Mlembi: Louise Ward
Tsiku La Chilengedwe: 6 Febuluwale 2021
Sinthani Tsiku: 11 Kuguba 2025
Anonim
Neulasta (Pegfilgrastim) Injection
Kanema: Neulasta (Pegfilgrastim) Injection

Zamkati

Neulasta ndi chiyani?

Neulasta ndi mankhwala omwe amadziwika kuti ndi mankhwala. Ikuvomerezedwa ndi FDA pazotsatira izi:

  • Kuchepetsa chiopsezo chotenga kachilombo chifukwa cha matenda otchedwa febrile neutropenia mwa anthu omwe ali ndi khansa yomwe siili ya myeloid. Kuti mugwiritse ntchito Neulasta, muyenera kumwa mankhwala ochepetsa khansa omwe angayambitse febrile neutropenia (maselo oyera azigawo oyera otchedwa neutrophils).
  • Kuchiza matenda a radiation. Mtundu wa matenda a radiation omwe Neulasta amagwiritsidwa ntchito amatchedwa hematopoietic subsyndrome.

Gulu la mankhwala a Neulasta ndi mawonekedwe

Neulasta ili ndi chinthu chimodzi chogwiritsira ntchito mankhwala: pegfilgrastim. Neulasta ali mgulu la mankhwala lotchedwa leukocyte kukula zinthu. Gulu la mankhwala ndi gulu la mankhwala omwe amagwiranso ntchito chimodzimodzi.

Neulasta imabwera m'njira ziwiri. Imodzi ndi jakisoni woyambira limodzi. Fomuyi imaperekedwa tsiku lotsatira mukalandira mankhwala a chemotherapy monga jakisoni wocheperako (jakisoni pansi pa khungu lanu).

Wopereka chithandizo chamankhwala amakupatsani jekeseni wa Neulasta, kapena mutha kudzipatsa jekeseni kunyumba mukaphunzitsidwa. Sirinjiyo imapezeka mwamphamvu imodzi: 6 mg / 0.6 mL.


Fomu yachiwiri imatchedwa Neulasta Onpro, yomwe ndi jakisoni wa thupi (OBI). Wopereka chithandizo chamankhwala azigwiritsa ntchito m'mimba mwanu kapena kumbuyo kwa mkono tsiku lomwelo mukalandira chemotherapy.

Neulasta Onpro amapereka mankhwalawa pafupifupi tsiku limodzi OBI atagwiritsidwa ntchito. Izi zikutanthauza kuti simuyenera kubwerera kuofesi ya dokotala kuti mukalandire jakisoni. Neulasta Onpro amapezeka mwamphamvu imodzi: 6 mg / 0.6 mL.

Zindikirani: Ngakhale syringe ya Neulasta itha kugwiritsidwa ntchito pochiza zinthu zonse zomwe zatchulidwa pamwambapa, Neulasta Onpro sagwiritsidwa ntchito pochiza matenda a radiation.

Kuchita bwino

Kuti mumve zambiri za momwe Neulasta imathandizira, onani gawo la "Neulasta uses" pansipa.

Neulasta generic kapena biosimilar

Neulasta amapezeka ngati mankhwala odziwika ndi dzina. Neulasta ili ndi mitundu itatu ya biosimilar: Fulphila, Udenyca, ndi Ziextenzo.

Biosimilar ndi mankhwala omwe amafanana ndi mankhwala omwe amadziwika ndi dzina. Komano, mankhwala achibadwa, ndiwo mankhwala enieni amene ali mu dzina la mankhwala.


Biosimilars amachokera ku mankhwala a biologic, omwe amapangidwa kuchokera kuzinthu zamoyo. Zodzoladzola zimadalira mankhwala omwe amapangidwa kuchokera ku mankhwala. Ma biosimilars ndi generic amakhalanso otsika mtengo poyerekeza ndi mankhwala omwe amadziwika nawo.

Neulasta ili ndi chinthu chimodzi chogwiritsira ntchito mankhwala: pegfilgrastim. Izi zikutanthauza kuti pegfilgrastim ndizomwe zimapangitsa Neulasta kugwira ntchito.

Zotsatira zoyipa za Neulasta

Neulasta imatha kuyambitsa zovuta zochepa kapena zoyipa. Mndandanda wotsatira uli ndi zina mwazovuta zomwe zingachitike mukamamwa Neulasta. Mndandandawu mulibe zovuta zonse zomwe zingachitike.

Kuti mumve zambiri paza zotsatira za Neulasta, lankhulani ndi dokotala kapena wamankhwala. Amatha kukupatsirani malangizo amomwe mungathetsere mavuto omwe angakhale ovuta.

Zindikirani: Food and Drug Administration (FDA) imatsata zotsatira zoyipa zamankhwala omwe avomereza. Ngati mukufuna kufotokozera FDA zotsatira zoyipa zomwe mudakhala nazo ndi Neulasta, mutha kutero kudzera ku MedWatch.


Zotsatira zoyipa

Zotsatira zoyipa za Neulasta zitha kuphatikiza:

  • kupweteka kwa mafupa (zambiri mu "Zotsatira zoyipa" pansipa)
  • kupweteka m'manja kapena miyendo yanu

Zambiri mwa zotsatirazi zimatha kutha masiku angapo kapena milungu ingapo. Koma ngati akula kwambiri kapena osachokapo, lankhulani ndi dokotala kapena wamankhwala.

Zotsatira zoyipa

Zotsatira zoyipa zochokera ku Neulasta sizachilendo, koma zimatha kuchitika. Itanani dokotala wanu nthawi yomweyo ngati muli ndi zovuta zina. Itanani 911 ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukukumana ndi zachipatala.

Zotsatira zoyipa komanso zizindikilo zake zimatha kuphatikiza:

  • Minyewa (kutupa kwa msempha, mtsempha wamagazi waukulu wamtima). Zizindikiro zimatha kuphatikiza:
    • kupweteka kwa msana
    • malaise (kusasangalala kapena kusakhazikika)
    • malungo
    • kupweteka m'mimba

Zotsatira zoyipa zina, zofotokozedwa mwatsatanetsatane pansipa mu "Zotsatira zoyipa," ndi izi:

  • thupi lawo siligwirizana
  • Matenda ovuta kupuma (mtundu wamapapu)
  • capillary leak syndrome (momwe mitsempha yaying'ono yamagazi imatulukira)
  • glomerulonephritis (gulu la impso)
  • leukocytosis (kuchuluka kwa maselo oyera amwazi otchedwa leukocyte)
  • nthata yotumphuka (kutsegula kwa chiwalo chotchedwa ndulu)

Zotsatira zoyipa

Mutha kudabwa kuti zovuta zina zimachitika kangati ndi mankhwalawa. Nazi zina mwazovuta zomwe zingachitike ndi kuwombera kapena chigamba cha Neulasta.

Matupi awo sagwirizana

Mofanana ndi mankhwala ambiri, anthu ena amatha kusokonezeka atalandira Neulasta. Sizikudziwika kuti ndi anthu angati omwe adakumana ndi Neulasta m'mayesero azachipatala. Koma machitidwe ambiri adachitika mwa anthu omwe adalandira mankhwala a Neulasta koyamba.

Ndipo kwa anthu ena, izi zidachitikanso patatha masiku angapo, mankhwalawa atatha. Chomatira cha acrylic chimagwiritsidwa ntchito ndi Neulasta on-body injector (OBI) ndipo chimatha kuyambitsa zovuta ngati wina ali ndi zovuta pazomatira.

Zizindikiro za kuchepa pang'ono zimatha kuphatikiza:

  • zotupa pakhungu
  • kuyabwa
  • Kutentha (kutentha ndi kufiira pakhungu lanu)

Zomwe zimayambitsa matendawa zimakhala zochepa koma ndizotheka. Zizindikiro za kuyanjana kwambiri ndi izi:

  • kutupa pansi pa khungu lanu, makamaka m'makope anu, milomo, manja, kapena mapazi
  • kutupa lilime, pakamwa, kapena pakhosi
  • kuvuta kupuma

Itanani dokotala wanu nthawi yomweyo ngati mukudwala Neulasta. Itanani 911 ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukukumana ndi zachipatala.

Kupweteka kwa mafupa

Kupweteka kwa mafupa ndi gawo lofala la Neulasta. M'maphunziro azachipatala, 31% ya anthu omwe adatenga Neulasta adanenanso zowawa zam'mafupa poyerekeza ndi 26% ya anthu omwe adatenga placebo (mankhwala osagwiritsa ntchito mankhwala).

Sizikudziwika bwinobwino chifukwa chomwe Neulasta amathandizira kupweteka kwa mafupa mwa anthu ena. Chiphunzitso chimodzi chimaphatikizapo histamine, mapuloteni omwe chitetezo chamthupi chanu chimapanga kuti chithandizire kulimbana ndi matenda.

Neulasta imalimbikitsa chitetezo cha mthupi lanu kuti apange maselo oyera oyera, zomwe zimapangitsanso kuti histamine ipangidwe. Ndipo kutulutsa kwa histamine kumalumikizidwa ndi kutupa kwa m'mafupa ndi kupweteka. Koma kafukufuku wina amafunika asanadziwike chifukwa chake Neulasta amayambitsa kupweteka kwa mafupa.

Ngati muli ndi ululu wa m'mafupa mukamagwiritsa ntchito Neulasta, uzani dokotala wanu. Amatha kukupatsirani mankhwala azowawa, monga ibuprofen kapena naproxen. Kapenanso akhoza kukusinthireni kuchipatala kupatula Neulasta.

