Jekeseni ya cyclophosphamide

Zamkati

• Asanalandire jekeseni wa cyclophosphamide,
• Cyclophosphamide zingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo izi:

Cyclophosphamide imagwiritsidwa ntchito yokha kapena kuphatikiza mankhwala ena ochizira Hodgkin's lymphoma (matenda a Hodgkin) ndi non-Hodgkin's lymphoma (mitundu ya khansa yomwe imayamba mumtundu wama cell oyera omwe nthawi zambiri amalimbana ndi matenda); T-cell lymphoma (CTCL, khungu la khansa la chitetezo cha mthupi lomwe limayamba kuwoneka ngati zotupa pakhungu); angapo myeloma (mtundu wa khansa ya m'mafupa); ndi mitundu ina ya khansa ya m'magazi (khansa yamagazi oyera), kuphatikiza khansa ya m'magazi (CLL), matenda a khansa ya myelogenous (CML), acute myeloid leukemia (AML, ANLL), ndi acute lymphoblastic leukemia (ALL). Amagwiritsidwanso ntchito pochiza retinoblastoma (khansa m'maso), neuroblastoma (khansa yomwe imayamba m'maselo amitsempha ndipo imachitika makamaka mwa ana), khansara ya ovari (khansa yomwe imayamba m'ziwalo zoberekera zazimayi pomwe mazira amapangidwira), ndi khansa ya m'mawere . Cyclophosphamide imagwiritsidwanso ntchito kuchiza matenda a nephrotic (matenda omwe amayamba chifukwa cha kuwonongeka kwa impso) kwa ana omwe matenda awo sanasinthe, ayamba kukulirakulira, kapena abwerera atalandira mankhwala ena kapena ana omwe adakumana ndi zovuta zina ndi zina mankhwala. Cyclophosphamide ili mgulu la mankhwala otchedwa alkylating agents. Cyclophosphamide ikagwiritsidwa ntchito pochiza khansa, imagwira ntchito pochepetsa kapena kuletsa kukula kwa maselo a khansa mthupi lanu. Pamene cyclophosphamide imagwiritsidwa ntchito pochiza matenda a nephrotic, imagwira ntchito kupondereza chitetezo cha mthupi lanu.

Jekeseni ya cyclophosphamide imabwera ngati ufa woti uwonjezeredwe kumadzimadzi ndikubayidwa kudzera m'mitsempha (mumtsempha) ndi dokotala kapena namwino kuofesi yazachipatala kapena kuchipatala cha odwala kuchipatala. Ikhozanso kulowetsedwa mu mnofu (mu minofu), intraperitoneally (m'mimba), kapena intrapleurally (m'chifuwa). Kutalika kwa chithandizo kumatengera mitundu ya mankhwala omwe mukumwa, momwe thupi lanu limayankhira, ndi mtundu wa khansa kapena momwe muliri.

Dokotala wanu angafunikire kuchedwetsa chithandizo chanu kapena kusintha mlingo wanu ngati mukukumana ndi zovuta zina. Ndikofunika kuti muuze dokotala momwe mukumvera mukamalandira chithandizo cha jekeseni ya cyclophosphamide.

Jekeseni ya cyclophosphamide nthawi zina imagwiritsidwanso ntchito kuthana ndi khansa yamapapo yam'mapapo (kansa yaying'ono yamapapo yam'mapapo; SCLC). Amagwiritsidwanso ntchito pochizira rhabdomyosarcoma (mtundu wa khansa ya minofu) ndi Ewing's sarcoma (mtundu wa khansa ya mafupa) mwa ana. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jekeseni wa cyclophosphamide,

• Uzani dokotala ndi wazamankhwala ngati muli ndi vuto la cyclophosphamide, othandizira ena monga bendamustine (Treanda^®), busulfan (Myerlan^®), Mayambayi^®), carumustine (BiCNU^®, Gliadel^® Kokulumunya), chlorambucil (Leukeran^®), ifosfamide (Ifex^®), lomustine (CeeNU^®), Zolemba (Alkeran^®), procarbazine (Mutalane^®), kapena temozolomide (Temodar^®), mankhwala ena aliwonse, kapena zina zilizonse zopangira jekeseni ya cyclophosphamide. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: allopurinol (Zyloprim^®), cortisone acetate, doxorubicin (Adriamycin^®, Mwayi^®), hydrocortisone (Cortef^®), kapena phenobarbital (Luminal^® Sodium). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi cyclophosphamide, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala ngati munalandirapo mankhwala ndi mankhwala ena a chemotherapy kapena ngati mwalandira x-ray posachedwa. Uzani dokotala wanu ngati mwakhalapo ndi matenda a impso kapena chiwindi.
• muyenera kudziwa kuti cyclophosphamide imatha kusokoneza msambo mwa azimayi ndipo imatha kusiya umuna mwa amuna. Cyclophosphamide ingayambitse kusabereka kwamuyaya (zovuta kukhala ndi pakati); komabe, simuyenera kuganiza kuti simungatenge mimba kapena kuti simungapatse wina mimba. Amayi omwe ali ndi pakati kapena akuyamwitsa ayenera kuuza adokotala asanayambe kulandira mankhwalawa. Simuyenera kukonzekera kukhala ndi ana mukalandira mankhwala a chemotherapy kapena kwakanthawi mutalandira chithandizo. (Lankhulani ndi dokotala wanu kuti mumve zambiri.) Gwiritsani ntchito njira yodalirika yolerera popewa kutenga pakati. Cyclophosphamide ikhoza kuvulaza mwana wosabadwayo.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukulandira jekeseni ya cyclophosphamide.

Imwani madzi ambiri mukamalandira mankhwalawa.

Cyclophosphamide zingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kusowa chilakolako kapena kunenepa
• kupweteka m'mimba
• kutsegula m'mimba
• kutayika tsitsi
• zilonda pakamwa kapena palilime
• kusintha kwa khungu
• kusintha kwa mtundu kapena kukula kwa zala kapena zala zakumiyendo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• zilonda zapakhosi, malungo, kuzizira, kapena zizindikilo zina za matenda
• kuchira kovulaza kapena kosafulumira
• kuvulaza kapena kutuluka mwachilendo
• wakuda, malo odikira
• pokodza kupweteka kapena mkodzo wofiira
• zidzolo
• ming'oma
• kuyabwa
• kuvuta kupuma kapena kumeza
• kupuma movutikira
• chifuwa
• kutupa miyendo, akakolo, kapena mapazi
• kupweteka pachifuwa
• chikasu cha khungu kapena maso

Cyclophosphamide ikhoza kuonjezera chiopsezo choti mungakhale ndi khansa zina. Lankhulani ndi dokotala wanu za kuopsa k kulandira jekeseni wa cyclophosphamide.

Cyclophosphamide zingayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mankhwalawa amasungidwa kuchipatala kapena kuchipatala komwe mumalandira mulingo uliwonse

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• wakuda, malo odikira
• mkodzo wofiira
• kuvulaza kapena kutuluka mwachilendo
• kutopa kapena kufooka kosazolowereka
• zilonda zapakhosi, chifuwa, malungo, kapena zizindikilo zina za matenda
• kutupa miyendo, akakolo, kapena mapazi
• kupweteka pachifuwa

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu limayankhira pa cyclophosphamide.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Cytoxan^® Jekeseni
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