Wophatikizira

Zamkati

• Alendronate mwina singagwire bwino ntchito ndipo itha kuwononga kholingo (chubu pakati pakamwa ndi m'mimba) kapena kuyambitsa zilonda mkamwa ngati singatengedwe molingana ndi malangizo awa. Uzani dokotala wanu ngati simukumvetsa, mukuganiza kuti simukumbukira, kapena simungathe kutsatira malangizo awa:
• Musanatenge alendronate,
• Alendronate imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikiro izi kapena zomwe zalembedwa mgawo la ZOCHITIKA, itanani dokotala wanu musanatengeko alendronate:
• Zizindikiro za bongo zingaphatikizepo izi:

Alendronate amagwiritsidwa ntchito pochiza komanso kupewa kufooka kwa mafupa (vuto lomwe mafupa amafooka ndi kufooka ndikuphwanya mosavuta) mwa amayi omwe adayamba kusamba ('' kusintha kwa moyo, '' kutha kwa msambo) komanso kuchiza kufooka kwa mafupa kwa amuna. Alendronate imagwiritsidwanso ntchito kuchiza kufooka kwa mafupa kwa abambo ndi amai omwe akutenga corticosteroids (mtundu wa mankhwala omwe angayambitse kufooka kwa mafupa kwa odwala ena). Alendronate imagwiritsidwanso ntchito pochiza matenda a Paget a mafupa (mkhalidwe womwe mafupa amakhala ofewa komanso ofooka ndipo amatha kupunduka, kupweteka, kapena kusweka mosavuta). Alendronate ali mgulu la mankhwala otchedwa bisphosphonates. Zimagwira ntchito popewa kuwonongeka kwa mafupa ndikuwonjezera kuchuluka kwa mafupa (makulidwe).

Alendronate amabwera ngati piritsi, piritsi losalala, komanso yankho (madzi) kuti atenge pakamwa. Njira yothetsera vutoli nthawi zambiri imatengedwa m'mimba yopanda kanthu kamodzi pa sabata m'mawa. Mapiritsi a 5-mg ndi 10-mg nthawi zambiri amatengedwa m'mimba yopanda kanthu kamodzi patsiku m'mawa, ndipo mapiritsi a 35-mg ndi 70-mg amatengedwa m'mimba yopanda kanthu kamodzi pa sabata m'mawa. Mapiritsi a 40-mg amatengedwa kamodzi patsiku m'mawa kwa miyezi isanu ndi umodzi kuti athe kuchiza matenda a Paget a mafupa. Mapiritsi otsekemera nthawi zambiri amatengedwa m'mimba yopanda kanthu kamodzi pamlungu m'mawa. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani alendronate ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Alendronate mwina singagwire bwino ntchito ndipo itha kuwononga kholingo (chubu pakati pakamwa ndi m'mimba) kapena kuyambitsa zilonda mkamwa ngati singatengedwe molingana ndi malangizo awa. Uzani dokotala wanu ngati simukumvetsa, mukuganiza kuti simukumbukira, kapena simungathe kutsatira malangizo awa:

• Muyenera kutenga alendronate mukangodzuka m'mawa, musanadye kapena kumwa chilichonse. Osatengera alendronate nthawi yogona kapena musanadzuke ndi kutuluka pabedi tsikulo.
• Mukamamwa alendronate, musadye, kumwa, kapena kumwa mankhwala aliwonse (kuphatikiza mavitamini kapena maantacid) osachepera mphindi 30. Osagona kwa mphindi 30 mutatenga alendronate. Khalani chilili kapena kuimirira mpaka mphindi 30 zitadutsa ndipo mwadya chakudya chanu choyamba tsikulo.
• Ngati mukumwa mapiritsi a alendronate, imwani mapiritsiwo ndi kapu yathunthu (180 mpaka 240 mL) yamadzi wamba. Musamamwe mapiritsi a alendronate ndi tiyi, khofi, msuzi, mkaka, madzi amchere, madzi owala, kapena madzi aliwonse kupatula madzi wamba. Kumeza mapiritsi lonse; osagawanika, kutafuna kapena kuwaphwanya. Osayamwa mapiritsi.
• Ngati mukumwa mankhwala otchedwa alendronate oral solution, imwani madzi osachepera 2 milliliters [1/4 chikho] ya madzi mutamwa mankhwala amchere a alendronate. Musamamwe mankhwala a alendronate ndi tiyi, khofi, msuzi, mkaka, madzi amchere, madzi owala, kapena madzi aliwonse kupatula madzi wamba.
• Ngati mukumwa mapiritsi a alendronate effervescent, sungunulani piritsi limodzi lokhala ndi mafuta okwanira mugalasi yathunthu (mamililita 120) amadzi akumwa opanda kaboni osamwa. Osasungunula mapiritsi a alendronate ophera ndi tiyi, khofi, madzi, mkaka, madzi amchere, madzi owala, kapena madzi aliwonse kupatula madzi wamba. Dikirani osachepera mphindi 5 kuchokera pomwe chimbudzi chimaima, yesani yankho kwa masekondi 10 ndikumwa. Osameza, kuyamwa, kapena kutafuna mapiritsi osungunuka.

