Mlembi: Eugene Taylor
Tsiku La Chilengedwe: 16 Ogasiti 2021
Sinthani Tsiku: 17 Novembala 2024
Anonim
How to Inject Taltz
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Zamkati

Taltz ndi chiyani?

Taltz ndi mankhwala odziwika ndi dzina la mankhwala. Ndizovomerezeka kuti zithetse izi:

Kwa plaque psoriasis, Taltz imatha kuperekedwa kwa akulu ndi ana azaka 6 kapena kupitilira apo. Koma pazogwiritsa ntchito zina zonse zovomerezeka, Taltz imangolembedwa kwa akuluakulu.


Taltz muli yogwira mankhwala ixekizumab. Ndi mtundu wa mankhwala a biologic (mankhwala opangidwa kuchokera m'maselo amoyo) otchedwa humanized monoclonal antibody.

Taltz imabwera m'njira ziwiri: jakisoni woyambira komanso cholembera chodzipangira chokha. Mankhwalawa amaperekedwa ndi jakisoni pansi pa khungu lanu (jakisoni wamagetsi). Wothandizira zaumoyo wanu amakupatsani jakisoni poyamba. Kenako atha kukuphunzitsani momwe mungadziperekere nokha kunyumba.

Kuchita bwino

Kuti mumve zambiri zantchito ya Taltz pochiza zinthu zomwe zatchulidwa pamwambapa, onani gawo la "Taltz uses" gawo ili m'munsiyi.

Taltz generic

Taltz imangopezeka ngati mankhwala odziwika ndi dzina. Sikupezeka pakadali pano mu mawonekedwe achibadwa. (Mankhwala achibadwa ndi mankhwala enieni a mankhwala omwe ali ndi dzina lodziwika.)

Taltz ili ndi chinthu chimodzi chogwiritsira ntchito mankhwala: ixekizumab.

Mlingo wa Taltz

Mlingo wa Taltz womwe dokotala wanu amakupatsani umadalira momwe mungamuthandizire.

Chidziwitso chotsatirachi chimalongosola miyezo yomwe amagwiritsidwa ntchito kwambiri kapena amalimbikitsidwa. Komabe, onetsetsani kuti mumamwa mankhwalawo ndikutsatira nthawi yomwe dokotala akukulemberani.


Mitundu ya mankhwala ndi mphamvu

Taltz imapezeka mwamphamvu imodzi: mamiligalamu 80 pa mamililita (mg / mL).

Mankhwalawa amabwera m'njira ziwiri: syringe yogwiritsa ntchito kamodzi komanso cholembera chogwiritsa ntchito kamodzi. Mutha kupeza kuti mawonekedwe amodzi ndiosavuta kugwiritsa ntchito kuposa ena. Lankhulani ndi dokotala za mawonekedwe omwe angakupindulitseni.

Mankhwalawa amaperekedwa ndi jakisoni pansi pa khungu lanu (jakisoni wamagetsi). Wothandizira zaumoyo wanu amakupatsani jakisoni poyamba. Kenako atha kukuphunzitsani momwe mungadziperekere nokha kunyumba.

Mlingo wa nyamakazi ya psoriatic

Pa psoriatic arthritis, mlingo wanu woyamba wa Taltz udzaperekedwa ngati majakisoni awiri a 80-mg (okwanira 160 mg) tsiku lomwelo. Pambuyo pake, muyeso wanu wokonzekera udzakhala jekeseni umodzi wa 80-mg kamodzi pamasabata anayi malinga ndi momwe dokotala akuwalimbikitsira.

Zindikirani: Kuti mudziwe zambiri zamatenda a psoriatic, onani gawo la "Taltz uses" pansipa.

Mlingo wa psoriasis yolimbitsa kwambiri

Pa plaque psoriasis, mlingo wanu woyamba wa Taltz udzakhala jakisoni awiri 80-mg (okwanira 160 mg) tsiku lomwelo. Pambuyo pake, mudzakhala ndi jakisoni 80 mg kamodzi pamasabata awiri pamasabata 12. Ndiye kuti muyeso wanu wokonzekera udzakhala jakisoni kamodzi pamasabata 4 aliwonse malinga ndi momwe dokotala akuvomerezera.


Zindikirani: Kuti mudziwe zambiri za plaque psoriasis, onani "Taltz ntchito" gawo ili m'munsiyi.

Mlingo wa nyamakazi ya psoriatic komanso psoriasis yolimbitsa thupi kwambiri

Ngati muli ndi psoriatic arthritis ndi plaque psoriasis, mugwiritsa ntchito mulingo wa Taltz ndi dosing ndandanda ya psoriasis yolimbitsa thupi. Onani gawo ili pamwambapa kuti mumve izi.

Zindikirani: Kuti mudziwe zambiri za psoriatic nyamakazi ndi plaque psoriasis, onani "Taltz ntchito" gawo ili m'munsiyi.

Mlingo wa non-radiographic axial spondyloarthritis

Kwa non-radiographical axial spondyloarthritis (nr-axSpA), mudzalandira jakisoni wa 80-mg wa Taltz kamodzi pamasabata anayi.

Zindikirani: Kuti mudziwe zambiri za nr-axSpA, onani gawo la "Taltz ntchito" pansipa.

Mlingo wa ankylosing spondylitis

Kwa ankylosing spondylitis (AS), mlingo wanu woyamba wa Taltz udzakhala jakisoni wa 80-mg (wokwanira 160 mg) tsiku lomwelo. Pambuyo pake, mulingo wanu wokonzanso udzakhala jekeseni imodzi ya 80-mg kamodzi pakatha milungu inayi.

Zindikirani: Kuti mudziwe zambiri za AS, onani gawo la "Taltz ntchito" pansipa.

Ndingatani ngati ndaphonya mlingo?

Ngati mwaphonya jakisoni, muyenera kukhala naye posachedwa. Ndiye ingotengani jakisoni wanu wotsatira pomwe umayenera kutero. Koma ngati mwaphonya jakisoni ndipo simutenga nthawi yotsatira, pemphani dokotala kuti akupatseni malangizo pazomwe mungachite.

Pofuna kuthandizira kuti musaphonye mlingo, yesani kukhazikitsa chikumbutso pafoni yanu. Timer ya mankhwala ingakhale yothandiza, nayenso.

Kodi ndiyenera kugwiritsa ntchito mankhwalawa nthawi yayitali?

Taltz amayenera kugwiritsidwa ntchito ngati chithandizo chanthawi yayitali. Ngati inu ndi adotolo mukuganiza kuti Taltz ikugwirani ntchito bwino, ndizotheka kuti mupitiliza kuigwiritsa ntchito kwa nthawi yayitali.

Zotsatira za Taltz

Taltz imatha kuyambitsa zovuta kapena zoyipa. Mndandanda wotsatira uli ndi zovuta zina zomwe zingachitike mukamamwa Taltz. Mndandandawu sungaphatikizepo zovuta zonse zomwe zingachitike.

Kuti mumve zambiri pazomwe zingachitike chifukwa cha Taltz, lankhulani ndi dokotala kapena wamankhwala. Amatha kukupatsirani malangizo amomwe mungathetsere mavuto omwe angakhale ovuta.

Zindikirani: Food and Drug Administration (FDA) imatsata zotsatirapo zamankhwala omwe avomereza. Ngati mukufuna kufotokozera FDA zotsatira zoyipa zomwe mudakhala nazo ndi Taltz, mutha kutero kudzera ku MedWatch.

Zotsatira zofala kwambiri

Zotsatira zofala kwambiri za Taltz zitha kuphatikiza:

  • zochita za jakisoni (kufiira ndi kuwawa mozungulira jekeseni)
  • matenda opatsirana apamwamba, monga chimfine kapena chimfine
  • nseru
  • matenda a mafangasi, monga phazi la wothamanga
  • conjunctivitis (diso la pinki)

Zambiri mwa zotsatirazi zimatha kutha masiku angapo kapena milungu ingapo. Ngati ali ovuta kwambiri kapena osapita, lankhulani ndi dokotala kapena wamankhwala.

Zotsatira zoyipa

Zotsatira zoyipa zochokera ku Taltz sizachilendo, koma zimatha kuchitika. Itanani dokotala wanu nthawi yomweyo ngati muli ndi zovuta zina. Itanani 911 ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukukumana ndi zachipatala.

Zotsatira zoyipa, zomwe zafotokozedwa mwatsatanetsatane pansipa mu "Zotsatira zoyipa," ndi izi:

  • aakulu thupi lawo siligwirizana
  • Matenda otupa (IBD), monga matenda a Crohn kapena ulcerative colitis
  • chiopsezo chowonjezeka cha matenda, monga chifuwa chachikulu (TB)

Zotsatira zoyipa mwa ana

Kafukufuku wamankhwala adayang'ana ana azaka zapakati pa 6 mpaka 18 omwe anali ndi psoriasis. Pakafukufukuyu, mitundu yazovuta zomwe zimawonedwa mwa ana komanso kuti zidachitika kangati zinali zofanana ndi zomwe zimawoneka mwa akulu. Kupatula izi, zotsatirazi zimachitika kawirikawiri mwa ana kuposa achikulire:

  • conjunctivitis (diso la pinki)
  • chimfine
  • ming'oma (zotupa pakhungu)

Pakafukufuku womwewo, matenda a Crohn adachitika 0.9% pafupipafupi mwa ana omwe amatenga Taltz kuposa momwe zimachitikira ana omwe amatenga placebo. (A placebo ndi mankhwala opanda mankhwala.)

Zotsatira zoyipa

Mutha kudabwa kuti zovuta zina zimachitika kangati ndi mankhwalawa, kapena ngati zovuta zina zake zimakhudza. Nazi zina mwazovuta zomwe mankhwalawa angapangitse kapena sangayambitse.

