Cabozantinib (khansa ya chithokomiro)

Zamkati

• Musanatenge cabozantinib (Cometriq),
• Cabozantinib (Cometriq) imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo izi:

Cabozantinib (Cometriq) amagwiritsidwa ntchito pochizira mtundu wina wa khansa ya chithokomiro yomwe ikukulirakulira ndipo yafalikira mbali zina za thupi. Cabozantinib (Cometriq) ali mgulu la mankhwala otchedwa tyrosine kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuchepetsa kapena kuletsa kufalikira kwa maselo a khansa.

Cabozantinib imapezekanso ngati piritsi (Cabometyx) yochizira renal cell carcinoma (RCC; mtundu wa khansa womwe umayamba m'maselo a impso) ndi hepatocellular carcinoma (HCC; mtundu wa khansa ya chiwindi) mwa odwala ena anathandizidwa ndi mankhwala ena. Izi zimangopereka chidziwitso chokha chokhudza cabozantinib capsules (Cometriq) cha khansa ya chithokomiro. Ngati mukugwiritsa ntchito mankhwalawa kutsogola kwa RCC kapena HCC, werengani monograph yotchedwa cabozantinib (khansa ya chiwindi ndi impso).

Cabozantinib (Cometriq) amabwera ngati kapisozi woti atenge pakamwa. Amamwa kamodzi patsiku pamimba yopanda kanthu, osachepera ola limodzi musanadye ndi maola awiri mutadya. Tengani cabozantinib (Cometriq) mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani cabozantinib (Cometriq) ndendende monga momwe auzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza makapisozi lonse ndi galasi (8 ma ola, 240 mL) madzi. Osatsegula.

Dokotala wanu akhoza kuchepetsa kuchuluka kwa cabozantinib (Cometriq) kapena kuyimitsa kwanthawi zonse kapena kwakanthawi mankhwala anu mukakumana ndi zovuta zina. Onetsetsani kuti mwalankhula ndi dokotala momwe mumamvera mukamalandira cabozantinib (Cometriq).

Kutalika kwa chithandizo chanu kumadalira momwe mumayankhira mankhwalawo ndi zotsatirapo zomwe mumakumana nazo. Pitirizani kutenga cabozantinib (Cometriq) ngakhale mukumva bwino. Osasiya kumwa cabozantinib (Cometriq) osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge cabozantinib (Cometriq),

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la cabozantinib (Cabometyx, Cometriq), mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a cabozantinib. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: adefovir (Hepsera); antifungals monga itraconazole (Sporanox), ketoconazole, ndi voriconazole (Vfend); clarithromycin (Biaxin, mu Prevpac); dexamethasone; furosemide (Lasix); mankhwala ena a HIV kapena Edzi monga abacavir (Ziagen), atazanavir (Reyataz), cidofovir, indinavir (Crixivan), lamivudine (Epivir, ku Combivir); nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ku Kaletra), saquinavir (Invirase), ndi tenofovir (Viread); mankhwala ena ogwidwa monga carbamazepine (Equetro, Tegretol, Teril), phenobarbital, ndi phenytoin (Dilantin, Phenytek); nefazodone; probenecid (Probalan), rifabutin (Mycobutin); rifampin (Rifactin, Rifadin, ku Rifamate, ku Rifater); rifapentine (Priftin); telithromycin (Ketek); ndi warfarin (Coumadin, Jantoven). Mankhwala ena ambiri amathanso kulumikizana ndi cabozantinib (Cometriq), onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala pazotsatira.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• uzani dokotala wanu ngati mwangotuluka kumene mwachilendo kapena koopsa monga kutsokomola magazi, kusanza magazi, kapena mipando yamagazi kapena yakuda. Komanso muuzeni dokotala ngati muli ndi bala lotseguka kapena lochiritsa, kapena ngati mwakhalapo ndi matenda othamanga magazi kapena matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kuyezetsa mimba musanayambe mankhwala ndi cabozantinib. Simuyenera kutenga pakati mukamamwa ndi cabozantinib komanso kwa miyezi 4 mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito mukamachiza. Mukakhala ndi pakati mukatenga cabozantinib (Cometriq), itanani dokotala wanu mwachangu. Cabozantinib itha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Dokotala wanu angakuuzeni kuti musamamwe mkaka mukamamwa mankhwala komanso kwa miyezi 4 mutatha kumwa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito cabozantinib (Cometriq).
• ngati mukuchitidwa opaleshoni, uzani dokotala kapena dokotala kuti mukumwa cabozantinib (Cometriq). Dokotala wanu angakuuzeni kuti musiye kumwa cabozantinib (Cometriq) masiku osachepera 21 musanachite opareshoni ndipo adzakuwuzani nthawi yomwe muyenera kuyambiranso kumwa mankhwala mukatha opaleshoni.
• muyenera kudziwa kuti cabozantinib (Cometriq) itha kubweretsa mavuto akulu ndi nsagwada. Dokotala wa mano ayenera kufufuza mano anu musanayambe kumwa cabozantinib komanso nthawi zonse mukamamwa mankhwala. Onetsetsani kutsuka mano ndikutsuka mkamwa mwanu moyenera mukamamwa cabozantinib (Cometriq). Lankhulani ndi dokotala musanalandire chithandizo chilichonse cha mano mukamamwa mankhwalawa. Dokotala wanu angakuuzeni kuti musiye kumwa cabozantinib masiku osachepera 21 musanachite opaleshoni yamano.
• muyenera kudziwa kuti kuthamanga kwa magazi kwanu kumatha kukulira mukamalandira cabozantinib (Cometriq). Dokotala wanu angayang'anire kuthamanga kwa magazi anu mukamalandira chithandizo.

