Tolvaptan (magazi ochepa sodium)

Zamkati

• Musanatenge tolvaptan (Samsca),
• Tolvaptan (Samsca) itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo izi:

Tolvaptan (Samsca) itha kupangitsa kuti mulingo wa sodium m'magazi anu uwonjezeke kwambiri. Izi zitha kuyambitsa matenda osmotic demyelination syndrome (ODS; kuwonongeka kwamitsempha koopsa komwe kungayambitsidwe ndi kuwonjezeka kwamsanga kwa sodium). Uzani dokotala wanu ngati mumamwa kapena mumamwa mowa wambiri, ngati muli ndi vuto la kuperewera kwa zakudya m'thupi (thupi lilibe michere yofunikira kuti mukhale ndi thanzi labwino), komanso ngati mwakhalapo ndi matenda a chiwindi kapena kuchuluka kwa sodium m'magazi anu .

Inu ndi dokotala mutenga zinthu zina kuti muteteze ODS. Muyamba chithandizo chanu ndi tolvaptan (Samsca) kuchipatala kuti dokotala wanu akuyang'anitseni bwino. Ngati dokotala akukuuzani kuti mupitilize kumwa tolvaptan (Samsca) mutatuluka kuchipatala, simuyenera kuyambiranso kuyambiranso nokha. Muyenera kubwerera kuchipatala mukayambitsanso mankhwalawo.

Muyenera kumwa madzi mukamva ludzu lothandizira ODS mukamamwa mankhwala ndi tolvaptan (Samsca). Dokotala wanu sangakupatseni tolvaptan (Samsca) ngati mukulephera kumva kuti muli ndi ludzu. Muyenera kukhala ndi madzi akumwa nthawi zonse mukamalandira chithandizo.

Ngati mukumane ndi zizindikiro zotsatirazi za ODS, uzani dokotala nthawi yomweyo: kuvuta kuyankhula, kuvutika kumeza, kumva kuti chakudya kapena zakumwa zikugwira pakhosi panu, kuwodzera, kusokonezeka, kusintha kwa malingaliro, kusuntha kwa thupi komwe kuli kovuta kuwongolera, kufooka ya mikono kapena miyendo, kapena khunyu.

Muyenera kudziwa kuti tolvaptan imapezekanso ngati piritsi (Jynarque) kuti ichepetse kukula kwa impso mwa akulu omwe ali ndi matenda amtundu wina obadwa nawo. Ngati muli ndi matenda a impso, simuyenera kumwa tolvaptan (Samsca). Chifukwa cha kuopsa kwa vuto la chiwindi ndi tolvaptan, Jynarque imangopezeka pokhapokha pulogalamu yoletsedwa yogawa. Makinawa amangopereka chidziwitso cha mapiritsi a tolvaptan (Samsca) kuti athetse vuto la sodium m'magazi. Ngati mukugwiritsa ntchito mankhwalawa kuti muchepetse kukula kwa ntchito yanu ya impso, werengani monograph yotchedwa tolvaptan (matenda a impso).

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Chithandizo cha Mankhwala) mukayamba mankhwala ndi tolvaptan ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za chiopsezo chotenga tolvaptan (Samsca).

Tolvaptan (Samsca) amagwiritsidwa ntchito pochiza hyponatremia (otsika a sodium m'magazi) mwa anthu omwe ali ndi vuto la mtima (momwe mtima sungapope magazi okwanira kumadera onse amthupi), matenda amadzimadzi osayenera (SIADH; Mkhalidwe womwe thupi limatulutsa zinthu zachilengedwe zochulukirapo zomwe zimapangitsa thupi kusunga madzi) kapena mikhalidwe ina. Tolvaptan ali mgulu la mankhwala otchedwa vasopressin V₂ otsutsana nawo. Zimagwira ndikuwonjezera kuchuluka kwa madzi otuluka m'thupi ngati mkodzo. Kuchotsa madzimadzi mthupi kumathandizira kukulitsa kuchuluka kwa sodium m'magazi.

Tolvaptan (Samsca) amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku kapena wopanda chakudya kwa masiku osapitirira 30. Kumayambiriro kwa chithandizo chanu, mudzapatsidwa tolvaptan (Samsca) panthawi yokhazikika kuchipatala. Mukauzidwa kuti mutenge tolvaptan (Samsca) kunyumba mukamasulidwa, muyenera kumwa nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani tolvaptan (Samsca) ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu mwina angakuyambitseni pa tolvaptan (Samsca) wocheperako pang'ono pang'ono pang'onopang'ono ndikuwonjezerani mlingo wanu, osapitilira kamodzi pa maola 24 alionse.