Matupi awo sagwirizana

Monga momwe zimakhalira ndi mankhwala ambiri, anthu ena amatha kusokonezeka atalandira Taltz. Zizindikiro za kuchepa pang'ono zimatha kuphatikiza:

  • zotupa pakhungu
  • kuyabwa
  • Kutentha (kutentha ndi kufiira pakhungu lanu)

Zomwe zimayambitsa matendawa zimakhala zochepa koma ndizotheka. Zizindikiro za kuyanjana kwambiri ndi izi:

  • angioedema (kutupa pansi pa khungu lanu, makamaka m'maziso anu, milomo, kapena masaya)
  • kutupa lilime, pakamwa, kapena pakhosi
  • kuvuta kupuma
  • kufinya pachifuwa
  • kumva kukomoka

M'maphunziro azachipatala, zovuta zomwe zidachitika zimachitika mu 0,1% kapena ochepera mwa anthu omwe adalandira Taltz. Izi zimayambitsa angioedema ndi urticaria (totupa pakhungu lotchedwanso ming'oma).

Itanani dokotala wanu nthawi yomweyo ngati muli ndi vuto lalikulu ku Taltz. Koma itanani 911 kapena nambala yanu yadzidzidzi yakomweko ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukudwala mwadzidzidzi.

Jekeseni wa jakisoni

Mutha kukhala ndi khungu komwe mumalandira jakisoni wa Taltz. Ndipo izi zimatha kuyambitsa zizindikiro monga kufiira kapena kupweteka.

M'maphunziro azachipatala, 17% ya anthu omwe ali ndi plaque psoriasis omwe adalandira Taltz adachitapo kanthu, monga kufiira kapena kupweteka, pamalo obayira. Zambiri mwazimenezi zinali zofatsa kapena zochepa ndipo sizinapangitse anthu kusiya mankhwala.

Nthawi iliyonse mukabaya Taltz, muyenera kusankha malo ena pathupi lanu kuposa jakisoni womaliza. Ngati muli ndi vuto la khungu lomwe ndi loopsa kapena silingathe masiku angapo, onani dokotala wanu.

Kuchulukitsa chiwopsezo cha matenda

Taltz ikhoza kufooketsa chitetezo chanu chamthupi. Ngati chitetezo chanu cha mthupi sichikhala chokwanira kulimbana ndi majeremusi, mumatha kutenga matenda.

M'maphunziro azachipatala, 27% ya anthu omwe ali ndi plaque psoriasis omwe adalandira Taltz kwa milungu 12 adadwala. Nazi zina mwazofufuza:

  • Ambiri mwa matendawa anali ofatsa. Matenda 0,4% okha ndi omwe amawoneka kuti ndi akulu, monga chibayo.
  • Matenda ofala kwambiri anali matenda opuma monga kukhosomola, chimfine, kapena matenda am'mero.
  • Matenda ena amaphatikizapo conjunctivitis (diso la pinki) ndi matenda a mafangasi, monga thrush ya pakamwa kapena phazi la wothamanga.
  • M'maphunziro awa, 23% ya anthu omwe adalandira placebo (chithandizo chopanda mankhwala osokoneza bongo) nawonso adadwala.
  • Mwa anthu omwe adalandira chithandizo cha Taltz kwa milungu 60, 57% adalandira kachilombo poyerekeza ndi 32% omwe adalandira malowa.

Kuwunika komanso kuwunika ngati matenda akutuluka

Ngati muli ndi zizindikiro za matenda, lankhulani ndi dokotala kapena wamankhwala. Amatha kulangiza chithandizo. Zizindikiro za matenda ang'onoang'ono atha kukhala:

  • malungo
  • chifuwa
  • chikhure
  • maso ofiira komanso owawa
  • malo ofiira komanso owawa pakhungu
  • zigamba zoyera mkamwa mwako
  • kutentha kapena kupweteka pokodza

Ndikofunika kwambiri kukaonana ndi dokotala ngati matendawa sakuwonekeratu. Kupanda kutero, zitha kukhala zowopsa kwambiri.

Musanayambe kumwa mankhwala ndi Taltz, dokotala wanu amayang'ana ngati pali matenda aliwonse, monga chifuwa chachikulu (TB), matenda am'mapapo. Ngati muli ndi zizindikiro zilizonse za TB mukamalandira chithandizo, ndikofunikira kuyimbira dokotala nthawi yomweyo. Zizindikirozi ndi monga:

  • malungo
  • kupweteka kwa minofu
  • kuonda osayesa
  • chifuwa choipa chomwe chimatha milungu itatu kapena kupitilira apo
  • kutsokomola magazi kapena ntchofu
  • kupweteka pachifuwa
  • thukuta usiku

Kupewa matenda panthawi ya chithandizo cha Taltz

Pofuna kupewa kutenga matenda mukamamwa Taltz, sambani m'manja nthawi zambiri. Komanso, pewani kucheza kwambiri ndi anthu omwe ali ndi matenda (makamaka chifuwa, chimfine, kapena chimfine).

Ndipo funsani dokotala wanu ngati pali katemera aliyense yemwe muyenera kulandira musanayambe kumwa Taltz. (Onani "Taltz ndikukhala ndi katemera" mu gawo la "Kuyanjana kwa Taltz" kuti mudziwe zambiri.)

Matenda otupa

Ngati mutenga Taltz, pali chiopsezo chochepa kuti mungadwale matenda opatsirana (IBD). IBD ndi gulu la matenda omwe amachititsa kutupa (kutupa) m'magawo anu am'mimba. Matendawa amaphatikizapo matenda a Crohn's and ulcerative colitis.

Ngati muli ndi IBD, Taltz amatha kuipitsa, koma izi ndizochepa. M'maphunziro azachipatala, matenda a Crohn adachitika mwa anthu 0,1% omwe adalandira Taltz. Ndipo anthu 0,2% omwe adalandira Taltz anali ndi zilonda zam'mimba zatsopano kapena zowonjezereka.

Muyenera kuwona dokotala wanu ngati muli ndi zizindikiro zatsopano kapena zowonjezereka za IBD. Izi zingaphatikizepo:

  • kupweteka m'mimba mwako (m'mimba)
  • kutsegula m'mimba, wopanda magazi
  • kuonda

Kulemera kapena kuwonda (osati zotsatira zoyipa)

Kulemera ndi kuchepa thupi sikunanenedwe m'maphunziro azachipatala a Taltz. Komabe, kuonda kungakhale chizindikiro cha chifuwa chachikulu (TB) kapena matenda opatsirana am'mimba (IBD). Ndipo mikhalidwe yonseyi ndi zotsatira zoyipa za Taltz. Chifukwa chake ngati muchepetsa thupi mukamamwa Taltz, ndikofunikira kwambiri kukaonana ndi dokotala wanu.

Ngati muli ndi nkhawa zokhudzana ndi kunenepa kapena kuchepa thupi, lankhulani ndi dokotala wanu.

Kutaya tsitsi (osati zotsatira zoyipa)

Kutayika kwa tsitsi sikunawoneke m'maphunziro azachipatala a Taltz. Komabe, kumeta tsitsi kumatha kukhala chifukwa cha psoriasis yayikulu, mtundu wa plaque psoriasis womwe ungathe kuchiritsidwa ndi Taltz. Mwa kukanda khungu lanu kapena kutulutsa sikelo, mutha kumeta tsitsi lanu.

Ngati mukudandaula za kutayika kwa tsitsi, lankhulani ndi dokotala wanu.

Matenda okhumudwa (osati zotsatira zoyipa)

Matenda okhumudwa sanatchulidwe ngati zoyipa m'maphunziro azachipatala a Taltz. Komabe, kukhumudwa kumakhala kofala kwa anthu omwe ali ndi psoriasis kapena psoriatic nyamakazi, omwe Taltz amagwiritsidwa ntchito pochiza.

Kafukufuku wina adasanthula momwe Taltz idakhudzira zizindikilo za kukhumudwa kwa anthu omwe ali ndi psoriasis. Ofufuza apeza kuti pafupifupi 40% ya anthu omwe adalandira Taltz kwa milungu 12 achira pazizindikiro zawo zakukhumudwa.

Matenda akhungu monga psoriasis atha kukhala ndi gawo lofunikira pamaganizidwe. Ngati mukumva chisoni, kupsinjika, kapena kuda nkhawa, onetsetsani kuti mwalankhula ndi adotolo za izi. Nthawi zina kungomufotokozera zakukhosi kwanu kungakhale kothandiza. Koma ngati dokotala akuganiza kuti mukumva kukhumudwa, mungafunike chithandizo chake. Izi zitha kubwera ngati chithandizo chamaganizidwe kapena mankhwala.

Ziphuphu (osati zotsatira zoyipa)

Ziphuphu sizinatchulidwe ngati zoyipa m'maphunziro azachipatala a Taltz. Komabe, Taltz atavomerezedwa, anthu ochepa adatinso [KD1] [AK2] ali ndi ziphuphu kapena zotupa pakhungu. Koma milanduyi inali yosowa, ndipo sizikudziwika ngati Taltz adayambitsa ziphuphu.

Mankhwala a Psoriasis nthawi zina amagwiritsidwa ntchito pochiza ziphuphu zamtundu, zotchedwa acne inversa (kapena hidradenitis suppurativa). Izi ndichifukwa choti ziphuphu zakumaso zimaphatikizira khungu lopweteka, lotupa, monga psoriasis.

Koma Taltz sanaphunzirepo anthu omwe ali ndi ziphuphu zamtundu uliwonse. Pakadali pano, mankhwala okhawo omwe amavomerezedwa kuti athetse ziphuphu zakumaso ndi Humira (adalimumab).

Ngati mukuda nkhawa ndi ziphuphu, kambiranani ndi dokotala wanu. Amatha kupereka malingaliro othandizira kuthandizira.

