Zotupa za m'mimba mwa Stromal Tumors: Zizindikiro, Zomwe Zimayambitsa, ndi Zowopsa

Zamkati

• Zizindikiro
• Zoyambitsa
• Zowopsa
• Zaka
• Chibadwa

Zotupa za m'mimba (GISTs) ndi zotupa, kapena masango amitundu yochulukirachulukira, m'matumba am'mimba (GI). Zizindikiro za zotupa za GIST ndi izi:

• mipando yamagazi
• kupweteka kapena kusapeza pamimba
• nseru ndi kusanza
• kulepheretsa matumbo
• misa pamimba yomwe mungamve
• kutopa kapena kumva kutopa kwambiri
• Kumva kukhuta kwambiri mutadya pang'ono
• kupweteka kapena kuvutika mukameza

Thirakiti la GI ndi dongosolo lomwe limayang'anira kugaya ndi kuyamwa chakudya ndi michere. Zimaphatikizanso pamimba, m'mimba, m'matumbo ang'ono, ndi m'matumbo.

Ma GIST amayamba m'maselo apadera omwe ali gawo la dongosolo lodziyimira pawokha. Maselowa ali pakhoma la thirakiti la GI, ndipo amayendetsa kayendedwe ka minofu kuti chimbudzi chigwere.

Ambiri mwa ma GIST amapangidwa m'mimba. Nthawi zina amapangidwa m'matumbo ang'onoang'ono, koma ma GIST omwe amapangidwa m'matumbo, m'mimba, ndi m'matumbo amakhala ocheperako. Gists amatha kukhala owopsa komanso khansa kapena owopsa osati khansa.

Zizindikiro

Zizindikirozo zimadalira kukula kwa chotupacho komanso komwe chimapezeka. Chifukwa cha izi, nthawi zambiri amasiyana molimba komanso kuchokera kwa munthu wina ndi mnzake. Zizindikiro monga kupweteka m'mimba, nseru, ndi kutopa zimakumana ndimatenda ena ambiri.

Ngati mukukumana ndi izi kapena zina mwazizindikiro, muyenera kulankhula ndi dokotala. Adzakuthandizani kudziwa zomwe zimayambitsa matenda anu.

Ngati muli ndi zoopsa zilizonse za GIST kapena vuto lina lililonse lomwe lingayambitse izi, onetsetsani kuti mwamuuza dokotala wanu.

Zoyambitsa

Zomwe zimayambitsa GISTs sizikudziwika, ngakhale zikuwoneka kuti pali ubale pakusintha pamawonedwe a protein ya KIT. Khansa imayamba m'maselo akamayamba kukula. Maselowo akamakulirakulira mosatonthozeka, amapangika ndikupanga misa yotchedwa chotupa.

Ma GIST amayamba mu thirakiti la GI ndipo amatha kukula mpaka kumagulu kapena ziwalo zapafupi. Nthawi zambiri zimafalikira ku chiwindi ndi peritoneum (kumimba kwa m'mimba) koma kawirikawiri kumafupa apafupi.

Zowopsa

Pali zifukwa zochepa chabe zodziwika za chiopsezo cha GIST:

Zaka

M'badwo wofala kwambiri wopanga GIST uli pakati pa 50 ndi 80. Ngakhale ma GIST amatha kuchitika mwa anthu ochepera zaka 40, ndizosowa kwambiri.

Chibadwa

Zambiri za GIST zimachitika mosasintha ndipo zilibe chifukwa chomveka. Komabe, anthu ena amabadwa ali ndi kusintha kwa majini komwe kumatha kubweretsa ku GISTs.

Zina mwa majini ndi mikhalidwe yokhudzana ndi GIST ndi monga:

Neurofibromatosis 1: Matendawa, omwe amatchedwanso kuti Von Recklinghausen's (VRD), amayamba chifukwa cha vuto la Zamgululi jini. Vutoli limatha kupitilizidwa kuchokera kwa kholo kupita kwa mwana koma silimabadwa nthawi zonse. Anthu omwe ali ndi vutoli ali pachiwopsezo chowonjezeka chotupa chotupa m'mitsempha ali aang'ono. Zotupa izi zimatha kuyambitsa mabala akhungu pakhungu ndikudumphadumpha m'miyendo kapena m'manja. Vutoli limakulitsanso mwayi wakukula kwa GIST.

Wodziwika bwino m'mimba wam'mimba chotupa chotupa: Matendawa amayamba chifukwa cha jini lachilendo la KIT lomwe limadutsa kuchokera kwa kholo kupita kwa mwana. Izi zosowa zimawonjezera chiopsezo cha ma GIST. Ma GIST awa amatha kupanga ali ocheperako kuposa anthu wamba. Anthu omwe ali ndi vutoli atha kukhala ndi ma GIST angapo m'moyo wawo.

Kusintha kwa majini a succinate dehydrogenase (SDH): Anthu omwe amabadwa ndikusintha kwamtundu wa SDHB ndi SDHC ali pachiwopsezo chowonjezeka chokhala ndi GIST. Alinso pachiwopsezo chachikulu chotenga mtundu wa chotupa cha mitsempha chotchedwa paraganglioma.