Mlembi: Virginia Floyd
Tsiku La Chilengedwe: 12 Ogasiti 2021
Sinthani Tsiku: 14 Novembala 2024
Anonim
Congenital adrenal hyperplasia : Etiology ,Pathophysiology ,Clinical features ,Diagnosis ,Treatment
Kanema: Congenital adrenal hyperplasia : Etiology ,Pathophysiology ,Clinical features ,Diagnosis ,Treatment

17-OH progesterone ndiyeso loyesa magazi lomwe limayeza kuchuluka kwa 17-OH progesterone. Iyi ndi hormone yopangidwa ndi adrenal gland ndi gland gland.

Muyenera kuyesa magazi. Nthawi zambiri, magazi amatengedwa pamitsempha yomwe ili mkati mwa chigongono kapena kumbuyo kwa dzanja.

Kwa makanda kapena ana aang'ono, chida chakuthwa chotchedwa lancet chitha kugwiritsidwa ntchito kuboola khungu.

  • Mwazi umasonkhanitsa mu chubu chaching'ono chagalasi chotchedwa pipette, kapena pa slide kapena mzere woyesera.
  • Bandeji amaikidwa pamalopo kuti athetse magazi.

Mankhwala ambiri amatha kusokoneza zotsatira zoyesa magazi.

  • Wothandizira zaumoyo wanu angakuuzeni ngati mukufuna kusiya kumwa mankhwala musanayezeke.
  • Osayimitsa kapena kusintha mankhwala anu osalankhula ndi omwe akukuthandizani kaye.

Mutha kumva kupweteka pang'ono kapena mbola pamene singano imayikidwa. Muthanso kumva kupwetekedwa pamalowo magazi atatengedwa.

Kugwiritsa ntchito kwakukulu kwa mayesowa ndikuwunika makanda kuti ali ndi vuto lobadwa nalo lomwe limakhudza adrenal gland, yotchedwa congenital adrenal hyperplasia (CAH). Nthawi zambiri zimachitidwa kwa makanda omwe amabadwa ndi maliseche akunja omwe samawoneka bwino ngati a mnyamata kapena mtsikana.


Kuyesaku kumagwiritsidwanso ntchito kuzindikira anthu omwe amakhala ndi zizindikilo za CAH pambuyo pake m'moyo, chikhalidwe chotchedwa nonclassical adrenal hyperplasia.

Wothandizira angalimbikitse mayesowa kwa azimayi kapena atsikana omwe ali ndi zikhalidwe zamwamuna monga:

  • Kukula kwakukulu kwa tsitsi m'malo omwe amuna achikulire amakula tsitsi
  • Mawu akuya kapena kuwonjezeka kwa minofu
  • Kupanda nthawi
  • Kusabereka

Makhalidwe abwinobwino komanso osazolowereka amasiyana kwa makanda obadwa ochepa. Mwambiri, zotsatira zabwinobwino ndi izi:

  • Makanda opitilira maola 24 - ochepera ma 400 mpaka 600 nanograms pa deciliter (ng / dL) kapena 12.12 mpaka 18.18 nanomoles pa lita (nmol / L)
  • Ana asanakwane msinkhu kuzungulira 100 ng / dL kapena 3.03 nmol / L
  • Akuluakulu - ochepera 200 ng / dL kapena 6.06 nmol / L.

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Zitsanzo pamwambapa zikuwonetsa muyeso wamba wazotsatira zamayesowa. Ma labotale ena amagwiritsa ntchito miyeso yosiyana kapena amatha kuyesa mitundu yosiyanasiyana.


Mulingo wapamwamba wa 17-OH progesterone ukhoza kukhala chifukwa cha:

  • Zotupa za adrenal gland
  • Kobadwa nako adrenal hyperplasia (CAH)

Kwa makanda omwe ali ndi CAH, mulingo wa 17-OHP amakhala pakati pa 2,000 mpaka 40,000 ng / dL kapena 60.6 mpaka 1212 nmol / L. Mwa akuluakulu, mulingo woposa 200 ng / dL kapena 6.06 nmol / L atha kukhala chifukwa cha nonclassical adrenal hyperplasia.

Wothandizira anu atha kuyesa kuyesa kwa ACTH ngati mulingo wa progesterone 17-OH uli pakati pa 200 mpaka 800 ng / dL kapena 6.06 mpaka 24.24 nmol / L.

17-hydroxyprogesterone; Progesterone - 17-OH

Guber HA, Farag AF. Kuwunika kwa endocrine ntchito. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 24.

Rey RA, Josso N. Kuzindikira ndikuchiza zovuta zakukula kwakugonana. Mu: Jameson JL, De Groot LJ, de Kretser DM, et al, olemba. Endocrinology: Akuluakulu ndi Ana. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier Saunders; 2016: chap 119.

PC yoyera. Congenital adrenal hyperplasia ndi zovuta zina. Mu: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 594.


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