Matenda ovuta kupuma (ARDS)

Matenda oopsa a kupuma (ARDS) ndiwotheka ku Neulasta, koma sizimachitika kawirikawiri. ARDS sinatchulidwe panthawi yamayesero azachipatala a mankhwalawa, koma vutoli lanenedwa mwa anthu ochepa omwe amatenga Neulasta kuyambira pomwe adabwera pamsika.

Ndi ARDS, mapapu anu amadzaza ndimadzimadzi ndipo sangathe kupereka mpweya wokwanira mthupi lanu lonse. Izi zitha kubweretsa mavuto ena am'mapapo monga chibayo kapena matenda.

Zizindikiro za ARDS zitha kuphatikiza:

  • chisokonezo
  • kuuma, kutsokomola
  • kumva kufooka
  • malungo
  • kuthamanga kwa magazi

ARDS ndiwopseza moyo womwe umafunikira chithandizo chamankhwala mwachangu. Ngati mukumwa Neulasta ndipo mukuvutika kupuma, kupuma mwachangu, kapena kupuma pang'ono, imbani 911 kapena mupite kuchipinda chadzidzidzi.

Matenda a capillary leak

Capillary leak syndrome ndiyowopsa koma woyipa kwambiri wa Neulasta. Sidziwika motsimikiza kuti zidachitika kangati m'maphunziro azachipatala.

Ma capillaries ndi mitsempha yaying'ono yamagazi. Matenda a capillary leak amapezeka pamene madzi ndi mapuloteni amatha kutuluka m'matumbo ndi minyewa yoyandikana nayo. Izi zimatha kuyambitsa kutsika kwa magazi ndi hypoalbuminemia (mapuloteni ochepa omwe amatchedwa albin).

Zizindikiro za capillary leak syndrome zitha kuphatikiza:

  • edema (kusungunula ndi kusungira madzi)
  • kutsegula m'mimba
  • kutopa (kusowa mphamvu)
  • kumva ludzu kwambiri
  • nseru
  • kupweteka m'mimba

Monga tafotokozera pamwambapa, capillary leak syndrome ndiyosowa, koma imatha kupha. Chifukwa chake ngati mukuganiza kuti muli ndi matenda a capillary leak syndrome mukamamwa Neulasta, itanani 911 kapena mupite kuchipinda chadzidzidzi.

Glomerulonephritis

Ngakhale kuti glomerulonephritis sichinafotokozeredwe m'maphunziro azachipatala a Neulasta, adanenedwa mwa anthu omwe adamwa mankhwalawa kuyambira pomwe adabwera pamsika.

Glomerulonephritis amatanthauza kutupa (kutupa) kwa glomeruli, komwe ndi magulu amitsempha yamagazi mu impso zanu. Glomeruli amathandiza kusefa zonyansa m'magazi anu ndikuziika mumkodzo.

Zizindikiro za glomerulonephritis zitha kuphatikiza:

  • Kutupa ndi kutupa chifukwa chosungira madzi, makamaka kumaso, mapazi, manja, kapena m'mimba
  • kuthamanga kwa magazi
  • mkodzo womwe ndi wa pinki kapena wamdima wakuda
  • mkodzo womwe ukuwoneka ngati thovu

Ngati mukuganiza kuti muli ndi glomerulonephritis mukamamwa Neulasta, uzani dokotala wanu. Amatha kuchepetsa mlingo wanu, womwe nthawi zambiri umachotsa glomerulonephritis. Koma ngati izi sizigwira ntchito, dokotala wanu mwina akuyimitsani kumwa Neulasta. Atha kukupemphani kuti muyesere mankhwala ena m'malo mwake.

Leukocytosis

Leukocytosis ndizovuta koma zowopsa kwambiri za Neulasta.

M'maphunziro azachipatala, leukocytosis idachitika mwa anthu ochepera 1% omwe adamwa mankhwalawa. Neulasta amafanizidwa ndi placebo, koma sizikudziwika ngati leukocytosis idachitika kangati mwa anthu omwe adatenga placebo. Palibe zovuta zokhudzana ndi leukocytosis zomwe zidanenedwa m'maphunziro awa.

Leukocytosis ndi mkhalidwe womwe mulingo wamagazi oyera otchedwa leukocytes ndiwokwera kuposa wabwinobwino. Izi nthawi zambiri chimakhala chizindikiro kuti thupi lanu likuyesera kulimbana ndi matenda. Komabe, leukocytosis ikhozanso kukhala chizindikiro cha khansa ya m'magazi (khansa yomwe imakhudza mafupa kapena magazi).

Zizindikiro za leukocytosis zitha kuphatikizira:

  • kutuluka magazi kapena kuphwanya
  • mavuto opuma monga kupuma
  • malungo

Chifukwa muli pachiwopsezo chachikulu chotenga kachilombo mukamamwa Neulasta, uzani dokotala nthawi yomweyo mukayamba kutentha thupi kapena zizindikilo zina za leukocytosis. Adzakuthandizani kudziwa chomwe chikuyambitsa komanso chithandizo choyenera kwa inu.

Nthata yotuluka

Nkhuku yotambasula ndi ntchentche yotupa sizinatchulidwe m'mayesero azachipatala a Neulasta. Komabe, izi zanenedwa mwa anthu omwe adatenga Neulasta kuyambira pomwe mankhwalawa adadza pamsika.

Ndulu ndi chiwalo chomwe chili kumtunda chakumanzere kwa mimba yako, pansi pa nthiti zako. Zimagwira ntchito kusefa magazi ndikulimbana ndi matenda.

Zizindikiro za nthenda yotupa imatha kuphatikiza:

  • chisokonezo
  • kumva kuda nkhawa kapena kusakhazikika
  • mutu wopepuka
  • nseru
  • kupweteka kumtunda chakumanzere kumimba
  • khungu lotumbululuka
  • kupweteka m'mapewa

Nthata yotumphuka ndi moyo wowopsa womwe umafunikira chithandizo chamankhwala mwachangu. Ngati mukumwa Neulasta ndipo mukumva kupweteka paphewa lanu lakumanzere kapena kumtunda chakumanzere chakumanzere, uzani dokotala nthawi yomweyo.

Malungo (osati zotsatira zoyipa)

Kutentha thupi si zotsatira zoyembekezera za kutenga Neulasta.

Kukulitsa malungo mukalandira chithandizo cha Neulasta kungatanthauze kuti muli ndi matenda. Malungo amathanso kukhala chizindikiro cha zovuta zoyipa koma zoyipa za Neulasta, monga pachimake kupuma kwa matenda (ARDS), aortitis, kapena leukocytosis. (Kuti mumve zambiri za ARDS ndi leukocytosis, onani magawo omwe ali pansipa.)

Mukakhala ndi malungo mukatenga Neulasta, uzani dokotala wanu nthawi yomweyo. Amatha kuthandiza kudziwa chomwe chikuyambitsa kutentha thupi kwanu komanso njira yabwino yochiritsira.

Mlingo wa Neulasta

Mlingo wa Neulasta yemwe dokotala akukulemberani udalira pazinthu zingapo. Izi zikuphatikiza:

  • mtundu ndi kuuma kwa chikhalidwe chomwe mukugwiritsa ntchito Neulasta kuchiza
  • zaka zanu
  • mawonekedwe a Neulasta omwe mumatenga
  • matenda ena omwe mungakhale nawo

Nthawi zambiri, dokotala wanu amakupangitsani muyeso wochepa. Kenako azisintha pakapita nthawi kuti akwaniritse zomwe zikukuyenerani. Dokotala wanu pomaliza adzakupatsani mlingo wochepa kwambiri womwe umafunikira.

Chidziwitso chotsatirachi chimalongosola miyezo yomwe amagwiritsidwa ntchito kwambiri kapena amalimbikitsidwa. Komabe, onetsetsani kuti mwatenga mlingo womwe dokotala akukulemberani. Dokotala wanu adzazindikira mlingo woyenera kuti mukwaniritse zosowa zanu.

Mitundu ya mankhwala ndi mphamvu

Neulasta imabwera m'njira ziwiri. Imodzi ndi jakisoni woyambira limodzi. Fomuyi imaperekedwa tsiku lotsatira mukalandira mankhwala a chemotherapy monga jakisoni wocheperako (jakisoni pansi pa khungu lanu).

Wopereka chithandizo chamankhwala amakupatsani jekeseni wa Neulasta, kapena mutha kudzipatsa jekeseni kunyumba mukaphunzitsidwa. Sirinjiyo imapezeka mwamphamvu imodzi: 6 mg / 0.6 mL.

Fomu yachiwiri imatchedwa Neulasta Onpro, yomwe ndi jakisoni wa thupi (OBI). Wopereka chithandizo chamankhwala azigwiritsa ntchito m'mimba mwanu kapena kumbuyo kwa tsiku lomwelo tsiku lomwe mulandila chemotherapy.

Neulasta Onpro amapereka mankhwalawa pafupifupi tsiku limodzi OBI atagwiritsidwa ntchito. Izi zikutanthauza kuti simuyenera kubwerera ku ofesi ya dokotala kuti mukalandire jakisoni. Neulasta Onpro amapezeka mwamphamvu imodzi: 6 mg / 0.6 mL.

Ndikofunika kuzindikira kuti Neulasta Onpro sagwiritsidwa ntchito pochiza matenda a radiation.

Mlingo wopewa matenda pa chemotherapy

Pofuna kupewa matenda pa chemotherapy, Neulasta amapatsidwa ngati kamodzi kamodzi pa chemotherapy. Mlingo umodzi wokha ndi jekeseni umodzi wokhala ndi sirinji kapena kugwiritsa ntchito Neulasta Onpro imodzi.

