Thalidomide

Zamkati

• Mtengo
• Zisonyezero
• Momwe mungagwiritsire ntchito
• Zotsatira zoyipa
• Zotsutsana

Thalidomide ndi mankhwala omwe amagwiritsidwa ntchito pochiza khate lomwe ndi matenda omwe amayamba chifukwa cha bakiteriya omwe amakhudza khungu ndi mitsempha, zomwe zimapangitsa kuti munthu asamve bwino, kufooka kwa minofu ndi kufooka. Kuphatikiza apo, imalimbikitsidwanso kwa odwala omwe ali ndi HIV komanso lupus.

Mankhwalawa ogwiritsidwa ntchito pakamwa, mwa mapiritsi, atha kugwiritsidwa ntchito pokhapokha ngati dokotala akuvomereza ndipo ndiwotsutsana kotheratu pathupi komanso oletsedwa kwa azimayi azaka zobereka, pakati pa kutha msinkhu ndi kusamba, chifukwa zimayambitsa kusokonekera kwa mwana, monga kusowa kwa milomo, mikono ndi miyendo, kuchuluka kwa zala, hydrocephalus kapena kusayenda bwino kwa mtima, matumbo ndi impso, mwachitsanzo. Pachifukwa ichi, pakagwiritsidwe ntchito ka mankhwalawa posonyeza zamankhwala, nthawi yofunikira iyenera kusainidwa.

Mtengo

Mankhwalawa amangolekezera kugwiritsidwa ntchito kuchipatala ndipo amaperekedwa kwaulere ndi boma ndipo, chifukwa chake, sagulitsidwa m'masitolo.

Zisonyezero

Kugwiritsa ntchito Thalidomide kukuwonetsedwa pochiza:

• Khate, womwe ndi mtundu wa khate wachiwiri kapena mtundu wa erythema nodosum;
• Edzi, chifukwa amachepetsa kutentha thupi, kufooka komanso kufooka kwa minofu:
• Lupus, Matenda olumikizidwa ndi otsutsana, chifukwa kutupa kumachepa.

Kuyamba kwa mankhwalawa kumatha kusiyanasiyana pakati pa masiku awiri mpaka miyezi itatu, kutengera chifukwa cha mankhwalawo ndipo atha kugwiritsidwa ntchito ndi azimayi omwe sanakwanitse zaka zobereka komanso ali ndi ana opitilira zaka 12.

Momwe mungagwiritsire ntchito

Kugwiritsa ntchito mankhwalawa m'mapiritsi kumangoyambitsidwa ndi dokotala komanso kutsatira njira inayake yogwiritsa ntchito mankhwalawa yomwe imafuna kuti wodwalayo asayine fomu yovomereza. Nthawi zambiri, dokotala amalimbikitsa:

• Chithandizo cha khate mtundu wamtundu kapena mtundu wachiwiri pakati pa 100 mpaka 300 mg, kamodzi patsiku, nthawi yogona kapena osachepera, ola limodzi mutadya chakudya chamadzulo;
• Chithandizo cha elepromatous nodular ritema, yambani mpaka 400 mg patsiku, ndikuchepetsa kuchepa kwa masabata a 2, mpaka mukafike pamlingo wokonza, womwe uli pakati pa 50 ndi 100 mg patsiku.
• Matenda ofooketsa, wokhudzana ndi HIV: 100 mpaka 200 mg kamodzi patsiku nthawi yogona kapena ola limodzi mutadya kotsiriza.

Mukamalandira chithandizo sayenera kukhala ndi zibwenzi zapamtima ndipo ngati zingachitike, njira ziwiri zolerera ziyenera kugwiritsidwa ntchito nthawi imodzi, monga piritsi yolerera, jakisoni kapena implant ndi kondomu kapena diaphragm. Kuphatikiza apo, ndikofunikira kuyamba kupewa kupewa kutenga pakati mwezi umodzi musanalandire chithandizo komanso kwa milungu inayi itatha.

Pankhani ya amuna omwe amagonana ndi akazi azaka zobereka, ayenera kugwiritsa ntchito kondomu pamtundu uliwonse wapamtima.

Zotsatira zoyipa

Zotsatira zoyipa kwambiri zogwiritsa ntchito mankhwalawa ngati agwiritsidwa ntchito ndi mayi wapakati, zomwe zimabweretsa zovuta m'mwana. Kuphatikiza apo, zimatha kubweretsa kumva kulasalasa, kupweteka m'manja, mapazi ndi matenda amitsempha.

Kusalolera m'mimba, kuwodzera, chizungulire, kuchepa magazi m'thupi, leukopenia, leukemia, purpura, nyamakazi, kupweteka kwa msana, kuthamanga kwa magazi, mitsempha yayikulu thrombosis, angina, matenda amtima, kusokonezeka, mantha, sinusitis, chifuwa, kupweteka m'mimba, kutsegula m'mimba, kapena ndende kumachitika. chiberekero, conjunctivitis, khungu louma.

Zotsutsana

Kugwiritsa ntchito mankhwalawa ndikotsutsana kwathunthu pamimba chifukwa zimayambitsa kusokonekera mwa mwana, monga kusowa kwa miyendo, mikono, milomo kapena makutu, kuphatikiza pakulephera kwa mtima, impso, matumbo ndi chiberekero, mwachitsanzo.

Kuphatikiza apo, 40% ya ana amamwalira atangobadwa kumene ndipo amatsitsidwanso nthawi yoyamwitsa, chifukwa zomwe zimadziwika sizidziwika. Sitha kugwiritsidwanso ntchito ngati Matigari ali ndi vuto la Thalidomide kapena chilichonse mwazigawo zake.