Magawo azigawo glomerulosclerosis

Magawo azigawo za glomerulosclerosis ndi minofu yofiyira mu fyuluta ya impso. Kapangidwe kameneka kamatchedwa glomerulus. Glomeruli imagwira ngati zosefera zomwe zimathandiza thupi kuchotsa zinthu zoyipa. Impso iliyonse imakhala ndi glomeruli masauzande ambiri.

"Zowonekera" zikutanthauza kuti ena mwa ma glomeruli amakhala ndi zipsera. Zina zimakhala zachilendo. "Segmental" amatanthauza kuti gawo limodzi lokha la glomerulus ndi lomwe limawonongeka.

Zomwe zimayambitsa matenda otchedwa glomerulosclerosis nthawi zambiri sizidziwika.

Vutoli limakhudza ana ndi akulu omwe. Zimachitika kawirikawiri mwa amuna ndi anyamata. Zimakhalanso zofala ku Africa America. Magawo azigawo za glomerulosclerosis amayambitsa kotala la matenda onse a nephrotic.

Zoyambitsa zodziwika ndizo:

• Mankhwala monga heroin, bisphosphonates, anabolic steroids
• Matenda
• Mavuto obadwa nawo obadwa nawo
• Kunenepa kwambiri
• Reflux nephropathy (mkhalidwe womwe mkodzo umathamangira chammbuyo kuchokera ku chikhodzodzo kupita ku impso)
• Matenda a khungu
• Mankhwala ena

Zizindikiro zimaphatikizapo:

• Mkodzo wa thovu (kuchokera ku mapuloteni owonjezera mumkodzo)
• Kulakalaka kudya
• Kutupa, komwe kumatchedwa edema yodziwika bwino, kuchokera kumadzi amadzimadzi omwe amakhala mthupi
• Kulemera

Wothandizira zaumoyo adzayesa. Mayesowa atha kuwonetsa kutupa kwa minofu (edema) komanso kuthamanga kwa magazi. Zizindikiro za impso (aimpso) kulephera komanso madzimadzi ochulukirapo amatha kukula pamene matenda akuipiraipira.

Mayeso atha kuphatikiza:

• Kusokoneza impso
• Kuyesa kwa impso (magazi ndi mkodzo)
• Kupenda kwamadzi
• Mkodzo microscopy
• Mkodzo mapuloteni

Chithandizo chitha kukhala:

• Mankhwala ochepetsa kutentha kwa thupi.
• Mankhwala ochepetsa kuthamanga kwa magazi. Ena mwa mankhwalawa amathandizanso kuchepetsa kuchuluka kwa mapuloteni omwe amatayikira mkodzo.
• Mankhwala ochotsera madzimadzi owonjezera (diuretic kapena "mapiritsi amadzi").
• Zakudya zochepa za sodium kuti muchepetse kutupa komanso kuthamanga kwa magazi.

Cholinga cha chithandizo ndikuwongolera zizindikilo za nephrotic syndrome ndikupewa kulephera kwa impso. Mankhwalawa atha kuphatikiza:

• Maantibayotiki oletsa kuteteza matenda
• Kuletsa zamadzimadzi
• Zakudya zonenepa kwambiri
• Zakudya zochepa kapena zochepa
• Vitamini D zowonjezera
• Dialysis
• Kuika impso

Gawo lalikulu la anthu omwe ali ndi glomerulosclerosis omwe amakhala ndi gawo limodzi kapena gawo limodzi amakhala ndi vuto la impso.

Zovuta zingaphatikizepo:

• Kulephera kwa impso
• Matenda omaliza a impso
• Matenda
• Kusowa zakudya m'thupi
• Matenda a Nephrotic

Itanani omwe akukuthandizani mukakhala ndi zodwala, makamaka ngati pali:

• Malungo
• Ululu pokodza
• Kuchepetsa mkodzo

Palibe kupewa komwe kumadziwika.

Chigawo glomerulosclerosis; Focal sclerosis ndi hyalinosis

• Njira yamikodzo yamwamuna

Appel GB, D'Agati VD. Pulayimale ndi yachiwiri (yopanda majini) zomwe zimayambitsa glomerulosclerosis. Mu: Feehally J, Floege J, Tonelli M, Johnson RJ, olemba. Chachikulu Chachipatala Nephrology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2019: mutu 18.

Appel GB, Radhakrishnan J. Glomerular zovuta ndi nephrotic syndromes. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil.Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 121.

Pendergraft WF, Nachman PH, Jennette JC, Falk RJ. Matenda oyamba a glomerular. Mu: Skorecki K, Taal MW, Chertow GM, Marsden PA, Yu ASL, olemba. Brenner ndi Rector a Impso. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 32.