Musagwiritse ntchito Neulasta mwina masiku 14 kale kapena maola 24 mutalandira mankhwala a chemotherapy.

Mlingo wa matenda a radiation

Pochiza hematopoietic subsyndrome of acute radiation syndrome (matenda a radiation), Neulasta imaperekedwa ngati mitundu iwiri. Mudzawapatula sabata limodzi. Mlingo umodzi wokha ndi jakisoni umodzi wokhala ndi sirinji.

Mlingo wa ana

Neulasta imavomerezedwa kuthandiza kupewa matenda mwa ana omwe alandila chemotherapy. Mankhwalawa amavomerezedwa kuti agwiritsidwe ntchito kwa ana omwe ali ndi matenda a radiation. Palibe zoletsa zoyambira kugwiritsa ntchito Neulasta.

Pa miyezo ya Neulasta mwa ana omwe amalemera makilogalamu 99 (onani makilogalamu 45), onani magawo omwe ali pamwambapa.

Mlingo wa ana omwe amalemera makilogalamu ochepera 99 (45 kg) amatengera kulemera kwake. Dokotala wa mwana wanu adzazindikira kuti mlingo wa Neulasta ndi woyenera kwa mwana wanu.

Ndingatani ngati ndaphonya mlingo?

Mukaphonya kudzipatsa jekeseni wa Neulasta ndi jakisoni, itanani dokotala wanu mukazindikira izi. Amatha kukulangizani za momwe mungamwe mankhwala.

Ngati mwaphonya nthawi yokumana ndi jekeseni wa Neulasta, itanani ofesi ya dokotala. Ogwira ntchitoyo akhoza kukusinthirani nthawi ndi kusintha nthawi yochezera mtsogolo, ngati kuli kofunikira.

Ndikothekanso kuphonya mlingo mukamagwiritsa ntchito Neulasta Onpro. Izi ndichifukwa choti jakisoni wapathupi nthawi zina amatha kulephera kugwira ntchito kapena kutayikira. Izi zikachitika, itanani ofesi ya dokotala nthawi yomweyo. Ogwira ntchito akukonzekera nthawi yoti mudzabwerere jekeseni wa Neulasta kuti mulandire mlingo wanu wonse.

Pofuna kuthandizira kuti musaphonye mlingo, yesani kukhazikitsa chikumbutso pafoni yanu. Muthanso kulemba ndondomeko yanu yothandizira kalendala.

Kodi ndiyenera kugwiritsa ntchito mankhwalawa nthawi yayitali?

Neulasta amayenera kugwiritsidwa ntchito ngati chithandizo chanthawi yayitali, bola mukalandira chemotherapy. Ngati inu ndi adotolo mumazindikira kuti Neulasta ndiwotetezeka komanso yothandiza kwa inu, mungatenge nthawi yayitali.

Mafunso wamba pa Neulasta

Nawa mayankho pamafunso omwe amafunsidwa kawirikawiri za Neulasta.

Kodi Claritin angandithandizire kuthetsa mavuto a Neulasta?

Mwina. Neulasta imagwira ntchito poyambitsa chitetezo cha m'thupi lanu kuti apange maselo oyera ambiri.

Mapuloteni ena otchedwa histamines nawonso amatulutsidwa ndi njirayi. Sizikudziwika bwino chifukwa chake kutulutsa ma histamines kumabweretsa zovuta monga kupweteka kwa mafupa. Koma kafukufuku wasonyeza kuti histamine imakhudzidwa ndikutupa, komwe kumatha kupweteka.

Claritin ndi mankhwala a antihistamine. Zimagwira ntchito poletsa zochita za histamine. Pochita izi, Claritin atha kuthandiza kuchepetsa kupweteka kwa mafupa kwa anthu omwe amamwa Neulasta, koma kafukufuku wina amafunika.

Ngati mukumwa Neulasta ndikumva kupweteka kwa mafupa, lankhulani ndi dokotala wanu. Atha kuwunikiranso chithandizo chomwe chilipo ndikuthandizani kudziwa omwe ndi abwino kwa inu.

Kodi zotsatira za kuwombera kwa Neulasta zimatenga nthawi yayitali bwanji?

Sizikudziwika chifukwa palibe zambiri zokwanira pazomwe zotsatira zoyipa za kuwombera kwa Neulasta zidatha.

M'maphunziro azachipatala, anthu ena anena kupweteka kwa mafupa kapena kupweteka m'manja kapena miyendo atalandira Neulasta. Koma ochita kafukufuku sanalembe kutalika kwa zotsatirapo zake.

Kuti mumve zambiri pazotsatira zoyipa za Neulasta, chonde onani gawo la "Neulasta zoyipa" pamwambapa. Muthanso kufikira dokotala wanu.

Kodi Neulasta amakhala nthawi yayitali bwanji m'dongosolo lanu?

Nthawi imatha kusiyanasiyana. Kafukufuku wamankhwala awonetsa kuti kuchotsa Neulasta m'thupi kumakhudzidwa ndi kulemera kwanu komanso kuchuluka kwa ma neutrophil (mtundu wa khungu loyera) womwe uli m'magazi anu.

Mwambiri, mutalandira jekeseni umodzi, Neulasta amachotsedwa kwathunthu m'dongosolo lanu pasanathe masiku 14.

Ndikauluka, kodi ndiyenera kuuza achitetezo ku eyapoti kuti ndili ndi Neulasta Onpro?

Inde. Wopanga Neulasta ali ndi khadi lazidziwitso la Transportation Security Administration (TSA) lomwe mutha kusindikiza ndikuwapatsa achitetezo pa eyapoti. Dinani apa kuti mupeze khadi.

Komabe, tikulimbikitsidwa kuti mupewe kuyenda (kuphatikiza kuyendetsa) pazenera la maola 26 mpaka 29 mukalandira Neulasta Onpro. Chipangizocho chikugawa mankhwalawo mthupi lanu panthawiyi. Ndipo kuyenda kumatha kuwonjezera chiopsezo kuti Neulasta Onpro agwetsedwe m'thupi lanu.

Ngati muli ndi mafunso okhudza chithandizo chanu cha Neulasta mukamayenda, lankhulani ndi dokotala wanu.

Chifukwa chiyani ndiyenera kusunga Neulasta Onpro kutali ndi mafoni am'manja ndi zida zina zamagetsi?

Zizindikiro zochokera kuzida zamagetsizi zimatha kusokoneza Neulasta Onpro ndikulepheretsa kuti mupereke mlingo wanu.

Ndikulimbikitsidwa kuti musunge Neulasta Onpro osachepera mainchesi 4 pazipangizo zamagetsi, kuphatikiza mafoni ndi ma microwaves.

Ngati muli ndi mafunso okhudza kugwiritsa ntchito Neulasta Onpro, funsani dokotala wanu.

Kodi ndingataye bwanji Neulasta Onpro?

Mukalandira mlingo wathunthu wa Neulasta pogwiritsa ntchito Neulasta Onpro, muyenera kutaya chipangizocho pochiyika mu chidebe cha Sharps.

Wopanga Neulasta ali ndi Sharps Disposal Container Program kuti akuthandizeni kutaya Neulasta Onpro bwinobwino. Izi zimaperekedwa kwaulere popanda zina. Mutha kudina apa kuti mulembetse pulogalamuyi (onani gawo la "Injector Disposal Program"), kapena itanani 1-844-696-3852.

Neulasta amagwiritsa ntchito

Food and Drug Administration (FDA) imavomereza mankhwala akuchipatala monga Neulasta kuti athetse mavuto ena. Neulasta itha kugwiritsidwanso ntchito polemba zina pazinthu zina. Kugwiritsa ntchito mankhwala osokoneza bongo ndi pamene mankhwala omwe amavomerezedwa kuti athetse vuto limodzi amagwiritsidwa ntchito kuthana ndi vuto lina.

Neulasta yopewa matenda opatsirana pogwiritsa ntchito chemotherapy

Chemotherapy ndi mtundu wa chithandizo cha khansa chomwe chimagwiritsa ntchito mankhwala kupha magawo a khansa. Izi zimathandiza kupewa khansa kukula ndikufalikira.

Komabe, chemotherapy sichidziwikiratu kwa maselo a khansa. Chemotherapy imawononganso maselo ena ogawanika m'thupi, kuphatikiza maselo othandiza monga maselo oyera amwazi.

Neutropenia ndimagazi momwe ma neutrophil amakhala otsika. Ma neutrophils ndi mtundu wamaselo oyera amagazi omwe amateteza thupi lanu ku matenda. Ngati milingo yanu ya neutrophil ndiyotsika, thupi lanu silitha kulimbana bwino ndi mabakiteriya. Chifukwa chake kukhala ndi neutropenia kumawonjezera chiopsezo chotenga matenda.

Febrile neutropenia imachitika mukakhala ndi neutropenia ndikukhala ndi malungo, omwe amatha kukhala chizindikiro cha matenda. Ndipo kukhala ndi neutropenia kumatanthauza kuti simungalimbane ndi matenda monga mwa masiku onse. Chifukwa chake febrile neutropenia ndi vuto lalikulu lomwe dokotala akuyenera kukawona nthawi yomweyo.

Zomwe Neulasta amachita

Neulasta imagwiritsidwa ntchito kuthandizira kupewa matenda kwa anthu omwe ali ndi khansa ina omwe amalandira chemotherapy. Khansa zimatchedwa non-myeloid cancer, zomwe sizimakhudza mafupa (minofu yomwe ili mkati mwa mafupa omwe amapanga ma cell amwazi). Chitsanzo cha khansa yopanda myeloid ndi khansa ya m'mawere.

