Kulephera kwa testicular

Kulephera kwa testicular kumachitika pamene machende sangathe kutulutsa umuna kapena mahomoni achimuna, monga testosterone.

Kulephera kwa testicular sikachilendo. Zoyambitsa zimaphatikizapo:

• Mankhwala ena, kuphatikizapo glucocorticoids, ketoconazole, chemotherapy, ndi mankhwala opioid opweteka
• Matenda omwe amakhudza machende, kuphatikizapo hemochromatosis, mumps, orchitis, khansa ya testicular, testicular torsion, ndi varicocele
• Kuvulala kapena kupwetekedwa kwa machende
• Kunenepa kwambiri
• Matenda achibadwa, monga Klinefelter syndrome kapena Prader-Willi matenda
• Matenda ena, monga cystic fibrosis

Zotsatirazi zitha kuwonjezera chiopsezo cha testicular kulephera:

• Zochita zomwe zimapweteka pafupipafupi, monga kukwera njinga yamoto kapena njinga
• Kugwiritsa ntchito chamba pafupipafupi komanso molimba
• Machende osatsitsidwa pakubadwa

Zizindikiro zimadalira msinkhu womwe testicular imayamba, musanathe kapena mutatha msinkhu.

Zizindikiro zimaphatikizapo:

• Kuchepetsa kutalika
• Mawere okulitsidwa (gynecomastia)
• Kusabereka
• Kutayika kwa minofu
• Kupanda kugonana (libido)
• Kutaya tsitsi laakhwapa ndi malo obisika
• Kukula pang'ono kapena kuchepa kwa mikhalidwe yachiwerewere yachiwerewere (kukula kwa tsitsi, kukulitsa kwa ziboda, kukulitsa kwa mbolo, kusintha kwa mawu)

Amuna amathanso kuzindikira kuti safunika kumeta pafupipafupi.

Kuyezetsa thupi kumatha kuwonetsa:

• Ziwalo zoberekera zomwe sizimawoneka bwino ngati amuna kapena akazi (nthawi zambiri zimapezeka ali akhanda)
• Machende ang'onoang'ono, olimba
• Chotupa kapena misa yachilendo machende kapena pamatumbo

Mayeso ena atha kuwonetsa kuchepa kwa mchere wam'mafupa. Kuyezetsa magazi kumatha kuwonetsa kuchepa kwa testosterone komanso kuchuluka kwa ma prolactin, FSH, ndi LH (amadziwika ngati vutoli ndiloyambira kapena lachiwiri).

Ngati nkhawa yanu ndi yobereka, wothandizira zaumoyo wanu amathanso kuyitanitsa umuna kuti awone kuchuluka kwa umuna wabwino womwe mukupanga.

Nthawi zina, ma ultrasound a mayesowa amalamulidwa.

Kulephera kwa testicular ndi testosterone komwe kumakhala kovuta kumatha kukhala kovuta kuwazindikira mwa amuna akulu chifukwa mulingo wa testosterone nthawi zambiri umachepa pang'onopang'ono ndi ukalamba.

Ma hormone owonjezera amatha kuthandizira mitundu ina ya testicular kulephera. Mankhwalawa amatchedwa testosterone replacement therapy (TRT). TRT itha kuperekedwa ngati gel osakaniza, chigamba, jakisoni, kapena kuyika.

Kupewa mankhwala kapena ntchito yomwe ikuyambitsa vutoli kumatha kubweretsanso thukuta kukhala labwinobwino.

Mitundu yambiri yakulephera kwa testicular siyingasinthidwe. TRT itha kuthandizira kusintha zizindikilo, ngakhale sizingabwezeretse chonde.

Amuna omwe ali ndi chemotherapy yomwe ingayambitse testicular kulephera ayenera kukambirana za kuzizira kwa umuna asanayambe kulandira mankhwala.

Kulephera kwa testicular komwe kumayamba msinkhu wothamanga kumalepheretsa kukula kwa thupi. Zimatha kuletsa mawonekedwe achimuna achikulire (monga mawu akuya ndi ndevu) kuti asakule. Izi zitha kuchiritsidwa ndi TRT.

Amuna omwe ali pa TRT ayenera kuyang'aniridwa mosamala ndi dokotala. TRT itha kuyambitsa izi:

• Kukula kwa prostate, komwe kumabweretsa mavuto pokodza
• Kuundana kwamagazi
• Kusintha kwa tulo ndi malingaliro

Funsani msonkhano ndi omwe amakupatsani ngati muli ndi zizindikiro za testicular kulephera.

Komanso itanani omwe akukuthandizani ngati muli pa TRT ndipo mukuganiza kuti mukukumana ndi zovuta zamankhwala.

Pewani zochitika zowopsa ngati zingatheke.

Primary hypogonadism - wamwamuna

• Matenda a testicular
• Kutengera kwamwamuna kubereka

Allan CA, McLachlan RI. Matenda a Androgen akusowa. Mu: Jameson JL, De Groot LJ, de Kretser DM, et al, olemba. Endocrinology: Akuluakulu ndi Ana. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier Saunders; 2016: chap 139.

Morgentaler A, Zitzmann M, Traish AM, ndi al. Malingaliro oyambira okhudzana ndi kusowa kwa testosterone ndi chithandizo: malingaliro apadziko lonse lapansi ogwirizana. Chipatala cha Mayo. 2016; 91 (7): 881-896. PMID: 27313122 www.ncbi.nlm.nih.gov/pubmed/27313122. (Adasankhidwa)

Tsamba la US Food and Drug Administration. Kuyankhulana kwachitetezo cha mankhwala a FDA: FDA imachenjeza za kugwiritsa ntchito mankhwala a testosterone a testosterone chifukwa cha ukalamba; Pamafunika kusintha kwa zilembo kuti zidziwitse za chiwopsezo chowonjezeka cha matenda amtima ndi sitiroko ndikugwiritsa ntchito. www.fda.gov/Drugs/DrugSafety/ucm436259.htm. Idasinthidwa pa February 26, 2018. Idapezeka pa Meyi 20, 2019.