Vincristine: ndi chiyani, ndi chiyani komanso zotsatirapo zake

Zamkati

• Ndi chiyani
• Momwe mungagwiritsire ntchito
• Zotsutsana
• Zotsatira zoyipa

Vincristine ndiye mankhwala opangidwa ndi antineoplastic omwe amadziwika kuti Oncovin, akuwonetsedwa kuti azitha kuchiza mitundu ingapo ya khansa, kuphatikizapo khansa ya m'magazi, mapapo ndi khansa ya m'mawere.

Zomwe amachita ndikuti asokoneze kagayidwe kake ka amino acid ndikuletsa magawano am'magawo, zomwe zimapangitsa kuti khansa ifalikire mthupi lonse.

Mankhwalawa amapezeka ngati jakisoni ndipo amayenera kuperekedwa ndi akatswiri azaumoyo.

Ndi chiyani

Vincristine ndi mankhwala omwe amawonetsedwa pochiza mitundu yotsatira ya khansa:

• Pachimake lymphoid khansa ya m'magazi;
• Neuroblastoma;
• Chotupa cha Wilms;
• Khansa ya m'mawere;
• Khansa ya m'mapapo;
• Khansa yamchiberekero;
• Khansa ya pachibelekero;
• Khansa yoyipa;
• Hodgkin's and non-Hodgkin's lymphoma;
• Sarcoma ya Ewing;
• Osteosarcoma;
• Khansa ya khansa yoyipa.

Kuphatikiza apo, chida ichi chikuwonetsedwanso zochizira mycosis fungoides ndi idiopathic thrombocytopenic purpura. Phunzirani zomwe zili komanso momwe mungadziwire zizindikiro za idiopathic thrombocytopenic purpura.

Momwe mungagwiritsire ntchito

Mankhwalawa ayenera kuperekedwa kudzera m'mitsempha, ndi katswiri wazachipatala, ndipo mlingo ndi nthawi yothandizirayo ziyenera kutsimikiziridwa ndi oncologist.

Mwambiri, mlingowu ndi motere:

Akuluakulu

• 0.01 mpaka 0.03 mg wa Vincristine pa kg ya kulemera kwa thupi, ngati mlingo umodzi, masiku asanu ndi awiri aliwonse.

Ana

• Pamwamba pa 10 kg: Yendetsani 1.5 mpaka 2 mg wa Vincristine pa mita mita imodzi, ngati mlingo umodzi, masiku asanu ndi awiri;
• Ndi makilogalamu 10 kapena ochepera: Tsatirani 0.05 mg wa Vincristine pa kilogalamu yolemera thupi, ngati mlingo umodzi, masiku asanu ndi awiri aliwonse.

Kutalika kwa chithandizo kuyenera kutsimikiziridwa ndi oncologist.

Zotsutsana

Mankhwalawa amatsutsana ndi anthu omwe ali ndi hypersensitivity ku zigawo za fomuyi ndi odwala omwe ali ndi matenda a Charcot-Marie-Tooth.

Kuphatikiza apo, sayeneranso kugwiritsidwa ntchito ndi amayi apakati ndi amayi omwe akuyamwitsa ayenera kusiya kuyamwa mkaka akamamwa mankhwala ndi vincristine.

Zotsatira zoyipa

Zina mwazovuta zomwe zimachitika mukamamwa mankhwala a vincristine ndikutaya tsitsi, kudzimbidwa, kupweteka mthupi, kuchepa kwama cell oyera, kusowa chidwi, kuyenda movutikira komanso kutaya kwa malingaliro.

Zotsatira zoyipa kwambiri zomwe zitha kuchitika ndimatenda a neuromuscular.