Neulasta imakuthandizani pakupanga ma neutrophil ambiri ndi maselo ena oyera amwazi. Izi zimathandiza kuti thupi lanu likhale lokonzekera bwino kulimbana ndi matenda, kuthandizira kupewa febrile neutropenia, ndikuchepetsa kutalika kwa neutropenia.

Kuchita bwino

M'maphunziro azachipatala, Neulasta adawonetsedwa kuti amachepetsa chiopsezo cha febrile neutropenia komanso kuti matendawo amatenga nthawi yayitali bwanji kwa anthu omwe amakula.

Kafukufuku wina anayerekezera Neulasta ndi filgrastim (Neupogen), yomwe ndi mankhwala ena omwe amatsimikiziridwa kuti amathandizira kupewa ndikuchiza febrile neutropenia. Ofufuzawo amafuna kudziwa ngati Neulasta inali yothandiza ngati filgrastim pakufupikitsa kutalika kwa febrile neutropenia.

Pakafukufukuyu, anthu amalandila chemotherapy regimen (dongosolo lamankhwala) lopangidwa ndi doxorubicin ndi docetaxel masiku onse 21. Mitundu yofananira yolumikizidwa ndi neutropenia yayikulu yomwe imachitika nthawi zonse.

Vutoli limakhala pafupifupi masiku 5 mpaka 7 pafupifupi, ndipo pafupifupi 30% mpaka 40% ya anthu adayamba febrile neutropenia.

Anthuwo adapatsidwa mwayi wolandila Neulasta kapena filgrastim. Ofufuzawo adapeza kuti Neulasta inali yofananira ndi filgrastim.

Anthu omwe adalandira Neulasta ndipo adayamba kukhala ndi neutropenia anali ndi vuto la masiku 1.8. Anthu omwe adalandira filgrastim ndipo adayamba kukhala ndi neutropenia yayikulu amakhala ndi vuto la masiku 1.7.

Kafukufuku wachiwiri wokhala ndi mawonekedwe ofanana adapezanso zotsatira zofananira. Anthu omwe adalandira Neulasta ndipo adayamba kukhala ndi neutropenia anali ndi vuto la masiku 1.7. Izi zimafaniziridwa ndi pafupifupi masiku 1.6 mwa anthu omwe adalandira filgrastim.

Neulasta wa matenda a radiation

Neulasta imavomerezedwanso ndi FDA kuti ichiritse matenda a radiation. Vutoli limatha kutchulidwanso kuti radiation radiation kapena poyizoni wama radiation.

Mtundu wa matenda a radiation omwe Neulasta amagwiritsidwa ntchito amatchedwa hematopoietic subsyndrome. Kuchuluka kwa ma radiation omwe amayambitsa matendawa amadziwika kuti myelosuppressive, kutanthauza kuti amatsogolera mafupa anu kupanga ma cell ochepa amagazi.

Matenda a radiation amachitika munthu atakhala ndi radiation yambiri kwakanthawi kochepa (makamaka mphindi zochepa). Kuchuluka kwa ma radiation kumatha kupha ma cell amthupi mwanu. Matenda a radiation amatha kupha ngati kutulutsa kwa radiation kuli kokwanira.

Pazifukwa zamakhalidwe, ofufuza sanathe kuyesa kuthekera kwa Neulasta kuchiza matenda a radiation mwa anthu. M'malo mwake, mankhwalawa adavomerezedwa kuthana ndi matenda a radiation potengera maphunziro a nyama, kuwonjezera pa zomwe zatchulidwa mu "Neulasta yopewa matenda panthawi yamankhwala" gawo lomwe lili pamwambapa.

Zindikirani: Neulasta Onpro (jekeseni wa thupi wa Neulasta) sayenera kugwiritsidwa ntchito pochiza matenda a radiation.

Ntchito zosagwiritsidwa ntchito pa Neulasta

Kuphatikiza pazomwe zatchulidwa pamwambapa, Neulasta itha kugwiritsidwa ntchito polemba zina nthawi zina. Kugwiritsa ntchito mankhwala osokoneza bongo ndi pamene mankhwala omwe amavomerezedwa kuti agwiritsidwe ntchito kamodzi amagwiritsidwa ntchito mosiyana ndi omwe savomerezedwa.

Pambuyo pa hematopoietic cell transplants

Neulasta sivomerezedwa ndi FDA kuti igwiritsidwe ntchito pambuyo pa hematopoietic cell transplant (HCT). Komabe, mankhwalawa atha kugwiritsidwa ntchito ngati chizindikiro pa izi.

HCT ndi njira yomwe imachitika mutalandira mankhwala a chemotherapy. Chemotherapy ikagwiritsidwa ntchito kupha ma cell a khansa, maselo am'maso amaikidwa kwa inu nthawi ya HCT. Izi zachitika chifukwa chemotherapy sikuti imangowononga maselo a khansa. Ikhozanso kupha ma stem omwe amapangidwa ndi mafupa anu.

Maselo otchedwa stem cells nthawi zambiri amakhala maselo othandiza magazi kuundana (maselo a magazi amene amathandiza magazi kuundana), maselo ofiira, ndi maselo oyera a magazi, zomwe zonse ndi zofunika kuti mukhale ndi moyo.

HCT ikaperekedwa kwa anthu omwe ali ndi khansa yamagazi, matenda amatha. Izi ndichifukwa choti ma cell atsopanowa sagwira ntchito atangomaliza kumuika.

Kugwiritsa ntchito Neulasta pambuyo pa HCT kumathandiza thupi lanu kupanga maselo oyera oyera, kuphatikiza ma neutrophil. Ma neutrophil abwino amathandiza thupi lanu kuthana ndi matenda bwino.

Kuchita bwino

Ngakhale Neulasta sivomerezedwa ndi FDA kuti igwiritsidwe ntchito pambuyo pa HCT, maphunziro azachipatala awonetsa kuti mankhwalawa ndi othandiza pakugwiritsa ntchito izi.

Kafukufuku wina anayerekezera Neulasta ndi mankhwala ofanana nawo, filgrastim (Neupogen), omwe amavomerezedwa ndi FDA kuti agwiritsidwe ntchito pambuyo pa HCT. Neulasta amaperekedwa ngati jekeseni umodzi wokha, pomwe filgrastim imaperekedwa ngati jakisoni angapo masiku angapo.

Phunziroli, anthu 14 omwe alibe Hodgkin lymphoma, angapo myeloma, kapena amyloidosis adalandira Neulasta atakhala ndi HCT.

Ofufuzawo anayerekezera zotsatira za anthuwa ndi zotsatira za anthu omwe adalandira filgrastim m'mbuyomu. Izi zikutanthauza kuti panalibe gulu la placebo (chithandizo chopanda mankhwala osokoneza bongo).

Ofufuzawa adapeza kuti zidatenga pafupifupi masiku 11 kuti ma neutrophil abwerere kumtunda mwa anthu omwe adalandira Neulasta. Poyerekeza, zimatenga masiku pafupifupi 14 kwa anthu omwe adatenga filgrastim m'mbuyomu.

Ngati muli ndi mafunso okhudza kutenga Neulasta pambuyo pa HCT, lankhulani ndi dokotala wanu.

Neulasta ndi ana

Neulasta imavomerezedwa kuthandiza kupewa matenda mwa ana omwe alandila chemotherapy. Mankhwalawa amavomerezedwa kuti agwiritsidwe ntchito kwa ana omwe ali ndi matenda a radiation. Palibe zoletsa zoyambira kugwiritsa ntchito Neulasta.

Kugwiritsa ntchito Neulasta ndi mankhwala ena

Neulasta amagwiritsidwa ntchito ndi mankhwala ena. Izi ndichifukwa choti Neulasta ndi gawo limodzi lokha la dongosolo la chithandizo cha khansa.

Neulasta amagwiritsidwa ntchito kwambiri ndi chemotherapy chifukwa Neulasta imathandizira kupewa kapena kuchiza zovuta zina za chemotherapy.

Mankhwala omwe amagwiritsidwa ntchito kwambiri monga:

  • alireza
  • carboplatin
  • cyclophosphamide
  • docetaxel (Taxotere)
  • doxorubicin (Doxil)
  • miyala yamtengo wapatali (Gemzar)
  • chiwoo

Kumbukirani kuti iyi si mndandanda wonse wa mankhwala a chemotherapy. Lankhulani ndi dokotala wanu ngati muli ndi mafunso okhudzana ndi mankhwala a chemotherapy komanso ngati Neulasta angakupindulitseni.

Njira zina ku Neulasta

Mankhwala ena alipo omwe angathetse vuto lanu. Zina zitha kukuyenererani kuposa ena. Ngati mukufuna kupeza njira ina ya Neulasta, lankhulani ndi dokotala wanu. Amatha kukuwuzani zamankhwala ena omwe atha kukuthandizani.

Zindikirani: Mankhwala ena omwe atchulidwa pansipa sanagwiritsidwe ntchito polemba izi. Kugwiritsa ntchito mankhwala osokoneza bongo ndi pamene mankhwala omwe amavomerezedwa kuti athetse vuto limodzi amagwiritsidwa ntchito kuthana ndi vuto lina.

