Chiyeso cha Cholinesterase: ndi chiyani, ndi chiyani komanso zotsatira zake zikutanthauza chiyani

Zamkati

• Ndi chiyani
• Malingaliro owonetsera
• Zomwe zotsatira zake zikutanthauza

Mayeso a cholinesterase ndi mayeso a labotale omwe amafunsidwa kuti atsimikizire kuchuluka kwa munthuyo pazinthu zowopsa, monga mankhwala ophera tizilombo, mankhwala ophera tizilombo, mankhwala ophera tizilombo kapena feteleza, mwachitsanzo, kukhala oyenera kwambiri kwa alimi, chifukwa amalumikizana pafupipafupi ndi mankhwala aulimi.

Cholinesterase ndi enzyme yomwe imakhalapo m'thupi lomwe limayambitsa kuwonongeka kwa chinthu chotchedwa acetylcholine, neurotransmitter yomwe imayang'anira kuwongolera kwa mitsempha ya minofu. Pali magulu awiri a cholinesterase:

• Mpweya wambiri wolinesterase, yomwe imanyamulidwa ndi maselo ofiira ofiira;
• Plasma cholinesterase kapena seramu, yomwe ndi cholinesterase yopangidwa ndi chiwindi, kapamba ndi matumbo ang'onoang'ono komanso omwe amayenda m'magazi am'magazi.

Kuwunika magawo a cholinesterase ndikofunikira kotero kuti kusintha kulikonse kungazindikiridwe ndikuchiritsidwa mwachangu, kupewa zovuta kwa munthuyo.

Ndi chiyani

Kuyeza kwa cholinesterase kumalimbikitsidwa ndi dokotala makamaka kuti aziona kuchuluka kwa alimi, mwachitsanzo, mankhwala ophera tizilombo komanso mankhwala ophera tizilombo.

Kuphatikiza apo, kuchuluka kwa mavitaminiwa kungapemphedwe kuwunika odwala omwe ali ndi matenda a chiwindi, makamaka omwe adalitsika chiwindi, chifukwa nthawi zambiri amachepetsa ma cholinesterase.

Mlingo wa cholinesterase amathanso kuwonetsedwa kwa anthu omwe asintha zomwe zimasokoneza magwiridwe antchito kapena kupanga kwa enzyme iyi.

Malingaliro owonetsera

Zoyeserera za Cholinesterase zimayenderana malinga ndi labotale ndi zida zomwe zimagwiritsidwa ntchito poyesa. Chifukwa chake, malingaliro oyenera akhoza kukhala pakati pa:

• Amuna: 4620 - 11500 U / L.
• Akazi: 3930 - 10800 U / L.

Kuyezetsa kumeneku kumachitika monga kuyesa magazi ena aliwonse, ndiye kuti, magazi ochepa amatengedwa ndikutumizidwa ku labotale kuti ikayesedwe ndi gawo la biochemistry. Malinga ndi labotale itha kulimbikitsidwa kusala kudya kwa maola osachepera 4.

Zomwe zotsatira zake zikutanthauza

Inu misinkhu otsika ya cholinesterase makamaka imawonetsa kupezeka kwakanthawi kwa mankhwala opha tizilombo a organophosphate, omwe ndi zinthu zomwe zimapezeka mu mankhwala ophera tizilombo, mankhwala ophera tizilombo ndi ma herbicides omwe amatha kuletsa ntchito ya enzyme iyi, zomwe zimapangitsa kuti acetylcholine ichulukane ndipo zomwe zitha kubweretsa kuwonekera kwa zizindikilo, monga :

• Kukokana;
• Kutsekula m'mimba;
• Kusanza;
• Kuchuluka kwa mate;
• Zowoneka zovuta;
• Kuchepetsa kuthamanga kwa magazi;
• Minofu kufooka;
• Kufa ziwalo.

Ngakhale kuchepa kwa milingo ya cholinesterase kumakhudzana kwambiri ndi kuledzeretsa, pakhoza kukhalanso ndi kuchepa kwa mavitaminiwa ngati matenda a chiwindi, chiwindi, kupsinjika kwa mtima, matenda opatsirana komanso infarction.

Chifukwa chake, ndikofunikira kuti zotsatira za mayeso a cholinesterase zimasuliridwe limodzi ndi zotsatira za mayeso ena kuti chomwe chimapangitsa kuchepa kwa enzyme ichi chizindikiridwe ndipo chithandizo choyenera kwambiri chitha kuwonetsedwa.

Mbali inayi, milingo yayikulu wa cholinesterase, nthawi zambiri zimachitika chifukwa cha kunenepa kwambiri, matenda ashuga, nephrotic syndrome ndi hyperthyroidism.