Tolbutamide

Zamkati

• Musanamwe tolbutamide,
• Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.
• Tolbutamide itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo zizindikiro za hypoglycemia komanso izi:

Tolbutamide imagwiritsidwa ntchito limodzi ndi zakudya komanso masewera olimbitsa thupi, ndipo nthawi zina ndi mankhwala ena, kuchiza matenda ashuga amtundu wa 2 (momwe thupi siligwiritsa ntchito insulini mwachizolowezi, chifukwa chake, silingathe kuwongolera kuchuluka kwa shuga m'magazi). Tolbutamide ali mgulu la mankhwala otchedwa sulfonylureas. Tolbutamide imachepetsa shuga wamagazi popangitsa kuti kapamba apange insulin (chinthu chachilengedwe chomwe chimafunikira kuwononga shuga m'thupi) ndikuthandizira thupi kugwiritsa ntchito insulini moyenera. Mankhwalawa amangothandiza kuchepetsa shuga m'magazi mwa anthu omwe matupi awo amapanga insulin mwachilengedwe. Tolbutamide sagwiritsidwa ntchito pochiza matenda ashuga amtundu wa 1 (momwe thupi silimatulutsira insulin motero, silingathe kuwongolera kuchuluka kwa shuga m'magazi) kapena matenda ashuga ketoacidosis (vuto lalikulu lomwe lingachitike ngati shuga wa magazi sakuchiritsidwa ).

Popita nthawi, anthu omwe ali ndi matenda ashuga komanso shuga wambiri m'magazi amatha kukhala ndi mavuto owopsa kapena owopsa, kuphatikizapo matenda amtima, sitiroko, mavuto a impso, kuwonongeka kwa mitsempha, komanso mavuto amaso. Kumwa mankhwala (mankhwala), kusintha moyo wanu (mwachitsanzo, zakudya, kuchita masewera olimbitsa thupi, kusiya kusuta), komanso kuwunika shuga wanu wamagazi pafupipafupi kungakuthandizeni kuthana ndi matenda anu ashuga komanso kukhala ndi thanzi labwino. Mankhwalawa amathanso kuchepetsa mwayi wokhala ndi vuto la mtima, sitiroko, kapena zovuta zina zokhudzana ndi matenda ashuga monga impso kulephera, kuwonongeka kwamitsempha (dzanzi, miyendo yozizira kapena mapazi; kuchepa kwa kugonana kwa amuna ndi akazi), mavuto amaso, kuphatikiza kusintha kutaya masomphenya, kapena matenda a chiseyeye. Dokotala wanu ndi ena othandizira zaumoyo adzakambirana nanu za njira yabwino yothetsera matenda anu ashuga.

Tolbutamide imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku m'mawa. Uzani dokotala wanu ngati tolbutamide ikukhumudwitsa m'mimba mwanu. Dokotala wanu angakuwuzeni kuti muzimwa mankhwala ochepa a tolbutamide kangapo patsiku. Kukuthandizani kukumbukira kukumbukira kutenga tolbutamide, imwani nthawi yofanana tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani tolbutamide ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu angayambe ndi mlingo wochepa wa tolbutamide ndipo pang'onopang'ono muwonjezere mlingo wanu ngati pakufunika kutero. Mutamwa tolbutamide kwakanthawi, tolbutamide silingathe kuyendetsa shuga wamagazi komanso momwe idapangira koyambirira kwa chithandizo chanu. Dokotala wanu amatha kusintha mlingo wa mankhwala anu ngati mukufunikira kuti mankhwalawa azikugwirirani ntchito bwino. Onetsetsani kuti muuze dokotala momwe mukumvera komanso ngati zotsatira za mayeso anu a shuga akhala apamwamba kapena ocheperapo kuposa nthawi zonse mukamalandira chithandizo.