Alendronate amalamulira kufooka kwa mafupa ndi matenda a Paget a mafupa koma samachiritsa izi. Zitha kutenga miyezi itatu kapena kupitilira apo kuti mafupa anu asanakule. Alendronate amathandizira kuchiza ndikupewa kufooka kwa mafupa pokhapokha atamwa nthawi zonse. Pitilizani kutenga alendronate ngakhale mukumva bwino. Osasiya kumwa alendronate osalankhula ndi adotolo, koma lankhulani ndi dokotala nthawi ndi nthawi za ngati mukufunikirabe kumwa alendronate.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge alendronate,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la alendronate kapena mankhwala aliwonse.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: angiogenesis inhibitors monga bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), kapena sunitinib (Sutent); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Ibu-Tab, Motrin, ena) ndi naproxen (Aleve, Naprelan, Naprosyn, ena); khansa chemotherapy; kapena steroids yamlomo monga dexamethasone, methylprednisolone (Medrol), ndi prednisone (Rayos). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa mankhwala ena aliwonse kuphatikiza zowonjezera mavitamini, mavitamini, kapena maantacids pakamwa, tengani osachepera mphindi 30 mutatenga alendronate.
• uzani dokotala wanu ngati mukulephera kukhala wowongoka kapena kuyimirira molunjika kwa mphindi zosachepera 30, ngati mwakhalapo ndi calcium yotsika pang'ono m'magazi anu, chiopsezo chopuma chakudya kapena madzi m'mapapu, kapena ngati khalani ndi vuto lililonse ndi kummero kwanu. Dokotala wanu akhoza kukuwuzani kuti musamamwe alendronate.
• uzani dokotala ngati mukumwa mankhwala a radiation kapena ngati mukudya zakudya zoperewera ndi sodium (ngati mutenga mapiritsi a effervescent); ndipo ngati mwakhalapo kapena munakhalapo ndi kuchepa kwa magazi (momwe maselo ofiira samabweretsa mpweya wokwanira kumadera onse amthupi); mlingo wochepa wa vitamini D mthupi lanu; zovuta kumeza; kutentha pa chifuwa; zilonda zam'mimba kapena mavuto ena am'mimba; khansa; matenda amtundu uliwonse, makamaka mkamwa mwanu; mavuto pakamwa panu, mano, kapena m'kamwa zilizonse zomwe zimaletsa magazi anu kuti asamaumbike bwino; kapena matenda a mano kapena impso.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukuyamwitsa. Komanso muuzeni dokotala ngati mukufuna kukhala ndi pakati nthawi ina iliyonse m'tsogolo, chifukwa alendronate amatha kukhala mthupi lanu kwazaka zambiri mutasiya kumwa. Itanani dokotala wanu mukakhala ndi pakati mukamamwa kapena mukalandira chithandizo.
• muyenera kudziwa kuti alendronate imatha kuyambitsa matenda a osteonecrosis a nsagwada (ONJ, vuto lalikulu la nsagwada), makamaka ngati mwachitidwa opareshoni yamazinyo kapena chithandizo mukamamwa mankhwalawa. Dokotala wamano ayenera kuwerengera mano anu ndikuchita chithandizo chilichonse chofunikira, kuphatikiza kuyeretsa kapena kukonza mano oyenera, musanayambe kumwa alendronate. Onetsetsani kutsuka mano ndikutsuka mkamwa mwanu moyenera mukamamwa alendronate. Lankhulani ndi dokotala musanalandire chithandizo chilichonse cha mano mukamamwa mankhwalawa.
• muyenera kudziwa kuti alendronate imatha kupweteketsa mafupa, minofu, kapena mafupa. Mutha kuyamba kumva kuwawa pasanathe masiku, miyezi, kapena zaka mutangotenga alendronate. Ngakhale kupweteka kwamtunduwu kumatha kuyamba mutatenga alendronate kwakanthawi, ndikofunikira kuti inu ndi dokotala muzindikire kuti mwina imayambitsidwa ndi alendronate. Itanani dokotala wanu nthawi yomweyo ngati mukumva kuwawa kwambiri nthawi iliyonse mukamamwa mankhwala ndi alendronate. Dokotala wanu angakuuzeni kuti musiye kumwa alendronate ndipo ululu wanu ukhoza kutha mukasiya kumwa mankhwalawo.
• lankhulani ndi dokotala wanu pazinthu zina zomwe mungachite kuti muteteze kufooka kwa mafupa kuti kukula kapena kukulira. Dokotala wanu angakuuzeni kuti mupewe kusuta fodya komanso kumwa mowa wambiri komanso kutsatira njira zolimbitsa thupi zolimbitsa thupi.

