Febrile neutropenia: ndi chiyani, zimayambitsa ndi chithandizo

Zamkati

• Zimayambitsa febrile neutropenia
• Kodi chithandizo

Febrile neutropenia itha kufotokozedwa ngati kuchepa kwa ma neutrophil, omwe amapezeka pakuyesa magazi osakwana 500 / µL, omwe amagwirizanitsidwa ndi malungo pamwambapa kapena ofanana ndi 38ºC kwa ola limodzi. Izi zimachitika pafupipafupi kwa odwala khansa atatha chemotherapy ndipo zimatha kubweretsa zovuta ndi zovuta kuchipatala ngati sichichiritsidwa nthawi yomweyo.

Ma neutrophil ndiwo maselo akulu amwazi omwe amateteza ndikulimbana ndi matenda, mtengo wabwinobwino womwe umaganiziridwa pakati pa 1600 ndi 8000 / µL, zomwe zimatha kusiyanasiyana malinga ndi labotale. Pamene kuchuluka kwa ma neutrophil kuli kofanana kapena kupitirira 500 / µL, neutropenia yayikulu imalingaliridwa, kuti munthuyo atengeke mosavuta ndi matenda omwe amapezeka mwachilengedwe.

Zimayambitsa febrile neutropenia

Febrile neutropenia ndimavuto omwe amabwera odwala khansa omwe amalandira mankhwala a chemotherapy, pokhala chimodzi mwazomwe zimayambitsa kufa kwa odwalawa, popeza kuchepa kwa ma neutrophils kumawonjezera chiopsezo cha munthu kukhala ndi matenda akulu.

Kuphatikiza pa chemotherapy, febrile neutropenia imatha kuchitika chifukwa cha matenda opatsirana omwe amayambitsidwa ndi bowa, mabakiteriya ndi ma virus, makamaka kachilombo ka Epstein-Barr ndi hepatitis. Phunzirani pazomwe zimayambitsa neutropenia.

Kodi chithandizo

Chithandizo cha febrile neutropenia chimasiyanasiyana malinga ndi kuuma kwake. Odwala omwe amadziwika kuti ali ndi febrile neutropenia, momwe kuchuluka kwa ma neutrophil ndi ochepera kapena ofanana ndi 200 / µL, nthawi zambiri amathandizidwa pogwiritsa ntchito maantibayotiki a gulu la beta-lactams, m'badwo wachinayi wa cephalosporins kapena carbapenems. Kuphatikiza apo, kwa wodwala yemwe ali wosakhazikika kuchipatala kapena yemwe akumuganizira kuti ali ndi matenda opatsirana, angalimbikitsidwe kugwiritsa ntchito mankhwala ena olimbana ndi matendawa.

Pakakhala chiopsezo chochepa cha febrile neutropenia, wodwalayo amayang'aniridwa, ndipo kuwerengetsa magazi kwathunthu kumayenera kuchitika nthawi ndi nthawi kuti aone kuchuluka kwa ma neutrophils. Kuphatikiza apo, ngati matenda a fungal kapena bakiteriya atsimikiziridwa, kugwiritsa ntchito maantimicrobial, kaya maantibayotiki kapena antifungal, atha kulimbikitsidwa ndi adokotala kutengera wothandizirayo.

Febrile neutropenia ikachitika chemotherapy, tikulimbikitsidwa kuti mankhwala a maantibayotiki ayambe posachedwa ola limodzi mutayang'ana malungo.