Mtengo wa Taltz

Monga mankhwala onse, mtengo wa Taltz umasiyana. Kuti mupeze mitengo yamtundu wa Taltz mdera lanu, onani WellRx.com. Mtengo womwe mumapeza pa WellRx.com ndiomwe mungalipire popanda inshuwaransi. Mtengo weniweni womwe mudzalipira umadalira dongosolo la inshuwaransi yanu, komwe mumakhala, komanso malo ogulitsira mankhwala omwe mumagwiritsa ntchito.

Thandizo lazachuma komanso inshuwaransi

Ngati mukufuna thandizo lazachuma kuti mulipire Taltz, kapena ngati mukufuna thandizo kuti mumvetsetse inshuwaransi yanu, thandizo lilipo.

A Eli Lilly ndi Company, omwe amapanga Taltz, amapereka khadi yosunga ndi pulogalamu yothandizira yotchedwa Taltz Together. Kuti mumve zambiri komanso kuti mudziwe ngati mukuyenera kuthandizidwa, imbani 844-825-8966 kapena pitani patsamba lino.

Taltz amagwiritsa ntchito

Food and Drug Administration (FDA) imavomereza mankhwala akuchipatala monga Taltz kuti athetse mavuto ena. Taltz itha kugwiritsidwanso ntchito polemba zina pazinthu zina. Kugwiritsa ntchito mankhwala osokoneza bongo ndi pamene mankhwala omwe amavomerezedwa kuti athetse vuto limodzi amagwiritsidwa ntchito kuthana ndi vuto lina.

Taltz yamatenda a psoriatic

Taltz ndivomerezedwa ndi FDA kuti athetse matenda a psoriatic nyamakazi mwa akulu.

Matenda a Psoriatic ndi mtundu wa nyamakazi momwe gawo limodzi kapena angapo amatupa, kupweteka, ndi kuuma. Vutoli limayamba pafupifupi 30% ya anthu omwe ali ndi psoriasis. Ndikothekanso kukhala ndi psoriatic nyamakazi musanakhale ndi psoriasis pakhungu lanu.

Matenda a Psoriatic nthawi zambiri amakhudza ziwalo zanu:

  • zala
  • zala zakumiyendo
  • mawondo
  • akakolo
  • manja
  • kutsikira kumbuyo

Taltz amachepetsa kutupa (kutupa) ndi kupweteka m'malo anu. Mankhwalawa amathanso kukuthandizani kuti musamavutike kuyenda komanso kuchita ntchito za tsiku ndi tsiku, monga kuvala, kuchapa, kudya, ndi kuyenda.

Kuchita bwino kwa nyamakazi ya psoriatic

Kafukufuku wamankhwala adayang'ana momwe Taltz adakhudzira zizindikiritso zamatenda a psoriatic. Ofufuzawo adazindikira momwe anthu amapwetekera komanso momwe amaliza ntchito zawo za tsiku ndi tsiku. Ofufuzawo aweruzanso kuchuluka kwa malo olumikizana ndi anthu omwe anali ofewa kapena otupa.

Pambuyo pa masabata 24, Taltz adasintha izi mwa:

  • osachepera 20% mwa 53% mpaka 58% ya anthu
  • osachepera 50% mwa 35% mpaka 40% ya anthu
  • osachepera 70% mu 22% mpaka 23% ya anthu

Taltz ya psoriasis yolimbitsa thupi kwambiri

Taltz ndivomerezedwa ndi FDA kuti ichiritse psoriasis yolimbitsa thupi kwa akulu ndi ana azaka 6 kapena kupitilira apo. Ndi oyenera kwa anthu omwe psoriasis yawo ingapindule ndi mankhwala amachitidwe (mankhwala omwe amakhudza thupi lanu lonse) kapena phototherapy (mankhwala opepuka).

Plaque psoriasis ndiye mtundu wofala kwambiri wa psoriasis. Amatha kukhala ofatsa mpaka owopsa. Dokotala wanu angakuuzeni momwe psoriasis yanu ilili yovuta komanso ngati Taltz ili yoyenera kwa inu. Psoriasis yanu itha kukhala yoyenera kulandira chithandizo ndi Taltz ngati:

  • muli ndi zikwangwani (zakuda, zofiyira, zotupa) pamatupi 3% amthupi lanu
  • muli ndi zikwangwani m'manja, pamapazi, kapena kumaliseche
  • psoriasis yanu imakhudza kwambiri moyo wanu
  • mankhwala omwe ndi apakhungu (ogwiritsidwa ntchito pakhungu lanu) sanabweretse psoriasis yanu

Taltz imathandizira kuchepetsa kuchuluka kwa zikopa za psoriasis komanso momwe zilili zovuta.

Kuchita bwino kwa plaque psoriasis mwa akulu

Kafukufuku wamankhwala adayang'ana momwe Taltz idakhudzira zizindikilo za plaque psoriasis mwa akulu azaka 18 kapena kupitilira apo. Pambuyo pa masabata 12, Taltz adakhazikitsa zizindikiro ndi:

  • osachepera 75% mwa 87% mpaka 90% ya anthu
  • osachepera 90% mu 68% mpaka 71% ya anthu
  • 100% mwa 35% mpaka 40% ya anthu

Ofufuzawo adawunikiranso momwe Taltz imagwirira ntchito mwa anthu omwe zisonyezo zawo za psoriasis zidatha, kapena anali ochepa, pambuyo pa masabata a 12 achipatala. Pambuyo pa masabata 60 atatenga Taltz, 75% mwa anthuwa adakali ndi zisonyezo zochepa za psoriasis.

Ndipo pofufuza zamankhwala a psital maliseche, 73% ya anthu omwe adalandira Taltz anali ndi zizindikilo zochepa chabe kapena anali ndi ziwonetsero pambuyo pa masabata 12.

Kuchita bwino kwa plaque psoriasis mwa ana

Kafukufuku wamankhwala adawona momwe Taltz idakhudzira zizindikilo za plaque psoriasis mwa ana azaka 6 mpaka 18 zakubadwa. Pambuyo pa masabata 12, Taltz adakhazikitsa zizindikiro ndi:

  • osachepera 75% mwa 89% ya ana
  • osachepera 90% mwa 78% ya ana
  • 100% mwa ana 50%

Taltz ya spondyloarthritis

Taltz amavomerezedwa ndi FDA kuti athetse mitundu iwiri ya spondyloarthritis (SA) mwa akulu. Makamaka, Taltz imavomerezedwa kuthana ndi mitundu iwiri yotsatirayi ya SA, yomwe yafotokozedwa mwatsatanetsatane pansipa:

  • non-radiographic axial spondyloarthritis (nr-axSpA)
  • ankylosing spondylitis (AS) kapena radiographic axial spondyloarthritis (r-axSpA)

SA ndi matenda otupa komanso mtundu wa nyamakazi womwe umayambitsa kutupa msana. Kawirikawiri, ziwalo zapafupi zimakhudzidwa, makamaka ziwalo ziwiri zomwe zimagwirizanitsa msana wanu wam'mimba ndi mafupa anu (sacropelvic joints). Pamene kuwonongeka kwa malo sikukuwoneka pa X-ray (radiographs), mawonekedwe a SA amatchedwa nr-axSpA.

SA ikamapita, kutupa kwakanthawi (kwakanthawi) kumatha kupangitsa kuti msana wanu ugwere limodzi. Zotsatira zake, msana wanu umasinthasintha. Kupweteka kumbuyo ndi kutopa ndizizindikiro za SA zomwe zapita patsogolo. Ndi mtundu uwu wa SA, kuwonongeka kwamalumikizidwe kumawoneka pama X-ray. Fomu iyi ya SA imatchedwa yogwira AS, kapena r-axSpA.

Kuchita bwino kwa non-radiographic axial spondyloarthritis

Kafukufuku wamankhwala adayang'ana achikulire azaka 18 kapena kupitilira ndi nr-axSpA. Kafukufukuyu adayang'ana chithandizo ndi Taltz poyerekeza ndi cha placebo (chithandizo chopanda mankhwala ogwiritsira ntchito).

Pambuyo pa chithandizo cha milungu 52:

  • Anthu 30% omwe amagwiritsa ntchito Taltz adachepetsedwa ndi 40% kapena kupitilira apo. Zizindikirozi zimaphatikizapo kuuma m'malo awo ndi msana.
  • Poyerekeza, 13% ya anthu omwe amagwiritsa ntchito malowa anali ndi zotsatira zofananira.

Kuchita bwino kwa ankylosing spondylitis

Kafukufuku awiri azachipatala adayang'ana achikulire azaka 18 kapena kupitilira apo ndi AS yogwira. Maphunzirowa adayang'ana chithandizo ndi Taltz poyerekeza ndi placebo.

Pambuyo pa masabata 16 akuthandizidwa:

  • 25% mpaka 48% ya anthu ogwiritsa ntchito Taltz adachepetsedwa ndi 40% kapena kupitilira apo. Zizindikirozi zimaphatikizapo kuuma m'malo awo ndi msana.
  • Poyerekeza, 13% mpaka 18% ya anthu omwe amagwiritsa ntchito malowa anali ndi zotsatira zofananira.

Kuphatikiza apo, anthu omwe adatenga Taltz anali ndi ululu wochepa ndipo amamva bwino poyerekeza ndi anthu omwe adatenga malowa.

Taltz ndi ana

Taltz amavomerezedwa ndi FDA kuti athetse plaque psoriasis mwa ana azaka 6 kapena kupitilira apo. Kuti mumve zambiri za izi, onani gawo lomwe lili pamwambapa lotchedwa "Taltz ya psoriasis yolimbitsa thupi kwambiri."