Musamamwe madzi amphesa kapena kudya zipatso zamphesa kapena zakudya zilizonse kapena zowonjezera zomwe zili ndi zipatso zamphesa kapena madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ndi ochepera maola 12 mpaka muyeso wanu wotsatira, tulukani mlingo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Cabozantinib (Cometriq) imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kudzimbidwa
• zotupa m'mimba
• nseru
• kusanza
• kutentha pa chifuwa
• kusintha kwa kulawa chakudya
• zovuta kumeza
• kufiira, kutupa, zilonda, kapena kupweteka mkamwa kapena kukhosi
• kusowa chilakolako
• kuonda
• kutopa kapena kufooka
• kupweteka m'malo olumikizirana mafupa
• kupweteka kwa minofu kapena kupuma
• nkhawa
• dzanzi, kutentha, kapena kumva kulasalasa m'manja, mikono, mapazi, kapena miyendo
• khungu lowuma
• khungu lolimba
• kutayika tsitsi
• mtundu wa tsitsi umayamba kuwalira kapena kutuwa
• mawu amasintha kapena kukodola

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kutsokomola magazi kapena magazi aundana
• kusanza komwe ndi kwamagazi kapena kumawoneka ngati malo a khofi
• Kutuluka magazi msambo kolemera kuposa masiku onse
• ofiira kapena akuda, chembetsani chopondapo
• Kutuluka magazi kosazolowereka kapena kopweteka
• kutsegula m'mimba
• malo ofewa kapena opweteka m'mimba
• kutupa kapena kupweteka m'manja kapena m'miyendo
• kupuma movutikira
• kupusa kapena kukomoka
• thukuta
• dzanzi kapena kufooka kwa nkhope, mkono, kapena mwendo mbali imodzi ya thupi lanu
• chizungulire
• zovuta mwadzidzidzi moyenera kapena mogwirizana
• Matama otupa kapena opweteka
• mwadzidzidzi, mutu wopweteka kwambiri
• kupweteka kwa nsagwada
• Dzino likundiwawa
• kugwidwa
• kuyenda mwadzidzidzi
• mavuto masomphenya mwadzidzidzi
• chisokonezo
• zovuta mwadzidzidzi kuganiza kapena kulankhula bwino
• zidzolo
• kufiira, kupweteka, kutupa, kapena kuphulika pamanja kapena pansi
• kuvuta kudya kapena kumwa chifukwa cha zilonda mkamwa kapena kunyansidwa ndi kusanza

Cabozantinib (Cometriq) imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira.http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kuiwalika
• chisokonezo
• kuonda

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti awone kuyankha kwa thupi lanu ku cabozantinib (Cometriq).

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Komala^®