Njira zina zopewera matenda pa chemotherapy

Zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito popewa matenda pa chemotherapy ndi awa:

  • zojambulajambula (Granix)
  • pegfilgrastim (Fulphila)
  • sargramostim (Leukine)
  • zojambulazo (Neupogen)
  • firimu-aafi (Nivestym)
  • pegfilgrastim-cbqv (Udenyca)
  • zithunzi-sndz (Zarxio)
  • Lufuno Dagada - Mishumo Ya Tshilidzi

Njira zina zothandizira matenda a radiation

Zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito pochiza matenda a radiation ndi awa:

  • zojambula-grgrim (Granix)
  • ayodini wa potaziyamu
  • Prussian buluu
  • pegfilgrastim (Fulphila)
  • zojambulazo (Neupogen)
  • firimu-aafi (Nivestym)
  • pegfilgrastim-cbqv (Udenyca)
  • zithunzi-sndz (Zarxio)
  • Lufuno Dagada - Mishumo Ya Tshilidzi

Neulasta vs. Granix

Mutha kudabwa momwe Neulasta amafanizira ndi mankhwala ena omwe amaperekedwa kuti agwiritse ntchito chimodzimodzi. Apa tikuwona momwe Neulasta ndi Granix alili ofanana komanso osiyana.

Zosakaniza

Neulasta lili yogwira mankhwala pegfilgrastim. Granix lili yogwira mankhwala tbo-filgrastim.

Pegfilgrastim ndi tbo-filgrastim onse ali mgulu la mankhwala otchedwa granulocyte-colony zinthu zolimbikitsa (G-CSFs). Kalasi ya mankhwala ndi gulu la mankhwala omwe amagwiranso ntchito chimodzimodzi.

G-CSF ndi mankhwala omwe amayambitsa ma neutrophil (mtundu wamaselo oyera amwazi) kukula m'mafupa anu. Mafupa ndi mafupa mkati mwa mafupa omwe amapanga maselo amwazi. G-CSFs ndimakina opangidwa ndi anthu a G-CSF hormone yomwe thupi lanu limapanga mwachilengedwe.

Ntchito

Neulasta ndi Granix onse amavomerezedwa ndi Food and Drug Administration (FDA) kuti achepetse chiopsezo chotenga kachilombo kaamba ka matenda omwe amatchedwa febrile neutropenia mwa anthu omwe ali ndi khansa yopanda myeloid. * Kuti mugwiritse ntchito mankhwalawa, muyenera kukhala mukumwa mankhwala a khansa omwe angayambitse febrile neutropenia.

Neulasta imavomerezedwanso ndi FDA kuti ithetse matenda a radiation. * Mtundu wamatenda a radiation omwe Neulasta amagwiritsidwa ntchito amatchedwa hematopoietic subsyndrome.

Mafomu azamankhwala ndi makonzedwe

Nazi zambiri zamitundu ya Neulasta ndi Granix ndi momwe amaperekedwera.

Mafomu a Neulasta

Neulasta imabwera m'njira ziwiri. Imodzi ndi jakisoni woyambira limodzi. Fomuyi imaperekedwa tsiku lotsatira mukalandira mankhwala a chemotherapy monga jakisoni wocheperako (jakisoni pansi pa khungu lanu).

Wopereka chithandizo chamankhwala amakupatsani jekeseni wa Neulasta, kapena mutha kudzipatsa jekeseni kunyumba mukaphunzitsidwa.

Fomu yachiwiri imatchedwa Neulasta Onpro, yomwe ndi jakisoni wa thupi (OBI). Wopereka chithandizo chamankhwala azigwiritsa ntchito m'mimba mwanu kapena kumbuyo kwa tsiku lomwelo tsiku lomwe mulandila chemotherapy.

Neulasta Onpro amapereka mankhwalawa pafupifupi tsiku limodzi OBI atagwiritsidwa ntchito. Izi zikutanthauza kuti simuyenera kubwerera ku ofesi ya dokotala kuti mukalandire jakisoni.

Zindikirani: Neulasta Onpro sagwiritsidwa ntchito pochiza matenda a radiation.

Mafomu a Granix

Granix imabweranso m'njira ziwiri: jakisoni woyambira limodzi ndi botolo limodzi la madzi. Mitundu yonseyi imatha kuperekedwa ndi wothandizira zaumoyo ngati jakisoni mobisa, molunjika pansi pa khungu lanu. Koma ndi maphunziro ena, mutha kudzipatsa jakisoni kunyumba.

Mlingo pafupipafupi

Kusiyana kwakukulu pakati pa Neulasta ndi Granix ndikuti mankhwala amaperekedwa kangati kuti achepetse kutenga kachilombo ka chemotherapy.

Neulasta imaperekedwa kamodzi kokha panthawi iliyonse ya chemotherapy. Granix, mbali inayo, imaperekedwa tsiku lililonse mpaka kuchuluka kwa ma neutrophil m'magazi anu kubwerera mwakale.

Zotsatira zoyipa ndi zoopsa

Neulasta ndi Granix onse amagwiritsidwa ntchito kuthandiza kupewa matenda pa chemotherapy. Chifukwa chake, mankhwalawa amatha kuyambitsa zovuta zina, koma enanso osiyanasiyana. M'munsimu muli zitsanzo za zotsatirazi.

Zotsatira zoyipa

Mndandandawu muli zitsanzo za zovuta zoyipa zomwe zitha kuchitika ndi Neulasta, ndi Granix, kapena ndi mankhwala onse (akamwedwa payekhapayekha).

  • Zitha kuchitika ndi Neulasta:
    • zotsatira zapadera zochepa
  • Zitha kuchitika ndi Granix:
    • mutu
    • kupweteka kwa minofu
    • kusanza
  • Zitha kuchitika ndi onse Neulasta ndi Granix:
    • kupweteka kwa mafupa
    • kupweteka m'manja kapena miyendo yanu

Zotsatira zoyipa

Mndandandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Neulasta, ndi Granix, kapena ndi mankhwala onse (akamwedwa payekhapayekha).

  • Zitha kuchitika ndi Neulasta:
    • zotsatira zapadera zochepa
  • Zitha kuchitika ndi Granix:
    • cutaneous vasculitis (kutupa kwa mitsempha ya khungu)
    • thrombocytopenia (magawo otsika kwambiri)
    • matenda a zenga (gulu la zovuta zomwe zimakhudza maselo ofiira, makamaka hemoglobin)
  • Zitha kuchitika ndi onse Neulasta ndi Granix:
    • thupi lawo siligwirizana
    • leukocytosis (kuchuluka kwa maselo oyera amwazi)
    • nthata yotumphuka (kutsegula kwa chiwalo chotchedwa ndulu)
    • Matenda ovuta kupuma (mtundu wamapapu)
    • glomerulonephritis (gulu la impso)
    • capillary leak syndrome (momwe mitsempha yaying'ono yamagazi imatulukira)
    • aortitis (kutupa kwa aorta, mitsempha yayikulu yamtima)

Kuchita bwino

Ntchito zokhazokha zomwe Neulasta ndi Granix amavomereza ndikuchepetsa chiopsezo chotenga matenda chifukwa cha matenda omwe amatchedwa febrile neutropenia mwa anthu omwe ali ndi khansa yomwe siili ya myeloid.

Kafukufuku wosiyanasiyana wa mankhwala awiriwa adafanizidwa pakuwunikanso kwakukulu kwamaphunziro omwe amatchedwa kuwunika kwadongosolo. Ochita kafukufuku adayang'ana zidziwitso kuchokera m'maphunziro 18.

Anthu anali atalandira pegfilgrastim (mankhwala omwe amagwiritsidwa ntchito ku Neulasta), filgrastim, kapena mankhwala omwewo, kuphatikiza Granix. Gulu la pegfilgrastim silimatha kukhala ndi febrile neutropenia ndipo silingafune kukhala kuchipatala chifukwa cha febrile neutropenia. Izi zimafaniziridwa ndi magulu ena azamankhwala.

Mtengo

Neulasta ndi Granix onse ndi mankhwala osokoneza bongo.

Neulasta ili ndi mitundu itatu ya biosimilar: Fulphila, Udenyca, ndi Ziextenzo.

Granix sadziwika kuti ndi biosimilar, malinga ndi FDA.

Biosimilar ndi mankhwala omwe amafanana ndi mankhwala omwe amadziwika ndi dzina. Komano, mankhwala achibadwa, ndiwo mankhwala enieni amene ali mu dzina la mankhwala.

Biosimilars amachokera ku mankhwala a biologic, omwe amapangidwa kuchokera kuzinthu zamoyo. Zodzoladzola zimadalira mankhwala omwe amapangidwa kuchokera ku mankhwala. Ma biosimilars ndi generic amakhalanso otsika mtengo poyerekeza ndi mankhwala omwe amadziwika nawo.

Malinga ndi kuyerekezera kwa GoodRx.com, mitengo ya Neulasta ndi Granix idzasiyana kutengera mulingo woyenera. Mtengo weniweni womwe mudzalipire mankhwalawa umadalira dongosolo lanu la inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Neulasta vs.Fulphila

Monga Granix (yofotokozedwa pamwambapa), mankhwala a Fulphila adagwiritsa ntchito ofanana ndi a Neulasta. Nayi kufananiza momwe Neulasta ndi Fulphila alili ofanana komanso osiyana.

Zosakaniza

Neulasta ndi Fulphila ali ndi mankhwala omwewo, pegfilgrastim.

Mwaukadaulo, Fulphila ili ndi chinthu chogwira ntchito pegfilgrastim-jmdb. Izi ndichifukwa choti Fulphila ndi mtundu wa mankhwala omwe amadziwika kuti biosimilar. Biosimilar ndi mankhwala omwe amafanana ndi mankhwala omwe amadziwika ndi dzina. Biosimilars amachokera ku mankhwala a biologic, omwe amapangidwa kuchokera kuzinthu zamoyo.

