Spironolactone

Zamkati

• Musanatenge spironolactone,
• Spironolactone ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo izi:

Spironolactone yadzetsa zotupa mu nyama zasayansi. Lankhulani ndi dokotala wanu za kuopsa ndi ubwino wogwiritsa ntchito mankhwalawa chifukwa cha matenda anu.

Spironolactone imagwiritsidwa ntchito pochiza odwala ena omwe ali ndi hyperaldosteronism (thupi limatulutsa aldosterone yambiri, mahomoni obwera mwachilengedwe); misinkhu potaziyamu otsika; mtima kulephera; ndi odwala omwe ali ndi edema (kusungidwa kwamadzimadzi) komwe kumachitika chifukwa cha zinthu zosiyanasiyana, kuphatikiza chiwindi, kapena matenda a impso. Amagwiritsidwanso ntchito payekha kapena ndi mankhwala ena kuti athetse kuthamanga kwa magazi. Spironolactone ali mgulu la mankhwala otchedwa aldosterone receptor antagonists. Zimapangitsa impso kuchotsa madzi osafunikira ndi sodium kuchokera mthupi kupita mumkodzo koma zimachepetsa kutayika kwa potaziyamu mthupi.

Kuthamanga kwa magazi ndizofala ndipo ngati sanalandire chithandizo, kumatha kuwononga ubongo, mtima, mitsempha, impso ndi ziwalo zina za thupi. Kuwonongeka kwa ziwalozi kumatha kuyambitsa matenda amtima, matenda amtima, kulephera kwa mtima, sitiroko, impso kulephera, kusawona bwino, ndi mavuto ena. Kuphatikiza pa kumwa mankhwala, kusintha moyo wanu kumathandizanso kuchepetsa kuthamanga kwa magazi. Zosinthazi zikuphatikiza kudya zakudya zopanda mafuta ambiri komanso mchere, kukhalabe ndi thanzi labwino, kuchita masewera olimbitsa thupi osachepera mphindi 30 masiku ambiri, osasuta, komanso kumwa mowa pang'ono.

Spironolactone imabwera ngati piritsi ndikuyimitsidwa (madzi; Carospir) kuti atenge pakamwa. Nthawi zambiri amatengedwa kamodzi kapena kawiri patsiku. Tengani kuyimitsidwa kwa spironolactone nthawi zonse kaya ndi chakudya kapena popanda chakudya nthawi iliyonse. Tengani spironolactone mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani spironolactone ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Sambani kuyimitsidwa pakamwa musanagwiritse ntchito kusakaniza mankhwala mofanana.

Dokotala wanu akhoza kukuyambitsani pamlingo wochepa wa spironolactone ndipo pang'onopang'ono muwonjezere mlingo wanu.

Mapiritsi a Spironolactone ndikuyimitsidwa kumatulutsa mankhwala mosiyanasiyana mthupi lanu ndipo sangasinthane wina ndi mnzake. Ingotengani mankhwala a spironolactone omwe adakupatsani dokotala ndipo musasinthire kuzinthu zina za spironolactone pokhapokha dokotala atakuuzani kuti muyenera kutero.

Spironolactone imayang'anira kuthamanga kwa magazi, edema, kulephera kwa mtima, ndi hyperaldosteronism koma sichichiritsa izi. Zitha kutenga milungu iwiri kapena kupitilira apo kuti spironolactone isachitike. Pitirizani kumwa spironolactone ngakhale mukumva bwino. Osasiya kumwa spironolactone osalankhula ndi dokotala.

Spironolactone imagwiritsidwanso ntchito limodzi ndi mankhwala ena pochiza kutha msinkhu (zomwe zimapangitsa ana kutha msinkhu posachedwa, zomwe zimapangitsa kukula kwa zikhalidwe zogonana mwa atsikana omwe amakhala ochepera zaka 8 komanso anyamata amakhala ochepera zaka 9. ) kapena myasthenia gravis (MG, matenda omwe misempha sagwira ntchito moyenera ndipo odwala amatha kufooka; kufooka, kutayika kwa kulumikizana kwa minofu; ndi mavuto a masomphenya, malankhulidwe, ndi chikhodzodzo). Spironolactone itha kugwiritsidwanso ntchito kuchiritsa odwala ena azimayi okhala ndi tsitsi lachilendo. Lankhulani ndi dokotala wanu za kuopsa kokugwiritsa ntchito mankhwalawa.

