Kuyesa magazi kwa TBG

Kuyezetsa magazi kwa TBG kumayeza kuchuluka kwa puloteni yomwe imasuntha mahomoni a chithokomiro mthupi lanu lonse. Puloteni iyi imatchedwa thyroxine binding globulin (TBG).

Amayesedwa magazi kenako amatumizidwa ku labotale kukayesedwa.

Mankhwala ena ndi mankhwala angakhudze zotsatira za mayeso. Wothandizira zaumoyo wanu akhoza kukuwuzani kuti musiye kumwa mankhwala kwakanthawi kochepa musanayezedwe. Osasiya kumwa mankhwala osalankhula ndi omwe akukuthandizani.

Mankhwalawa ndi mankhwalawa atha kukulitsa kuchuluka kwa TBG:

• Estrogens, yomwe imapezeka m'mapiritsi oletsa kubereka ndi mankhwala obwezeretsa estrogen
• Heroin
• Methadone
• Phenothiazines (mankhwala ena a antipsychotic)

Mankhwala otsatirawa atha kutsitsa kuchuluka kwa TBG:

• Depakote kapena depakene (wotchedwanso valproic acid)
• Dilantin (wotchedwanso phenytoin)
• Mlingo waukulu wa salicylates, kuphatikizapo aspirin
• Mahomoni achimuna, kuphatikiza androgens ndi testosterone
• Prednisone

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kubaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka kapena kuvulala pang'ono. Izi posachedwa zichoka.

Mayesowa angachitike kuti mupeze zovuta za chithokomiro chanu.

Mitundu yabwinobwino ndi ma micrograms 13 mpaka 39 pa deciliter (mcg / dL), kapena nanomoles 150 mpaka 360 pa lita (nmol / L).

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amatha kuyesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Kuchuluka kwa TBG kumatha kukhala chifukwa cha:

• Pachimake pakatikati porphyria (matenda osowa kagayidwe kachakudya)
• Hypothyroidism (chithokomiro chosagwira ntchito)
• Matenda a chiwindi
• Mimba (kuchuluka kwa TBG kumawonjezeka nthawi yapakati)

Chidziwitso: Matenda a TBG nthawi zambiri amakhala obadwa mwa ana obadwa kumene.

Kuchepetsa milingo ya TBG kumatha kukhala chifukwa cha:

• Matenda oopsa
• Acromegaly (matenda omwe amayamba chifukwa cha kukula kwambiri kwa mahomoni)
• Hyperthyroidism (chithokomiro chopitilira muyeso)
• Kusowa zakudya m'thupi
• Nephrotic syndrome (zizindikiro zomwe zimawonetsa kuwonongeka kwa impso zilipo)
• Kusokonezeka maganizo chifukwa cha opaleshoni

Mulingo wapakati kapena wotsika wa TBG umakhudza ubale wapakati pa T4 yathunthu ndi kuyezetsa magazi kwaulere T4. Kusintha kwa milingo ya TBG kumatha kusintha mulingo woyenera wa levothyroxine m'malo mwa anthu omwe ali ndi hypothyroidism.

Pali chiopsezo chochepa chotenga magazi anu. Mitsempha ndi mitsempha imasiyana mosiyanasiyana kuchokera pa munthu wina kupita kwina komanso kuchokera mbali imodzi ya thupi kupita mbali inayo. Kupeza magazi kuchokera kwa anthu ena kumatha kukhala kovuta kuposa ena.

Zowopsa zina zokoka magazi ndizochepa, koma mwina ndi izi:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Ma punctures angapo kuti mupeze mitsempha
• Hematoma (magazi omanga pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Seramu thyroxine womangiriza globulin; Mulingo wa TBG; Mulingo wa Seramu TBG; Hypothyroidism - TBG; Hyperthyroidism - TBG; Chithokomiro chosagwira - TBG; Chithokomiro chopitilira muyeso - TBG

• Kuyezetsa magazi

Guber HA, Farag AF. Kuwunika kwa endocrine ntchito. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 24.

Kruse JA. Matenda a chithokomiro. Mu: Parrillo JE, Dellinger RP, olemba. Zovuta Zosamalira Mankhwala: Mfundo Zazidziwitso ndi Kuwongolera Kwa Akuluakulu. 5th ed. Philadelphia, PA: Elsevier; 2019: mutu 57.

Salvatore D, Cohen R, Kopp PA, Larsen PR. Chithokomiro cha pathophysiology ndikuwunika matenda. Mu: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, olemba. Buku la Williams la Endocrinology. Wolemba 14th. Philadelphia, PA: Elsevier; 2020: mutu 11.