Pachifukwa ichi, Neulasta ndiye mankhwala a biologic, ndipo Fulphila ndiye biosimilar yake. Pegfilgrastim ndi pegfilgrastim-jmdb onse amagwira ntchito chimodzimodzi.

Pegfilgrastim ndi m'gulu la mankhwala otchedwa granulocyte-colony factor stimulating factor (G-CSFs). Gulu la mankhwala ndi gulu la mankhwala omwe amagwiranso ntchito chimodzimodzi.

G-CSF ndi mankhwala omwe amayambitsa ma neutrophil (mtundu wamaselo oyera amwazi) kukula m'mafupa anu. Mafupa ndi mafupa omwe ali mkati mwa mafupa omwe amapanga maselo amwazi. Ndipo ma G-CSF ndi makope opangidwa ndi anthu a G-CSF hormone yomwe thupi lanu limapanga mwachilengedwe.

Ntchito

Neulasta ndi Fulphila onse amavomerezedwa ndi Food and Drug Administration (FDA) kuti achepetse chiopsezo chotenga kachilombo kaamba ka matenda omwe amatchedwa febrile neutropenia mwa anthu omwe ali ndi khansa yopanda myeloid. * Kuti mugwiritse ntchito mankhwalawa, muyenera kukhala mukumwa mankhwala a khansa omwe angayambitse febrile neutropenia.

Neulasta imavomerezedwanso ndi FDA kuti ithetse matenda a radiation. * Mtundu wamatenda a radiation omwe Neulasta amagwiritsidwa ntchito amatchedwa hematopoietic subsyndrome.

Fulphila sakuvomerezedwa kuti athandize kusuntha maselo amwazi kuchokera m'mafupa kupita m'mwazi chifukwa chakuika ma hematopoietic cell (HCT).

Mafomu azamankhwala ndi makonzedwe

Neulasta ndi Fulphila onse amabwera ngati sirinji imodzi. Fomuyi imaperekedwa tsiku lotsatira mukalandira mankhwala a chemotherapy monga jakisoni wocheperako (jakisoni pansi pa khungu lanu).

Wopereka chithandizo chamankhwala amakupatsani jekeseni wa Neulasta, kapena mutha kudzipatsa jekeseni kunyumba mukaphunzitsidwa.

Neulasta imabweranso m'njira ina yotchedwa Neulasta Onpro, yomwe ndi jakisoni wapathupi (OBI). Wopereka chithandizo chamankhwala azigwiritsa ntchito m'mimba mwanu kapena kumbuyo kwa tsiku lomwelo tsiku lomwe mulandila chemotherapy.

Neulasta Onpro amapereka mankhwalawa pafupifupi tsiku limodzi OBI atagwiritsidwa ntchito. Izi zikutanthauza kuti simuyenera kubwerera ku ofesi ya dokotala kuti mukalandire jakisoni.

Zindikirani: Neulasta Onpro sagwiritsidwa ntchito pochiza matenda a radiation.

Zotsatira zoyipa ndi zoopsa

Neulasta ndi Fulphila onse ali ndi pegfilgrastim. Chifukwa chake, mankhwalawa amatha kuyambitsa zovuta zina. M'munsimu muli zitsanzo za zotsatirazi.

Zotsatira zoyipa

Mndandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Neulasta ndi Fulphila (akatengedwa payekha):

  • kupweteka kwa mafupa
  • kupweteka m'manja kapena miyendo yanu

Zotsatira zoyipa

Mndandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Neulasta ndi Fulphila (akatengedwa payekha):

  • thupi lawo siligwirizana
  • Matenda ovuta kupuma (mtundu wamapapu)
  • aortitis (kutupa kwa aorta, mitsempha yayikulu yamtima)
  • capillary leak syndrome (momwe mitsempha yaying'ono yamagazi imatulukira)
  • glomerulonephritis (gulu la impso)
  • leukocytosis (kuchuluka kwa maselo oyera amwazi)
  • nthata yotumphuka (kutsegula kwa chiwalo chotchedwa ndulu)

Kuchita bwino

Ntchito zokhazokha zomwe Neulasta ndi Fulphila amavomerezedwa ndikuchepetsa chiopsezo chotenga matenda chifukwa cha matenda omwe amatchedwa febrile neutropenia mwa anthu omwe ali ndi khansa yomwe siili ya myeloid.

Mankhwalawa sanayerekezeredwe mwachindunji m'maphunziro azachipatala, koma kafukufuku wapeza kuti Neulasta ndi Fulphila onse ali othandiza pochepetsa chiopsezo chotenga matenda chifukwa cha matenda omwe amatchedwa febrile neutropenia mwa anthu omwe ali ndi khansa yopanda myeloid.

Mtengo

Malinga ndi kuyerekezera kwa GoodRx.com, Neulasta amawononga ndalama zambiri kuposa Fulphila. Mtengo weniweni womwe mudzalipire mankhwalawa umadalira dongosolo lanu la inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Zachilengedwe kapena biosimilars

Mankhwala ambiri omwe amapangidwa ndi mankhwala amakhala ndi mitundu ina. Mankhwala achibadwa ndi mtundu weniweni wa mankhwala omwe ali ndi dzina lodziwika. Nthawi zambiri zimakhala zotsika poyerekeza ndi mtundu wamaina.

Komabe, Neulasta ndi Fulphila onse ndi mankhwala amtundu wa biologic, omwe amapangidwa kuchokera kuzinthu zamoyo. M'malo mochita kupanga, mankhwala a biologic amakhala ndi biosimilars. Biosimilar ndi mankhwala omwe amafanana ndi mankhwala a biologic.

Monga ma generic, ma biosimilars nthawi zambiri amawononga ndalama zochepa kuposa biologic yomwe amadziwika nayo.

Neulasta ili ndi mitundu itatu ya biosimilar: Fulphila, Udenyca, ndi Ziextenzo. Chifukwa chake a Living ndi biosimilar a Neulasta. Ngati mungafune kudziwa zambiri zama Neulasta a biosimilar, kuphatikiza a Fulphila, lankhulani ndi dokotala kapena wamankhwala.

Momwe Neulasta amagwirira ntchito

Nazi zina zokhudza zomwe Neulasta amachitira ndi momwe mankhwalawa amagwirira ntchito.

Febrile neutropenia

Neulasta imathandiza kuchepetsa chiopsezo chotenga matenda chifukwa cha matenda omwe amatchedwa febrile neutropenia mwa anthu omwe ali ndi khansa yomwe siili ya myeloid.

Neutropenia ndimagazi momwe ma neutrophil amakhala otsika. Ma neutrophils ndi mtundu wamaselo oyera amagazi omwe amateteza thupi lanu ku matenda. Ngati milingo yanu ya neutrophil ndiyotsika, thupi lanu silitha kulimbana bwino ndi mabakiteriya. Chifukwa chake kukhala ndi neutropenia kumawonjezera chiopsezo chotenga matenda.

Febrile neutropenia imachitika mukakhala ndi neutropenia ndikukhala ndi malungo, omwe amatha kukhala chizindikiro cha matenda. Ndipo kukhala ndi neutropenia kumatanthauza kuti simungalimbane ndi matenda monga mwa masiku onse. Chifukwa chake febrile neutropenia ndi vuto lalikulu lomwe dokotala akuyenera kukawona nthawi yomweyo.

Khansa yopanda myeloid ndi khansa yomwe sikukhudza mafupa, yomwe ndi minofu yomwe ili mkati mwa mafupa omwe amapanga ma cell amwazi. Chitsanzo cha khansa yopanda myeloid ndi khansa ya m'mawere.

Matenda a radiation

Neulasta imagwiritsidwanso ntchito pochiza matenda a radiation, zomwe zimachitika mukakumana ndi radiation yambiri. Ikhoza kutchulidwanso kuti matenda oopsa a radiation.

Mtundu wa matenda a radiation omwe Neulasta amagwiritsidwa ntchito amatchedwa hematopoietic subsyndrome. Kuchuluka kwa ma radiation omwe amayambitsa matendawa amadziwika kuti myelosuppressive, kutanthauza kuti amatsogolera mafupa anu kupanga ma cell ochepa amagazi.

Momwe Neulasta amagwirira ntchito

Chochititsa chidwi cha Granulocyte-colony factor (G-CSF) ndi timadzi timene timayambitsa ma neutrophils kuti akule m'mafupa.

Mankhwala omwe amagwiritsidwa ntchito ku Neulasta, pegfilgrastim, ndi mtundu wopangidwa ndi anthu wamtundu wa G-CSF womwe thupi lanu limapanga mwachilengedwe. Pegfilgrastim imagwiranso chimodzimodzi ndi G-CSF yachilengedwe.

Neulasta imakuthandizani pakupanga ma neutrophil ambiri ndi maselo ena oyera amwazi. Izi zimathandiza kuti thupi lanu likhale lokonzekera bwino kulimbana ndi matenda, kupewa febrile neutropenia, ndikuchepetsa kutalika kwa neutropenia.

Chifukwa cha hematopoietic subsyndrome chifukwa cha matenda a radiation, Neulasta imathandizira thupi lanu m'malo mwa maselo oyera amwazi omwe adawonongeka m'mafupa ndikuwonetsedwa ndi radiation.

Zimatenga nthawi yayitali bwanji kuti zigwire ntchito?

Neulasta imayamba kugwira ntchito itangolowa m'thupi lanu. Komabe, kafukufuku wamankhwala akuwonetsa kuti zingatenge masabata 1 kapena 2 kuti milingo ya neutrophil ibwerere mwakale mukalandira mankhwala a Neulasta kutsatira chemotherapy.