Lankhulani ndi dokotala wanu zomwe muyenera kuchita mukasiya kumwa tolvaptan (Samsca). Muyenera kuchepetsa kuchuluka kwa madzimadzi omwe mumamwa, ndipo dokotala wanu adzakuyang'anirani mosamala panthawiyi.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge tolvaptan (Samsca),

• Uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi tolvaptan (Samsca, Jynarque), mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a tolvaptan. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• uzani dokotala ngati mukumwa mankhwala enaake ophera fungal monga ketoconazole (Nizoral) kapena itraconazole (Sporanox); clarithromycin (Biaxin); mankhwala ena a HIV monga indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), kapena saquinavir (Invirase); desmopressin (dDAVP, Yowonjezera); nefazodone; kapena telithromycin (Ketek). Dokotala wanu angakuuzeni kuti musamwe tolvaptan (Samsca) ngati mukumwa mankhwala amodzi kapena angapo.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: zoletsa ma angiotensin-converting enzyme (ACE) monga benazepril (Lotensin, ku Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (Prinivil, Zestril, in Zestoretic), moexipril , perindopril, (quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), ndi trandolapril (Tarka); angiotensin II receptor blockers monga candesartan (Atacand), eprosartan, irbesartan (Avapro, ku Avalidear), losartan , ku Hyzaar), olmesartan (Benicar, ku Benicar HCT, ku Tribenzor), telmisartan (Micardis, ku Twynsta), ndi valsartan (Diovan, Prexxartan, ku Entresto, ku Exforge); aprepitant (Emend); barbiturates monga phenobarbital; carbamazine (Carbatrol, Equetro, Tegretol); cyclosporine (Gengraf, Neoral, Sandimmune); desmopressin (dDAVP, Minirin, Noctiva), digoxin (Lanoxin); diltiazem (Cardizem, Diltzac, Tiazac); diuretics (mapiritsi amadzi); erythromycin (Erythromycin) ERYC, Erythrocin, PCE); fluconazole (Diflucan); phenytoin (Wofatsa mkati); zowonjezera potaziyamu; rifabutin (Mycobutin); rifampin (Rimactane, Rifadin, ku Rifater, ku Rifamate); rifapentine (Priftin); ndi verapamil (Calan, Verelan, ku Tarka). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi tolvaptan (Samsca), onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa kapena mukukonzekera kumwa, makamaka St John's wort.
• uzani dokotala wanu ngati muli ndi matenda a impso ndipo simukutulutsa mkodzo, ngati mukusanza kwambiri kapena kutsekula m'mimba, kapena ngati mwataya madzi ambiri m'thupi lanu ndikumva chizungulire kapena kukomoka. Dokotala wanu angakuuzeni kuti musatenge tolvaptan (Samsca). Dokotala wanu mwina sangakupatseni tolvaptan (Samsca) ngati mulingo wanu wa sodium uyenera kuchulukitsidwa mwachangu kwambiri.
• Uzani dokotala wanu ngati mwakhalapo ndi potaziyamu wambiri m'magazi anu.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga tolvaptan (Samsca), itanani dokotala wanu.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Tolvaptan (Samsca) itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• ludzu
• pakamwa pouma
• pafupipafupi, pokodza kwambiri
• kudzimbidwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

• kusowa chilakolako
• nseru
• kusanza
• malungo
• osamva bwino
• kutopa kapena kufooka kosazolowereka
• kuyabwa
• chikasu cha khungu kapena maso
• mkodzo wakuda
• kupweteka kumtunda chakumanja kwam'mimba
• kutsegula m'mimba
• Kulephera kumwa bwinobwino
• chizungulire
• kukomoka
• masanzi omwe ali magazi kapena amaoneka ngati malo a khofi
• chimbudzi chamagazi kapena chakuda komanso chochedwa
• kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• ming'oma
• zidzolo

Tolvaptan (Samsca) itha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kukodza kwambiri
• ludzu lokwanira
• chizungulire
• kukomoka

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira tolvaptan (Samsca).

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Samsca^®