Mipomersen jekeseni

Zamkati

• Musanafike jekeseni wa mipomersen,
• Jekeseni wa Mipomersen itha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Jekeseni wa Mipomersen itha kuwononga chiwindi. Uzani dokotala wanu ngati mumamwa kapena mumamwa mowa wambiri komanso ngati mwakhalapo ndi matenda a chiwindi, kuphatikizapo kuwonongeka kwa chiwindi komwe kumachitika mukamamwa mankhwala ena. Dokotala wanu angakuuzeni kuti musagwiritse ntchito jekeseni ya mipomersen ngati muli ndi matenda a chiwindi. Uzani dokotala wanu komanso wamankhwala ngati mumamwa acetaminophen (Tylenol, ndi mankhwala ena opweteka) komanso ngati mukumwa amiodarone (Cordarone, Pacerone); mankhwala ena a cholesterol wambiri; methotrexate (Rheumatrex, Trexall); tamoxifen (Soltamox); kapena mankhwala a tetracycline monga doxycycline (Doryx, Vibra-Tabs, Vibramycin), minocycline (Dynacin, Minocin), ndi tetracycline (Sumycin). Ngati mukumane ndi izi, itanani dokotala wanu msanga: nseru, kusanza, kusowa chilakolako, kupweteka m'mimba, kutopa kwambiri, chikasu cha khungu kapena maso, mkodzo wamdima, kapena kuyabwa.

Kumwa mowa kumawonjezera chiopsezo choti chiwindi chanu chitha kuwonongeka mukamalandira jekeseni wa mipomersen. Musamwe zakumwa zoledzeretsa zoposa kamodzi patsiku mukamamwa mankhwalawa.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo kuti muwone kuyankha kwa thupi lanu ku jakisoni wa mipomersen.

Chifukwa chowopsa pachiwindi, pulogalamu yakhazikitsidwa kuti iziyang'anira odwala omwe ali ndi jakisoni wa mipomersen. Dokotala wanu adzafunika kumaliza maphunziro ake ndikulembetsa nawo pulogalamuyi asanakupatseni mankhwalawa. Mutha kulandila mankhwala anu ku pharmacy yomwe yatsimikiziridwa kuti izitulutsa jekeseni wa mipomersen. Funsani dokotala wanu kuti mumve zambiri za momwe mungapezere mankhwala anu.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jekeseni ya mipomersen ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito jakisoni wa mipomersen.

Jekeseni wa Mipomersen imagwiritsidwa ntchito pochepetsa cholesterol ndi zinthu zina zamafuta m'magazi mwa anthu omwe ali ndi homozygous family hypercholesterolemia (HoFH; cholowa chosowa kwambiri chomwe chimayambitsa cholesterol yambiri m'magazi, ndikuwonjezera chiopsezo cha matenda amtima). Anthu ena omwe ali ndi HoFH amatha kuchiritsidwa ndi LDL apheresis (njira yomwe imachotsa LDL m'magazi), koma jakisoni wa mipomersen sayenera kugwiritsidwa ntchito limodzi ndi mankhwalawa. Jekeseni wa Mipomersen sayenera kugwiritsidwa ntchito pochepetsa mafuta m'thupi mwa anthu omwe alibe HoFH. Jekeseni wa Mipomersen ili mgulu la mankhwala otchedwa antisense oligonucleotide (ASO) inhibitors. Zimagwira ntchito poletsa mafuta kuti asapangike mthupi.

Jekeseni wa Mipomersen imabwera ngati yankho lobaya pansi pa khungu. Nthawi zambiri amabayidwa kamodzi pamlungu. Jekeseni jekeseni wa mipomersen tsiku lomwelo la sabata komanso nthawi yofanana tsiku lililonse mukamubaya. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Gwiritsani ntchito jakisoni wa mipomersen monga momwe mwalamulira. Osabaya jakisoni wochulukirapo kapena kumubaya nthawi zambiri kuposa momwe adanenera.

Jekeseni wa Mipomersen itha kuthandizira kuchepetsa mafuta m'thupi koma sichithandiza matenda anu. Zitha kutenga miyezi 6 kapena kupitilira apo kuti cholesterol yanu ichepe kwambiri. Pitirizani kugwiritsa ntchito jakisoni wa mipomersen ngakhale mukumva bwino. Osasiya kugwiritsa ntchito jakisoni wa mipomersen osalankhula ndi dokotala.

Mutha kudzibaya jekeseni wa mipomersen nokha kapena kukhala ndi mnzanu kapena wachibale kudzakubayirani mankhwalawo. Dokotala wanu akuwonetsani inu kapena munthu yemwe ati adzalandire mankhwalawo momwe angaperekere jakisoni. Inu ndi munthu amene mudzalandire mankhwalawa muyenera kuwerenga malangizo a omwe akupanga omwe amabwera ndi mankhwalawo. Funsani dokotala ngati muli ndi funso kapena simukumvetsetsa momwe mungabayire mipomersen.