Taltz pazinthu zina

Kuphatikiza pazomwe zatchulidwa pamwambapa, Taltz itha kugwiritsidwa ntchito polemba zina. Kugwiritsa ntchito mankhwala osokoneza bongo ndi pamene mankhwala omwe amavomerezedwa kuti agwiritsidwe ntchito kamodzi amagwiritsidwa ntchito mosiyana ndi omwe savomerezedwa. Ndipo mwina mungadabwe ngati Taltz imagwiritsidwa ntchito pazinthu zina.

Taltz wa nyamakazi (kugwiritsa ntchito zilembo)

Taltz sivomerezedwa kuti ichiritse nyamakazi (RA). Komabe, dokotala wanu angakupatseni mankhwalawo ngati mankhwala ena ovomerezeka sakukuthandizani.

RA ndimatenda momwe chitetezo chamthupi chanu chimagwetsera mapfundo anu, kuwapangitsa kutupa, kuuma, komanso kupweteka. Kafukufuku angapo adawona ngati Taltz ingathandize kuthandizira RA. Taltz imagwira ntchito mbali ina ya chitetezo cha mthupi chomwe chimadziwika kuti chimayambitsa ena mwa olumikizana awa (kutupa).

Kuwunikanso kwamaphunziro kunatsimikizira kuti Taltz inali yothandiza pochiza RA.

Ngati mukufuna kudziwa zambiri za kugwiritsa ntchito Taltz kuchiza RA, lankhulani ndi dokotala wanu.

Taltz ya osteoarthritis (osagwiritsa ntchito moyenera)

Taltz sivomerezeka kapena kugwiritsidwa ntchito ngati mankhwala osachiritsika a mafupa. Matenda a nyamakazi amayamba chifukwa cha kufooka kwa mafupa anu. Sizimayambika chifukwa cha kutupa. Chifukwa chake osteoarthritis sichingathandizidwe ndi mankhwala, monga Taltz, omwe amakhudza chitetezo chamthupi.

Ngati muli ndi mafunso okhudza chithandizo chamankhwala a nyamakazi, lankhulani ndi dokotala wanu.

Taltz ndi mowa

Mowa samakhudza mwachindunji momwe Taltz imagwirira ntchito, chifukwa chake palibe machenjezo apadera okhudzana ndi kupewa mowa panthawi ya chithandizo cha Taltz.

Komabe, kumwa mowa kumatha kukulitsa psoriasis, yomwe Taltz amagwiritsidwa ntchito pochiza.Kuphatikiza apo, mowa ungapangitse kuti mankhwala a psoriasis asamagwire bwino ntchito komanso amathanso kupangitsa kuti chitetezo chamthupi chanu chizitha kulimbana ndi matenda.

Malangizo apano pakuthandizira ndikuwongolera psoriasis amalimbikitsa kuchepetsa kuchuluka kwa zakumwa zomwe mumamwa.

Ngati mumamwa mowa, funsani dokotala wanu kuti ndiwotani momwe mungamwe mukamamwa Taltz.

Njira zina ku Taltz

Mankhwala ena alipo omwe angathetse vuto lanu. Ena akhoza kukuyenererani kuposa ena. Ngati mukufuna kupeza njira ina m'malo mwa Taltz, lankhulani ndi dokotala wanu. Amatha kukuwuzani zamankhwala ena omwe atha kukuthandizani.

Zindikirani: Mankhwala ena omwe atchulidwa pano amagwiritsidwa ntchito ngati zilembo kuti athetse vutoli.

Njira zina zamatenda a psoriatic

Zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito pochiza nyamakazi ya psoriatic ndi awa:

  • methotrexate (Otrexup, Rasuvo, Trexall)
  • chifuwa chachikulu (Otezla)
  • infliximab (Kutulutsa)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • alirazamalik (Alirazamalik)
  • golimumab (Simponi)
  • chitsimikizo (Cimzia)
  • secukinumab (Cosentyx)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • sulfasalazine (Azulfidine)

Zindikirani: Kuti mudziwe zambiri zamatenda a psoriatic, onani gawo la "Taltz uses" pamwambapa.

Njira zina zochiritsira zolembapo za psoriasis

Zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito pochizira psoriasis yolemera kwambiri ndi monga:

  • chifuwa chachikulu (Otezla)
  • infliximab (Kutulutsa)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • chitsimikizo (Cimzia)
  • ustekinumab (Stelara)
  • secukinumab (Cosentyx)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • golimumab (Simponi)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Zindikirani: Kuti mudziwe zambiri za plaque psoriasis, onani gawo la "Taltz ntchito" pamwambapa.

Njira zina za ankylosing spondylitis

Zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito pochizira ankylosing spondylitis (AS) ndi awa:

  • infliximab (Kutulutsa)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • secukinumab (Cosentyx)
  • chitsimikizo (Cimzia)
  • golimumab (Simponi)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Zindikirani: Kuti mudziwe zambiri za AS, onani gawo la "Taltz ntchito" pamwambapa.

Njira zina zopanda radiographic axial spondyloarthritis

Zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito pochiza non-radiographic axial spondyloarthritis (nr-axSpA) ndi awa:

  • chitsimikizo (Cimzia)
  • adalimumab (Humira)
  • secukinumab (Cosentyx)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Zindikirani: Kuti mudziwe zambiri za nr-axSpA, onani gawo la "Taltz uses" pamwambapa.

Taltz vs. Cosentyx

Mutha kudabwa momwe Taltz amafanizira ndi mankhwala ena omwe amaperekedwa kuti agwiritse ntchito chimodzimodzi. Apa tikuwona momwe Taltz ndi Cosentyx alili ofanana komanso osiyana.

Pafupi

Taltz ndi Cosentyx onse ndi mankhwala a biologic (mankhwala opangidwa kuchokera kuzinthu zamoyo). Amagwira ntchito yolimbana ndi gawo linalake lamthupi lanu.

Taltz ili ndi mankhwala ixekizumab, pomwe Cosentyx imakhala ndi mankhwalawo secukinumab. Mankhwala awiriwa amatchedwa ma monoclonal antibodies. Amaletsa ntchito ya protein m'thupi lanu yotchedwa interleukin-17. Interleukin-17 imapangitsa kuti chitetezo chamthupi chanu chiwonongeke khungu ndi malo anu. Izi zimayambitsa kutupa komwe kumawoneka ndi matenda monga plaque psoriasis, psoriatic arthritis, ndi spondyloarthritis.

Ntchito

Food and Drug Administration (FDA) yavomereza onse Taltz ndi Cosentyx kuti azichiritsa psoriasis yolimbitsa thupi kwambiri. Mankhwalawa ndi abwino kwa anthu omwe psoriasis yawo imatha kupindula ndi mankhwala amachitidwe (mankhwala omwe amakhudza thupi lanu lonse) kapena phototherapy (mankhwala opepuka).

Kwa plaque psoriasis, Taltz imavomerezedwa kuti igwiritsidwe ntchito kwa akulu ndi ana azaka 6 kapena kupitilira apo. Komabe, Cosentyx imavomerezedwa kuti igwiritsidwe ntchito kwa akulu omwe ali ndi vutoli.

Onse awiri a Taltz ndi Cosentyx nawonso ndi ovomerezeka ndi FDA kuti athetse vuto la nyamakazi mwa psoriatic mwa akulu. ("Wogwira ntchito" amatanthauza kuti pakadali pano muli ndi zizindikiro.)

Kuphatikiza apo, onse a Taltz ndi Cosentyx amavomerezedwa pochiza non-radiographic axial spondyloarthritis ndi yogwira ankylosing spondylitis mwa akulu.

Zindikirani: Kuti mumve zambiri pazomwe zatchulidwazi, onani gawo la "Taltz uses" pamwambapa.

Mafomu azamankhwala ndi makonzedwe

Taltz ndi Cosentyx onse amaperekedwa ndi jakisoni pansi pa khungu lanu (jakisoni wocheperako). Wothandizira zaumoyo wanu amakupatsani jakisoni poyamba. Kenako atha kukuphunzitsani momwe mungadziperekere jakisoni kunyumba.

Taltz imabwera m'njira ziwiri: syringe yogwiritsa ntchito kamodzi komanso cholembera chogwiritsa ntchito kamodzi.

Cosentyx imabwera m'njira zitatu:

  • cholembera chimodzi chogwiritsa ntchito Sensoready
  • syringe yogwiritsira ntchito kamodzi
  • botolo logwiritsira ntchito kamodzi lomwe limaperekedwa ngati jakisoni ndi wothandizira zaumoyo wanu

Zotsatira zoyipa ndi zoopsa

Taltz ndi Cosentyx zitha kuyambitsa zovuta zina zofananira komanso zina. M'munsimu muli zitsanzo za zotsatirazi.

Zotsatira zofala kwambiri

Mndandandawu muli zitsanzo za zovuta zoyipa zomwe zimatha kuchitika ndi Taltz, ndi Cosentyx, kapena ndi mankhwala onse (akamwedwa payekhapayekha).

  • Zitha kuchitika ndi Taltz:
    • zochita za jakisoni (kufiira ndi kuwawa mozungulira jekeseni)
    • conjunctivitis (diso la pinki)
  • Zitha kuchitika ndi Cosentyx:
    • kutsegula m'mimba
    • zilonda mkamwa
    • zotupa pakhungu
  • Zitha kuchitika ndi Taltz ndi Cosentyx:
    • matenda a mafangasi, monga phazi la wothamanga
    • matenda opatsirana apamwamba, monga chimfine
    • nseru

Zotsatira zoyipa

Mndandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Taltz ndi Cosentyx (zikagwidwa payekha).

