Kuyesa kwa Pharmacogenetic
Zamkati
- Kuyesa kwa mankhwala osokoneza bongo ndi chiyani?
- Amagwiritsidwa ntchito yanji?
- Chifukwa chiyani ndikufunika kuyezetsa mankhwala osokoneza bongo?
- Kodi chimachitika ndi chiani poyesa mankhwala?
- Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?
- Kodi pali zoopsa zilizonse pamayeso?
- Kodi zotsatirazi zikutanthauza chiyani?
- Kodi pali china chilichonse chomwe ndikufunika kudziwa pokhudzana ndi kuyezetsa mankhwala?
- Zolemba
Kuyesa kwa mankhwala osokoneza bongo ndi chiyani?
Pharmacogenetics, yotchedwanso pharmacogenomics, ndikuwunika momwe majini amakhudzira momwe thupi limayankhira mankhwala ena. Chibadwa ndi mbali za DNA zomwe zapatsidwa kuchokera kwa amayi ndi abambo anu. Amanyamula zidziwitso zomwe zimatsimikizira mikhalidwe yanu yapadera, monga kutalika ndi mtundu wamaso. Ma jini anu amathanso kukhudza momwe mankhwala osokoneza bongo angakhale otetezeka kwa inu.
Chibadwa chingakhale chifukwa chake mankhwala omwewo pamlingo womwewo amakhudza anthu m'njira zosiyanasiyana. Chibadwa chingakhale chifukwa chomwe anthu ena amakhala ndi zovuta zoyipa zamankhwala, pomwe ena alibe.
Kuyesa kwa Pharmacogenetic kumayang'ana majini ena kuti athandizire kudziwa mitundu ya mankhwala ndi miyezo yomwe ingakhale yoyenera kwa inu.
Mayina ena: pharmacogenomics, pharmacogenomic kuyesa
Amagwiritsidwa ntchito yanji?
Kuyesa kwa Pharmacogenetic kumatha kugwiritsidwa ntchito:
- Fufuzani ngati mankhwala ena ali othandiza kwa inu
- Pezani zomwe mulingo wabwino ungakhale kwa inu
- Losera ngati mungakhale ndi vuto lalikulu kuchokera kumankhwala
Chifukwa chiyani ndikufunika kuyezetsa mankhwala osokoneza bongo?
Wothandizira zaumoyo wanu amatha kuyitanitsa mayesowa musanayambe mankhwala ena, kapena ngati mukumwa mankhwala omwe sakugwira ntchito kapena / kapena oyambitsa zovuta zina.
Mayeso a Pharmacogenetic amapezeka kokha pamankhwala ochepa. M'munsimu muli mankhwala ndi majini omwe angayesedwe. (Mayina a Gene nthawi zambiri amaperekedwa m'makalata ndi manambala.)
Mankhwala | Chibadwa |
---|---|
Warfarin: magazi ochepa | CYP2C9 ndi VKORC1 |
Plavix, magazi ochepera magazi | CYP2C19 |
Ma antidepressants, mankhwala akhunyu | Gawo #: CYP2D6, CYPD6 CYP2C9, CYP1A2, SLC6A4, HTR2A / C |
Tamoxifen, mankhwala a khansa ya m'mawere | CYPD6 |
Mankhwala oletsa antipsychotic | Kufotokozera: DRD3, CYP2D6, CYP2C19, CYP1A2 |
Mankhwala othandizira kusowa chidwi | D4D4 |
Carbamazepine, chithandizo cha khunyu | HLA-B 1502 |
Abacavir, chithandizo cha HIV | HLA-B 5701 |
Opioids | OPRM1 |
Statins, mankhwala omwe amachiza cholesterol yambiri | SLCO1B1 |
Chithandizo cha khansa ya m'magazi yaubwana ndi zovuta zina zama autoimmune | TMPT |
Kodi chimachitika ndi chiani poyesa mankhwala?
Kuyezetsa kumachitika nthawi zambiri pamwazi kapena malovu.
Kuyezetsa magazi, Katswiri wa zamankhwala adzatenga magazi kuchokera mumtsinje wamkono mwanu, pogwiritsa ntchito singano yaying'ono. Singanoyo italowetsedwa, magazi ang'onoang'ono amatengedwa mu chubu choyesera. Mutha kumva kuluma pang'ono singano ikamalowa kapena kutuluka. Izi nthawi zambiri zimatenga mphindi zosakwana zisanu.
Kuyesa malovu, Funsani wothandizira zaumoyo wanu kuti akupatseni malangizo a momwe mungaperekere chitsanzo chanu.
Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?
Nthawi zambiri simusowa kukonzekera kwapadera kokayezetsa magazi. Ngati mukuyezetsa malovu, simuyenera kudya, kumwa, kapena kusuta kwa mphindi 30 mayeso asanayesedwe.
Kodi pali zoopsa zilizonse pamayeso?
Pali chiopsezo chochepa kwambiri choyesedwa magazi. Mutha kukhala ndi ululu pang'ono kapena kuvulala pamalo pomwe singano idayikidwapo, koma zizindikiro zambiri zimatha msanga.
Palibe chiopsezo chilichonse kukayezetsa malovu.
Kodi zotsatirazi zikutanthauza chiyani?
Ngati mwayezetsa musanayambe kumwa mankhwala, mayesowo atha kuwonetsa ngati mankhwala atha kukhala othandiza komanso / kapena ngati muli pachiwopsezo chazovuta zina. Mayesero ena, monga mankhwala ena omwe amathandiza khunyu ndi kachilombo ka HIV, angasonyeze ngati muli pachiopsezo chowopsa. Ngati ndi choncho, wothandizira wanu ayesa kupeza njira ina.
