PTEN Mayeso Achibadwa

Zamkati

• Kodi kuyesa kwa majini a PTEN ndi chiyani?
• Amagwiritsidwa ntchito yanji?
• Chifukwa chiyani ndikufunika kuyesedwa kwa majini a PTEN?
• Kodi chimachitika ndi chiyani poyesa majini a PTEN?
• Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?
• Kodi pali zoopsa zilizonse pamayeso?
• Kodi zotsatirazi zikutanthauza chiyani?
• Kodi pali china chilichonse chomwe ndiyenera kudziwa chokhudza kuyesedwa kwa majini a PTEN?
• Zolemba

Kodi kuyesa kwa majini a PTEN ndi chiyani?

Kuyesedwa kwa majini a PTEN kumayang'ana kusintha, kotchedwa kusintha, mu jini yotchedwa PTEN. Chibadwa ndiye gawo lobadwa kuchokera kwa amayi ndi abambo ako.

Jini ya PTEN imathandizira kuletsa kukula kwa zotupa. Amadziwika kuti suppressor ya chotupa. Jini lopondereza chotupa lili ngati mabuleki pagalimoto. Imaika "mabuleki" m'maselo, kuti asagawane mwachangu kwambiri. Ngati muli ndi kusintha kwa majini a PTEN, kumatha kuyambitsa kukula kwa zotupa zopanda khansa zotchedwa hamartomas. Hamartomas amatha kuwonekera mthupi lonse. Kusinthaku kumathandizanso kukulitsa zotupa za khansa.

Kusintha kwa majini a PTEN kumatha kubadwa kuchokera kwa makolo anu, kapena mungawapeze mtsogolo kuchokera m'chilengedwe kapena cholakwika chomwe chimachitika mthupi lanu panthawi yama cell.

Kusintha kwa PTEN komwe kumabadwa kumatha kuyambitsa matenda osiyanasiyana. Zina mwa izi zimayamba kuyambira ali wakhanda kapena ali mwana. Ena amawonekera atakula. Matendawa nthawi zambiri amasonkhanitsidwa pamodzi ndipo amatchedwa PTEN hamartoma syndrome (PTHS) ndipo amaphatikizapo:

• Matenda a Cowden, Matenda omwe amachititsa kukula kwa ma hamartomas ambiri ndikuwonjezera chiopsezo cha mitundu ingapo ya khansa, kuphatikiza khansa ya m'mawere, chiberekero, chithokomiro, ndi kholoni. Anthu omwe ali ndi matenda a Cowden nthawi zambiri amakhala ndi mutu wokulirapo (macrocephaly), kuchedwa kwachitukuko, ndi / kapena autism.
• Matenda a Bannayan-Riley-Ruvalcaba imayambitsanso hamartomas ndi macrocephaly. Kuphatikiza apo, anthu omwe ali ndi matendawa atha kukhala ndi zovuta zophunzirira komanso / kapena autism. Amuna omwe ali ndi vutoli nthawi zambiri amakhala ndi madontho akuda pa mbolo.
• Proteus kapena Proteus-ngati matenda Zingayambitse mafupa, khungu, ndi ziwalo zina, komanso hamartomas ndi macrocephaly.

Zomwe zimadziwika (zotchedwanso somatic) PTEN kusintha kwa majini ndi chimodzi mwazomwe zimapezeka mu khansa yamunthu. Zosinthazi zapezeka m'mitundu yambiri ya khansa, kuphatikiza khansa ya prostate, khansa ya m'mimba, ndi mitundu ina ya zotupa zamaubongo.

Mayina ena: PTEN jini, kusanthula kwathunthu kwa majini; Kusanja kwa PTEN ndikuchotsa / kubwereza

Amagwiritsidwa ntchito yanji?

Kuyesaku kumagwiritsidwa ntchito kuyang'ana kusintha kwa majini a PTEN. Sichomwe chimayesedwa nthawi zonse. Nthawi zambiri amaperekedwa kwa anthu kutengera mbiri ya banja, zisonyezo, kapena matenda am'mbuyomu a khansa, makamaka khansa ya m'mawere, chithokomiro, kapena chiberekero.

Chifukwa chiyani ndikufunika kuyesedwa kwa majini a PTEN?

