Zomwe Ndidapeza Mayeso a Alzheimer's

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Asayansi ali pafupi kwambiri kupanga mayeso a magazi omwe adzatha kuzindikira matenda a Alzheimer zaka khumi asanazindikire, malinga ndi lipoti la FASEB Journal. Koma ndi mankhwala ochepa opewera kupezeka, kodi mungafune kudziwa? Ichi ndichifukwa chake mayi wina anati inde.

Mayi anga anamwalira ndi matenda a Alzheimer mu 2011, pamene anali ndi milungu ingapo kuti akwanitse zaka 87. Anandiuzapo kuti anali ndi azakhali awo amene anamwaliranso ndi matenda a Alzheimer, ndipo ngakhale sindingathe kunena motsimikiza ngati zimenezi n’zoona. ndinakumana ndi azakhali awa, ndipo nthawi imeneyo, matenda omveka bwino anali ovuta kupeza kuposa masiku ano), podziwa kuti mbiri ya banja ili yandilimbikitsa kuti ndidziwe zambiri. (Kodi matenda a Alzheimer's ndi Okalamba?)

Ndidagwiritsa ntchito 23andme [ntchito yowunikira malovu kunyumba yomwe idaletsedwa ndi FDA podikirira kuyesedwa kwina], yomwe imayesa, mwa zina, kuwopsa kwa Alzheimer's. Nditapita kukawona zotsatira zanga pa intaneti, tsambalo lidafunsa, "Mukutsimikiza kuti mukufuna kupita patsamba lino?" Nditadina inde akuti, ngati, "Mukutsimikiza?" Chifukwa chake panali mwayi wosiyanasiyana wosankha, "Mwina sindikufuna kudziwa izi." Ndinangopitirira kudina inde; Ndinali wamanjenje, koma ndimadziwa kuti ndikufuna kudziwa zoopsa zanga.

23andme anandiuza kuti ndili ndi 15 peresenti ya mwayi wokhala ndi Alzheimer's poyerekeza ndi chiopsezo cha munthu wamba, chomwe ndi 7 peresenti. Chifukwa chake kumvetsetsa kwanga ndikuti chiwopsezo changa chimakhala chokwera kawiri. Ndinayesera kutenga izi ngati chidziwitso-osatinso zina.

Ndinalowamo ndikudziwa kuti padzakhala mwayi wabwino kwambiri kuti ziwopsezo zanga zitha kukhala zapamwamba kuposa pafupifupi, chifukwa chake ndinali wokonzeka m'maganizo. Sindinadabwe, ndipo sindinatayike. Moona mtima, ndinkakhazika mtima pansi kuti sizinanene kuti chiwopsezo changa chinali 70 peresenti.

Nditazindikira kuti ndili pachiwopsezo kuchokera ku 23andme, ndidalankhula ndi womenyera ufulu wanga pazotsatira zanga. Anandipatsa chidziwitso chofunikira kwambiri: Chifukwa choti muli ndi chiopsezo cha majini, sikunaperekedwe kuti mudzadwala. Sizili ngati [matenda amtundu wa neurodegenerative genetic] a Huntington, komwe ngati muli ndi jini ndikukhala ndi moyo wazaka 40, mumatsimikiza kuti mwalandira. Ndi Alzheimer's, sitikudziwa. (Onetsetsani kuti mukuwerenga momwe Phunziro Latsopano Losautsa Limaunikira pa Ubongo Wodabwitsa.)

Sindinachite chilichonse pazotsatira zanga, potengera kusintha kwamachitidwe. Kunena zowona, sindikudziwa kuti pali zambiri zomwe tingachite panobe. Amayi anga anali kuyenda kwambiri, anali wokangalika, anali wokonda kucheza nawo - zinthu zonsezi akatswiri amati ndizothandiza kwambiri muubongo wanu - ndipo adakhalabe ndi Alzheimer's.

Amayi anga anayamba kuchepa mphamvu kwinakwake pafupi ndi zaka 83. Koma izi zikutanthauza kuti anali ndi zaka zoposa 80 zabwino kwambiri. Akadakhala kuti anali wonenepa kwambiri, osakonda kucheza nawo, kapena kudya zakudya zosapatsa thanzi, mwina jini ija ikadalowa ali ndi zaka 70, ndani akudziwa? Chifukwa chake pakadali pano, malingaliro ambiri ndikuchita zomwe mungathe kuti mupewe kudwala matendawa. Kupatulapo, ndizomwe zili pachiwopsezo choyambitsa matenda a Alzheimer's. [Kusinthaku, komwe kumakhudza anthu ochepera zaka 65, kuli ndi chiyanjano chotsimikizika cha majini.]

Ndikumva anthu omwe akunena kuti sakufuna kudziwa. Koma ndinali ndi zinthu ziwiri m'maganizo: Ndinkafuna kudziwa zomwe zingakhalepo makolo anga kuwonjezera pa matenda a Alzheimer's, chifukwa ndilibe chidziwitso chambiri chokhudza mbiri yaumoyo ya agogo anga. Ndipo zaka 5 kapena 10 kuchokera pano, ngati tidziwa zambiri za jini yomwe tiyenera kuyang'ana kapena zolembera zomwe tiyenera kuyang'ana, ndili ndi kuyerekezera. Ndili ndi momwe ziriri pano. (Pezani Zakudya zabwino kwambiri zopewera matenda a Alzheimer's.)

Ndikudziwa kuti zotsatirazi ndizomwe zimangotengera kuti ndili pachiwopsezo. Sindikudandaula za zotsatira zanga, chifukwa ndikudziwa kuti kuyesa majini ndi gawo limodzi chabe la chithunzi chachikulu. Ndimachita gawo langa lokhazikika, kucheza ndi anthu, kudya moyenera - ndipo zina zonse zachoka m'manja mwanga.

Koma ndikusangalalabe kuti sananene 70 peresenti.

Amayi ake atamwalira, Elaine adalemba buku lonena za zomwe amayi ake adakumana nazo ndi matendawa komanso momwe adasamalirira. Thandizani Elaine kuthandiza ena pogula; gawo lina lazopeza limapita ku kafukufuku wa Alzheimer's.

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