Kodi insulinoma, zizindikiro zazikulu ndi chithandizo

Zamkati

• Zizindikiro zazikulu
• Momwe matendawa amapangidwira
• Njira zothandizira
• 1. Opaleshoni
• 2. Mankhwala a mahomoni ndi oyang'anira insulini
• 3. Chemotherapy
• 4. Kuchotsa magazi ndi kuponderezana kwapakati
• Zomwe zingayambitse

Insulinoma, yomwe imadziwikanso kuti islet cell tumor, ndi mtundu wa chotupa m'mapapo, oopsa kapena owopsa, omwe amatulutsa insulin yochulukirapo, ndikupangitsa magazi m'magazi kuchepa, ndikupanga hypoglycemia. Zizindikiro zomwe zimayambitsa chotupacho zitha kukhala chizungulire, kusokonezeka m'maganizo, kunjenjemera ndikusintha kwamalingaliro ndipo zimachitika chifukwa cha kuchepa kwa magazi m'magazi.

Kuzindikira kwa insulinoma kumapangidwa ndi endocrinologist kapena oncologist kudzera m'mayeso amwazi, monga kusala kudya kwa glucose ndi kujambula, komwe kumatha kuwerengedwa ngati tomography, kujambula kwa maginito kapena kuwunikira ziweto, ndipo chithandizo choyenera kwambiri ndi opaleshoni, mahomoni amankhwala ndikuwongolera magazi shuga, komanso chemotherapy, ablation kapena embolization.

Zizindikiro zazikulu

Insulinoma ndi mtundu wa chotupa chomwe chimapezeka m'mankhwala omwe amasintha magazi m'magazi ndipo, chifukwa chake, zizindikilo zazikulu zimakhudzana ndi kuchepetsa shuga m'magazi, wotchedwa hypoglycemia, monga:

• Maso kapena masomphenya awiri;
• Kusokonezeka maganizo;
• Chizungulire;
• Kumva kufooka;
• Kupsa mtima kwambiri;
• Khalidwe limasintha;
• Kukomoka;
• Thukuta lozizira kwambiri.

Nthawi zovuta kwambiri, insulinoma ikapita patsogolo kwambiri ndipo imakhudza ziwalo zina za thupi, monga chiwindi, ubongo ndi impso, zizindikilo monga kugwidwa, kugunda kwa mtima, kutaya chidziwitso, kukomoka ndi jaundice zitha kuwoneka. Phunzirani zambiri za jaundice ndi momwe mungazindikire.

Momwe matendawa amapangidwira

Kupezeka kwa insulinoma kumachitika kudzera m'mayeso amwazi, omwe amayenera kuchitidwa mopanda kanthu, kuti azindikire kuchuluka kwa shuga ndi insulin m'magazi ndipo, makamaka, kuchuluka kwa shuga kumakhala kotsika ndipo milingo ya insulin ndiyokwera. Onani momwe kuyezetsa magazi m'magazi kwachangu kumachitidwira komanso momwe zimayendera.

Kuti mudziwe malo enieni, kukula ndi mtundu wa chotupacho m'mapapo ndi kuwona ngati insulinoma yafalikira mbali zina za thupi, kuyerekezera kuyerekezera monga computed tomography, magnetic resonance imaging kapena pet scan kumawonetsedwa ndi endocrinologist kapena oncologist.

Nthawi zina, adokotala amatha kuyitanitsa mayeso ena kuti akwaniritse matendawa ndikudziwa kukula kwa chotupacho monga endoscopy, chomwe chimagwiritsidwa ntchito kuwunika ngati chotupacho chafika mkatikati mwa m'mimba kapena m'matumbo, ndi arteriography, yomwe imadziwika magazi akuyenda m'mapiko.