Kuyesedwa komwe kumachitika kale komanso mukamalandira chithandizo kumatha kuthandizira omwe amakuthandizani kuti azindikire mlingo woyenera.
Ngati muli ndi mafunso pazotsatira zanu, lankhulani ndi omwe amakuthandizani.
Dziwani zambiri zamayeso a labotale, magawo owerengera, ndi zotsatira zakumvetsetsa.
Kodi pali china chilichonse chomwe ndikufunika kudziwa pokhudzana ndi kuyezetsa mankhwala?
Kuyesa kwa Pharmacogenetic kumangogwiritsidwa ntchito kuti mupeze yankho la munthu ku mankhwala enaake. Sizofanana ndi kuyesa majini. Mayeso ambiri amtundu amagwiritsidwa ntchito kuthandizira kuzindikira matenda kapena chiopsezo cha matenda, kuzindikira ubale wapabanja, kapena kuzindikira wina wofufuza milandu.
Zolemba
- Hefti E, Blanco J. Kulemba Kuyesa kwa Pharmacogenomic ndi Ma Code Atsopano a terminology (CPT), Kuwunika Zakale ndi Zamakono. J AHIMA [Intaneti]. 2016 Jan [adatchula 2018 Jun 1]; 87 (1): 56-9. Ipezeka kuchokera: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998735
- Kuyesa kwa Labu Paintaneti [Intaneti]. Washington DC: American Association for Clinical Chemistry; c2001–2018. Kuyesa kwa Pharmacogenetic; [yasinthidwa 2018 Jun 1; yatchulidwa 2018 Jun 1]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://labtestsonline.org/tests/pharmacogenetic-tests
- Kuyesa kwa Labu Paintaneti [Intaneti]. Washington DC: American Association for Clinical Chemistry; c2001–2018. Dziko Lonse La Kuyesedwa Kwachibadwa; [yasinthidwa 2017 Nov 6; yatchulidwa 2018 Jun 1]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://labtestsonline.org/articles/genetic-testing?start=4
- Chipatala cha Mayo: Center for Individualised Medicine [Internet]. Mayo Foundation for Medical Education and Research; c1998–2018. Kuyesa Mankhwala Osokoneza Bongo; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: http://mayoresearch.mayo.edu/center-for-individualized-medicine/drug-gene-testing.asp
- Chipatala cha Mayo: Center for Individualised Medicine [Internet]. Mayo Foundation for Medical Education and Research; c1998–2018. CYP2D6 / Tamoxifen Pharmacogenomic Lab Test; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 5].Ipezeka kuchokera: http://mayoresearch.mayo.edu/center-for-individualized-medicine/cyp2d6-tamoxifen.asp
- Chipatala cha Mayo: Center for Individualised Medicine [Internet]. Mayo Foundation for Medical Education and Research; c1998–2018. HLA-B 1502 / Carbamazepine Pharmacogenomic Lab Test; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab1502-carbamazephine.asp
- Chipatala cha Mayo: Center for Individualised Medicine [Internet]. Mayo Foundation for Medical Education and Research; c1998–2018. HLA-B 5701 / Abacavir Pharmacogenomic Lab Test; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab5701-abacavir.asp
- Chipatala cha Mayo: Mayo Medical Laboratories [Internet]. Mayo Foundation for Medical Education and Research; c1995–2018. ID Yoyesera: PGXFP: Gulu Loyang'ana Kwambiri la Pharmacogenomics: Chitsanzo; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.mayomedicallaboratories.com/test-catalog/Specimen/65566
- National Cancer Institute [Intaneti]. Bethesda (MD): Dipatimenti ya Zaumoyo ndi Zantchito ku U.S. Buku la NCI lotanthauzira za Khansa: jini; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q;=gene
- National Heart, Lung, ndi Blood Institute [Internet]. Bethesda (MD): Dipatimenti ya Zaumoyo ndi Zantchito ku U.S. Kuyesa Magazi; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 3]. Ipezeka kuchokera: https://www.nhlbi.nih.gov/health-topics/blood-tests
- NIH National Institute of General Medical Sayansi [Intaneti]. Bethesda (MD): Dipatimenti ya Zaumoyo ndi Zantchito ku U.S. Mankhwala; [yasinthidwa 2017 Oct; yatchulidwa 2018 Jun 1]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: https://www.nigms.nih.gov/education/Pages/factsheet-pharmacogenomics.aspx
- NIH U.S. National Library of Medicine: Genetics Home Reference [Internet]. Bethesda (MD): Dipatimenti ya Zaumoyo ndi Zantchito ku U.S. Kodi pharmacogenomics ndi chiyani?; 2018 Meyi 29 [yatchulidwa 2018 Jun 1]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics
- UF Health: University of Florida Health [Intaneti]. Yunivesite ya Florida; c2018. Momwe majini anu amakhudzira mankhwala omwe ali oyenera kwa inu; 2016 Jan 11 [yasinthidwa 2018 Jun 1; yatchulidwa 2018 Jun 1]; [pafupifupi zowonetsera 2]. Ipezeka kuchokera: https://ufhealth.org/blog/how-your-genes-influence-what-medicines-are-right-you
- Chipatala cha UW Health American Family Children [Internet]. Madison (WI): Zipatala za University of Wisconsin ndi Clinics Authority; c2018. Ana Thanzi: Pharmacogenomics; [adatchula 2018 Jun 1]; [pafupifupi zowonetsera 4]. Ipezeka kuchokera: https://www.uwhealthkids.org/kidshealth/en/parents/pharmacogenomics.html/
Zomwe zili patsamba lino siziyenera kugwiritsidwa ntchito m'malo mwa chithandizo chamankhwala kapena upangiri. Lumikizanani ndi othandizira azaumoyo ngati muli ndi mafunso okhudzana ndi thanzi lanu.