  • chiopsezo chowonjezeka cha matenda omwe angakhale oopsa, monga chifuwa chachikulu (TB)
  • matenda atsopano kapena owopsa otupa (IBD), monga matenda a Crohn kapena ulcerative colitis
  • aakulu thupi lawo siligwirizana

Kuchita bwino

Taltz ndi Cosentyx ali ndi mitundu yosiyanasiyana yovomerezeka ndi FDA, koma onse amagwiritsidwa ntchito pochita izi:

  • psoriasis yolimbitsa thupi kwambiri
  • psoriatic nyamakazi yomwe ikugwira ntchito (yomwe ikuwonetsa zizindikiro)
  • non-radiographic axial spondyloarthritis
  • yogwira ankylosing spondylitis

Mankhwalawa sanafanane mwachindunji m'maphunziro azachipatala. Komabe, kuwunikanso kumodzi kwa kafukufuku wa plaque psoriasis kunapeza kuti Taltz inali yothandiza kwambiri kuposa Cosentyx pochepetsa zizindikiro za psoriasis.

Maupangiri azachipatala ochokera ku 2018 ndi 2019 amalimbikitsa mankhwala onsewa ngati zosankha kwa anthu omwe amafunikira chithandizo chamankhwala a psoriasis kapena psoriatic arthritis. Biologics ndi mtundu wa mankhwala omwe amalimbana ndi chitetezo chamthupi chanu chomwe chimagwira psoriasis ndi psoriatic nyamakazi.

Dokotala wanu angakulimbikitseni za biologic ngati mankhwala ena sanagwire bwino ntchito. Mwachitsanzo, biologic ikhoza kukhala yoyenera kwa inu ngati:

  • muli ndi psoriasis ya plaque ndipo mankhwala opepuka kapena mankhwala ogwiritsidwa ntchito pakhungu lanu sanagwire ntchito
  • muli ndi nyamakazi ya psoriatic ndi mankhwala oletsa kutupa (omwe amathandiza kuchepetsa kutupa) monga kupweteka kapena ma steroids sikugwira ntchito

Cosentyx ikhoza kukhala yabwinoko kuposa Taltz ya plaque psoriasis yomwe imakhudza misomali. Taltz ikhoza kukhala njira yabwinobwino ya erythrodermic psoriasis, mtundu wosowa kwambiri wa psoriasis.

Mtengo

Taltz ndi Cosentyx onse ndi mankhwala osokoneza bongo. Pakadali pano palibe mitundu yabwinobwino ya mankhwalawa. Mankhwala omwe ali ndi dzina nthawi zambiri amawononga ndalama zambiri kuposa ma generic.

Malinga ndi kuyerekezera kwa WellRx.com, Taltz ndi Cosentyx nthawi zambiri amawononga chimodzimodzi. Mtengo weniweni womwe mudzalipire mankhwalawa umadalira dongosolo lanu la inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Taltz vs. Humira

Kuphatikiza pa Cosentyx (pamwambapa), Humira ndi mankhwala ena omwe amagwiritsa ntchito ena ofanana ndi a Taltz. Apa tikuwona momwe Taltz ndi Humira alili ofanana komanso osiyana.

Pafupi

Taltz ndi Humira onse ndi mankhwala a biologic (mankhwala opangidwa kuchokera kuzinthu zamoyo). Onsewa amagwira ntchito potengera mbali zosiyanasiyana za chitetezo cha mthupi.

Taltz ili ndi ixekizumab, womwe ndi mtundu wa mankhwala otchedwa monoclonal antibody. Imaletsa ntchito ya mapuloteni m'thupi lotchedwa interleukin-17. Interleukin-17 imapangitsa kuti chitetezo cha mthupi chiwononge maselo a pakhungu ndi malo. Izi zimapangitsa kutupa komwe kumawoneka ndi matenda monga plaque psoriasis, psoriatic arthritis, ndi spondyloarthritis.

Humira ali ndi adalimumab, womwe ndi mtundu wa mankhwala omwe amatchedwa block necrosis factor-alpha (TNF-α) blocker. Imaletsa ntchito ya mapuloteni otchedwa TNF-α. Puloteni iyi imathandizira kuyambitsa kutupa m'malo osiyanasiyana, kuphatikiza psoriasis ndi psoriatic nyamakazi.

Ntchito

Food and Drug Administration (FDA) yavomereza onse a Taltz ndi Humira kuti azichiza psoriasis yolemera kwambiri. Dokotala wanu akhoza kukupatsani imodzi mwa mankhwalawa ngati psoriasis yanu ingapindule ndi chithandizo chamankhwala (mankhwala omwe amakhudza thupi lanu lonse) kapena phototherapy (mankhwala opepuka).

Kwa plaque psoriasis, Taltz imavomerezedwa kuti igwiritsidwe ntchito kwa akulu ndi ana azaka 6 kapena kupitilira apo. Komabe, Humira imangovomerezedwa kuti igwiritsidwe ntchito kwa akulu omwe ali ndi vutoli.

Onse awiri a Taltz ndi Humira nawonso ndi ovomerezeka ndi FDA kuti athetse matenda a nyamakazi mwa akulu. ("Wogwira ntchito" amatanthauza kuti pakadali pano muli ndi zizindikiro.)

Kuphatikiza apo, onse a Taltz ndi Humira amaloledwa kuchiza ankylosing spondylitis mwa akulu. Koma ndi Taltz yokhayo yomwe imavomerezeka pochiza anthu osachita radiographic axial spondyloarthritis.

Humira alinso ndi chilolezo ku FDA pochiza izi:

  • nyamakazi (RA)
  • nyamakazi yaunyamata yoopsa kwambiri
  • Matenda a Crohn
  • zolimbitsa mpaka kwambiri zilonda zam'mimba
  • hidradenitis suppurativa, khungu lopweteka lomwe limatchedwanso acne inversa
  • mitundu ina ya noninfectious uveitis (mtundu wa kutupa kwa diso), kuphatikiza pakati uveitis, posterior uveitis, ndi panuveitis

Zindikirani: Kuti mudziwe zambiri za momwe Taltz imavomerezedwera, onani gawo la "Taltz limagwiritsa ntchito" pamwambapa.

Mafomu azamankhwala ndi makonzedwe

Taltz ndi Humira onse amaperekedwa ndi jakisoni pansi pa khungu lanu (jakisoni wocheperako). Wothandizira zaumoyo wanu amakupatsani jakisoni poyamba. Kenako atha kukuphunzitsani momwe mungadziperekere jakisoni kunyumba.

Taltz imabwera m'njira ziwiri: syringe yogwiritsa ntchito kamodzi komanso cholembera chogwiritsa ntchito kamodzi.

Humira amabwera m'njira zitatu:

  • cholembera chogwiritsa ntchito kamodzi
  • syringe yogwiritsira ntchito kamodzi
  • botolo logwiritsira ntchito kamodzi lomwe limaperekedwa ngati jakisoni ndi wothandizira zaumoyo wanu

Zotsatira zoyipa ndi zoopsa

Taltz ndi Humira atha kubweretsanso zovuta zina zina. M'munsimu muli zitsanzo za zotsatirazi.

Zotsatira zofala kwambiri

Mndandandawu muli zitsanzo za zovuta zoyipa zomwe zimatha kuchitika ndi Taltz, ndi Humira, kapena ndi mankhwala onsewa (akatengedwa payekhapayekha).

  • Zitha kuchitika ndi Taltz:
    • Matenda a fungus, monga phazi la wothamanga
    • conjunctivitis (diso la pinki)
  • Zitha kuchitika ndi Humira:
    • kupweteka mutu
    • zidzolo
  • Zitha kuchitika ndi Taltz ndi Humira:
    • zochita za jakisoni, monga kufiira ndi kuwawa kozungulira jekeseni
    • matenda opatsirana apamwamba, monga chimfine
    • nseru

Zotsatira zoyipa

Mndandandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Taltz, ndi Humira, kapena ndi mankhwala onsewa (akamwedwa payekhapayekha).

  • Zitha kuchitika ndi Taltz:
    • matenda atsopano kapena owopsa otupa (IBD), monga matenda a Crohn kapena ulcerative colitis
  • Zitha kuchitika ndi Humira:
    • mavuto a chiwindi, monga kulephera kwa chiwindi
    • mavuto amanjenje, monga multiple sclerosis (MS)
    • mavuto amwazi, monga kuchepa kwama cell ofiira ofiira, maselo oyera, kapena ma platelets
    • kulephera kwa mtima
    • mafangasi matenda, monga histoplasmosis
    • chiopsezo chowonjezeka cha khansa zina, monga khansa yapakhungu, leukemia, ndi lymphoma
    • psoriasis yatsopano kapena yowonjezereka
  • Zitha kuchitika ndi Taltz ndi Humira:
    • chiopsezo chowonjezeka cha matenda omwe angakhale oopsa, monga chifuwa chachikulu (TB)
    • aakulu thupi lawo siligwirizana

Kuchita bwino

Taltz ndi Humira ali ndi ntchito zosiyanasiyana zovomerezeka ndi FDA, koma zonse zimagwiritsidwa ntchito pochita izi:

  • psoriasis yolimbitsa thupi kwambiri
  • nyamakazi ya psoriatic yogwira
  • yogwira ankylosing spondylitis

Mankhwalawa sanayerekezeredwe mwachindunji mwa anthu omwe ali ndi plaque psoriasis, koma kafukufuku wapeza kuti Taltz ndi Humira ali othandiza kuthana ndi vutoli.

Kafukufuku wina wamankhwala adayang'ana onse a Taltz ndi Humira mwa anthu omwe ali ndi nyamakazi ya psoriatic. Pambuyo pa masabata 24, matenda a psoriatic nyamakazi adachepetsedwa ndi 20% mwa 58% mpaka 62% ya anthu omwe adatenga Taltz. Izi zikuyerekeza ndi 57% ya anthu omwe adatenga Humira ndi 30% omwe adatenga placebo (palibe chithandizo).

