Simvastatin
Zamkati
- Musanatenge simvastatin,
- Simvastatin itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala mwadzidzidzi.
Simvastatin imagwiritsidwa ntchito limodzi ndi zakudya, kuwonda, komanso kuchita masewera olimbitsa thupi kuti muchepetse chiopsezo cha mtima komanso kupwetekedwa mtima komanso kuchepetsa mwayi woti kuchitidwa opaleshoni yamtima kwa anthu omwe ali ndi matenda amtima kapena omwe ali pachiwopsezo chodwala matenda amtima. Simvastatin imagwiritsidwanso ntchito kuchepetsa kuchuluka kwa zinthu zamafuta monga low-density lipoprotein (LDL) cholesterol ('' cholesterol yoyipa '') ndi triglycerides m'magazi ndikuwonjezera kuchuluka kwa cholesterol-lipoprotein (HDL) (' 'cholesterol wabwino') m'magazi. Simvastatin itha kugwiritsidwanso ntchito kuchepetsa kuchuluka kwa cholesterol ndi zinthu zina zamafuta m'magazi mwa ana ndi achinyamata azaka 10 mpaka 17 zakubadwa omwe ali ndi mabanja heterozygous hypercholesterolemia (mkhalidwe wobadwa nawo womwe cholesterol sichitha kuchotsedwa mthupi nthawi zonse).Simvastatin ali mgulu la mankhwala otchedwa HMG-CoA reductase inhibitors (ma statins). Zimagwira pochepetsa kuchepa kwa cholesterol m'thupi kuti muchepetse kuchuluka kwa mafuta m'thupi omwe angakule pamakoma a mitsempha ndikuletsa magazi kupita kumtima, ubongo, ndi ziwalo zina za thupi.
Kuwonjezeka kwa cholesterol ndi mafuta m'mbali mwa mitsempha yanu (njira yotchedwa atherosclerosis) imachepetsa kutuluka kwa magazi, chifukwa chake, mpweya umapatsa mtima wanu, ubongo, ndi ziwalo zina za thupi lanu. Kutsitsa cholesterol yanu yamafuta ndi mafuta ndi simvastatin kwawonetsedwa kuti kumateteza matenda amtima, angina (kupweteka pachifuwa), zilonda, ndi matenda amtima.
Simvastatin imabwera ngati piritsi komanso kuyimitsidwa pakamwa. Mapiritsiwa amatengedwa kamodzi patsiku madzulo. Kuyimitsidwa kumatengedwa kamodzi patsiku madzulo pamimba yopanda kanthu. Tengani simvastatin mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani simvastatin chimodzimodzi monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.
Sakanizani kuyimitsidwa bwino kwa masekondi 20 musanagwiritse ntchito.
Ngati mutenga kuyimitsidwa kwa simvastatin, musagwiritse ntchito supuni ya tiyi ya banja kuti muyese mlingo wanu. Masipuni apanyumba si zida zoyezera molondola, ndipo mutha kulandira mankhwala ochulukirapo kapena osakwanira mukayesa mlingo wanu ndi supuni ya tiyi ya banja. M'malo mwake, gwiritsani ntchito choyezera chodziwika bwino monga supuni ya mankhwala kapena syringe yapakamwa. Funsani dokotala wanu kapena wamankhwala ngati mukufuna thandizo kupeza kapena kugwiritsa ntchito chida choyezera.
Dokotala wanu akhoza kukuyambitsani pamlingo wochepa wa simvastatin ndikuwonjezera pang'onopang'ono, osapitilira kamodzi pakatha milungu inayi.
Pitilizani kutenga simvastatin ngakhale mukumva bwino. Osasiya kumwa simvastatin osalankhula ndi dokotala.
Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.
Musanatenge simvastatin,
- uzani adotolo ndi wazamankhwala ngati simukugwirizana ndi simvastatin, mankhwala aliwonse, kapena chilichonse chosakaniza m'mapiritsi a simvastatin kapena kuyimitsidwa pakamwa. Funsani dokotala wanu kapena wamankhwala mndandanda wa zosakaniza.
- uzani dokotala wanu ngati mukumwa mankhwala oletsa mafungal monga itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil) ndi voriconazole (Vfend); clarithromycin (Biaxin, mu Prevpac); mankhwala okhala ndi cobicistat (Stribild); cyclosporine (Gengraf, Neoral, Sandimmune); danazol; erythromycin (EES, E-Mycin, Erythrocin); gemfibrozil (Lopid); HIV protease inhibitors monga atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (ku Kaletra), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), saquinavir (Invirase) nsonga (Aptivus); nefazodone; telaprevir (Incivek); ndi telithromycin (Ketek). Dokotala wanu angakuuzeni kuti musamwe simvastatin ngati mukumwa mankhwalawa.
- Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: amiodarone (Cordarone, Pacerone); amlodipine (Norvasc, ku Caduet, ku Lotrel); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); colchicine (Colcrys); digoxin (Digitek, Lanoxicaps, Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac); dronearone (Multaq); mankhwala ena ochepetsa mafuta m'thupi monga fenofibrate (Tricor), lomitapide (Juxtapid), ndi niacin (nicotinic acid, Niacor, Niaspan); ranolazine (Ranexa); ndi verapamil (Calan, Covera, Isoptin, Verelan). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena amathanso kulumikizana ndi simvastatin, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
- uzani dokotala wanu ngati muli ndi matenda a chiwindi. Dokotala wanu adzaitanitsa mayeso a magazi kuti awone momwe chiwindi chanu chikugwirira ntchito ngakhale simukuganiza kuti muli ndi matenda a chiwindi. Dokotala wanu angakuuzeni kuti musatenge simvastatin ngati muli ndi matenda a chiwindi kapena ngati mayesero akuwonetsa kuti mwina mukudwala matenda a chiwindi.
- uzani dokotala ngati mumamwa mowa wopitilira awiri patsiku, ngati muli ndi zaka 65 kapena kupitilira apo, kapena ngati ndinu aku Asia, makamaka ngati ndinu achi China. Muuzeni dokotala ngati mwakhalapo ndi vuto la chithokomiro, matenda a shuga, khunyu, kupweteka kwa minofu kapena kufooka, kuthamanga kwa magazi, kapena matenda a impso.
- Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Simuyenera kutenga pakati mukamamwa mankhwala a simvastatin. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukamamwa simvastatin, siyani kumwa simvastatin ndipo itanani dokotala wanu mwachangu. Simvastatin imatha kuvulaza mwana wosabadwayo.
- Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa simvastatin.
- ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa simvastatin. Ngati mwagonekedwa mchipatala chifukwa chovulala kwambiri kapena matenda, uzani dokotala yemwe amakuthandizani kuti mukumwa simvastatin.
- Funsani adotolo za zakumwa zoledzeretsa pamene mukumwa simvastatin. Mowa ungapangitse kuti pakhale zovuta zoyipa.
Idyani chakudya chochepa cha mafuta, cholesterol. Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Mutha kuchezanso tsamba la National Cholesterol Education Program (NCEP) kuti mumve zambiri za zakudya pa http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.
Pewani kumwa madzi amphesa mukamamwa simvastatin.
Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.
Simvastatin itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- kudzimbidwa
- kupweteka m'mimba
- nseru
- mutu
- kuiwala kapena kuyiwala
- chisokonezo
- khungu loyera kapena lofiira
Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala mwadzidzidzi.
- kupweteka kwa minofu, kufooka, kapena kufooka komwe kulibe malungo kapena kusowa mphamvu
- mkodzo wofiira wakuda
- kuchepa pokodza
- kusowa mphamvu, kutopa, kapena kufooka
- kusowa chilakolako
- kupweteka kumtunda chakumanja kwam'mimba
- chikasu cha khungu kapena maso
- mkodzo wachikuda
- malungo kapena kuzizira
- kuchapa
- matuza
- zidzolo
- ming'oma
- kuyabwa
- kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
- kuvuta kupuma kapena kumeza
- ukali
- kupweteka pamodzi
- kutengeka ndi kuwala
Mankhwalawa amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.
Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).
Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mapiritsi kutentha kwa firiji komanso kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Sungani kuyimitsidwa kutentha. Osazizira kapena kuyimitsa firiji. Onetsetsani kuti mugwiritse ntchito kuyimitsidwa pasanathe masiku 30 mutatsegula botolo ndikutaya mankhwala aliwonse omwe atsala pambuyo pa masiku 30.
Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org
Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.
Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.
Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena a labu mukamalandira chithandizo, makamaka mukayamba kuwonetsa chiwindi.
Musanayezetsedwe labotale, uzani adotolo ndi ogwira nawo ntchito kuti mukumwa simvastatin.
Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.
Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.
- Flolipid®
- Zocor®
- Wachinyamata® (yokhala ndi Simvastatin, Sitagliptin)¶
- Simcor® (yokhala ndi Niacin, Simvastatin)
- Vytorin® (munali Ezetimibe, Simvastatin)
¶ Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.
Idasinthidwa Komaliza - 01/15/2020