ACTH kuyezetsa magazi

Mayeso a ACTH amayesa kuchuluka kwa adrenocorticotropic hormone (ACTH) m'magazi. ACTH ndi timadzi tomwe timatuluka mu ubongo wa pituitary.

Muyenera kuyesa magazi.

Dokotala wanu angakufunseni kuti muyesedwe m'mawa kwambiri. Izi ndizofunikira, chifukwa kuchuluka kwa cortisol kumasiyanasiyana tsiku lonse.

Muthanso kuuzidwa kuti musiye kumwa mankhwala omwe angakhudze zotsatira za mayeso. Mankhwalawa amaphatikizapo glucocorticoids monga prednisone, hydrocortisone, kapena dexamethasone. (Osayimitsa mankhwalawa pokhapokha atakulangizani ndi omwe amakupatsani.)

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kubaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka kapena kuvulala pang'ono. Izi posachedwa zichoka.

Ntchito yayikulu ya ACTH ndikuwongolera glucocorticoid (steroid) hormone cortisol. Cortisol imatulutsidwa ndi adrenal gland. Amayendetsa kuthamanga kwa magazi, shuga wamagazi, chitetezo chamthupi komanso mayankho kupsinjika.

Kuyesaku kungathandize kupeza zomwe zimayambitsa zovuta zina za mahomoni.

Zomwe zimakhalapo poyeserera magazi m'mawa kwambiri ndi 9 mpaka 52 pg / mL (2 mpaka 11 pmol / L).

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyana kapena amatha kuyesa mitundu yosiyanasiyana. Lankhulani ndi dokotala wanu tanthauzo la zotsatira zanu zoyesa.

Mulingo wapamwamba kwambiri kuposa wabwinobwino wa ACTH ungasonyeze:

• Matenda a Adrenal samatulutsa cortisol yokwanira (Matenda a Addison)
• Matenda a Adrenal osatulutsa mahomoni okwanira (kobadwa nako adrenal hyperplasia)
• Chimodzi kapena zingapo zamatenda a endocrine ndizogwira ntchito kwambiri kapena apanga chotupa (angapo endocrine neoplasia mtundu I)
• Pituitary ikupanga ACTH (Cushing matenda), yomwe nthawi zambiri imayamba chifukwa cha chotupa chosakhala ndi khansa pamatenda am'mimba
• Mtundu wambiri wa chotupa (mapapo, chithokomiro, kapena kapamba) wopanga kwambiri ACTH (ectopic Cushing syndrome)

Mulingo wotsika kuposa wabwinobwino wa ACTH ungasonyeze:

• Mankhwala a Glucocorticoid akupondereza kupanga kwa ACTH (kofala kwambiri)
• Matenda a pituitary samatulutsa mahomoni okwanira, monga ACTH (hypopituitarism)
• Chotupa cha adrenal gland chomwe chimatulutsa cortisol wambiri

Pali chiopsezo chochepa chotenga magazi anu. Mitsempha ndi mitsempha imasiyana mosiyanasiyana kuchokera pa munthu wina kupita kwina komanso kuchokera mbali imodzi ya thupi kupita mbali inayo. Kutenga magazi kuchokera kwa anthu ena kumatha kukhala kovuta kuposa ena.

Zowopsa zina zomwe zimakhudzidwa ndikutengedwa magazi ndizochepa koma mwina ndi izi:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Ma punctures angapo kuti mupeze mitsempha
• Hematoma (magazi akuchuluka pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Seramu adrenocorticotropic timadzi; Timadzi Adrenocorticotropic; ACTH yovuta kwambiri

• Matenda a Endocrine

Chernecky CC, Berger BJ. Adrenocorticotropic hormone (ACTH, corticotropin) - seramu. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 107.

Melmed S, Kleinberg D. Maselo a pituitary ndi zotupa. Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, olemba. Buku la Williams la Endocrinology. Wolemba 13. Philadelphia, PA: Elsevier; 2016: chap 9.

Stewart PM, Newell-Price JDC. Kachilombo kotchedwa adrenal cortex. Mu: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, olemba. Buku la Williams la Endocrinology. Wolemba 13. Philadelphia, PA: Elsevier; 2016: chap 15.