Neulasta ndi mowa

Pakadali pano, palibe kulumikizana komwe kumadziwika pakati pa Neulasta ndi mowa.

Komabe, mowa umatha kusokoneza mankhwala ena a chemotherapy kapena kukulitsa zovuta zake.

Lankhulani ndi dokotala wanu ngati zakumwa zoledzeretsa zili bwino kuti muzimwa mukamamwa mankhwala a chemotherapy. (Neulasta amaperekedwa pambuyo pa mankhwala a chemotherapy.)

Kuyanjana kwa Neulasta

Palibe kuyanjana kulikonse komwe kumadziwika pakati pa Neulasta ndi mankhwala ena, zitsamba ndi zowonjezera, ndi zakudya.

Neulasta ndi mankhwala ena

Sizikudziwika ngati pali zomwe zimachitika pakati pa Neulasta ndi mankhwala ena. Izi ndichifukwa choti palibe maphunziro omwe adachitidwa kuti azindikire kuyanjana kwa mankhwala. Kutengera momwe mankhwalawa amagwirira ntchito, kuyanjana ndi mankhwala ena sizokayikitsa.

Ngati muli ndi mafunso okhudzana ndi mankhwala omwe angakukhudzeni, funsani dokotala kapena wamankhwala.

Neulasta ndi zitsamba ndi zowonjezera

Palibe zitsamba zilizonse kapena zowonjezera zomwe zanenedwa kuti zimalumikizana ndi Neulasta. Komabe, muyenera kuonana ndi dokotala kapena wamankhwala musanagwiritse ntchito mankhwalawa mukamamwa Neulasta.

Neulasta ndi zakudya

Palibe zakudya zilizonse zomwe zanenedwa kuti zimalumikizana ndi Neulasta. Ngati muli ndi mafunso okhudzana ndi kudya zakudya zina mukamamwa Neulasta, lankhulani ndi dokotala wanu.

Mtengo wa Neulasta

Monga mankhwala onse, mtengo wa Neulasta umasiyana.

Mtengo weniweni womwe mudzalipira uzidalira dongosolo la inshuwaransi yanu, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Ndikofunika kuzindikira kuti muyenera kupita ku Neulasta ku pharmacy yapadera. Mankhwala amtunduwu amaloledwa kunyamula mankhwala apadera. Awa ndi mankhwala omwe angakhale okwera mtengo kapena omwe angafunike thandizo kuchokera kwa akatswiri azaumoyo kuti agwiritsidwe ntchito mosamala komanso moyenera.

Ndondomeko yanu ya inshuwaransi ingafune kuti mupeze chilolezo musanavomereze Neulasta. Izi zikutanthauza kuti dokotala wanu ndi kampani ya inshuwaransi adzafunika kuti adziwitse za mankhwala anu kampani ya inshuwaransi isanakonze mankhwalawo. Kampani ya inshuwaransi iunikanso pempholi ndikudziwitsani inu ndi dokotala ngati pulani yanu ikwaniritsa Neulasta.

Ngati simukudziwa ngati mukufuna kupeza chilolezo cha Neulasta, lemberani dongosolo la inshuwaransi yanu.

Thandizo lazachuma komanso inshuwaransi

Ngati mukufuna thandizo lazachuma kuti mulipire Neulasta, kapena ngati mukufuna thandizo kuti mumvetsetse inshuwaransi yanu, thandizo lilipo.

Amgen Inc., wopanga Neulasta, amapereka mapulogalamu otchedwa Amgen FIRST STEP ndi Amgen Assist 360. Kuti mumve zambiri komanso kuti mudziwe ngati mukuyenera kuthandizidwa, itanani 888-657-8371 kapena pitani patsamba lawebusayiti.

Mtundu wa biosimilar

Neulasta imapezeka m'mitundu itatu ya biosimilar: Fulphila, Udenyca, ndi Ziextenzo.

Biosimilar ndi mankhwala omwe amafanana ndi mankhwala omwe amadziwika ndi dzina. Komano, mankhwala achibadwa, ndiwo mankhwala enieni amene ali mu dzina la mankhwala.

Biosimilars amachokera ku mankhwala a biologic, omwe amapangidwa kuchokera kuzinthu zamoyo. Zodzikongoletsera zimachokera ku mankhwala wamba omwe amapangidwa ndi mankhwala. Ma biosimilars ndi generic amakhalanso otsika mtengo poyerekeza ndi mankhwala omwe amadziwika nawo.

Kuti mudziwe momwe mitengo ya Fulphila, Udenyca, ndi Ziextenzo ikufananirana ndi mtengo wa Neulasta, pitani ku GoodRx.com. Apanso, mtengo womwe mumapeza pa GoodRx.com ndiomwe mungalipire popanda inshuwaransi. Mtengo weniweni womwe mudzalipira umadalira pulani ya inshuwaransi yanu, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Ngati dokotala wanu wakulemberani Neulasta ndipo mukufuna kugwiritsa ntchito Fulphila, Udenyca, ndi Ziextenzo m'malo mwake, lankhulani ndi dokotala wanu. Amatha kukhala ndi zokonda zamtundu wina kapena zinazo. Muyeneranso kuwunika inshuwaransi yanu, chifukwa imangokhudza chimodzi kapena chimzake.

Momwe mungatengere Neulasta

Muyenera kutenga Neulasta malinga ndi malangizo a dokotala kapena wothandizira zaumoyo.

Nthawi yoti mutenge

Neulasta imabwera m'njira ziwiri. Imodzi ndi jakisoni woyambira limodzi. Fomuyi imaperekedwa tsiku lotsatira mukalandira mankhwala a chemotherapy monga jakisoni wocheperako (jakisoni pansi pa khungu lanu). Wopereka chithandizo chamankhwala amakupatsani jekeseni wa Neulasta, kapena mutha kudzipatsa jekeseni kunyumba mukaphunzitsidwa.

Fomu yachiwiri amatchedwa Neulasta Onpro. Ndi jakisoni wapathupi (OBI) yemwe wothandizira zaumoyo adzagwiritsa ntchito m'mimba mwanu kapena kumbuyo kwa mkono wanu. Adzachita izi tsiku lomwelo mukalandira chemotherapy.

Kenako OBI idzakupatsani mlingo wanu wa Neulasta pafupifupi maola 27 mutamangiriridwa. Izi zikutanthauza kuti simuyenera kubwerera ku ofesi ya dokotala kuti mukalandire jakisoni.

Ndikofunika kuzindikira kuti Neulasta Onpro sagwiritsidwa ntchito pochiza matenda a radiation.

Neulasta ndi mimba

Sizikudziwika ngati Neulasta ndiwotheka kutenga nthawi yapakati.

Kafukufuku wachitika mu nyama zapakati zomwe zimapatsidwa filgrastim (mankhwala ofanana ndi Neulasta). Ochita kafukufuku sanapeze chiopsezo chowonjezeka cha kupunduka kwa kubadwa, kupita padera, kapena mavuto azaumoyo kwa mwana kapena mayi.

Komabe, maphunziro azinyama sikuwonetsa nthawi zonse zomwe zimachitika mwa anthu. Kafufuzidwe kena pa Neulasta ndi mimba ndikofunikira.

Ngati muli ndi pakati kapena mukukonzekera kutenga pakati, lankhulani ndi dokotala musanagwiritse ntchito Neulasta. Amatha kufotokoza za kuwopsa ndi phindu la mankhwalawo komanso njira zina zamankhwala.

Neulasta ndi kulera

Sizikudziwika ngati Neulasta ndiwotheka kutenga nthawi yapakati. (Onani gawo la "Neulasta ndi mimba" pamwambapa kuti mudziwe zambiri.) Ngati mukugonana ndipo inu kapena mnzanu mutha kutenga pakati, lankhulani ndi adotolo za zosowa zanu zakulera mukamagwiritsa ntchito Neulasta.

Neulasta ndi kuyamwitsa

Sizikudziwika ngati zili bwino kutenga Neulasta mukamayamwitsa.

Sitikudziwa ngati mankhwala omwe amagwiritsidwa ntchito ku Neulasta, pegfilgrastim, amapezeka mumkaka wa m'mawere.

Ngati mukumwa Neulasta ndikuganiza zoyamwitsa, lankhulani ndi dokotala wanu.

Zisamaliro za Neulasta

Mankhwalawa amabwera ndi zodzitetezera zingapo. Musanatenge Neulasta, kambiranani ndi dokotala za mbiri yanu. Neulasta sangakhale oyenera kwa inu ngati muli ndi matenda ena kapena zina zomwe zimakhudza thanzi lanu. Izi zikuphatikiza:

  • Khansa zina zamagazi. Ngati muli ndi khansa ya myeloid (khansa yomwe imakhudza mafupa), simuyenera kugwiritsa ntchito Neulasta. Mankhwalawa amatha kuyambitsa chotupa mwa anthu omwe ali ndi khansa yamagazi, makamaka khansa ya myeloid. Zotupa ndi unyinji wa minofu ya khansa. Funsani dokotala wanu za mankhwala ena omwe angakhale abwino kwa inu.
  • Matenda am'magazi. Kutenga Neulasta mukakhala ndi matenda a chikwakwa kungayambitse vuto la cellle, lomwe limatha kupha. (Matendawa amakhudza hemoglobin, yomwe imapezeka m'maselo ofiira ofiira.) Ngati muli ndi vuto la zenga, lankhulani ndi dokotala musanagwiritse ntchito Neulasta. Angakulimbikitseni njira zabwino zochiritsira.
  • Zozizira kwa akiliriki. Ngati simugwirizana ndi zomatira za akililiki, simuyenera kugwiritsa ntchito Neulasta Onpro, Neulasta injector wa thupi. Chipangizocho chimagwiritsa ntchito zomatira za akiliriki. Funsani dokotala wanu ngati jekeseni yoyendetsedwa ndi Neulasta ndi chisankho chabwino kwa inu.
  • Ziwengo kwa lalabala. Ngati muli ndi vuto la latex, simuyenera kugwiritsa ntchito majekeseni oyambira a Neulasta. Chipewa cha singano pamagirinji chimakhala ndi mphira wachilengedwe wochokera ku latex. Funsani dokotala ngati Neulasta Onpro pa thupi jakisoni ndibwino kwa inu.
  • Zowopsa ku Neulasta. Ngati muli ndi vuto la Neulasta kapena zina zake, musagwiritse ntchito mankhwalawa. Funsani dokotala wanu za njira zina zothandizira.
  • Mimba. Sizikudziwika ngati Neulasta ndiotetezeka kugwiritsa ntchito nthawi yapakati. Kuti mumve zambiri, onani gawo la "Neulasta ndi pakati" pamwambapa.
  • Kuyamwitsa. Sizikudziwika ngati zili bwino kutenga Neulasta mukamayamwitsa. Kuti mumve zambiri, onani gawo la "Neulasta ndi kuyamwitsa" pamwambapa.