Njira zothandizira

Insulinoma ndi mtundu wa chotupa m'mapapo, chomwe chimatha kukhala chosaopsa kapena choyipa, chomwe chimayambitsa kusintha kwa magazi m'magazi, ndipo ngati atachiritsidwa msanga amatha kuchiritsidwa. Chithandizo cha matenda amtunduwu chikuwonetsedwa ndi oncologist ndipo zimatengera malo, kukula ndi gawo la chotupacho, komanso kupezeka kwa metastases, ndipo kungalimbikitsidwe:

1. Opaleshoni

Kuchita opaleshoni ndiyo njira yabwino kwambiri yothandizira insulinoma, komabe, ngati chotupa m'mapapo ndi chachikulu kwambiri, chafalikira mbali zina za thupi kapena munthuyo ali ndi thanzi lofooka, adotolo sangakulimbikitseni kuchitidwa opaleshoni. Ngati opareshoni yachitika, wodwalayo angafunikire kugwiritsa ntchito ngalande yotchedwa penrose, kuti athetse madzi omwe amadzaza pakuchita opaleshoni. Onani zambiri momwe mungasamalire ngalande mukatha opaleshoni.

2. Mankhwala a mahomoni ndi oyang'anira insulini

Mankhwala ena amatha kugwiritsidwa ntchito pochiza insulinoma, monga mankhwala omwe amachepetsa kapena kuchepetsa kupangika kwa mahomoni omwe amakulitsa chotupacho, monga somatostatin analogues, wotchedwa octreotide ndi lanreotide.

Mankhwala ena omwe amawonetsedwa pochiza matenda amtunduwu ndi mankhwala omwe amathandiza kuchepetsa kuchuluka kwa insulin m'magazi, kupewa kuchepa kwa shuga. Kuphatikiza apo, chakudya chambiri chokhala ndi shuga wambiri chimatha kupangidwira kuti milingo ya shuga izikhala yabwinobwino.

3. Chemotherapy

Chemotherapy ikulimbikitsidwa ndi oncologist kuti ichiritse insulinoma ndi metastasis ndipo imakhala ndi kugwiritsa ntchito mankhwala mu mtsempha kuti iwononge maselo osadziwika, omwe amatsogolera kukula kwa chotupacho, komanso kuchuluka kwa magawo ndi mtundu wa mankhwala omwe ayenera kukhala ntchito zimadalira mikhalidwe ya matenda, monga kukula ndi malo.

Komabe, mankhwala omwe amagwiritsidwa ntchito kuthetsa ma celloma a insulinoma ndi doxorubicin, fluorouracil, temozolomide, cisplatin ndi etoposide. Mankhwalawa nthawi zambiri amaperekedwa mu seramu, kudzera mu catheter mumitsempha ndipo, nthawi zina, angagwiritse ntchito yopitilira imodzi, kutengera ndondomeko yomwe dokotala adakhazikitsa.

4. Kuchotsa magazi ndi kuponderezana kwapakati

Kuchotsa ma radiofrequency ndi mtundu wa mankhwala omwe amagwiritsa ntchito kutentha, opangidwa ndi mafunde a wailesi, kupha ma celloma a insulinoma ndipo ndioyenera kuthana ndi zotupa zazing'ono zomwe sizifalikira mbali zina za thupi.

Mofananamo ndi kuchotsa, kusungunuka kwamitsempha ndi njira yotetezeka komanso yochepa, yolimbikitsidwa ndi oncologist kuti ichiritse insulinomas yaying'ono ndikuphatikizira kugwiritsa ntchito madzi ena, kudzera mu catheter, kutseka kutuluka kwa magazi pachotupacho, kuthandizira kuthetsa maselo omwe ali ndi matenda .

Zomwe zingayambitse

Zomwe zimayambitsa insulinoma sizinafotokozeredwe bwino, koma zimakonda kukulira mwa amayi kuposa amuna, mwa anthu azaka zapakati pa 40 ndi 60 komanso omwe ali ndi matenda amtundu wina monga mtundu 1 neurofibromatosis kapena tuberous sclerosis. Dziwani zambiri za tuberous sclerosis ndi momwe amachiritsidwira.

Kuphatikiza apo, kukhala ndi matenda ena monga endocrine neoplasia, komwe kumayambitsa kukula kachilendo kwa maselo am'magazi a endocrine, ndi matenda a Von Hippel-Lindau, omwe amabadwa nawo ndipo amatsogolera kuwonekera kwa zotupa m'thupi lonse, atha kuwonjezera mwayi woti awonekere insulinoma .