Mankhwalawa nthawi zina amapatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanamwe tolbutamide,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la tolbutamide, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu tolbutamide. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula ma anticoagulants ('magazi opopera magazi') monga warfarin (Coumadin); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) ndi naproxen (Aleve, Naprosyn); zotchinga beta monga atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), ndi propranolol (Inderal); calcium blockers monga amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, ena), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisold Sular), ndi verapamil (Calan, Isoptin, Verelan); mankhwala enaake; okodzetsa ('mapiritsi amadzi'); fluconazole (Diflucan), mankhwala obwezeretsa mahomoni ndi njira zolerera za mahomoni (mapiritsi oletsa kubereka, zigamba, mphete, zopangira, ndi jakisoni); insulin kapena mankhwala ena ochiza shuga kapena magazi ashuga; isoniazid (INH); MaO inhibitors monga isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ndi tranylcypromine (Parnate); mankhwala a mphumu ndi chimfine; mankhwala a matenda amisala ndi nseru; miconazole (Monistat); kachilombo; mankhwala amlomo monga dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), ndi prednisone (Deltasone); phenytoin (Dilantin); ma probenecid (Benemid); kupweteka kwa salicylate kumachepetsa monga choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, ena), ndi salsalate (Argesic, Disalcid, Salgesic); mankhwala a sulfa monga co-trimoxazole (Bactrim, Septra); sulfasalazine (Azulfidine); ndi mankhwala a chithokomiro. Onetsetsani kuti muwauze adotolo kapena asayansi mukasiya kumwa mankhwala aliwonse mukamwa tolbutamide. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati muli ndi vuto la G6PD (cholowa chomwe chimayambitsa kuwonongeka msanga kwa maselo ofiira kapena kuchepa kwa magazi m'thupi); ngati muli ndi vuto la mahomoni okhudzana ndi adrenal, pituitary, kapena chithokomiro; kapena ngati muli ndi matenda a mtima, impso, kapena chiwindi.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga tolbutamide, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa tolbutamide.
• Funsani dokotala wanu za zakumwa zoledzeretsa pamene mukumwa tolbutamide. Mowa umatha kupangitsa zotsatira zoyipa kuchokera ku tolbutamide kukulira. Kumwa mowa mukumwa tolbutamide kungayambitsenso zizindikiro monga kutsuka (kufiira nkhope), kupweteka mutu, nseru, kusanza, kupweteka pachifuwa, kufooka, kusawona bwino, kusokonezeka m'maganizo, kutuluka thukuta, kutsamwa, kupuma movutikira, komanso nkhawa.
• konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Tolbutamide imatha kupangitsa khungu lanu kuzindikira kuwala kwa dzuwa.
• funsani dokotala wanu choti muchite mukadwala, mutenga matenda kapena malungo, mukumva kupsinjika kwachilendo, kapena mukavulala. Izi zimatha kukhudza shuga wamagazi ndi kuchuluka kwa tolbutamide komwe mungafune.

Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Ndikofunika kudya chakudya chopatsa thanzi, kuchita masewera olimbitsa thupi nthawi zonse, komanso kuonda ngati kuli kofunikira.

Musanayambe kumwa tolbutamide, funsani dokotala zomwe muyenera kuchita mukaiwala kumwa mankhwala. Lembani malangizo awa kuti muthe kuwawunikiranso mtsogolo.

Monga mwalamulo, tengani mlingo womwe mwaphonya mukangokumbukira. Ngati ili pafupi nthawi ya mlingo wotsatira, tambani mlingo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.

Tolbutamide itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• chidzalo chapamwamba m'mimba
• kutentha pa chifuwa
• zidzolo
• mutu
• kusintha kwa kukoma

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• chikasu cha khungu kapena maso
• mipando yoyera
• mkodzo wakuda
• kupweteka kumtunda chakumanja kwam'mimba
• kuvulaza kapena kutuluka mwachilendo
• kutsegula m'mimba
• malungo
• chikhure

Tolbutamide imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Pakafukufuku wina, anthu omwe amamwa tolbutamide kuchiza matenda awo ashuga amatha kufa ndi mavuto amtima kuposa omwe amathandizidwa ndi insulin komanso kusintha kwa zakudya. Lankhulani ndi dokotala wanu za kuopsa kwa kumwa tolbutamide.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri, ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo zizindikiro za hypoglycemia komanso izi:

• kugwidwa
• kutaya chidziwitso

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Magazi anu a shuga ndi mkodzo amayenera kuwunikidwa pafupipafupi kuti mudziwe momwe mungayankhire tolbutamide. Dokotala wanu amatha kuyitanitsa mayeso ena a labu, kuphatikiza glycosylated hemoglobin (HbA1c), kuti muwone kuyankha kwanu ku tolbutamide. Dokotala wanu adzakuwuzani momwe mungayang'anire kuyankha kwanu ndi mankhwalawa poyeza magazi kapena mkodzo wanu shuga kunyumba. Tsatirani malangizowa mosamala.

Musanayezetsedwe kwa labotale, auzeni adotolo ndi ogwira nawo ntchito kuti mukumwa tolbutamide.

Muyenera kuvala chibangili chizindikiritso cha ashuga kuti mutsimikizire kuti mumalandira chithandizo chadzidzidzi pakagwa mwadzidzidzi.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Orinase^®¶

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