Alirocumab jekeseni

Zamkati

• Musanagwiritse ntchito jakisoni wa alirocumab,
• Alirocumab jekeseni imatha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kugwiritsa ntchito jakisoni wa alirocumab ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

Alirocumab jekeseni imagwiritsidwa ntchito limodzi ndi zakudya, zokha kapena kuphatikiza mankhwala ena ochepetsa mafuta m'thupi (HMG-CoA reductase inhibitors [statins] kapena ezetimibe [Zetia, ku Liptruzet, ku Vytorin]), mwa achikulire omwe ali ndi heterozygous hypercholesterolemia (cholowa chololedwa momwe cholesterol sichingachotsedwere m'thupi nthawi zonse) kuti ichepetse kuchuluka kwa mafuta otsika kwambiri a lipoprotein (LDL) cholesterol ('cholesterol choyipa') m'magazi. Alirocumab jekeseni imagwiritsidwanso ntchito kwa achikulire omwe ali ndi matenda amtima kuti achepetse chiwopsezo cha kupwetekedwa mtima, matenda amtima, kapena kupweteka pachifuwa kapena koopsa pachifuwa. Alirocumab jakisoni ali mgulu la mankhwala otchedwa proprotein convertase subtilisin kexin mtundu 9 (PCSK9) inhibitor monoclonal antibodies. Zimagwira ntchito poletsa kutulutsa kwa cholesterol ya LDL mthupi motero kumachepetsa kuchuluka kwa cholesterol yomwe ingakule pamakoma a mitsempha.

Kuwonjezeka kwa cholesterol m'mbali mwa mitsempha yanu (njira yotchedwa atherosclerosis) kumachepetsa kutuluka kwa magazi, chifukwa chake, mpweya umapereka mtima wanu, ubongo, ndi ziwalo zina za thupi lanu.

Jakisoni wa Alirocumab umadza ngati yankho (madzi) mu jakisoni woyikidwa kale ndi cholembera chofikira kale kuti abayire subcutaneously (pansi pa khungu) kamodzi pamasabata awiri kapena anayi. Gwiritsani ntchito jakisoni wa alirocumab mozungulira nthawi yomweyo milungu iwiri kapena inayi iliyonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Gwiritsani ntchito jakisoni wa alirocumab ndendende momwe mwalangizira. Musagwiritse ntchito mankhwala ochepa kapena ochepa kapena kuwagwiritsa ntchito nthawi zambiri kapena kwa nthawi yayitali kuposa momwe adalangizira dokotala.

Pambuyo pa masabata 4 mpaka 8 a chithandizo, dokotala wanu akhoza kukulitsa mlingo wanu kutengera momwe mumayankhira mankhwalawa.

Jakisoni wa Alirocumab umathandiza kuchepetsa mafuta m'thupi, koma sachiza izi. Pitirizani kugwiritsa ntchito jakisoni wa alirocumab ngakhale mukumva bwino. Osasiya kugwiritsa ntchito jakisoni wa alirocumab osalankhula ndi dokotala.

Jakisoni wa Alirocumab umabwera m'makola oyikiramo omwe ali ndimankhwala oyambira omwe ali ndi mankhwala okwanira mlingo umodzi. Ngati dokotala angakuuzeni kuti muyenera kugwiritsa ntchito cholembera kapena jakisoni wopitilira muyeso wanu, gwiritsani ntchito zolembera kapena ma syringe pambuyo pake m'malo osiyanasiyana a jakisoni. Zitha kutenga masekondi 20 kuti mulowetse mankhwalawa. Nthawi zonse jekeseni alirocumab mu cholembera chake choyambirira kapena jakisoni; osazisakaniza ndi mankhwala ena aliwonse. Kutaya singano zogwiritsidwa ntchito, ma syringe, ndi zida mu chidebe chosagwira; osagwiritsanso ntchito cholembera kapena syringe. Lankhulani ndi dokotala wanu kapena wamankhwala za momwe mungatayire chidebe chosagwira mankhwala.

