Mafuta a Cannabidiol (CBD): ndi chiyani komanso phindu

Zamkati

• Momwe Mafuta a Cannabidiol Amagwirira Ntchito
• Zopindulitsa zaumoyo
• Zotsatira zoyipa

Mafuta a Cannabidiol, omwe amadziwikanso kuti CBD mafuta, ndi chinthu chomwe chimapezeka kuchokera ku chomeracho Mankhwala sativa, wodziwika kuti chamba, womwe umatha kuthana ndi nkhawa, kuthandizira kuthandizira kugona komanso kukhala ndi phindu pochiza khunyu.

Mosiyana ndi mankhwala ena osuta chamba, mafuta a cannabidiol alibe THC, yomwe ndi chamba chomwe chimayambitsa zovuta za psychotropic, monga kutaya chidziwitso ndi zosokoneza munthawi ndi malo, mwachitsanzo. Chifukwa chake, mafuta a cannabidiol amatha kugwiritsidwa ntchito pochiza. Dziwani zambiri za chamba.

Komabe, maphunziro owonjezera amafunikira kuti afotokozere zabwino za mafuta a CBD pamavuto aliwonse, komanso koyenera kwambiri.

Momwe Mafuta a Cannabidiol Amagwirira Ntchito

Zochita za mafuta a cannabidiol zimachitika makamaka chifukwa cha zomwe amachita pama receptors awiri omwe amapezeka mthupi, otchedwa CB1 ndi CB2. CB1 ili muubongo ndipo imakhudzana ndi kuwongolera kutulutsa kwa ma neurotransmitter ndi zochitika za neuronal, pomwe CB2 imapezeka m'magulu amitsempha, omwe amachititsa mayankho otupa komanso opatsirana.

Pogwira ntchito yolandirira CB1, cannabidiol imatha kuletsa zochitika za neuronal mopitilira muyeso, kuthandiza kupumula ndikuchepetsa zizindikilo zomwe zimakhudzana ndi nkhawa, komanso kuwongolera kuzindikira kwakumva kuwawa, kukumbukira, kulumikizana komanso kuzindikira. Pogwira ntchito yolandirira CB2, cannabidiol imathandizira potulutsa ma cytokines ndi maselo amthupi, omwe amathandiza kuchepetsa kupweteka ndi kutupa.

Zopindulitsa zaumoyo

Chifukwa cha momwe mafuta a CBD amagwirira ntchito mthupi, kugwiritsa ntchito kwake kumatha kubweretsa zabwino zathanzi komanso kulingaliridwa pochiza matenda ena:

• Khunyu: Kafukufuku wina wasonyeza kuti mafuta a cannabidiol amatha kuchepetsa pafupipafupi khunyu chifukwa cholumikizana ndi chinthuchi ndi ma CB1 amalandila amtundu muubongo, komanso ma receptors ena osadziwika a cannabidiol;
• Post-traumatic stress disorder: kafukufuku yemwe adachitika ndi anthu omwe adapezeka kuti ali ndi nkhawa pambuyo pozunzika adapeza kuti kugwiritsa ntchito cannabidiol kudapangitsa kusintha kwa zizindikilo za nkhawa komanso kuwonongeka kwazindikiritso, poyerekeza ndi gulu lomwe limathandizidwa ndi placebo, pomwe kuwonjezeka kwa zizindikirazo kunawonedwa;
• Kusowa tulo: Pogwiritsira ntchito malamulo a neuronal ndi kutulutsa ma neurotransmitters, mafuta a cannabidiol amatha kulimbikitsa kupumula, motero, amathandizira kuchiza tulo. Zinawonanso mu kafukufuku wina kuti kugwiritsa ntchito 25 mg ya mafuta a cannabidiol adatha kupititsa patsogolo kugona;
• Kutupa: Kafukufuku wopangidwa ndi makoswe adawonetsa kuti cannabidiol inali yothandiza kuthetsa ululu wokhudzana ndi kutupa, chifukwa zikuwoneka kuti zimalumikizana ndi zolandila zokhudzana ndi kumva kupweteka.

Onani zabwino za cannabidiol muvidiyo yotsatirayi:

Ngakhale pali zisonyezo, magwiridwe antchito, katundu komanso kusapezeka kwa zigawo za THC, zomwe zingapangitse mafuta a cannabidiol kuvomerezedwa ndi azachipatala komanso asayansi, zovuta zogwiritsa ntchito mafutawa pakadali pano sizinatsimikizidwebe, ndipo maphunziro owonjezera ndi anafunika kuthandiza kutsimikizira zotsatira za mafuta a CBD mwa anthu ambiri.

Mu 2018, Mankhwala Osokoneza Bongo (FDA) yavomereza kugwiritsa ntchito mankhwala, Epidiolex, omwe amangokhala ndi cannabidiol pochiza khunyu, komabe ANVISA pakadali pano sichinadziyimitse pokhudzana ndi kugulitsa mankhwala ku Brazil.

Mpaka pano, ANVISA yalola kutsatsa kwa Mevatyl, yomwe ndi mankhwala ozikidwa pa cannabidiol ndipo THC ikuwonetsedwa makamaka pochiza minyewa yaminyewa yomwe imachitika mu multiple sclerosis ndipo ntchito yake iyenera kuwonetsedwa ndi adotolo. Onani zambiri za Mevatyl ndi zomwe zikuwonetsa.

Zotsatira zoyipa

Kafukufuku wina apeza kuti zoyipa zamafuta a cannabidiol ndizokhudzana ndi kugwiritsidwa ntchito kosayenera kwa mankhwalawa, makamaka osanenedwa ndi dokotala kapena kuwonjezeka kozama, ndikutopa komanso kugona mokwanira, kutsekula m'mimba, kusintha kwa njala ndi kulemera, kukwiya, kutsegula m'mimba, kusanza ndi kupuma. Kuphatikiza apo, zapezeka kuti kuchuluka kwa ana opitilira 200 mg ya cannabidiol kumatha kukulitsa zizindikilo zokhudzana ndi nkhawa, kuwonjezera pakulimbikitsa kuwonjezeka kwa mtima ndi kusinthasintha kwa malingaliro.

Zinapezekanso kuti cannabidiol imatha kusokoneza ntchito ya enzyme yopangidwa ndi chiwindi, cytochrome P450, yomwe, mwazinthu zina, imayambitsa kutha kwa mankhwala ndi poizoni. Chifukwa chake, CBD imatha kukhudza zomwe mankhwala ena amabwera, komanso amachepetsa chiwindi kutha ndikuchotsa poizoni, zomwe zimatha kuyambitsa chiwopsezo cha chiwindi.

Kuphatikiza apo, kugwiritsa ntchito mafuta a cannabidiol sikuwonetsedwa kwa amayi apakati, omwe akukonzekera kutenga pakati kapena omwe akuyamwitsa, chifukwa zidapezeka kuti CBD imatha kupezeka mkaka wa m'mawere, kuphatikiza pakuperekera kwa mwana wosabadwayo nthawi yapakati .