Inu kapena mwana wanu mungafunike kuyesedwa kwa majini a PTEN ngati muli ndi mbiri ya banja la kusintha kwa majini a PTEN ndi / kapena chimodzi kapena zingapo mwa izi:

• Ma hamartomas angapo, makamaka m'mimba
• Macrocephaly (wamkulu kuposa mutu wamba)
• Kuchedwa kwachitukuko
• Satha kulankhula bwinobwino
• Mdima wakuda wa mbolo mwa amuna
• Khansa ya m'mawere
• Khansa ya chithokomiro
• Khansa ya chiberekero mwa akazi

Ngati mwapezeka kuti muli ndi khansa ndipo mulibe mbiri yakubadwa kwa matendawa, omwe amakuthandizani pa zaumoyo wanu akhoza kuyitanitsa mayeso kuti awone ngati kusintha kwa majini a PTEN kungayambitse khansa yanu. Kudziwa ngati muli ndi kusintha kwa thupi kumatha kuthandizira omwe akukuthandizani kulosera momwe matenda anu adzakhalire ndikuwongolera chithandizo chanu.

Kodi chimachitika ndi chiyani poyesa majini a PTEN?

Kuyesedwa kwa PTEN nthawi zambiri kumakhala kuyezetsa magazi. Mukayezetsa magazi, katswiri wa zamankhwala amatenga magazi kuchokera mumtsuko womwe uli m'manja mwanu, pogwiritsa ntchito singano yaying'ono. Singanoyo italowetsedwa, magazi ang'onoang'ono amatengedwa mu chubu choyesera. Mutha kumva kuluma pang'ono singano ikamalowa kapena kutuluka. Izi nthawi zambiri zimatenga mphindi zosakwana zisanu.

Kodi ndiyenera kuchita chilichonse kukonzekera mayeso?

Nthawi zambiri simusowa kukonzekera kwapadera kwa mayeso a PTEN.

Kodi pali zoopsa zilizonse pamayeso?

Pali chiopsezo chochepa kwambiri choyesedwa magazi. Mutha kukhala ndi ululu pang'ono kapena kuvulala pamalo pomwe singano idayikidwapo, koma zizindikiro zambiri zimatha msanga.

Kodi zotsatirazi zikutanthauza chiyani?

Ngati zotsatira zanu zikuwonetsa kuti muli ndi kusintha kwa majini a PTEN, sizitanthauza kuti muli ndi khansa, koma chiopsezo chanu ndichokwera kuposa anthu ambiri. Koma kuwunika kawirikawiri khansa kumatha kuchepetsa ngozi. Khansa imatha kuchiritsidwa ikapezeka koyambirira. Ngati mukusintha, wothandizira zaumoyo wanu angakulimbikitseni chimodzi kapena zingapo za mayesero otsatirawa:

• Colonoscopy, kuyambira zaka 35-40
• Mammogram, kuyambira ali ndi zaka 30 kwa akazi
• Kudziyesa mabere mwezi uliwonse kwa amayi
• Kuwonetsetsa kwa amayi pachiberekero chaka chilichonse
• Kuwonetsa chithokomiro pachaka
• Kufufuza khungu pachaka
• Kuyesa impso pachaka

Chithokomiro chaka ndi chaka komanso kuyezetsa khungu kumalimbikitsidwanso kwa ana omwe ali ndi kusintha kwa majini a PTEN.

Dziwani zambiri zamayeso a labotale, magawo owerengera, ndi zotsatira zakumvetsetsa.

Kodi pali china chilichonse chomwe ndiyenera kudziwa chokhudza kuyesedwa kwa majini a PTEN?

Ngati mwapezeka kuti muli ndi kusintha kwa majini a PTEN kapena mukuganiza zokayezetsa, zingathandize kuyankhula ndi mlangizi wa majini. Phungu wamtundu ndi katswiri wophunzitsidwa mwapadera pama genetics ndi kuyesa kwa majini. Ngati simunayesedwebe, mlangizi akhoza kukuthandizani kumvetsetsa kuopsa ndi maubwino oyesedwa. Ngati mwayesedwa, mlangizi atha kukuthandizani kumvetsetsa zotsatirazo ndikukuwongolerani kuti muthandizire ntchito ndi zinthu zina.

Zolemba

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Zomwe zili patsamba lino siziyenera kugwiritsidwa ntchito m'malo mwa chithandizo chamankhwala kapena upangiri. Lumikizanani ndi othandizira azaumoyo ngati muli ndi mafunso okhudzana ndi thanzi lanu.