Mutha kubaya jakisoni wa alirocumab ntchafu yanu, mikono yanu, kapena m'mimba, kupatula gawo lamasentimita awiri mozungulira mchombo wanu (batani lamimba) komanso pafupi ndi m'chiuno mwanu. Gwiritsani ntchito malo osiyana jekeseni iliyonse. Osalowetsa malo omwe khungu limapweteka, lofiira, lophwanyidwa, lotupa, lotenthedwa ndi dzuwa, lolimba, lotentha, lotenga kachilombo, kapena lovulala mwanjira iliyonse kapena m'malo omwe ali ndi mitsempha, zipsera, zotupa, kapena zotambalala.

Werengani mosamala malangizo a wopanga kuti agwiritse ntchito omwe amabwera ndi mankhwala. Malangizowa amafotokoza momwe mungabayire jakisoni wa alirocumab. Onetsetsani kuti mufunse wamankhwala kapena dokotala ngati muli ndi mafunso aliwonse amomwe mungapangire mankhwalawa.

Chotsani jakisoni woyikiratu kapena cholembera chofiyira choyambirira kuchokera mufiriji ndikulola kuti zizitha kutentha kwa mphindi 30 kapena 40 musanagwiritse ntchito. Musayike jakisoni woyambirira kapena cholembera chofiyira kumbuyo mufiriji ikatenthetsedwa kutentha.

Musanagwiritse ntchito jakisoni wa alirocumab, yang'anani yankho mu syringe kapena cholembera choyambirira. Mankhwalawa ayenera kukhala owoneka achikaso otumbululuka komanso opanda tinthu tating'onoting'ono. Musagwedezeke jakisoni woyambira kapena cholembera cha dosing wokhala ndi jakisoni wa alirocumab.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jakisoni wa alirocumab,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la jakisoni wa alirocumab, mankhwala aliwonse, kapena china chilichonse mu jakisoni wa alirocumab. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni dokotala ngati mwakhalapo kapena munakhalapo ndi matenda aliwonse.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa alirocumab, itanani dokotala wanu.

Idyani chakudya chochepa cha mafuta, cholesterol. Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Mutha kuchezanso tsamba la National Cholesterol Education Program (NCEP) kuti mumve zambiri za zakudya pa: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Mukabaya jakisoni wa alirocumab milungu iwiri iliyonse, jekeseni jakisoni wa alirocumab mukangokumbukira ngati ali mkati mwa masiku asanu ndi awiri a mlingo womwe mwaphonya ndikuyambiranso dongosolo lanu loyambirira. Komabe, ngati mwatenga nthawi yayitali kuposa masiku 7 kuchokera pa mlingo womwe mwaphonya, tulukani mlingo uwu, ndikudikirira mpaka mulingo womwe mudzakonzekere.

Mukabaya jakisoni wa alirocumab pakatha milungu inayi iliyonse, jekeseni jakisoni wa alirocumab mukangokumbukira ngati ali mkati mwa masiku asanu ndi awiri a mlingo womwe mwaphonya ndikuyambiranso dongosolo lanu loyambirira. Ngati kwadutsa masiku 7 kuchokera pa mlingo wosowa, ndiye jekeseni mlingo ndikuyamba ndandanda yatsopano yamasabata 4 kutengera tsikuli.

Osabaya jakisoni kawiri kuti mupange mlingo womwe umasowa. Itanani dokotala wanu ngati mwaphonya mlingo ndikukhala ndi mafunso pazomwe mungachite.

Alirocumab jekeseni imatha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kufiira, kuyabwa, kutupa, kupweteka, kapena kukoma pamalo obayira
• Zizindikiro za chimfine, malungo, mutu, kuzizira

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kugwiritsa ntchito jakisoni wa alirocumab ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

• kuyabwa
• zidzolo
• ming'oma
• kuvuta kupuma kapena kumeza
• kutupa kwa nkhope, mmero, lilime, milomo, ndi maso

Alirocumab jekeseni imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani m'firiji, koma osazizira. Jakisoni wa Alirocumab amathanso kusungidwa kutentha mpaka madigiri 77 F (25 madigiri C) mu katoni yoyambirira mpaka masiku 30. Pambuyo masiku 30, alirocumab iyenera kuponyedwa kutali. Sungani jakisoni wa alirocumab kutetezedwa ku kuwala mu katoni yoyambirira.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu limayankhira jakisoni wa alirocumab.

Musalole kuti wina aliyense agwiritse ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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