Maupangiri azachipatala ochokera ku 2018 ndi 2019 amalimbikitsa mankhwala onsewa ngati njira kwa anthu omwe amafunikira chithandizo cha biologic cha psoriasis kapena psoriatic nyamakazi. Biologics ndi mtundu wa mankhwala omwe amalimbana ndi chitetezo chamthupi chanu chomwe chimagwira psoriasis ndi psoriatic nyamakazi.

Dokotala wanu angakulimbikitseni za biologic ngati mankhwala ena sanagwire bwino ntchito. Mwachitsanzo, biologic ikhoza kukhala yoyenera kwa inu ngati:

  • muli ndi psoriasis ya plaque ndipo mankhwala opepuka kapena mankhwala opakidwa pakhungu lanu sanagwire ntchito
  • muli ndi nyamakazi ya psoriatic ndi mankhwala oletsa kutupa (omwe amathandiza kuchepetsa kutupa) monga kupweteka kapena ma steroids sikugwira ntchito

Kwa anthu ambiri omwe akuyamba mankhwala a psoriatic arthritis, malangizo a 2018 amalimbikitsa kugwiritsa ntchito TNF-alpha blockers (monga Humira) pa interleukin-17 blockers (monga Taltz). Malangizo a 2019 akuti Humira amathanso kukhala abwinoko kuposa Taltz ya plaque psoriasis yomwe imakhudza khungu ndi erythrodermic psoriasis (mtundu wosowa kwambiri wa psoriasis).

Kafukufuku wamankhwala adayerekezera momwe Taltz ndi Humira aliri othandizira pochiza nyamakazi ya psoriatic ndi plaque psoriasis. Kafukufukuyu adawonetsa kuti pamasabata 24 a chithandizo, anthu 36% omwe adatenga Taltz adakhala ndi zisonyezo zosachepera 50%. Poyerekeza, anthu 28% omwe adatenga Humira adakhala ndi zisonyezo zosachepera 50%.

Mtengo

Taltz ndi Humira onse ndi mankhwala osokoneza bongo. Pakadali pano palibe mitundu yabwinobwino ya mankhwalawa. Mankhwala omwe ali ndi dzina nthawi zambiri amawononga ndalama zambiri kuposa ma generic.

Malinga ndi kuyerekezera kwa WellRx.com, Taltz ndi Humira nthawi zambiri amawononga chimodzimodzi. Mtengo weniweni womwe mudzalipire mankhwalawa umadalira dongosolo lanu la inshuwaransi, komwe mumakhala, komanso mankhwala omwe mumagwiritsa ntchito.

Kuyanjana kwa Taltz

Taltz amatha kuyanjana ndi mankhwala ena. Kuyanjana kosiyanasiyana kumatha kubweretsa zovuta zosiyanasiyana. Mwachitsanzo, kulumikizana kwina kumatha kusokoneza momwe mankhwala amagwirira ntchito. Kuyanjana kwina kumatha kukulitsa zovuta zina kapena kuwapangitsa kukhala owopsa.

Taltz ndi mankhwala ena

M'munsimu muli mndandanda wa mankhwala omwe angagwirizane ndi Taltz. Mndandandawu mulibe mankhwala onse omwe amatha kulumikizana ndi Taltz.

Musanatenge Taltz, lankhulani ndi dokotala komanso wamankhwala. Auzeni zamankhwala onse omwe mumalandira, pa-pakauntala, ndi mankhwala ena omwe mumamwa. Auzeni za mavitamini, zitsamba, ndi zowonjezera zilizonse zomwe mumagwiritsa ntchito. Kugawana izi kungakuthandizeni kupewa kuyanjana komwe kungachitike.

Ngati muli ndi mafunso okhudzana ndi mankhwala omwe angakukhudzeni, funsani dokotala kapena wamankhwala.

Taltz ndi warfarin

Warfarin (Coumadin, Jantoven) ndi mtundu wamagazi owonda, mankhwala omwe amathandiza kupewa magazi. Kutenga Taltz ndi warfarin kumapangitsa kuti warfarin yanu isamagwire bwino ntchito.

Ngati mukumwa warfarin, dokotala wanu angafune kuwunika kuti magazi anu amatenga nthawi yayitali bwanji mutayamba Taltz, mukamamwa mankhwala, komanso ngati mwaletsa Taltz. Amatha kusintha mlingo wanu wa warfarin ngati kuli kofunikira.

Taltz ndi cyclosporine

Cyclosporine ndi mankhwala osokoneza bongo. Mumazitenga kuti muchepetse ntchito yoteteza thupi lanu. Kutenga Taltz ndi cyclosporine kungapangitse kuti cyclosporine yanu ikhale yopanda ntchito.

Ngati mukumwa cyclosporine, dokotala wanu angafune kuti muone kuchuluka kwa mankhwalawo m'magazi anu mutayamba Taltz, mukamamwa mankhwala komanso ngati mwalepheretsa Taltz. Amatha kusintha mlingo wa cyclosporine ngati kuli kofunikira.

Cyclosporine imapezekanso ngati mankhwala otsatirawa:

  • Cequa
  • Gengraf
  • Zosowa
  • Kubwezeretsa
  • Sandimmune

Taltz ndikukhala ndi katemera

Kupeza katemera wamoyo pomwe mukumwa Taltz kumatha kuyambitsa matenda akulu.

Katemera wamoyo ali ndi mitundu yofooka ya mavairasi kapena mabakiteriya, koma samayambitsa matenda mwa anthu omwe ali ndi chitetezo chamthupi chokwanira. Komabe, katemera wamoyo amatha kuyambitsa matenda mwa anthu omwe chitetezo chamthupi chawo chimakhudzidwa ndi chithandizo cha Taltz.

Pamene mukumwa Taltz, simuyenera kulandira katemera wamoyo monga:

  • nthomba
  • yellow fever
  • chifuwa chachikulu (TB)
  • chikuku, chikuku, ndi rubella (MMR)

Ndibwino kupeza katemera wosagwira (osakhala amoyo), monga chimfine, mukamalandira chithandizo ku Taltz. Komabe, katemera wosagwira ntchito mwina sangagwire ntchito monga momwe amathandizira. (Katemera amagwira ntchito poyambitsa chitetezo chamthupi chanu kutulutsa ma antibodies omwe amathandiza kulimbana ndi matenda. Taltz imatha kupangitsa kuti chitetezo chamthupi chanu chisamathe kupanga ma antibodies.)

Ngati dokotala akufuna kuti mutenge Taltz, funsani ngati mukudziwa bwino za katemera wovomerezeka.

Taltz ndi zitsamba ndi zowonjezera

Palibe zitsamba zilizonse kapena zowonjezera zomwe zanenedwa kuti zimalumikizana ndi Taltz. Koma onetsetsani kuti mufunsane ndi wamankhwala musanagwiritse ntchito iliyonse.

Momwe mungatengere Taltz

Mankhwalawa amaperekedwa ndi jakisoni pansi pa khungu lanu (jakisoni wamagetsi). Wothandizira zaumoyo wanu amakupatsani jakisoni poyamba. Kenako atha kukuphunzitsani momwe mungadziperekere jakisoni kunyumba. Mutha kutenga jakisoni wanu wa Taltz nthawi iliyonse patsiku patsikuli.

Taltz imabwera ngati jakisoni woyambira limodzi komanso ngati cholembera chogwiritsa ntchito kamodzi. Funsani dokotala wanu zomwe zili zabwino kwa inu. Mitundu yonseyi imakhala ndi mlingo umodzi. Mumabaya jakisoni wathunthu kenako ndikutaya syringe kapena cholembera chotsitsa.

Nthawi yoti mutenge

Mukafunika kumwa Mlingo wa Taltz zimatengera momwe akuchiritsira. Nthawi zambiri, mudzalandira mlingo wanu woyamba wa Taltz kuofesi ya dokotala wanu. Kenako mudzatha kudzipatsa nokha jakisoni wotsatira.

Pansipa, tikufotokozera magawo amtundu wa Taltz pazogwiritsa ntchito.

  • Ngati muli ndi psoriasis: Pa mlingo wanu woyamba wa Taltz, mudzalandira jakisoni awiri tsiku lomwelo. Pambuyo pa mlingo woyamba wa Taltz, mudzakhala ndi jakisoni mmodzi masabata awiri aliwonse kwa masabata 12. Izi zidzatsatiridwa ndi jakisoni m'masabata 4 aliwonse malinga ndi momwe dokotala akuwalimbikitsira.
  • Ngati muli ndi nyamakazi ya psoriatic: Pa mlingo wanu woyamba wa Taltz, mudzalandira jakisoni awiri tsiku lomwelo. Pambuyo pa mlingo woyamba wa Taltz, mudzakhala ndi jakisoni mmodzi masabata anayi aliwonse malinga ndi momwe dokotala akuwalimbikitsira.
  • Ngati muli ndi psoriasis ndi psoriatic nyamakazi: Mudzalandira Mlingo wa Taltz kutengera ndondomeko yoyeserera ya psoriasis, yomwe yafotokozedwa pamwambapa.
  • Ngati muli ndi non-radiographic axial spondyloarthritis (nr-axSpA): Pambuyo pa mlingo wanu woyamba wa Taltz, mudzakhala ndi jakisoni mmodzi masabata anayi aliwonse.
  • Ngati muli ndi ankylosing spondylitis (AS): Pa mlingo wanu woyamba wa Taltz, mudzalandira jakisoni awiri tsiku lomwelo. Pambuyo pa mlingo woyamba wa Taltz, mudzakhala ndi jakisoni mmodzi masabata anayi aliwonse.

Kuti Taltz izigwire bwino ntchito, ndikofunikira kuzitenga monga adokotala anu akunenera. Kuti mutsimikizire kuti mukukumbukira kumwa mankhwalawa, ndibwino kuti mulembe ndandanda yanu ya jakisoni pakalendala. Muthanso kugwiritsa ntchito chida chokumbutsirani mankhwala kuti musayiwale.