Mankhwalawa nthawi zina amapatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge spironolactone,

• auzeni dokotala ndi wazamankhwala ngati muli ndi vuto la spironolactone; mankhwala ena aliwonse; kapena chilichonse chophatikizira m'mapiritsi a spironolactone. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu ngati mukumwa eplerenone (Inspra). Dokotala wanu angakuuzeni kuti musamwe spironolactone ngati mukumwa mankhwalawa.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: aminoglycoside maantibayotiki monga amikacin, gentamicin, kanamycin, neomycin (Neo-Rx, Neo-Fradin), streptomycin, ndi tobramycin (Tobi); ma angiotensin otembenuza enzyme (ACE) zoletsa monga benazepril (Lotensin, ku Lotrel), captopril (Capoten), enalapril (Vasotec), fosinopril, lisinopril (ku Prinzide, mu Zestoretic), moexipril (Univasc, in Unoptic) Aceon), quinapril (Accupril, mu Accuretic, mu Quinaretic), ramipril (Altace), ndi trandolapril (Mavik, ku Tarka); Otsutsana ndi angiotensin II (angiotensin receptor blockers; ARBs) monga azilsartan (Edarbi, Edarbyclor), candesartan (Atacand, ku Atacand HCT), eprosartan (Teveten, ku Teveten HCT), irbesartan (Avapro, ku Avalide), losartan (Cozaar Hyzaar), olmesartan (Benicar, ku Azor, Benicar HCT, Tribenzor), telmisartan (Micardis, ku Micardis HCT), ndi valsartan (Diovan, ku Diovan HCT, Exforge); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDS) monga ibuprofen (Advil, Motrin), indomethacin (Indocin, Tivorbex), ndi naproxen (Aleve, Naprosyn); barbiturates monga phenobarbital; cholestyramine (Prevalite); cisplatin; digoxin (Lanoxin); okodzetsa ('mapiritsi amadzi') kuphatikiza okodzetsa osapulumutsa potaziyamu monga amiloride (Midamor) ndi triamterene (Dyrenium, ku Dyazide, ku Maxzide); heparin kapena otsika-maselo-heparin enoxaparin (Lovenox); lifiyamu (Lithobid); mankhwala ochizira kuthamanga kwa magazi; mankhwala osokoneza bongo opweteka; oral steroids monga dexamethasone, methylprednisolone (Medrol), ndi prednisone (Rayos); zowonjezera potaziyamu; ndi trimethoprim (Primsol, ku Bactrim).
• auzeni dokotala ngati muli ndi matenda a Addison kapena matenda ena omwe angayambitse potaziyamu, kapena matenda a impso. Dokotala wanu angakuuzeni kuti musatenge spironolactone.
• uzani dokotala wanu ngati muli ndi matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, kapena konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga spironolactone, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa spironolactone.
• muyenera kudziwa kuti kumwa mowa ndi mankhwalawa kumatha kuyambitsa chizungulire, kupepuka mutu, komanso kukomoka mukaimirira mwachangu pamalo abodza. Lankhulani ndi dokotala wanu zakumwa mowa mukamamwa spironolactone.

Tsatirani malangizo a dokotala pazakudya zanu, kuphatikiza upangiri wa zakudya zochepetsedwa mchere (sodium) komanso pulogalamu yazolimbitsa thupi tsiku lililonse. Pewani pothetsera mchere wokhala ndi potaziyamu mukamamwa mankhwalawa. Lankhulani ndi dokotala wanu za kuchuluka kwa zakudya za potaziyamu (mwachitsanzo, nthochi, prunes, zoumba, ndi madzi a lalanje) zomwe mungakhale nazo pazakudya zanu.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wanu wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Spironolactone ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kusanza
• kutsegula m'mimba
• kupweteka m'mimba kapena kukokana
• kukulitsa kapena kupweteka mabere mwa amuna kapena akazi
• kusamba kosasamba
• Kutuluka magazi kumaliseche atatha msambo ('pambuyo pa kusintha kwa moyo', kutha kwa msambo wamwezi uliwonse) akazi
• Kuvuta kusunga kapena kukwaniritsa erection
• kuzama kwa mawu
• kukulitsa kukula kwa tsitsi mbali zina za thupi
• Kusinza
• kutopa
• kusakhazikika

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• kufooka kwa minofu, kupweteka, kapena kukokana
• kupweteka, kuwotcha, kuchita dzanzi, kapena kumva kupweteka m'manja kapena m'mapazi
• kulephera kusuntha mikono kapena miyendo
• kusintha kwa kugunda kwa mtima
• chisokonezo
• nseru
• kutopa kwambiri
• pakamwa pouma, ludzu, chizungulire, kusakhazikika, kupweteka mutu, kapena zizindikiro zina za kuchepa kwa madzi m'thupi
• kutuluka mwachilendo kapena kuphwanya
• kusowa mphamvu
• kusowa chilakolako
• kupweteka kumtunda chakumanja kwam'mimba
• chikasu cha khungu kapena maso
• zizindikiro ngati chimfine
• zidzolo
• ming'oma
• kuyabwa
• kuvuta kupuma kapena kumeza
• kusanza magazi
• magazi m'mipando
• kuchepa pokodza
• kukomoka

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe munabwera, chatsekedwa mwamphamvu, komanso kuti ana asafikire. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• Kusinza
• chisokonezo
• zidzolo
• nseru
• kusanza
• chizungulire
• kutsegula m'mimba
• kumva kulira kwa mikono ndi miyendo
• kutayika kwa minofu
• kufooka kapena kulemera kwa miyendo
• kugunda kosasinthasintha kapena kosachedwa

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu limayankhira pa spironolactone.

Musanapite kukayezetsa labotale, uzani adotolo ndi omwe akuwagwiritsa ntchito kuti mukupanga spironolactone.

Musalole kuti wina aliyense amwe mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Aldactone^®
• Zamgululi^®