Jekeseni Mipomersen amabwera mu syringe pre-wodzazidwa ndi Mbale. Ngati mukugwiritsa ntchito mbale za jakisoni wa mipomersen, dokotala wanu angakuuzeni mtundu wa syringe yomwe muyenera kugwiritsa ntchito komanso momwe mungatengere mankhwalawo mu syringe. Osasakaniza mankhwala ena aliwonse m'jekeseni ndi jekeseni ya mipomersen.

Tengani jekeseni wa mipomersen mufiriji osachepera mphindi 30 musanakonze jekeseni wake kuti mankhwala azitha kutentha. Sungani syringe m'matumba ake kuti muteteze ku kuwala panthawiyi. Osayesa kutenthetsa sirinjiyo powotenthetsa mwanjira iliyonse.

Nthawi zonse muziyang'ana jekeseni wa mipomersen musanaibayire. Onetsetsani kuti zolembedwazo zimasindikizidwa, osasinthidwa ndipo zilembedwe ndi dzina lolondola la mankhwala ndi tsiku lotha ntchito lomwe silinadutse. Onetsetsani kuti yankho mu botolo kapena syringe ndilowoneka bwino komanso lopanda utoto kapena wachikasu pang'ono. Musagwiritse ntchito vial kapena syringe ngati yawonongeka, yatha ntchito, yopaka utoto, kapena mitambo kapena ngati ili ndi tinthu tina.

Mutha kubaya mipomersen paliponse kunja kwa mikono yanu, ntchafu zanu, kapena mimba yanu, kupatula mchombo wanu (batani lamimba) ndi dera lomwe lili mainchesi awiri mozungulira iwo. Sankhani malo osiyana nthawi iliyonse mukabaya mankhwala. Osabaya khungu lofiyira, lotupa, lomwe lili ndi kachilombo, lipsera, lolemba mphini, lotenthedwa ndi dzuwa kapena lomwe limakhudzidwa ndi zotupa kapena matenda apakhungu monga psoriasis.

Sirinji kapena botolo lililonse lodzaza kale limangokhala ndi jakisoni wokwanira wa mipomersen pamlingo umodzi. Osayesa kugwiritsa ntchito mbale kapena ma syringe kangapo. Tayani masirinji ogwiritsidwa ntchito m'chidebe chosagwira. Funsani dokotala wanu kapena wamankhwala momwe mungatherere chidebe chosagwira mankhwala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanafike jekeseni wa mipomersen,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi mipomersen, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jekeseni ya mipomersen. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo mankhwala omwe atchulidwa mgulu la CHENJEZO LOFUNIKA. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• osabaya mankhwala ena aliwonse nthawi yomweyo kuti mubayire mipomersen. Funsani dokotala wanu kapena wamankhwala nthawi yoti amulowetse mankhwala anu.
• uzani dokotala wanu ngati mwakhalapo ndi matenda a impso.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Muyenera kugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamalandira chithandizo. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukamalandira chithandizo, siyani kugwiritsa ntchito jakisoni wa mipomersen ndipo itanani dokotala nthawi yomweyo.

Idyani chakudya chochepa cha mafuta, cholesterol. Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Mutha kuchezanso tsamba la National Cholesterol Education Program (NCEP) ku http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf kuti mumve zambiri za zakudya.

Ngati mukukumbukira masiku osachepera atatu isanakwane mlingo wanu wotsatira, tengani mlingo womwe mwaphonya nthawi yomweyo. Komabe, ngati mukukumbukira masiku ochepera atatu isanakwane tsiku lanu lotsatira, tulukani mlingo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Osabaya jakisoni kawiri kuti mupange yomwe mwaphonya.

Jekeseni wa Mipomersen itha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kufiira, kupweteka, kukoma mtima, kutupa, kusintha kwa khungu, kuyabwa, kapena kuphwanya khungu komwe mudabaya mipomersen
• zizindikiro ngati chimfine monga kutentha thupi, kuzizira, kupweteka kwa minofu, kupweteka kwa mafupa, kufooka, ndi kutopa zomwe zimachitika masiku awiri oyamba mutabaya jekeseni mipomersen
• mutu
• kuvuta kugona kapena kugona
• kupweteka kwa mikono kapena miyendo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kupweteka pachifuwa
• kugunda kwamtima
• kutupa kwa mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
• zidzolo
• ming'oma
• kutupa kwa nkhope, mmero, lilime, milomo, kapena maso
• ukali
• zovuta kumeza kapena kupuma

Jekeseni wa Mipomersen itha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mu firiji ndikuteteza ku kuwala. Ngati mulibe firiji, mutha kusunga mankhwalawo kutentha kwa masiku 14.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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