwere. Chifukwa chake, mumadya pang'ono ndikuwotcha kwambiri.
Mosiyana ndi izi, mukapanda kudya, mafuta a thupi lanu amatsika, ndikupangitsa kuti leptin yanu igwere. Pamenepo, mumadya zambiri ndikuwotcha pang'ono.
Dongosolo lamtunduwu limadziwika kuti njira yolankhulira yoyipa komanso yofanana ndi njira zowongolera zochitika zosiyanasiyana zakuthupi, monga kupuma, kutentha kwa thupi ndi kuthamanga kwa magazi.
ChiduleNtchito yayikulu ya leptin ndikutumiza chizindikiro chouza ubongo wanu kuchuluka kwamafuta omwe amasungidwa m'maselo amafuta amthupi lanu.
Kodi Leptin Resistance Ndi Chiyani?
Anthu omwe ali onenepa kwambiri amakhala ndi mafuta ambiri mthupi mwawo.
Chifukwa ma cell amafuta amatulutsa leptin molingana ndi kukula kwake, anthu onenepa kwambiri amakhalanso ndi leptin ().
Popeza leptin amayenera kugwira ntchito, anthu onenepa kwambiri amayenera kuchepetsa kudya. Mwanjira ina, ubongo wawo uyenera kudziwa kuti ali ndi mphamvu zambiri zosungidwa.
Komabe, kuwonetsa kwawo leptin sikungagwire ntchito. Ngakhale leptin yolemetsa imatha kupezeka, ubongo sukuziwona ().
Matendawa - omwe amadziwika kuti leptin kukana - tsopano akukhulupirira kuti ndi omwe amathandizira kwambiri kunenepa kwambiri ().
Ubongo wanu ukapanda kulandira leptin, amaganiza molakwika kuti thupi lanu likhala ndi njala - ngakhale lili ndi mphamvu zopitilira muyeso.
Izi zimapangitsa ubongo wanu kusintha machitidwe ake kuti mupezenso mafuta amthupi (, 14,). Ubongo wanu umalimbikitsa:
- Kudya zambiri: Ubongo wanu umaganiza kuti muyenera kudya kuti mupewe njala.
- Kuchepetsa kugwiritsa ntchito mphamvu: Pofuna kusunga mphamvu, ubongo wanu umachepetsa mphamvu zanu ndikupangitsani kuwotcha mafuta ochepa mukamapuma.
Chifukwa chake, kudya zochulukirapo komanso kuchita masewera olimbitsa thupi sizomwe zimayambitsa kunenepa koma zotsatira zake za kukana kwa leptin, vuto la mahomoni ().
Kwa anthu ambiri omwe ali ndi vuto la leptin kukana, kudzipereka nokha kuthana ndi chizindikiro cha njala yoyendetsedwa ndi leptin sikungatheke.
ChiduleAnthu onenepa kwambiri amakhala ndi leptin wambiri, koma chizindikiro cha leptin sichikugwira ntchito chifukwa cha vuto lotchedwa leptin resistance. Kukana kwa Leptin kumatha kuyambitsa njala ndikuchepetsa kuchuluka kwama calories omwe mumawotcha.
Zovuta pa Kudya
Kukana kwa Leptin kungakhale chifukwa chimodzi chomwe zakudya zambiri zimalephera kulimbikitsa kuchepa kwakanthawi (,).
Ngati mulibe leptin, kuchepa thupi kumachepetsabe mafuta, zomwe zimapangitsa kuti muchepetse kwambiri ma leptin - koma ubongo wanu sikuti umasinthanso mphamvu yake ya leptin.
Leptin ikatsika, izi zimapangitsa kuti munthu akhale ndi njala, azikhala ndi chilakolako chofuna kudya, achepetse chidwi chochita masewera olimbitsa thupi komanso kuchepa kwama kalori opumira (,).
Ubongo wanu umaganiza kuti muli ndi njala ndikuyambitsa njira zingapo zamphamvu kuti mupezenso mafuta amthupi omwe atayika.
Izi zikhoza kukhala chifukwa chachikulu chomwe anthu ambiri amadyera-kutaya kulemera kwakukulu kuti abwezeretse posakhalitsa pambuyo pake.
ChiduleAnthu akataya mafuta, ma leptin amachepetsa kwambiri. Ubongo wanu umatanthauzira izi ngati chizindikiro cha njala, kusintha biology yanu ndi machitidwe anu kuti mupezenso mafuta omwe adatayika.