Muyenera kudya ndi kumwa zakudya ndi zakumwa zambiri zomwe zili ndi calcium ndi vitamini D wochuluka mukamamwa alendronate. Dokotala wanu angakuuzeni zakudya ndi zakumwa zabwino zomwe zimapatsa thanzi komanso kuchuluka kwa zosowa zanu tsiku lililonse. Ngati zikukuvutani kudya zakudya zokwanira, uzani dokotala wanu. Zikatero, dokotala wanu angakupatseni mankhwala kapena akuwonjezerani chowonjezera.

Ngati mwaphonya mlingo wa alendronate kamodzi-tsiku, musadzamwe tsiku lomwelo. Pitani muyezo womwe mwaphonya ndikumwa kamodzi m'mawa mwake monga mwanthawi zonse. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Ngati mwaphonya mlingo wa alendronate kamodzi kamodzi pamlungu, imwani mlingowu m'mawa mukakumbukira. Kenako mubwerere kumwa kamodzi kamodzi sabata iliyonse patsiku lanu lokhazikika. Musatenge mlingo wowirikiza kuti mugwiritse ntchito yomwe mwaphonya, ndipo musamwe mowa woposa umodzi tsiku limodzi.

Alendronate imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kupweteka m'mimba
• kudzimbidwa
• kutsegula m'mimba
• mpweya
• Kutupa kapena kukhuta m'mimba
• kusintha kwa kulawa chakudya
• mutu
• chizungulire
• kutupa kwa mafupa, manja, kapena miyendo
• kutuluka kwa minofu, kupindika, kapena kukokana

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikiro izi kapena zomwe zalembedwa mgawo la ZOCHITIKA, itanani dokotala wanu musanatengeko alendronate:

• kutentha pa chifuwa kwatsopano kapena kukulira
• zovuta kumeza
• kupweteka pakumeza
• kupweteka pachifuwa
• masanzi amagazi kapena masanzi omwe amawoneka ngati malo a khofi
• wakuda, wodikira, kapena chimbudzi chamagazi
• malungo
• matuza kapena khungu losenda
• kuthamanga (kumatha kukulitsidwa ndi kuwala kwa dzuwa)
• kuyabwa
• ming'oma
• kutupa kwa maso, nkhope, milomo, lilime, kapena pakhosi
• kuvuta kupuma
• ukali
• nkhama zopweteka kapena zotupa
• kumasula mano
• dzanzi kapena kumverera kolemetsa pachibwano
• kuchiritsa koyipa kwa nsagwada
• kupweteka kwa diso
• kupweteka, kupweteka m'chiuno, kubuula, kapena ntchafu

Kutenga mankhwala a bisphosphonate monga alendronate a kufooka kwa mafupa kungapangitse chiopsezo kuti muswe mafupa anu. Mutha kumva kupweteka m'chiuno mwanu, kubuula kwanu, kapena ntchafu zanu kwa milungu ingapo kapena miyezi isanaphwanye mafupa, ndipo mutha kupeza kuti limodzi kapena mafupa anu onse a ntchafu athyoledwa ngakhale simunagwe kapena kukumana ndi zoopsa zina. Si zachilendo kuti fupa la ntchafu lathyoka mwa anthu athanzi, koma anthu omwe ali ndi matenda otupa mafupa amatha kuphwanya fupa ngakhale atapanda kutenga alendronate. Lankhulani ndi dokotala wanu za kuopsa kotenga alendronate.

Alendronate imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Musayimitse yankho la alendronate.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Pakadwala mopitirira muyeso, mupatseni mkaka wathunthu mkaka ndikuyimbira malo oyang'anira poyizoni ku 1-800-222-1222. Ngati wovulalayo wagwa kapena sakupuma, itanani oyang'anira zadzidzidzi ku 911. Musalole kuti wovulalayo agone pansi ndipo musayese kumusambitsa.

Zizindikiro za bongo zingaphatikizepo izi:

• kutentha pa chifuwa
• nseru
• kupweteka m'mimba
• masanzi amagazi kapena masanzi omwe amawoneka ngati malo a khofi
• kuvuta kumeza kapena kupweteka mukamedza
• chimbudzi chamagazi kapena chakuda komanso chochedwa

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena a labu kuti muwone kuyankha kwa thupi lanu kwa alendronate.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Binosto^®
• Fosamax^®

• Fosamax^® Plus D (yokhala ndi Alendronate, Cholecalciferol)