Zindikirani: Kuti mumve zambiri pazomwe zalembedwa pano, onani gawo la "Taltz uses" pamwambapa.

Momwe mungapangire jakisoni

Wopereka chithandizo chamankhwala amakuphunzitsani momwe mungagwiritsire ntchito syringe kapena cholembera chodzipangira. Kuti mumve zambiri, makanema, ndi zithunzi za malangizo a jakisoni, onani tsamba la wopanga.

Kumbukirani kuti malo oyenera kubaya Taltz ali patsogolo pa ntchafu zanu kapena mimba (mimba). Muthanso kugwiritsa ntchito kumbuyo kwa manja anu apamwamba, koma mungafunike wina kuti akupatseni jakisoni.

Momwe Taltz imagwirira ntchito

Psoriasis, psoriatic nyamakazi, ndi spondyloarthritis ndizomwe zimayambitsa matendawa. Zimapangitsa kuti chitetezo chamthupi chanu (chitetezo chamthupi mwanu motsutsana ndi matenda) chiwononge maselo abwinobwino.

Kuti mumve zambiri pazinthu izi, onani gawo la "Taltz uses" pamwambapa.

Mbali zosiyanasiyana za chitetezo cha mthupi zimakhudzidwa ndi izi. Njira imodzi yodziwika ndi yokhudza mapuloteni otchedwa interleukin-17A. Puloteni iyi imauza chitetezo chanu chamthupi kuti chiwononge maselo pakhungu lanu ndi malo anu.

Taltz ili ndi ixekizumab, womwe ndi mtundu wa mankhwala otchedwa humanized monoclonal antibody. Imagwira ntchito pomanga (kuphatikiza) ku interleukin-17A. Pochita izi, Taltz amalepheretsa mapuloteniwo. Zimayimitsa kuti isauze chitetezo chanu chamthupi kuti chiwononge maselo pakhungu lanu ndi malo anu.

Poletsa chitetezo cha mthupi lanu kuti chiwononge maselo, Taltz imathandiza:

  • chepetsani mapangidwe pakhungu lanu pakhungu la psoriasis
  • kuchepetsa kutupa (kutupa) kwa malo anu mu psoriatic nyamakazi, non-radiographic axial spondyloarthritis, ndi yogwira ankylosing spondylitis

Zimatenga nthawi yayitali bwanji kuti zigwire ntchito?

Taltz imayamba kugwira ntchito mukangoyamba kumene mankhwala. Komabe, mwina zingatenge masabata angapo kuti muone kusintha kulikonse.

M'maphunziro azachipatala, anthu ambiri omwe ali ndi plaque psoriasis anali ndi khungu loyera kapena pafupifupi khungu pakatha milungu 12 atayamba mankhwala kapena posachedwa. Ndipo pafupifupi theka la anthu omwe ali ndi nyamakazi ya psoriatic omwe adatenga Taltz anali ndi zizindikilo zochepa komanso magwiridwe antchito pakadutsa milungu 12 kuchokera pomwe mankhwala adayamba.

Kafukufuku wamankhwala achikulire omwe ali ndi non-radiographic axial spondyloarthritis adayang'ana chithandizo ndi Taltz ndi chithandizo chokhala ndi placebo. (A placebo ndi mankhwala opanda mankhwala.) Pambuyo pa chithandizo cha milungu 52, anthu 30% omwe amagwiritsa ntchito Taltz adachepetsa 40%. Poyerekeza, 13% ya anthu omwe amagwiritsa ntchito malowa anali ndi zotsatira zofananira.

Kafukufuku awiri azachipatala omwe ali ndi vuto la ankylosing spondylitis adayang'ana chithandizo ndi Taltz poyerekeza ndi placebo. Pambuyo pa chithandizo cha milungu 16, 25% mpaka 48% ya anthu omwe amagwiritsa ntchito Taltz adachepetsa 40% kapena kupitilira apo. Poyerekeza, 13% mpaka 18% ya anthu omwe amagwiritsa ntchito malowa anali ndi zotsatira zofananira.

Taltz ndi mimba

Taltz sanaphunzirepo mwa amayi apakati, motero sizikudziwika ngati mankhwalawa ndi abwino kumwa panthawi yapakati.

Onetsetsani kuti muuze dokotala ngati muli ndi pakati kapena mukukonzekera kukhala ndi pakati musanayambe mankhwala. Ngati mukuganiza kuti mutha kukhala ndi pakati mukamatenga Taltz, lankhulani ndi dokotala nthawi yomweyo.

Taltz ndi kulera

Sizikudziwika ngati Taltz ndiyabwino kutenga panthawi yapakati. Ngati mukugonana ndipo inu kapena mnzanuyo mutha kutenga pakati, lankhulani ndi dokotala wanu zakufunika kwanu poletsa kugwiritsa ntchito Taltz.

Kuti mumve zambiri za kutenga Taltz mukakhala ndi pakati, onani gawo la "Taltz ndi pakati" pamwambapa.

Taltz ndi kuyamwitsa

Sidziwika ngati Taltz imadutsa mkaka wa m'mawere kapena ngati imakhudza momwe thupi lanu limapangira mkaka wa m'mawere. Taltz anapezeka mu mkaka wa m'mawere mu maphunziro a zinyama, koma maphunziro a nyama samawonetsa nthawi zonse zomwe zidzachitike mwa anthu.

Ngati mukuyamwitsa ndikuganizira zotenga Taltz, lankhulani ndi dokotala wanu. Amatha kukambirana nanu za zoopsa ndi phindu la mankhwalawo.

Mafunso wamba okhudza Taltz

Nawa mayankho pamafunso omwe amafunsidwa kawirikawiri za Taltz.

Kodi Taltz ndi biologic?

Inde. Taltz ndi mankhwala a biologic. Izi zikutanthauza kuti ndi mankhwala opangidwa kuchokera ku mapuloteni osati kuchokera kumankhwala (monga mankhwala ambiri amathandizira). Mankhwala a biologic amapangidwa mu labu pogwiritsa ntchito maselo anyama.

Kodi ndifunikirabe kugwiritsa ntchito mafuta apakhungu a psoriasis ndikugwiritsa ntchito Taltz?

Mwina. Koma muyenera kutsatira malangizo a dokotala pankhaniyi.

Ngati khungu lanu limatha bwino mukamamwa Taltz, ndiye kuti simusowa kuti mupitirize kugwiritsa ntchito mankhwala azitsamba. Koma nthawi zina, mumatha kukhala ndi ma psoriasis (wandiweyani, wofiira, zigamba pakhungu lanu). Izi zikachitika, dokotala wanu angakulimbikitseni kuti mupitilize kugwiritsa ntchito mafuta othandizira kapena mankhwala ena apakhungu momwe mungafunikire. Nthawi zonse tsatirani malangizo omwe dokotala akukupatsani.

Kodi kugwiritsa ntchito Taltz kungayambitse matenda opweteka atsopano?

Inde ikhoza, ngakhale izi ndizochepa. Matenda opatsirana otupa (IBD) ndi gulu la matenda omwe amayambitsa kutupa (kutupa) m'mimba mwanu. Matendawa amaphatikizapo matenda a Crohn's and ulcerative colitis.

M'maphunziro azachipatala, matenda a Crohn adachitika mwa 0,1% mwa anthu omwe ali ndi plaque psoriasis omwe adalandira Taltz. Ulcerative colitis idachitika mwa anthu 0,2% omwe ali ndi plaque psoriasis omwe adalandira Taltz.

Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka za IBD, onani dokotala wanu. Zizindikirozo zimatha kuphatikizira kupweteka m'mimba mwako (m'mimba), kutsegula m'mimba kapena wopanda magazi, komanso kuchepa thupi.

Kodi ndingatani kuti ndipewe matenda ndikamamwa Taltz?

Taltz imatha kufooketsa gawo lina lama chitetezo chamthupi, chifukwa chake mankhwalawa akhoza kukulitsa chiopsezo chotenga matenda. Nawa maupangiri okuthandizani kuteteza chitetezo cha mthupi lanu ndikukuthandizani kupewa matenda:

  • Musanayambe kumwa mankhwala, lankhulani ndi dokotala wanu zakakufotokozerani za katemera aliyense woyenera.
  • Sambani m'manja nthawi zonse, makamaka ngati mwakhala muli pagulu.
  • Yesetsani kupewa kucheza kwambiri ndi anthu omwe ali ndi matenda, makamaka chifuwa, chimfine, kapena chimfine.
  • Pewani kugawana matawulo kapena nsalu ndi aliyense amene ali ndi matenda a fungal kapena zilonda zozizira.
  • Idyani chakudya chopatsa thanzi.
  • Muzigona mokwanira.
  • Osasuta.

Kodi Taltz amachiza plaque psoriasis kapena psoriatic arthritis?

Ayi, Taltz sachiza izi. Pakadali pano palibe mankhwala a plaque psoriasis kapena psoriatic arthritis. Koma chithandizo chanthawi yayitali ndi Taltz chitha kuthandiza kuwongolera zizindikilo za izi.

Kafukufuku wamankhwala adasanthula anthu omwe ali ndi plaque psoriasis omwe adatenga Taltz. Zizindikiro za anthu ena zidachokeratu kapena zidayamba kuchepa patadutsa milungu 12. Theka la gululi lidatenga Taltz kwa masabata ena 48. Hafu ina ya gululo idatenga maloboti (osalandira chithandizo) kwa milungu 48.

Mwa anthu omwe amapitiliza kumwa Taltz, 75% adalibe kapena zochepa pakumaliza kuphunzira. Kwa anthu ambiri omwe adatenga malowa, matendawa adakumananso. Ndi 7% yokha yamagulu a placebo omwe analibe kapena zochepa. Nthawi yayitali yomwe zimatengera kuti matenda achuluke mwa anthu omwe adatenga malowa anali masiku 164. Koma atayambiranso kumwa Taltz, kwa 66% ya anthuwa, psoriasis yawo idatuluka mkati mwa milungu 12.