Zomwe Zimayambitsa Kukanika kwa Leptin?
Njira zingapo zomwe zingayambitse kukana kwa leptin zadziwika.
Izi zikuphatikiza (,):
- Kutupa: Zizindikiro zotupa mu hypothalamus yanu mwina ndichofunikira kwambiri pakulimbana ndi leptin mwa nyama ndi anthu.
- Mafuta aulere aulere: Kukhala ndi mafuta omasuka aulere m'magazi anu kumatha kukulitsa ma metabolites amafuta muubongo wanu ndikusokoneza kuwonetsa kwa leptin.
- Kukhala ndi leptin yayikulu: Kukhala ndi leptin wokwera poyamba kumawoneka kuti kumayambitsa leptin kukana.
Zambiri mwazimenezi zimakwezedwa ndi kunenepa kwambiri, kutanthauza kuti mutha kutengeka ndi kunenepa kwambiri ndikukhala osagonjetsedwa ndi leptin pakapita nthawi.
ChiduleZomwe zingayambitse kukana kwa leptin zimaphatikizapo kutupa, mafuta okwera aulere komanso kuchuluka kwa leptin. Onse atatu adakwezedwa ndi kunenepa kwambiri.
Kodi Kukana kwa Leptin Kungasinthidwe?
Njira yabwino yodziwira ngati mulibe leptin ndiyo kuyang'ana pakalilole.
Ngati muli ndi mafuta ochuluka mthupi, makamaka m'mimba, ndiye kuti mumakhala osagonjetsedwa ndi leptin.
Sizikudziwika bwinobwino momwe kukana kwa leptin kungasinthire, ngakhale malingaliro ali ambiri.
Ofufuza ena amakhulupirira kuti kuchepetsa kutupa komwe kumayambitsidwa ndi zakudya kungathandize kuthana ndi leptin. Kuyang'ana kwambiri moyo wathanzi ndiyonso njira yabwino.
Pali zinthu zingapo zomwe mungachite:
- Pewani chakudya chamafuta: Zakudya zopangidwa kwambiri zimatha kusokoneza kukhulupirika kwa m'matumbo anu ndikuyendetsa kutupa ().
- Idyani CHIKWANGWANI sungunuka: Kudya michere yosungunuka kumatha kuthandizira kukulitsa thanzi lanu m'matumbo ndipo kungateteze ku kunenepa kwambiri ().
- Kuchita masewera olimbitsa thupi: Kuchita masewera olimbitsa thupi kumatha kuthandizira kusintha kwa leptin ().
- Kugona: Kugona mokwanira kumakhudzidwa ndi mavuto a leptin ().
- Tsitsani ma triglycerides anu: Kukhala ndi ma triglycerides apamwamba kumatha kuletsa mayendedwe a leptin kuchokera m'magazi anu kupita kuubongo wanu. Njira yabwino yochepetsera triglycerides ndiyo kuchepetsa kudya kwa carb (, 28).
- Idyani mapuloteni: Kudya mapuloteni ambiri kumatha kuyambitsa kuwonda, komwe kungachitike chifukwa cha kusintha kwa chidwi cha leptin ().
Ngakhale palibe njira yosavuta yochotsera leptin kukana, mutha kusintha masinthidwe amoyo wautali womwe ungasinthe moyo wanu.
ChiduleNgakhale kukana kwa leptin kumawoneka ngati kosinthika, kumakhudza kusintha kwakukulu kwakadyedwe komanso kusintha kwa moyo.
Mfundo Yofunika Kwambiri
Kukana kwa Leptin ikhoza kukhala chimodzi mwazifukwa zazikulu zomwe anthu amalemerera ndipo zimakhala zovuta kutaya.
Chifukwa chake, kunenepa kwambiri sikumayambitsidwa ndi umbombo, ulesi kapena kusowa mphamvu.
M'malo mwake, pali mphamvu zamagetsi zamagulu komanso zikhalidwe zomwe zimagwiranso ntchito. Zakudya zakumadzulo makamaka zitha kukhala zoyendetsa kwambiri kunenepa kwambiri.
Ngati mukukhudzidwa mutha kukhala osagonjetsedwa ndi leptin, pali zinthu zingapo zomwe mungachite kuti mukhale ndi moyo wathanzi - ndipo mwina kusintha kapena kusintha kukana kwanu.