Zindikirani: Kuti mumve zambiri paza zotsatira zoyipa za Neulasta, onani gawo la "Neulasta zoyipa" pamwambapa.

Neulasta bongo

Kugwiritsa ntchito mopitilira muyeso wa Neulasta kumatha kubweretsa zovuta zoyipa.

Zizindikiro zambiri za bongo

Zizindikiro za bongo zingaphatikizepo:

  • bloating ndi posungira madzimadzi
  • kupweteka kwa mafupa
  • kupuma movutikira
  • kuphulika kwa madzi (mapangidwe amadzi kuzungulira mapapo)

Zomwe muyenera kuchita mukamagwiritsa ntchito bongo

Ngati mukuganiza kuti mwamwa kwambiri mankhwalawa, itanani dokotala wanu. Muthanso kuyitanitsa American Association of Poison Control Center ku 800-222-1222 kapena kugwiritsa ntchito chida chawo pa intaneti. Koma ngati matenda anu akukulira, itanani 911 kapena pitani kuchipatala chapafupi pomwepo.

Kutha kwa Neulasta, kusunga, ndi kutaya

Mukapeza Neulasta kuchokera ku pharmacy, wamankhwala adzawonjezera tsiku lotha ntchito pa cholembedwera kapena katoni. Tsikuli limakhala chaka chimodzi kuyambira tsiku lomwe adapereka mankhwalawo.

Tsiku lothera ntchito limatsimikizira kuti mankhwalawa ndi othandiza panthawiyi. Maganizo apano a Food and Drug Administration (FDA) ndikupewa kugwiritsa ntchito mankhwala omwe atha ntchito.

Ngati mwagwiritsa ntchito mankhwala omwe sanadutse tsiku lomaliza, lankhulani ndi wamankhwala wanu ngati mungakwanitse kuugwiritsabe ntchito.

Yosungirako

Kutalika kwa nthawi yayitali kumadalira mankhwala, kuphatikiza momwe mungasungire mankhwalawo.

Muyenera kusunga ma syringe a Neulasta mufiriji (36 ° F mpaka 46 ° F / 2 ° C mpaka 8 ° C). Musamawumitse. Koma ngati ayamba kuzizira, siyani majekeseni asunthike mufiriji musanagwiritse ntchito. Ngati syringe yakhala yozizira nthawi yopitilira imodzi, itayeni.

Muyeneranso kutaya ma syringe aliwonse omwe mwasunga kutentha kwa nthawi yayitali kuposa maola 48. Pomaliza, osagwedeza masingano a Neulasta.

Kutaya

Nazi zambiri zamomwe mungatayire ma syringe a Neulasta omwe adakonzedweratu ndi Neulasta Onpro.

Neulasta adadzaza ma syringe

Mukangogwiritsa ntchito syringe yodzaza ndi Neulasta, ikani mu chidebe chovomerezedwa ndi FDA chololeza. Izi zimathandiza kupewa ena, kuphatikiza ana ndi ziweto, kumwa mankhwalawo mwangozi kapena kudzivulaza ndi singano.

Mutha kugula chidebe chakuthwa pa intaneti, kapena kufunsa dokotala, wamankhwala, kapena kampani ya inshuwaransi yazaumoyo komwe mungapeze.

Nkhaniyi imapereka malangizo othandiza pothana ndi mankhwala. Muthanso kufunsa wamankhwala wanu kuti mumve momwe mungatayire ma syringe anu.

Neulasta Onpro

Ngati mumagwiritsa ntchito Neulasta Onpro, pali malangizo apadera okhudza kutaya. Mukalandira mulingo wathunthu, muyenera kuyika Neulasta Onpro mu chidebe chakuthwa.

Wopanga Neulasta Onpro ali ndi Sharps Disposal Container Program yokuthandizani kutaya Neulasta Onpro. Izi zimaperekedwa kwaulere popanda zina. Mutha kudina apa kuti mulembetse pulogalamuyi, kapena itanani 844-696-3852.

Zambiri zamaluso za Neulasta

Zotsatirazi zimaperekedwa kwa azachipatala ndi ena othandizira azaumoyo.

Zisonyezero

Neulasta imawonetsedwa kuti imachepetsa chiopsezo cha matenda kwa odwala omwe ali ndi vuto losakhala la myeloid omwe amathandizidwa ndi mankhwala a myelosuppressive anti-cancer omwe amayambitsa febrile neutropenia.

Neulasta imavomerezedwanso kuti ipulumuke mwa anthu omwe ali ndi hematopoietic subsyndrome of acute radiation syndrome (radiation radiation).

Njira yogwirira ntchito

Chogwiritsira ntchito ku Neulasta, pegfilgrastim, ndichinthu chopangira cholimbikitsa. Amamangiriridwa ndi zolandirira pakhungu la maselo am'magazi am'magazi, zomwe zimayambitsa kuchuluka kwawo, kusiyanitsa, ndi kuyambitsa. Izi zimapangitsa kuti chiwerengero cha neutrophil (ANC) chiwonjezeke.

Pharmacokinetics ndi metabolism

Hafu ya moyo wa seramu wa Neulasta pambuyo poyendetsa pang'onopang'ono kuchokera pa 15 mpaka maola 80.

Odwala omwe ali ndi thupi lolemera kwambiri amakhala ndi mwayi wopezeka kwambiri ku Neulasta m'mayesero azachipatala, ndikuwonetsa kufunikira kotsata malingaliro azoyeserera zolemera zoperekedwa ndi wopanga.

Ngakhale wopanga samapereka chidziwitso chamankhwala chokhudzana ndi kutalika kwa nthawi yayitali, maphunziro azachipatala awonetsa kuti ANC imatenga masiku pafupifupi 10 mpaka 14 kuyambira tsiku lamankhwala a chemotherapy kuti ipezenso milingo yanthawi yomwe Neulasta amupatsa tsiku lotsatira chemotherapy.

Ndende ya Neulasta

Pambuyo poyendetsa pang'onopang'ono, kuchuluka kwa Neulasta kumachitika mozungulira maola 16 mpaka 120 pambuyo pa mlingo.

Zotsutsana

Neulasta imatsutsana ndi odwala omwe ali ndi mbiri yazovuta zomwe zimachitika kwa pegfilgrastim kapena filgrastim.

Yosungirako

Masirinji oyambira a Neulasta ayenera kukhala m'firiji pakati pa 36 ° F ndi 46 ° F (2 ° C ndi 8 ° C). Ma syringe amayenera kusungidwa mu katoni yoyambirira kuti itetezedwe ku kuwala. Mitsempha yomwe imasiya kutentha kwa nthawi yayitali kuposa maola 48 iyenera kutayidwa.

Osamaunditsa ma syringe. Koma majakisoniwo akayamba kuzizira, aikeni m'firiji musanagwiritse ntchito. Tayani masirinji aliwonse omwe akhala oundana nthawi yopitilira imodzi.

Zipangizo za Neulasta Onpro ziyenera kukhala m'firiji pakati pa 36 ° F ndi 46 ° F (2 ° C ndi 8 ° C) mpaka mphindi 30 musanagwiritse ntchito. Musasunge zida mu kutentha kwa maola oposa 12 musanagwiritse ntchito. Ngati matayala amasungidwa kutentha kwa nthawi yayitali kuposa maola 12, atayeni.

Chodzikanira: Medical News Today yachita kuyesetsa konse kuti zitsimikizidwe kuti zowona zonse ndizolondola, zonse, komanso zaposachedwa. Komabe, nkhaniyi sikuyenera kugwiritsidwa ntchito m'malo mwa chidziwitso ndi ukadaulo wa akatswiri pazachipatala. Muyenera kufunsa adotolo kapena akatswiri azaumoyo musanamwe mankhwala aliwonse. Zambiri zamankhwala zomwe zili pano zitha kusintha ndipo sizingapangidwe kuti zigwiritse ntchito, mayendedwe, zodzitetezera, machenjezo, kulumikizana ndi mankhwala, kusokonezeka, kapena zovuta zina. Kusapezeka kwa machenjezo kapena zidziwitso za mankhwala omwe apatsidwa sikuwonetsa kuti kuphatikiza mankhwala kapena mankhwalawa ndiwotetezeka, ogwira ntchito, komanso oyenera kwa odwala onse kapena ntchito zina zilizonse.

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