Zosamalitsa za Taltz

Musanatenge Taltz, lankhulani ndi dokotala za mbiri yanu. Taltz mwina sangakhale yoyenera kwa inu ngati mukudwala. Izi zikuphatikiza:

  • Matenda aliwonse, koma chifuwa chachikulu makamaka. Taltz imapangitsa kuti chitetezo cha m'thupi lanu muchepetse kulimbana ndi majeremusi, chifukwa chake matenda monga chifuwa chachikulu (TB) atha kukhala owopsa.
    • Ngati muli ndi TB kapena mudakhalapo ndi TB m'mbuyomu, mungafunike kumwa mankhwala ochiritsira. TB itachiritsidwa, mutha kuyamba kumwa Taltz.
    • Ngati muli ndi zizindikiro za matenda ena, monga malungo, kapena ngati mukudwala matenda omwe amabwereranso, uzani dokotala wanu. Matendawa angafunikire kuthandizidwa musanayambe mankhwala ndi Taltz.
  • Matenda otupa. Nthawi zambiri, Taltz imatha kukulitsa zizindikiritso zamatenda otupa (IBD). IBD ndi gulu la matenda omwe amaphatikizapo matenda a Crohn ndi ulcerative colitis. Ngati muli ndi IBD, lankhulani ndi dokotala wanu. Amatha kuwunika zomwe mukudwala mukamatenga Taltz. Ngati IBD yanu ikuipiraipira, mungafunikire kuyimitsa Taltz. Palinso mankhwala ena a biologic omwe saipitsa IBD omwe mungayesere.

Zindikirani: Kuti mumve zambiri paza zotsatira zoyipa za Taltz, onani gawo la "Zotsatira za Taltz" pamwambapa.

Bongo Taltz

Sirinji iliyonse yodzaza ndi cholembera ndi autoinjector imakhala ndimlingo wokwanira wa mankhwala pamlingo umodzi. Chifukwa chake kuledzera kumatheka pokhapokha mutadzipatsa jakisoni angapo kapena ngati mumamwa Taltz pafupipafupi.

Zizindikiro zambiri za bongo

Zizindikiro za bongo zingaphatikizepo zovuta zomwe zimachulukirachulukira kapena zowopsa, monga:

  • matenda opatsirana apamwamba, monga chimfine
  • nseru
  • matenda a mafangasi, monga phazi la wothamanga
  • aakulu thupi lawo siligwirizana
  • Matenda otupa (IBD), monga matenda a Crohn kapena ulcerative colitis
  • chiopsezo chowonjezeka cha matenda, monga chifuwa chachikulu (TB)

Zomwe muyenera kuchita mukamagwiritsa ntchito bongo

Ngati mukuganiza kuti mwamwa kwambiri mankhwalawa, itanani dokotala wanu. Muthanso kuyitanitsa American Association of Poison Control Center ku 800-222-1222 kapena kugwiritsa ntchito chida chawo pa intaneti. Koma ngati matenda anu akukulira, itanani 911 kapena pitani kuchipatala chapafupi pomwepo.

Kutha kwa Taltz, kusunga, ndi kutaya

Mukapeza Taltz kuchokera ku pharmacy, wamankhwala adzawonjezera tsiku lotha ntchito pa cholembedwacho. Tsikuli limakhala chaka chimodzi kuyambira tsiku lomwe adapereka mankhwalawo.

Tsiku lothera ntchito limathandizira kutsimikizira kuti mankhwalawa ndi othandiza panthawiyi. Maganizo apano a Food and Drug Administration (FDA) ndikupewa kugwiritsa ntchito mankhwala omwe atha ntchito. Ngati mwagwiritsa ntchito mankhwala omwe sanadutse tsiku lomaliza, funsani wazamankhwala wanu ngati mutha kugwiritsa ntchito.

Yosungirako

Kutalika kwa nthawi yayitali kumadalira mankhwala, kuphatikiza momwe mungasungire mankhwalawo.

Majekeseni oyandikira a Taltz ndi zolembera zama autoinjector ziyenera kusungidwa mufiriji pa 36 ° F mpaka 46 ° F (2 ° C mpaka 8 ° C). Onetsetsani kuti sakupezeka ndi ana. Osazizira Taltz. Ndipo musagwiritse ntchito mankhwalawa ngati achita kuzizira.

Nthawi zina, mungafunike kutenga Taltz mufiriji musanagwiritse ntchito. Mwachitsanzo, ngati mukupita kwa masiku angapo ndipo mufunika jakisoni panthawiyi. Dziwani kuti mutha kusunga Taltz kutentha mpaka 86 ° F (30 ° C) mpaka masiku asanu.

Onetsetsani kuti mukusunga syringe kapena cholembera autoinjector mu katoni yake yoyambirira kuti muteteze ku kuwala. Ngati simugwiritsa ntchito sirinji kapena cholembera pasanathe masiku 5, muyenera kutaya mosamala. Simuyenera kuyika Taltz mufiriji ikasungidwa kutentha.

Kutaya

Mutagwiritsa ntchito sirinji ya Taltz kapena cholembera autoinjector, ikani mu chidebe chovomerezeka chovomerezedwa ndi FDA. Izi zimathandiza kupewa ena, kuphatikiza ana ndi ziweto, kuti amwe mankhwalawo mwangozi. Zimathandizanso kuti mankhwalawa asawononge chilengedwe.

Ngati mulibe chidebe chakuthwa, mutha kugula chimodzi pa intaneti ku pharmacy yakwanuko.

Mutha kupeza malangizo othandizira kuthana ndi mankhwala pano. Muthanso kufunsa wamankhwala wanu kuti akupatseni malangizo amomwe mungathere mankhwala anu.

Zambiri zamaluso za Taltz

Zotsatirazi zimaperekedwa kwa azachipatala ndi ena othandizira azaumoyo.

Zisonyezero

Food and Drug Administration (FDA) yavomereza Taltz kuchiza:

  • zolimbitsa thupi mpaka zolembera zolemera kwambiri za psoriasis zomwe ndi zoyenera kugwiritsa ntchito ma systemic kapena phototherapy; Pogwiritsa ntchito izi, mankhwalawa amatha kuperekedwa kwa akulu ndi ana azaka 6 kapena kupitilira apo
  • nyamakazi yogwira psoriatic mwa akulu
  • non-radiographic axial spondyloarthritis (nr-axSpA) mwa akulu
  • ankylosing spondylitis (AS) yogwira ntchito, yomwe imatchedwanso radiographic axial spondyloarthritis (r-axSpA); pakugwiritsa ntchito izi, mankhwala amatha kuperekedwa kwa achikulire

Njira yogwirira ntchito

Taltz imakhala ndi ixekizumab, yomwe ndi anti-IgG monoclonal antibody. Ixekizumab imasankha ndikumangirira ku interleukin-17A (IL-17A). IL-17A ndi amodzi mwa ma cytokines otupa omwe amadziwika kuti amatenga nawo gawo pakupanga mayankho otupa komanso amthupi omwe amayambitsa matenda a psoriatic ndi ankylosing spondylitis. Pogwirizana ndi IL-17A, ixekizumab imayimitsa kuti isayanjane ndi IL-17A receptor ndipo imalepheretsa mayankhowa.

Pharmacokinetics ndi metabolism

Ixekizumab bioavailability kuyambira 60% mpaka 81% kutsatira jakisoni wocheperako m'maphunziro a psoriasis. Kuchulukanso kwa bioavailability kunakwaniritsidwa kudzera mu jakisoni ntchafu poyerekeza ndi malo ena obayira monga mkono ndi pamimba.

Tanthauzo la theka la moyo anali masiku 13 m'maphunziro omwe anali ndi plaque psoriasis.

Njira yochotsera kagayidwe kachakudya sinadziwike, koma ikuyembekezeka kukhala yofanana ndi ya IgG yodalirika yokhala ndi njira zopangira ma peptide ang'onoang'ono ndi ma amino acid.

Zotsutsana

Taltz imatsutsana ndi anthu omwe ali ndi vuto lalikulu la hypersensitivity reaction, monga anaphylaxis, ku ixekizumab kapena omwe amathandizira.

Yosungirako

Taltz autoinjector ndi syringe yoyikiratu iyenera kusungidwa mufiriji pa 36 ° F mpaka 46 ° F (2 ° C mpaka 8 ° C).

Osazizira. Tetezani ku kuwala. Musagwedezeke. Taltz imatha kusungidwa kutentha mpaka 86 ° F (30 ° C) mpaka masiku asanu. Mukasungidwa kutentha, sikuyenera kuyikidwanso mufiriji.

Chodzikanira: Medical News Today yachita zonse zotheka kuti zitsimikizire kuti chidziwitso chonse ndicholondola, chokwanira, komanso chaposachedwa. Komabe, nkhaniyi sikuyenera kugwiritsidwa ntchito m'malo mwa chidziwitso ndi ukadaulo wa akatswiri pazachipatala. Muyenera kufunsa adotolo kapena akatswiri azaumoyo musanamwe mankhwala aliwonse. Zambiri zamankhwala zomwe zili pano zitha kusintha ndipo sizingapangidwe kuti zigwiritse ntchito, mayendedwe, zodzitetezera, machenjezo, kulumikizana ndi mankhwala, kusokonezeka, kapena zovuta zina. Kusapezeka kwa machenjezo kapena zidziwitso za mankhwala omwe apatsidwa sikuwonetsa kuti kuphatikiza mankhwala kapena mankhwalawa ndiwotetezeka, ogwira ntchito, komanso oyenera kwa odwala onse kapena ntchito zina zilizonse.

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